{"id":"https://openalex.org/W3167663003","doi":"https://doi.org/10.1159/000514149","title":"The Efficacy of Resin Hemoperfusion Cartridge on Inflammatory Responses during Adult Cardiopulmonary Bypass","display_name":"The Efficacy of Resin Hemoperfusion Cartridge on Inflammatory Responses during Adult Cardiopulmonary Bypass","publication_year":2021,"publication_date":"2021-06-09","ids":{"openalex":"https://openalex.org/W3167663003","doi":"https://doi.org/10.1159/000514149","mag":"3167663003","pmid":"https://pubmed.ncbi.nlm.nih.gov/34107477"},"language":"en","primary_location":{"id":"doi:10.1159/000514149","doi":"https://doi.org/10.1159/000514149","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000514149","pdf_url":null,"source":{"id":"https://openalex.org/S204618219","display_name":"Blood Purification","issn_l":"0253-5068","issn":["0253-5068","1421-9735"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Purification","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043654625","display_name":"Zijian He","orcid":"https://orcid.org/0000-0003-1765-1558","observed_orcids":["https://orcid.org/0000-0003-1765-1558"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zijian He","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103130103","display_name":"Hongyu Lu","orcid":"https://orcid.org/0000-0002-6026-752X","observed_orcids":["https://orcid.org/0000-0002-6026-752X"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongyu Lu","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023553939","display_name":"Xuhua Jian","orcid":"https://orcid.org/0000-0002-8863-6665","observed_orcids":["https://orcid.org/0000-0002-8863-6665"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuhua Jian","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017910487","display_name":"Guanhua Li","orcid":"https://orcid.org/0000-0002-8250-0628","observed_orcids":["https://orcid.org/0000-0002-8250-0628"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210097354","display_name":"Sun Yat-sen Memorial Hospital","ror":"https://ror.org/01px77p81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097354"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guanhua Li","raw_affiliation_strings":["Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210097354"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dengke Xiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dengke Xiao","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111132661","display_name":"Qingqing Meng","orcid":"https://orcid.org/0009-0004-8125-2468","observed_orcids":["https://orcid.org/0009-0004-8125-2468"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingqing Meng","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039491186","display_name":"Jimei Chen","orcid":"https://orcid.org/0000-0002-3278-3842","observed_orcids":["https://orcid.org/0000-0002-3278-3842"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jimei Chen","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101823221","display_name":"Chengbin Zhou","orcid":"https://orcid.org/0000-0002-2059-6417","observed_orcids":["https://orcid.org/0000-0002-2059-6417","https://orcid.org/0000-0002-5011-9750"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chengbin Zhou","raw_affiliation_strings":["Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Surgery, Guangdong Provincial Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.8733,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.94593,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"51","issue":"1","first_page":"31","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11055","display_name":"Cardiac and Coronary Surgery Techniques","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiopulmonary-bypass","display_name":"cardiopulmonary bypass","score":0.9750000238418579},{"id":"https://openalex.org/keywords/systemic-inflammatory-response","display_name":"systemic inflammatory response","score":0.9649999737739563},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.6240000128746033},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.8730000257492065},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.8999999761581421},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.9639999866485596},{"id":"https://openalex.org/keywords/heart-valve-replacement","display_name":"heart valve replacement","score":0.5759999752044678},{"id":"https://openalex.org/keywords/postoperative-recovery","display_name":"postoperative recovery","score":0.7670000195503235},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.574999988079071},{"id":"https://openalex.org/keywords/liver-function","display_name":"liver function","score":0.8050000071525574},{"id":"https://openalex.org/keywords/vasopressor-requirement","display_name":"vasopressor requirement","score":0.972000002861023},{"id":"https://openalex.org/keywords/duration-of-mechanical-ventilation","display_name":"mechanical ventilation duration","score":0.8069999814033508},{"id":"https://openalex.org/keywords/icu-length-of-stay","display_name":"ICU length of stay","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C2781123077","wikidata":"https://www.wikidata.org/wiki/Q3144950","display_name":"Hemoperfusion","level":3,"score":0.9750969409942627},{"id":"https://openalex.org/C2778881276","wikidata":"https://www.wikidata.org/wiki/Q552304","display_name":"Cardiopulmonary bypass","level":2,"score":0.7797058820724487},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7211664915084839},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.656735897064209},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.5579141974449158},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3179062604904175},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27893149852752686},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.1876373291015625}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002315","descriptor_name":"Cardiopulmonary Bypass","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006464","descriptor_name":"Hemoperfusion","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000514149","doi":"https://doi.org/10.1159/000514149","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000514149","pdf_url":null,"source":{"id":"https://openalex.org/S204618219","display_name":"Blood Purification","issn_l":"0253-5068","issn":["0253-5068","1421-9735"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood Purification","raw_type":"journal-article"},{"id":"pmid:34107477","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34107477","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood purification","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1565500246","https://openalex.org/W1604852130","https://openalex.org/W2134544157","https://openalex.org/W2328137612","https://openalex.org/W2344929541","https://openalex.org/W2345461867","https://openalex.org/W2345984830","https://openalex.org/W2409584982","https://openalex.org/W2584756101","https://openalex.org/W2616123874","https://openalex.org/W2618903960","https://openalex.org/W2754703900","https://openalex.org/W2792973203","https://openalex.org/W2807534719","https://openalex.org/W2963367028","https://openalex.org/W2963728831","https://openalex.org/W3017833321"],"related_works":["https://openalex.org/W7148892363","https://openalex.org/W4316193793","https://openalex.org/W7196967363","https://openalex.org/W2072174587","https://openalex.org/W2417843084","https://openalex.org/W4206784577","https://openalex.org/W2586911367","https://openalex.org/W3096742105","https://openalex.org/W1987078321","https://openalex.org/W2328137612"],"abstract_inverted_index":{"AIM:":[0],"This":[1],"study":[2],"aimed":[3],"to":[4,144,183],"evaluate":[5],"the":[6,9,34,46,50,57,114,145,184,195],"efficacy":[7],"of":[8,63,103,110,134,150,152,203],"resin":[10],"hemoperfusion":[11,14,43,190],"device":[12],"(HA380":[13],"cartridge)":[15],"on":[16],"inflammatory":[17,71,197],"responses":[18,198],"during":[19,205],"adult":[20,206],"cardiopulmonary":[21],"bypass":[22],"(CPB).":[23],"METHODS:":[24],"Sixty":[25],"patients":[26,204],"undergoing":[27],"surgical":[28],"valve":[29],"replacement":[30],"were":[31,73],"randomized":[32],"into":[33],"HP":[35,97,128,165],"group":[36,52,98,111,129,166],"(n":[37,53],"=":[38,54],"30)":[39,55],"with":[40,56],"an":[41],"HA380":[42,189],"cartridge":[44,191],"in":[45,113,123,161],"CPB":[47,59],"circuit":[48],"or":[49],"control":[51,146,185],"conventional":[58],"circuit.":[60],"The":[61,96,127,148,164,188],"results":[62],"routine":[64],"blood":[65,67],"tests,":[66],"biochemical":[68],"indexes,":[69],"and":[70,90,106,125,139,155,172,177,199],"factors":[72],"analyzed":[74],"at":[75],"V0":[76],"(pre-CPB),":[77],"V1":[78],"(CPB":[79],"30":[80],"min),":[81],"V2":[82],"(ICU":[83,87,92],"0":[84],"h),":[85,89],"V3":[86],"6":[88],"V4":[91],"24":[93],"h).":[94],"RESULTS:":[95],"had":[99,130,167],"significantly":[100,131,168],"lower":[101,132],"levels":[102,133],"IL-6,":[104],"IL-8,":[105],"IL-10.":[107,126],"Significant":[108],"estimation":[109,149],"differences":[112,151],"generalized":[115],"estimating":[116],"equation":[117],"(GEE)":[118],"models":[119],"was":[120],"also":[121],"observed":[122],"IL-6":[124],"creatinine":[135],"(Cr),":[136],"aminotransferase":[137],"(AST),":[138],"total":[140],"bilirubin":[141],"(TBil)":[142],"compared":[143,182],"group.":[147,186],"Cr,":[153],"AST,":[154],"TBil":[156],"all":[157],"reached":[158],"statistical":[159],"significance":[160],"GEE":[162],"results.":[163],"less":[169],"vasopressor":[170],"requirement":[171],"shorter":[173],"mechanical":[174],"ventilation":[175],"time":[176,180],"ICU":[178],"stay":[179],"as":[181],"CONCLUSION:":[187],"could":[192],"effectively":[193],"reduce":[194],"systemic":[196],"improve":[200],"postoperative":[201],"recovery":[202],"CPB.":[207]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-06-22T00:00:00"}