{"id":"https://openalex.org/W3160778596","doi":"https://doi.org/10.1111/liv.14936","title":"Fresh frozen plasma transfusion in acute variceal haemorrhage: Results from a multicentre cohort study","display_name":"Fresh frozen plasma transfusion in acute variceal haemorrhage: Results from a multicentre cohort study","publication_year":2021,"publication_date":"2021-05-09","ids":{"openalex":"https://openalex.org/W3160778596","doi":"https://doi.org/10.1111/liv.14936","mag":"3160778596","pmid":"https://pubmed.ncbi.nlm.nih.gov/33969607"},"language":"en","primary_location":{"id":"doi:10.1111/liv.14936","doi":"https://doi.org/10.1111/liv.14936","is_oa":false,"landing_page_url":"https://doi.org/10.1111/liv.14936","pdf_url":null,"source":{"id":"https://openalex.org/S206392846","display_name":"Liver International","issn_l":"0106-9543","issn":["0106-9543","1478-3223","1478-3231","1600-0676"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063580480","display_name":"Arpan Mohanty","orcid":"https://orcid.org/0000-0002-8408-8075","observed_orcids":["https://orcid.org/0000-0002-8408-8075"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1286490081","display_name":"Boston Medical Center","ror":"https://ror.org/010b9wj87","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1286490081"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Arpan Mohanty","raw_affiliation_strings":["Section of Gastroenterology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8408-8075","affiliations":[{"raw_affiliation_string":"Section of Gastroenterology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082771744","display_name":"Devika Kapuria","orcid":"https://orcid.org/0000-0001-9565-9868","observed_orcids":["https://orcid.org/0000-0001-9565-9868"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Devika Kapuria","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM, USA"],"raw_orcid":"https://orcid.org/0000-0001-9565-9868","affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073981295","display_name":"Andrew Canakis","orcid":"https://orcid.org/0000-0002-6646-6693","observed_orcids":["https://orcid.org/0000-0002-6646-6693"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1286490081","display_name":"Boston Medical Center","ror":"https://ror.org/010b9wj87","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1286490081"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Canakis","raw_affiliation_strings":["Department of Internal Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017261731","display_name":"Honghuang Lin","orcid":"https://orcid.org/0000-0003-3043-3942","observed_orcids":["https://orcid.org/0000-0003-3043-3942"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1286490081","display_name":"Boston Medical Center","ror":"https://ror.org/010b9wj87","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1286490081"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Honghuang Lin","raw_affiliation_strings":["Section of Computational Biomedicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Computational Biomedicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062122300","display_name":"Maelys J. Amat","orcid":"https://orcid.org/0000-0002-6031-8067","observed_orcids":["https://orcid.org/0000-0002-6031-8067"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maelys J. Amat","raw_affiliation_strings":["Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025948664","display_name":"Graziella Rangel Paniz","orcid":"https://orcid.org/0000-0002-3890-2443","observed_orcids":["https://orcid.org/0000-0002-3890-2443"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Graziella Rangel Paniz","raw_affiliation_strings":["Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059367234","display_name":"Nicholas Placone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas T. Placone","raw_affiliation_strings":["Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, CA, USA","institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091008296","display_name":"Reggie R. Thomasson","orcid":"https://orcid.org/0000-0002-3986-571X","observed_orcids":["https://orcid.org/0000-0002-3986-571X"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I1286490081","display_name":"Boston Medical Center","ror":"https://ror.org/010b9wj87","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1286490081"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Reggie Thomasson","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062415571","display_name":"Hemant K. Roy","orcid":"https://orcid.org/0000-0002-6342-6768","observed_orcids":["https://orcid.org/0000-0002-6342-6768","https://orcid.org/0000-0001-7613-5575"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hemant Roy","raw_affiliation_strings":["Department of Medicine, Baylor College of Medicine, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Baylor College of Medicine, Houston, TX, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049228255","display_name":"Eric Chak","orcid":"https://orcid.org/0000-0001-6182-8002","observed_orcids":["https://orcid.org/0000-0001-6182-8002"]},"institutions":[{"id":"https://openalex.org/I4210160527","display_name":"University of California Davis Medical Center","ror":"https://ror.org/05t6gpm70","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210160527","https://openalex.org/I4210160856"]},{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Chak","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, CA, USA"],"raw_orcid":"https://orcid.org/0000-0001-6182-8002","affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, University of California Davis School of Medicine, Sacramento, CA, USA","institution_ids":["https://openalex.org/I4210160527","https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034304250","display_name":"Gy\u00f6rgy Baffy","orcid":"https://orcid.org/0000-0002-8334-0400","observed_orcids":["https://orcid.org/0000-0002-8334-0400"]},"institutions":[{"id":"https://openalex.org/I2801671727","display_name":"VA Boston Healthcare System","ror":"https://ror.org/04v00sg98","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2801671727","https://openalex.org/I4210095851"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gyorgy Baffy","raw_affiliation_strings":["Department of Medicine, VA Boston Healthcare System, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, VA Boston Healthcare System, Boston, MA, USA","institution_ids":["https://openalex.org/I2801671727"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049686350","display_name":"Michael P. Curry","orcid":"https://orcid.org/0000-0003-2110-3503","observed_orcids":["https://orcid.org/0000-0003-2110-3503"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael P. Curry","raw_affiliation_strings":["Division of Gastroenterology/Liver Center, Beth Israel Deaconess Medical Center, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology/Liver Center, Beth Israel Deaconess Medical Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009097451","display_name":"Loren Laine","orcid":"https://orcid.org/0000-0002-4296-7901","observed_orcids":["https://orcid.org/0000-0002-4296-7901"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210086971","display_name":"VA Connecticut Healthcare System","ror":"https://ror.org/000rgm762","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210086971","https://openalex.org/I4210095851"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Loren Laine","raw_affiliation_strings":["Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA","Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Digestive Diseases, Yale School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA","institution_ids":["https://openalex.org/I4210086971"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013248682","display_name":"Tarun Rustagi","orcid":"https://orcid.org/0000-0001-8582-011X","observed_orcids":["https://orcid.org/0000-0001-8582-011X"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tarun Rustagi","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, University of New Mexico, Albuquerque, NM, USA","institution_ids":["https://openalex.org/I169521973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5063580480"],"corresponding_institution_ids":["https://openalex.org/I111088046","https://openalex.org/I1286490081"],"apc_list":{"value":4100,"currency":"USD","value_usd":4100},"apc_paid":null,"fwci":8.8157,"has_fulltext":false,"cited_by_count":94,"citation_normalized_percentile":{"value":0.98878941,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"41","issue":"8","first_page":"1901","last_page":"1908"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fresh-frozen-plasma","display_name":"fresh frozen plasma","score":0.8399999737739563},{"id":"https://openalex.org/keywords/portal-hypertension","display_name":"portal hypertension","score":0.6690000295639038},{"id":"https://openalex.org/keywords/bleeding-complications","display_name":"bleeding complications","score":0.4189999997615814},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8230000138282776},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.6679999828338623},{"id":"https://openalex.org/keywords/meld-score","display_name":"MELD score","score":0.7480000257492065},{"id":"https://openalex.org/keywords/blood-transfusion-outcomes","display_name":"blood transfusion outcomes","score":0.6010000109672546}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9598940014839172},{"id":"https://openalex.org/C66112548","wikidata":"https://www.wikidata.org/wiki/Q1225698","display_name":"Fresh frozen plasma","level":3,"score":0.8408057689666748},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.6908557415008545},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.5794470906257629},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5448725819587708},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5343177914619446},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5007290840148926},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.47378823161125183},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4474916458129883},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4302852749824524},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D004932","descriptor_name":"Esophageal and Gastric Varices","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D004932","descriptor_name":"Esophageal and Gastric Varices","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006471","descriptor_name":"Gastrointestinal Hemorrhage","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006471","descriptor_name":"Gastrointestinal Hemorrhage","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010949","descriptor_name":"Plasma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016913","descriptor_name":"Blood Component Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058625","descriptor_name":"End Stage Liver Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/liv.14936","doi":"https://doi.org/10.1111/liv.14936","is_oa":false,"landing_page_url":"https://doi.org/10.1111/liv.14936","pdf_url":null,"source":{"id":"https://openalex.org/S206392846","display_name":"Liver International","issn_l":"0106-9543","issn":["0106-9543","1478-3223","1478-3231","1600-0676"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver International","raw_type":"journal-article"},{"id":"pmid:33969607","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33969607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Liver international : official journal of the International Association for the Study of the Liver","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G214657994","display_name":"Unraveling Racial Disparities in Portal Hypertension: A Clinical, Spectroscopic andSNP Approach","funder_award_id":"R21MD013631","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"}],"funders":[{"id":"https://openalex.org/F4320337534","display_name":"National Institute on Minority Health and Health Disparities","ror":"https://ror.org/0493hgw16"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W571628560","https://openalex.org/W1784460170","https://openalex.org/W1981783866","https://openalex.org/W1990276802","https://openalex.org/W2016483873","https://openalex.org/W2046521127","https://openalex.org/W2074863268","https://openalex.org/W2078378195","https://openalex.org/W2079541027","https://openalex.org/W2115341338","https://openalex.org/W2129838212","https://openalex.org/W2142333500","https://openalex.org/W2144187145","https://openalex.org/W2146837707","https://openalex.org/W2147368252","https://openalex.org/W2155510757","https://openalex.org/W2166018647","https://openalex.org/W2168333649","https://openalex.org/W2170591435","https://openalex.org/W2170740817","https://openalex.org/W2337594243","https://openalex.org/W2359884680","https://openalex.org/W2407179889","https://openalex.org/W2477913293","https://openalex.org/W2508848555","https://openalex.org/W2546046192","https://openalex.org/W2612977672","https://openalex.org/W2802906787","https://openalex.org/W2809833128","https://openalex.org/W2884656642","https://openalex.org/W2886985238","https://openalex.org/W2973851317","https://openalex.org/W3036330637","https://openalex.org/W3100643077"],"related_works":["https://openalex.org/W4224285627","https://openalex.org/W3162032060","https://openalex.org/W3162825019","https://openalex.org/W3211408501","https://openalex.org/W2129819526","https://openalex.org/W3093935434","https://openalex.org/W2804516464","https://openalex.org/W2948411409","https://openalex.org/W7127902334","https://openalex.org/W1882157988"],"abstract_inverted_index":{"BACKGROUND:":[0],"Fresh":[1,218],"frozen":[2,219],"plasma":[3,220],"(FFP)":[4],"transfusion":[5,28,76,103,130,139,160,194,221],"is":[6,224],"often":[7],"used":[8,69],"in":[9,32,210,222,255],"the":[10,72,202],"management":[11],"of":[12,44,74,94,145,179,192],"acute":[13],"variceal":[14,121],"haemorrhage":[15],"(AVH)":[16],"despite":[17],"best":[18],"practice":[19],"advice":[20],"suggesting":[21],"otherwise.":[22],"OBJECTIVE:":[23],"We":[24,38],"investigated":[25],"if":[26],"FFP":[27,75,102,129,138,159,193,253],"affects":[29],"clinical":[30,229],"outcomes":[31],"AVH.":[33,61,256],"DESIGN,":[34],"SETTING":[35],"AND":[36,216],"PATIENTS:":[37],"performed":[39],"a":[40],"retrospective":[41],"cohort":[42,203],"study":[43,71],"244":[45],"consecutive,":[46],"eligible":[47],"patients":[48,208,211],"admitted":[49],"to":[50,70,86,166,206,242],"five":[51],"tertiary":[52],"health":[53],"care":[54],"centres":[55],"between":[56],"2013":[57],"and":[58,84,92,118,177,209,249],"2018":[59],"with":[60,77,142,164,195,227,252],"MAIN":[62],"OUTCOME":[63],"MEASUREMENTS:":[64],"Multivariable":[65,134],"regression":[66],"analyses":[67],"were":[68],"association":[73,191],"mortality":[78,146,196],"at":[79,89,147,169,197],"42":[80,148,198],"days":[81,91,149,171,182,199],"(primary":[82],"outcome)":[83],"failure":[85,165],"control":[87,167],"bleeding":[88,122,168],"5":[90,170],"length":[93,178],"stay":[95,180],"(secondary":[96],"outcomes).":[97],"RESULTS:":[98],"Patients":[99],"who":[100,125],"received":[101,128],"(n":[104,131],"=":[105,132],"100)":[106],"had":[107],"higher":[108],"mean":[109],"Model":[110],"for":[111],"End":[112],"Stage":[113],"Liver":[114],"Disease":[115],"(MELD)":[116],"score":[117],"more":[119],"severe":[120],"than":[123],"those":[124],"did":[126],"not":[127],"144).":[133],"analysis":[135],"showed":[136],"that":[137],"was":[140,161,204],"associated":[141,163,226],"increased":[143],"odds":[144],"(odds":[150],"ratio":[151],"[OR]":[152],"9.41,":[153],"95%":[154,174,186],"confidence":[155],"interval":[156],"[CI]":[157],"3.71-23.90).":[158],"also":[162],"(OR":[172],"3.87,":[173],"CI":[175,187],"1.28-11.70)":[176],">7":[181],"(adjusted":[183],"OR":[184],"1.88,":[185],"1.03-3.42).":[188],"The":[189],"independent":[190],"persisted":[200],"when":[201],"restricted":[205],"high-risk":[207],"without":[212],"active":[213],"bleeding.":[214],"LIMITATIONS":[215],"CONCLUSIONS:":[217],"AVH":[223],"independently":[225],"poor":[228],"outcomes.":[230],"As":[231],"this":[232],"an":[233],"observational":[234],"study,":[235],"there":[236],"may":[237],"be":[238],"residual":[239],"bias":[240],"due":[241],"confounding;":[243],"however,":[244],"we":[245],"demonstrate":[246],"no":[247],"benefit":[248],"potential":[250],"harm":[251],"transfusions":[254]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":25},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":7},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-05-24T00:00:00"}