{"id":"https://openalex.org/W3162789529","doi":"https://doi.org/10.1161/circ.142.suppl_3.17400","title":"Abstract 17400: Using Electronic Health Records for Predicting Hospitalization of COVID-19 Patients in Massachusetts","display_name":"Abstract 17400: Using Electronic Health Records for Predicting Hospitalization of COVID-19 Patients in Massachusetts","publication_year":2020,"publication_date":"2020-11-17","ids":{"openalex":"https://openalex.org/W3162789529","doi":"https://doi.org/10.1161/circ.142.suppl_3.17400","mag":"3162789529"},"language":"en","primary_location":{"id":"doi:10.1161/circ.142.suppl_3.17400","doi":"https://doi.org/10.1161/circ.142.suppl_3.17400","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.142.suppl_3.17400","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004746584","display_name":"Hesam Dashti","orcid":"https://orcid.org/0000-0003-4566-0582","observed_orcids":["https://orcid.org/0000-0003-4566-0582"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hesam Dashti","raw_affiliation_strings":["Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","Hesam Dashti Brigham and Women's Hosp, Harvard Med Sch, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Hesam Dashti Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062537038","display_name":"Elise C. Roche","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elise C. Roche","raw_affiliation_strings":["Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","Elise C. Roche Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Elise C. Roche Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036110536","display_name":"David Westfall Bates","orcid":"https://orcid.org/0000-0001-6268-1540","observed_orcids":["https://orcid.org/0000-0001-6268-1540","https://orcid.org/0000-0003-4850-2360","https://orcid.org/0000-0001-7438-9491","https://orcid.org/0000-0002-3105-156X","https://orcid.org/0000-0001-5440-6039"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David W. Bates","raw_affiliation_strings":["Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","David W. Bates Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"David W. Bates Div of Preventive Medicine, Brigham and Women's Hosp, Harvard Med Sch, Boston, MA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084857746","display_name":"Nancy R. Cook","orcid":"https://orcid.org/0000-0002-9705-0842","observed_orcids":["https://orcid.org/0000-0002-9705-0842"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy R Cook","raw_affiliation_strings":["BRIGHAM AND WOMENS HOSPITAL, Boston, MA","Nancy R Cook BRIGHAM AND WOMENS HOSPITAL, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BRIGHAM AND WOMENS HOSPITAL, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Nancy R Cook BRIGHAM AND WOMENS HOSPITAL, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074749823","display_name":"Samia Mora","orcid":"https://orcid.org/0000-0001-6283-0980","observed_orcids":["https://orcid.org/0000-0001-6283-0980"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samia Mora","raw_affiliation_strings":["BRIGHAM AND WOMENS HOSPITAL, Boston, MA","Samia Mora BRIGHAM AND WOMENS HOSPITAL, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BRIGHAM AND WOMENS HOSPITAL, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Samia Mora BRIGHAM AND WOMENS HOSPITAL, Boston, MA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091746574","display_name":"Olga Demler","orcid":"https://orcid.org/0000-0003-3355-3210","observed_orcids":["https://orcid.org/0000-0003-3355-3210"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olga Demler","raw_affiliation_strings":["Brigham and Women's Hosp, Brookline, MA","Olga Demler Brigham and Women's Hosp, Brookline, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brigham and Women's Hosp, Brookline, MA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Olga Demler Brigham and Women's Hosp, Brookline, MA","institution_ids":["https://openalex.org/I1283280774"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"142","issue":"Suppl_3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.023099999874830246,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hospitalization-risk-prediction","display_name":"hospitalization risk prediction","score":0.9100000262260437},{"id":"https://openalex.org/keywords/electronic-health-records","display_name":"electronic health records","score":0.9940000176429749},{"id":"https://openalex.org/keywords/clinical-risk-factors","display_name":"clinical risk factors","score":0.4869999885559082},{"id":"https://openalex.org/keywords/heparin","display_name":"heparin","score":0.781000018119812},{"id":"https://openalex.org/keywords/erythropoietin","display_name":"erythropoietin","score":0.9810000061988831},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.996999979019165},{"id":"https://openalex.org/keywords/albumin","display_name":"albumin","score":0.8450000286102295},{"id":"https://openalex.org/keywords/white-blood-cell-count","display_name":"white blood cell count","score":0.996999979019165},{"id":"https://openalex.org/keywords/generalized-linear-models","display_name":"generalized linear models","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8381677865982056},{"id":"https://openalex.org/C126674687","wikidata":"https://www.wikidata.org/wiki/Q1662573","display_name":"Akaike information criterion","level":2,"score":0.8080261945724487},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.7329761385917664},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.6738716959953308},{"id":"https://openalex.org/C3019952477","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Health records","level":3,"score":0.614331841468811},{"id":"https://openalex.org/C3020144179","wikidata":"https://www.wikidata.org/wiki/Q10871684","display_name":"Electronic health record","level":3,"score":0.5434941649436951},{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.49008166790008545},{"id":"https://openalex.org/C3018060332","wikidata":"https://www.wikidata.org/wiki/Q10871684","display_name":"Electronic medical record","level":2,"score":0.4766277074813843},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.4335373640060425},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3884347379207611},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3267019987106323},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.22227022051811218},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.17973855137825012},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.10512310266494751},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/circ.142.suppl_3.17400","doi":"https://doi.org/10.1161/circ.142.suppl_3.17400","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.142.suppl_3.17400","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4206899890","https://openalex.org/W3130739735","https://openalex.org/W3188449234","https://openalex.org/W4387837120","https://openalex.org/W4312732487","https://openalex.org/W3170950621","https://openalex.org/W3005015612","https://openalex.org/W3164012388","https://openalex.org/W4287416782","https://openalex.org/W4283521549"],"abstract_inverted_index":{"Introduction:":[0],"The":[1,37,183,205],"electronic":[2],"health":[3],"record":[4],"(EHR)":[5],"provides":[6],"a":[7,141,167,172],"platform":[8],"to":[9,43,58,81,93,134,148,165,267],"design":[10],"models":[11],"for":[12,53,73,157],"predicting":[13,158],"the":[14,23,60,71,97,122,153,175,191,195,219,278],"severity":[15],"of":[16,39,46,76,174,177,194,213,224,232,261,270,277],"illness":[17],"in":[18,48],"COVID-19":[19,67,99,262,273],"patients.":[20,68,274],"We":[21,69,126],"used":[22,127,164],"Mass":[24],"General":[25],"Brigham":[26],"(MGB)":[27],"EHR":[28,62,72,209,259],"that":[29,151,197],"contains":[30,198],"records":[31,75,91,117,133],"mostly":[32],"from":[33,79,118],"greater":[34],"Boston,":[35],"Massachusetts.":[36],"objective":[38],"this":[40],"research":[41],"is":[42,284],"predict":[44,268],"risk":[45,212,234,269],"hospitalization":[47,214,233,271],"patients":[49,78,104,128,263],"who":[50,105],"tested":[51,189],"positive":[52,100,124],"COVID-19.":[54],"Methods:":[55],"Between":[56],"01/01/2020":[57],"05/11/2020":[59],"MGB":[61,178,199],"contained":[63],"8,213":[64],"laboratory-":[65],"confirmed":[66],"queried":[70],"medical":[74,86,132],"these":[77],"12/31/2015":[80],"05/11/2020.":[82],"To":[83,102],"examine":[84],"pre-COVID-19":[85],"history,":[87],"we":[88,114],"considered":[89],"latest":[90],"prior":[92,241],"21":[94],"days":[95,120],"before":[96,108,121],"first":[98,123],"test.":[101,125],"consider":[103],"were":[106,163],"hospitalized":[107],"their":[109],"test":[110],"results":[111],"become":[112],"available,":[113],"analyzed":[115],"admission":[116],"7":[119],"with":[129,216],"no":[130],"missing":[131],"construct":[135],"our":[136],"dataset":[137,176,196],"(N=2,783)":[138],"and":[139,246,249,253],"conducted":[140],"forward":[142],"feature":[143],"selection":[144],"on":[145,171,190,208,281],"51":[146],"variables":[147,237],"identify":[149],"markers":[150,161],"minimized":[152],"Akaike":[154],"information":[155],"criterion":[156],"hospitalization.":[159],"These":[160],"then":[162,188],"train":[166],"generalized":[168],"linear":[169],"model":[170,186,206,280],"subset":[173,193],"non-employees":[179],"(N=2,367;":[180],"56%":[181],"hospitalized).":[182,203],"trained":[184],"predictive":[185,279],"was":[187],"remaining":[192],"employees":[200],"(N=416;":[201],"17%":[202],"Results:":[204],"based":[207],"data":[210,260],"predicted":[211],"well,":[215],"area":[217],"under":[218],"curve":[220],"(AUC,":[221],"DeLong":[222],"method)":[223],"0.76":[225],"[95%":[226],"CI:":[227],"0.7002-0.8206],":[228],"Figure.":[229],"Significant":[230],"determinants":[231],"included":[235],"demographic":[236],"(age,":[238],"sex,":[239],"race),":[240],"medication":[242],"use":[243],"(heparin,":[244],"erythropoietin,":[245],"beta":[247],"blockers),":[248],"lab":[250],"tests":[251],"(albumin":[252],"white":[254],"blood":[255],"cell":[256],"counts).":[257],"Conclusions:":[258],"can":[264],"be":[265],"leveraged":[266],"among":[272],"Further":[275],"validation":[276],"other":[282],"cohorts":[283],"needed.":[285]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2021-05-24T00:00:00"}