{"id":"https://openalex.org/W3158969415","doi":null,"title":"Dental Adhesive Systems Loaded with Antimicrobial Drug-silica-Co-assembled Particles for Interfacial Biodegradation and Recurrent Caries Reduction","display_name":"Dental Adhesive Systems Loaded with Antimicrobial Drug-silica-Co-assembled Particles for Interfacial Biodegradation and Recurrent Caries Reduction","publication_year":2020,"publication_date":"2020-11-01","ids":{"openalex":"https://openalex.org/W3158969415","mag":"3158969415"},"language":"en","primary_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/103721","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/103721","pdf_url":"https://utoronto.scholaris.ca/bitstreams/e8e44ac5-e119-4433-8a6c-ce256c1835af/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://utoronto.scholaris.ca/bitstreams/e8e44ac5-e119-4433-8a6c-ce256c1835af/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083716060","display_name":"Kimberly Ngai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kimberly Ngai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5083716060"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10113","display_name":"Dental materials and restorations","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10113","display_name":"Dental materials and restorations","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10536","display_name":"Endodontics and Root Canal Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10368","display_name":"Dental Health and Care Utilization","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dental-adhesives","display_name":"dental adhesives","score":0.9340000152587891},{"id":"https://openalex.org/keywords/secondary-caries","display_name":"secondary caries","score":0.9070000052452087},{"id":"https://openalex.org/keywords/composite-resin-restorations","display_name":"composite resin restorations","score":0.9599999785423279},{"id":"https://openalex.org/keywords/cavitation","display_name":"cavitation","score":0.8190000057220459},{"id":"https://openalex.org/keywords/photothermal-radiometry","display_name":"photothermal radiometry","score":0.8429999947547913},{"id":"https://openalex.org/keywords/luminescence","display_name":"luminescence","score":0.847000002861023},{"id":"https://openalex.org/keywords/caries-detection","display_name":"caries detection","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cariogenic-bacteria","display_name":"cariogenic bacteria","score":0.7929999828338623},{"id":"https://openalex.org/keywords/restoration-longevity","display_name":"restoration longevity","score":0.7559999823570251}],"concepts":[{"id":"https://openalex.org/C157021035","wikidata":"https://www.wikidata.org/wiki/Q696715","display_name":"Biodegradation","level":2,"score":0.7580454349517822},{"id":"https://openalex.org/C68928338","wikidata":"https://www.wikidata.org/wiki/Q131790","display_name":"Adhesive","level":3,"score":0.6171109080314636},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.5840237736701965},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4730778634548187},{"id":"https://openalex.org/C111335779","wikidata":"https://www.wikidata.org/wiki/Q3454686","display_name":"Reduction (mathematics)","level":2,"score":0.4697430729866028},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.41357266902923584},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.30153214931488037},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2752073407173157},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1677972972393036},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.11030846834182739},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2779227376","wikidata":"https://www.wikidata.org/wiki/Q6505497","display_name":"Layer (electronics)","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:utoronto.scholaris.ca:1807/103721","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/103721","pdf_url":"https://utoronto.scholaris.ca/bitstreams/e8e44ac5-e119-4433-8a6c-ce256c1835af/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:3158969415","doi":null,"is_oa":false,"landing_page_url":"https://tspace.library.utoronto.ca/bitstream/1807/103721/1/Ngai_Kimberly_202011_MSc_thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/103721","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/103721","pdf_url":"https://utoronto.scholaris.ca/bitstreams/e8e44ac5-e119-4433-8a6c-ce256c1835af/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3219723263","display_name":null,"funder_award_id":"I2IPJ","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"}],"funders":[{"id":"https://openalex.org/F4320308298","display_name":"California HIV/AIDS Research Program","ror":"https://ror.org/00pjdza24"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3158969415.pdf","grobid_xml":"https://content.openalex.org/works/W3158969415.grobid-xml"},"referenced_works_count":120,"referenced_works":["https://openalex.org/W5178588","https://openalex.org/W189992772","https://openalex.org/W206504336","https://openalex.org/W1547768294","https://openalex.org/W1564994625","https://openalex.org/W1576520315","https://openalex.org/W1884852934","https://openalex.org/W1895674416","https://openalex.org/W1916443299","https://openalex.org/W1964682327","https://openalex.org/W1965018428","https://openalex.org/W1965604101","https://openalex.org/W1967102737","https://openalex.org/W1971583779","https://openalex.org/W1975793715","https://openalex.org/W1978180107","https://openalex.org/W1978537488","https://openalex.org/W1981274003","https://openalex.org/W1986365298","https://openalex.org/W1987336642","https://openalex.org/W1989475242","https://openalex.org/W1993281392","https://openalex.org/W1995041236","https://openalex.org/W1995869725","https://openalex.org/W1996006776","https://openalex.org/W1999317855","https://openalex.org/W1999572601","https://openalex.org/W2006369950","https://openalex.org/W2008122663","https://openalex.org/W2009901448","https://openalex.org/W2010730839","https://openalex.org/W2014252364","https://openalex.org/W2019867540","https://openalex.org/W2020754198","https://openalex.org/W2024137597","https://openalex.org/W2028982372","https://openalex.org/W2032861572","https://openalex.org/W2036058330","https://openalex.org/W2036261157","https://openalex.org/W2039347993","https://openalex.org/W2039397068","https://openalex.org/W2040147449","https://openalex.org/W2041567727","https://openalex.org/W2044757734","https://openalex.org/W2047995784","https://openalex.org/W2049280327","https://openalex.org/W2052625988","https://openalex.org/W2053775029","https://openalex.org/W2056949659","https://openalex.org/W2058013401","https://openalex.org/W2058152510","https://openalex.org/W2058241112","https://openalex.org/W2058369588","https://openalex.org/W2059772581","https://openalex.org/W2060266816","https://openalex.org/W2061865707","https://openalex.org/W2064788953","https://openalex.org/W2069494300","https://openalex.org/W2070130634","https://openalex.org/W2070517548","https://openalex.org/W2073997136","https://openalex.org/W2074578380","https://openalex.org/W2080468037","https://openalex.org/W2080502248","https://openalex.org/W2084337627","https://openalex.org/W2089959956","https://openalex.org/W2091059233","https://openalex.org/W2092944594","https://openalex.org/W2097274883","https://openalex.org/W2097312836","https://openalex.org/W2098331318","https://openalex.org/W2099079698","https://openalex.org/W2099557843","https://openalex.org/W2103637866","https://openalex.org/W2103775709","https://openalex.org/W2104572739","https://openalex.org/W2104771379","https://openalex.org/W2105887314","https://openalex.org/W2114047711","https://openalex.org/W2121748291","https://openalex.org/W2123125331","https://openalex.org/W2123791769","https://openalex.org/W2129172530","https://openalex.org/W2130829765","https://openalex.org/W2131359149","https://openalex.org/W2135724989","https://openalex.org/W2136032547","https://openalex.org/W2140617914","https://openalex.org/W2143517063","https://openalex.org/W2144612702","https://openalex.org/W2150226037","https://openalex.org/W2153290403","https://openalex.org/W2158255299","https://openalex.org/W2162963173","https://openalex.org/W2163002007","https://openalex.org/W2167269512","https://openalex.org/W2167879277","https://openalex.org/W2168373863","https://openalex.org/W2168920694","https://openalex.org/W2169178938","https://openalex.org/W2169179419","https://openalex.org/W2170055853","https://openalex.org/W2271290467","https://openalex.org/W2338932213","https://openalex.org/W2410993400","https://openalex.org/W2412698630","https://openalex.org/W2522243242","https://openalex.org/W2525736399","https://openalex.org/W2526367404","https://openalex.org/W2551840051","https://openalex.org/W2558939161","https://openalex.org/W2775014873","https://openalex.org/W2793319096","https://openalex.org/W2797214531","https://openalex.org/W2809991950","https://openalex.org/W2892646383","https://openalex.org/W2894621186","https://openalex.org/W2915859492","https://openalex.org/W3021345445","https://openalex.org/W4230690150"],"related_works":["https://openalex.org/W4413766503","https://openalex.org/W2809991950","https://openalex.org/W2074588907","https://openalex.org/W3102404219","https://openalex.org/W2922752669","https://openalex.org/W7052873876","https://openalex.org/W2804482887","https://openalex.org/W1984819833","https://openalex.org/W2996644317","https://openalex.org/W1965018428"],"abstract_inverted_index":{"Resin":[0],"composite":[1,134],"restorations":[2],"fail":[3],"prematurely":[4],"mainly":[5],"due":[6],"to":[7,13,64,110,121,128],"biodegradation":[8,72,97],"and":[9,30,34,39,61,73,82,85,98,112],"bacterial":[10],"attack,":[11],"leading":[12],"recurrent":[14,49,74,99,145],"caries.":[15,100],"It":[16],"is":[17,124],"hypothesized":[18],"that":[19,88],"1)":[20],"dental":[21,90,122,141],"adhesives":[22,91,123],"containing":[23],"drug-silica-co-assembled-particles":[24],"(DSPs)":[25],"inhibit":[26],"interfacial":[27,32,71,83,96],"bacterial-biodegradation-markers":[28],"(BBMs)":[29],"reduce":[31],"demineralization":[33,84,111],"cavitation;":[35],"2)":[36],"photothermal":[37],"radiometry":[38],"luminescence":[40],"(PTR-LUM)":[41],"technology":[42,102,138],"correlates":[43],"positively":[44,108],"with":[45],"micro-computed-tomography":[46],"(\u00b5CT)":[47],"in":[48,80,94,143],"caries":[50,75],"detection.":[51],"In":[52],"vitro":[53],"models":[54],"based":[55],"on":[56,70],"simulated":[57],"human":[58],"salivary":[59],"esterases":[60],"cariogenic":[62],"bacteria":[63],"evaluate":[65],"the":[66,130],"effects":[67],"of":[68,118,132],"DSPs":[69],"development":[76],"show":[77],"long-term":[78],"reduction":[79],"BBMs":[81],"cavitation,":[86],"suggesting":[87],"DSP-loaded":[89],"are":[92],"efficacious":[93],"reducing":[95],"PTR-LUM":[101,137],"(the":[103],"Canary":[104],"System":[105],"Numbers),":[106],"was":[107],"correlated":[109],"cavitation":[113],"measurements":[114],"by":[115],"\u00b5CT.":[116],"Provision":[117],"antimicrobial-antidegradative":[119],"properties":[120],"a":[125],"promising":[126],"strategy":[127],"improve":[129],"longevity":[131],"resin":[133],"restorations.":[135],"Additionally,":[136],"may":[139],"aid":[140],"professionals":[142],"detecting":[144],"caries,":[146],"without":[147],"radiation":[148],"exposure.":[149]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-05-10T00:00:00"}
