{"id":"https://openalex.org/W3159514958","doi":"https://doi.org/10.1210/jendso/bvab048.1299","title":"Vertebral Fractures Occur Regardless of Acromegaly Activity and Are Best Predicted by Proximal Femur Cortical Volumetric Bone Mineral Density","display_name":"Vertebral Fractures Occur Regardless of Acromegaly Activity and Are Best Predicted by Proximal Femur Cortical Volumetric Bone Mineral Density","publication_year":2021,"publication_date":"2021-05-01","ids":{"openalex":"https://openalex.org/W3159514958","doi":"https://doi.org/10.1210/jendso/bvab048.1299","mag":"3159514958"},"language":"en","primary_location":{"id":"doi:10.1210/jendso/bvab048.1299","doi":"https://doi.org/10.1210/jendso/bvab048.1299","is_oa":true,"landing_page_url":"https://doi.org/10.1210/jendso/bvab048.1299","pdf_url":"https://academic.oup.com/jes/article-pdf/5/Supplement_1/A638/37206402/bvab048.1299.pdf","source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/jes/article-pdf/5/Supplement_1/A638/37206402/bvab048.1299.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036980097","display_name":"Martin Ku\u017ema","orcid":"https://orcid.org/0000-0002-1294-1217","observed_orcids":["https://orcid.org/0000-0002-1294-1217"]},"institutions":[{"id":"https://openalex.org/I4210095125","display_name":"University Hospital Bratislava","ror":"https://ror.org/00pspca89","country_code":"SK","type":"healthcare","lineage":["https://openalex.org/I4210095125"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Martin Kuzma","raw_affiliation_strings":["University Hospital Bratislava, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Bratislava, Bratislava, Slovakia","institution_ids":["https://openalex.org/I4210095125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035836380","display_name":"Peter Va\u0148uga","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Vanuga","raw_affiliation_strings":["National institute of Endocrinology and Diabetology, Lubochna, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National institute of Endocrinology and Diabetology, Lubochna, Slovakia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081654922","display_name":"Ivana S\u00e1gov\u00e1","orcid":"https://orcid.org/0000-0001-9120-8867","observed_orcids":["https://orcid.org/0000-0001-9120-8867"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ivana Sagova","raw_affiliation_strings":["National institute of Endocrinology and Diabetology, Lubochna, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National institute of Endocrinology and Diabetology, Lubochna, Slovakia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047133479","display_name":"Du\u0161an P\u00e1vai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dusan Pavai","raw_affiliation_strings":["National institute of Endocrinology and Diabetology, Lubochna, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National institute of Endocrinology and Diabetology, Lubochna, Slovakia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056041733","display_name":"Peter Jackuliak","orcid":"https://orcid.org/0000-0002-1348-3721","observed_orcids":["https://orcid.org/0000-0002-1348-3721"]},"institutions":[{"id":"https://openalex.org/I4210095125","display_name":"University Hospital Bratislava","ror":"https://ror.org/00pspca89","country_code":"SK","type":"healthcare","lineage":["https://openalex.org/I4210095125"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Peter Jackuliak","raw_affiliation_strings":["University Hospital Bratislava, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Bratislava, Bratislava, Slovakia","institution_ids":["https://openalex.org/I4210095125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002170070","display_name":"Zdenko Killinger","orcid":"https://orcid.org/0000-0002-4144-5589","observed_orcids":["https://orcid.org/0000-0002-4144-5589"]},"institutions":[{"id":"https://openalex.org/I4210095125","display_name":"University Hospital Bratislava","ror":"https://ror.org/00pspca89","country_code":"SK","type":"healthcare","lineage":["https://openalex.org/I4210095125"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Zdenko Killinger","raw_affiliation_strings":["University Hospital Bratislava, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Bratislava, Bratislava, Slovakia","institution_ids":["https://openalex.org/I4210095125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070407771","display_name":"Neil Binkley","orcid":"https://orcid.org/0000-0002-9905-461X","observed_orcids":["https://orcid.org/0000-0002-9905-461X"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil Binkley","raw_affiliation_strings":["University of Wisconsin, Madison, WI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Wisconsin, Madison, WI, USA","institution_ids":["https://openalex.org/I135310074"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020420660","display_name":"Renaud Winzenrieth","orcid":"https://orcid.org/0000-0002-2755-6063","observed_orcids":["https://orcid.org/0000-0002-2755-6063"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Renaud Winzenrieth","raw_affiliation_strings":["Galgo Medical, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Galgo Medical, Barcelona, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042012204","display_name":"Harry K. Genant","orcid":"https://orcid.org/0000-0002-6002-2020","observed_orcids":["https://orcid.org/0000-0002-6002-2020"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harry K Genant","raw_affiliation_strings":["University of California, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087190566","display_name":"Juraj Payer","orcid":"https://orcid.org/0000-0002-4977-6817","observed_orcids":["https://orcid.org/0000-0002-4977-6817","https://orcid.org/0000-0002-9221-4625"]},"institutions":[{"id":"https://openalex.org/I4210095125","display_name":"University Hospital Bratislava","ror":"https://ror.org/00pspca89","country_code":"SK","type":"healthcare","lineage":["https://openalex.org/I4210095125"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Juraj Payer","raw_affiliation_strings":["University Hospital Bratislava, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Bratislava, Bratislava, Slovakia","institution_ids":["https://openalex.org/I4210095125"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2625,"currency":"USD","value_usd":2625},"apc_paid":{"value":2625,"currency":"USD","value_usd":2625},"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"Supplement_1","first_page":"A638","last_page":"A638"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9301999807357788,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.05299999937415123,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acromegaly","display_name":"acromegaly","score":0.8759999871253967},{"id":"https://openalex.org/keywords/vertebral-fractures","display_name":"vertebral fractures","score":0.9900000095367432},{"id":"https://openalex.org/keywords/cortical-bone-mineral-density","display_name":"cortical bone mineral density","score":0.7319999933242798},{"id":"https://openalex.org/keywords/trabecular-bone-score","display_name":"trabecular bone score","score":0.8159999847412109},{"id":"https://openalex.org/keywords/proximal-femur","display_name":"proximal femur","score":0.7789999842643738},{"id":"https://openalex.org/keywords/fracture-risk-prediction","display_name":"fracture risk prediction","score":0.8009999990463257},{"id":"https://openalex.org/keywords/cortical-thickness","display_name":"cortical thickness","score":0.6320000290870667},{"id":"https://openalex.org/keywords/bone-turnover-markers","display_name":"bone turnover markers","score":0.6919999718666077},{"id":"https://openalex.org/keywords/impaired-glucose-tolerance","display_name":"impaired glucose tolerance","score":0.75},{"id":"https://openalex.org/keywords/insulin-like-growth-factor-i","display_name":"insulin-like growth factor I","score":0.8550000190734863},{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.949999988079071},{"id":"https://openalex.org/keywords/dual-energy-x-ray-absorptiometry","display_name":"dual-energy X-ray absorptiometry","score":0.824999988079071}],"concepts":[{"id":"https://openalex.org/C2777433750","wikidata":"https://www.wikidata.org/wiki/Q189580","display_name":"Acromegaly","level":4,"score":0.8848129510879517},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8691608905792236},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.7450188398361206},{"id":"https://openalex.org/C2781451080","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cortical bone","level":2,"score":0.5297539830207825},{"id":"https://openalex.org/C2775854910","wikidata":"https://www.wikidata.org/wiki/Q4844892","display_name":"Femoral neck","level":3,"score":0.4930817782878876},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.45066535472869873},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.4479047954082489},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.432623028755188},{"id":"https://openalex.org/C2777425516","wikidata":"https://www.wikidata.org/wiki/Q17083560","display_name":"Quantitative computed tomography","level":4,"score":0.4322623312473297},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42089593410491943},{"id":"https://openalex.org/C2776169692","wikidata":"https://www.wikidata.org/wiki/Q4941552","display_name":"Bone disease","level":3,"score":0.4114891290664673},{"id":"https://openalex.org/C131075544","wikidata":"https://www.wikidata.org/wiki/Q415863","display_name":"Osteocalcin","level":4,"score":0.4103561043739319},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34418076276779175},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.19761469960212708},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.17969214916229248},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.10084947943687439},{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1210/jendso/bvab048.1299","doi":"https://doi.org/10.1210/jendso/bvab048.1299","is_oa":true,"landing_page_url":"https://doi.org/10.1210/jendso/bvab048.1299","pdf_url":"https://academic.oup.com/jes/article-pdf/5/Supplement_1/A638/37206402/bvab048.1299.pdf","source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8090376","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8090376","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Endocr Soc","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1210/jendso/bvab048.1299","doi":"https://doi.org/10.1210/jendso/bvab048.1299","is_oa":true,"landing_page_url":"https://doi.org/10.1210/jendso/bvab048.1299","pdf_url":"https://academic.oup.com/jes/article-pdf/5/Supplement_1/A638/37206402/bvab048.1299.pdf","source":{"id":"https://openalex.org/S2735747656","display_name":"Journal of the Endocrine Society","issn_l":"2472-1972","issn":["2472-1972"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310315851","host_organization_name":"Endocrine Society","host_organization_lineage":["https://openalex.org/P4310315851"],"host_organization_lineage_names":["Endocrine Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Endocrine Society","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3159514958.pdf","grobid_xml":"https://content.openalex.org/works/W3159514958.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3180018772","https://openalex.org/W4417163338","https://openalex.org/W2905563255","https://openalex.org/W2008252191","https://openalex.org/W2150399593","https://openalex.org/W2944139267","https://openalex.org/W2070343051","https://openalex.org/W4411375104","https://openalex.org/W2771440762","https://openalex.org/W2142417862"],"abstract_inverted_index":{"Abstract":[0],"Introduction:":[1],"Vertebral":[2],"fractures":[3],"(VFs)":[4],"in":[5,40,97,204,235,239,290,309],"patients":[6,77,221,231],"with":[7,12,161,193,225,268,278,322],"acromegaly":[8,26,63,76,313],"are":[9],"not":[10],"associated":[11,85,277,321],"bone":[13,23,34,55,94,306,332],"mineral":[14],"density":[15],"(BMD)":[16],"decrease.":[17],"Previous":[18],"studies":[19,30],"showed":[20,255],"impaired":[21],"trabecular":[22,136,244,331],"parameters":[24,57,264],"among":[25,62,312],"patients.":[27,64,314],"However,":[28],"recent":[29],"suggest":[31],"that":[32,304],"cortical":[33,138,142,147,211,242,256,291,305],"could":[35,328],"also":[36],"play":[37],"a":[38,162,201],"role":[39],"VF":[41,60,150,302],"development.":[42],"Objective:":[43],"Evaluate":[44],"the":[45,155,294],"utility":[46],"of":[47,75,79,223,252,300],"dual":[48],"energy":[49],"x-ray":[50],"absorptiometry":[51],"(DXA)":[52],"BMD":[53,114,145],"and":[54,66,93,110,118,137,146,179,209,237,243,248,260,271,297],"structural":[56],"to":[58,132,330],"determine":[59],"risk":[61],"Patients":[65],"Methods:":[67],"A":[68],"single-center":[69],"two":[70,174,199],"years":[71,200],"prospective":[72],"follow":[73],"up":[74],"regardless":[78],"age,":[80],"gender,":[81],"disease":[82,195],"activity":[83],"or":[84],"treatments":[86],"was":[87,130,152,216,275,293,318],"conducted.":[88],"Pituitary":[89],"hormones,":[90],"glucose":[91,281,323,326],"metabolism":[92],"turnover":[95],"markers":[96],"all":[98,214],"subjects":[99,184],"were":[100,171,196],"assessed.":[101],"Each":[102],"subject":[103],"had":[104,232],"L1-4":[105],"spine,":[106],"femoral":[107],"neck":[108,261],"(FN)":[109],"total":[111],"hip":[112],"(TH)":[113],"measured":[115],"using":[116,154,166],"DXA,":[117],"TBS":[119,274,317],"measurement":[120],"performed":[121,153],"\u00b1":[122],"7":[123],"days":[124],"from":[125],"blood":[126],"sampling.":[127],"3D":[128],"Shaper":[129],"used":[131],"assess":[133],"proximal":[134],"femur":[135],"volumetric":[139],"(v)":[140],"BMD,":[141],"surface":[143],"(s)":[144],"thickness":[148],"(Cth).":[149],"assessment":[151],"lateral":[156],"spine":[157],"imaging":[158],"IVA\u2122":[159],"mode":[160],"Hologic":[163],"Horizon\u00ae":[164],"densitometer":[165],"semi-quantitative":[167],"approach.":[168],"Study":[169],"outcomes":[170],"assessed":[172],"at":[173,246,258,284],"time":[175,286],"points":[176],"-":[177],"baseline":[178],"month":[180],"24.":[181],"Results:":[182],"Seventy":[183],"(34":[185],"M/36F),":[186],"mean":[187],"age":[188],"55.1":[189],"years,":[190],"including":[191],"26":[192],"active":[194],"studied.":[197],"After":[198],"significant":[202],"decrease":[203,238],"IGF-1":[205],"(-30%),":[206],"osteocalcin":[207],"(-18%)":[208],"TH":[210,247,259],"vBMD":[212,245,257,292],"(-3%;":[213],"p\u22640.05)":[215],"observed.":[217],"During":[218],"follow-up,":[219],"13":[220],"nine":[222],"them":[224],"controlled":[226],"disease,":[227],"developed":[228],"VF;":[229],"these":[230],"greater":[233],"increase":[234],"CTx":[236],"TBS,":[240],"sBMD,":[241],"neck.":[249],"Multivariate":[250],"analysis":[251],"fracture":[253,266,310],"prediction":[254,267],"as":[262],"best":[263],"for":[265],"AUC":[269],"0.766":[270],"0.774;":[272],"respectively.":[273],"negatively":[276,320],"fasting":[279],"plasma":[280],"(FPG),":[282],"HBA1c":[283],"each":[285],"period.":[287],"Conclusions:":[288],"Decrease":[289],"most":[295],"sensitive":[296],"specific":[298],"predictor":[299],"incident":[301],"suggesting":[303,325],"is":[307],"involved":[308],"development":[311],"In":[315],"addition,":[316],"strongly":[319],"metabolism,":[324],"intolerance":[327],"lead":[329],"impairment.":[333]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2021-05-10T00:00:00"}