{"id":"https://openalex.org/W3150423484","doi":"https://doi.org/10.5251/abjna.2010.1.3.307.312","title":"Activity of ethanolic extract of Clerodendrum violaceum leaves against Plasmodium berghei in mice","display_name":"Activity of ethanolic extract of Clerodendrum violaceum leaves against Plasmodium berghei in mice","publication_year":2010,"publication_date":"2010-05-01","ids":{"openalex":"https://openalex.org/W3150423484","doi":"https://doi.org/10.5251/abjna.2010.1.3.307.312","mag":"3150423484"},"language":"en","primary_location":{"id":"doi:10.5251/abjna.2010.1.3.307.312","doi":"https://doi.org/10.5251/abjna.2010.1.3.307.312","is_oa":true,"landing_page_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","pdf_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","source":{"id":"https://openalex.org/S89066413","display_name":"Agriculture and Biology Journal of North America","issn_l":"2151-7517","issn":["2151-7517","2151-7525","2151-7533"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4387155642","host_organization_name":"Science Hub","host_organization_lineage":["https://openalex.org/I4387155642"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agriculture and Biology Journal of North America","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112367328","display_name":"E.A. Balogun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"E. Balogun","raw_affiliation_strings":["Department of Biochemistry, University of Ilorin, Ilorin, Kwara State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Ilorin, Ilorin, Kwara State, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069454071","display_name":"Joseph Oluwatope Adebayo","orcid":"https://orcid.org/0000-0003-3151-2247","observed_orcids":["https://orcid.org/0000-0003-3151-2247"]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"J. Adebayo","raw_affiliation_strings":["Department of Biochemistry, University of Ilorin, Ilorin, Kwara State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Ilorin, Ilorin, Kwara State, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093431652","display_name":"Hauwa Ahmed Zailani","orcid":"https://orcid.org/0000-0003-2930-430X","observed_orcids":["https://orcid.org/0000-0003-2930-430X"]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"A. Zailani","raw_affiliation_strings":["Department of Biochemistry, University of Ilorin, Ilorin, Kwara State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Ilorin, Ilorin, Kwara State, Nigeria","institution_ids":["https://openalex.org/I134542131"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047156234","display_name":"Oyetunji Timothy Kolawole","orcid":"https://orcid.org/0000-0001-5721-0883","observed_orcids":["https://orcid.org/0000-0001-5721-0883"]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]},{"id":"https://openalex.org/I2800598127","display_name":"University College Hospital, Ibadan","ror":"https://ror.org/022yvqh08","country_code":"NG","type":"healthcare","lineage":["https://openalex.org/I2800598127"]},{"id":"https://openalex.org/I4405266076","display_name":"Institute for Advanced Medical Research and Training","ror":"https://ror.org/0061ew423","country_code":"NG","type":"facility","lineage":["https://openalex.org/I181631907","https://openalex.org/I4405266076"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O. Kolawole","raw_affiliation_strings":["Department of Microbiology, University of Ilorin, Ilorin, Kwara State, Nigeria","Institute of Advanced Medical Research and Training, University College Hospital, Ibadan, Oyo State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Ilorin, Ilorin, Kwara State, Nigeria","institution_ids":["https://openalex.org/I134542131"]},{"raw_affiliation_string":"Institute of Advanced Medical Research and Training, University College Hospital, Ibadan, Oyo State, Nigeria","institution_ids":["https://openalex.org/I2800598127","https://openalex.org/I4405266076"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082986911","display_name":"Olusegun George Ademowo","orcid":"https://orcid.org/0000-0003-4020-5134","observed_orcids":["https://orcid.org/0000-0003-4020-5134"]},"institutions":[{"id":"https://openalex.org/I134542131","display_name":"University of Ilorin","ror":"https://ror.org/032kdwk38","country_code":"NG","type":"education","lineage":["https://openalex.org/I134542131"]},{"id":"https://openalex.org/I2800598127","display_name":"University College Hospital, Ibadan","ror":"https://ror.org/022yvqh08","country_code":"NG","type":"healthcare","lineage":["https://openalex.org/I2800598127"]},{"id":"https://openalex.org/I4405266076","display_name":"Institute for Advanced Medical Research and Training","ror":"https://ror.org/0061ew423","country_code":"NG","type":"facility","lineage":["https://openalex.org/I181631907","https://openalex.org/I4405266076"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O. Ademowo","raw_affiliation_strings":["Department of Microbiology, University of Ilorin, Ilorin, Kwara State, Nigeria","Institute of Advanced Medical Research and Training, University College Hospital, Ibadan, Oyo State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, University of Ilorin, Ilorin, Kwara State, Nigeria","institution_ids":["https://openalex.org/I134542131"]},{"raw_affiliation_string":"Institute of Advanced Medical Research and Training, University College Hospital, Ibadan, Oyo State, Nigeria","institution_ids":["https://openalex.org/I2800598127","https://openalex.org/I4405266076"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6341,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.73369661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"1","issue":"3","first_page":"307","last_page":"312"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.8955000042915344,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.8955000042915344,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.08449999988079071,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antimalarial-activity","display_name":"antimalarial activity","score":0.8539999723434448},{"id":"https://openalex.org/keywords/plasmodium-berghei","display_name":"Plasmodium berghei","score":0.9890000224113464},{"id":"https://openalex.org/keywords/ethanolic-leaf-extract","display_name":"ethanolic leaf extract","score":0.9160000085830688},{"id":"https://openalex.org/keywords/parasitaemia-suppression","display_name":"parasitaemia suppression","score":0.8949999809265137},{"id":"https://openalex.org/keywords/hematological-parameters","display_name":"hematological parameters","score":0.8769999742507935},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.8529999852180481},{"id":"https://openalex.org/keywords/alkaloids","display_name":"alkaloids","score":0.8790000081062317},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.8429999947547913},{"id":"https://openalex.org/keywords/red-blood-cell-count","display_name":"red blood cell count","score":0.6840000152587891},{"id":"https://openalex.org/keywords/white-blood-cell-count","display_name":"white blood cell count","score":0.8679999709129333},{"id":"https://openalex.org/keywords/platelet-count","display_name":"platelet count","score":0.9459999799728394},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.47699999809265137}],"concepts":[{"id":"https://openalex.org/C2777237215","wikidata":"https://www.wikidata.org/wiki/Q65021","display_name":"Plasmodium berghei","level":3,"score":0.9640913009643555},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.865035891532898},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5285971164703369},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.37048959732055664},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.3620968759059906},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11699730157852173},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.046499013900756836}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5251/abjna.2010.1.3.307.312","doi":"https://doi.org/10.5251/abjna.2010.1.3.307.312","is_oa":true,"landing_page_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","pdf_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","source":{"id":"https://openalex.org/S89066413","display_name":"Agriculture and Biology Journal of North America","issn_l":"2151-7517","issn":["2151-7517","2151-7525","2151-7533"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4387155642","host_organization_name":"Science Hub","host_organization_lineage":["https://openalex.org/I4387155642"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agriculture and Biology Journal of North America","raw_type":"journal-article"},{"id":"mag:2038153193","doi":null,"is_oa":false,"landing_page_url":"http://scihub.org/ABJNA/PDF/2010/3/1-3-307-312.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.5251/abjna.2010.1.3.307.312","doi":"https://doi.org/10.5251/abjna.2010.1.3.307.312","is_oa":true,"landing_page_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","pdf_url":"https://doi.org/10.5251/abjna.2010.1.3.307.312","source":{"id":"https://openalex.org/S89066413","display_name":"Agriculture and Biology Journal of North America","issn_l":"2151-7517","issn":["2151-7517","2151-7525","2151-7533"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4387155642","host_organization_name":"Science Hub","host_organization_lineage":["https://openalex.org/I4387155642"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Agriculture and Biology Journal of North America","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3150423484.pdf","grobid_xml":"https://content.openalex.org/works/W3150423484.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W158489181","https://openalex.org/W1538764270","https://openalex.org/W1558598870","https://openalex.org/W1986200639","https://openalex.org/W2014862126","https://openalex.org/W2048720928","https://openalex.org/W2067428749","https://openalex.org/W2072280620","https://openalex.org/W2122849872","https://openalex.org/W2169304723","https://openalex.org/W2256248620","https://openalex.org/W2321413400","https://openalex.org/W2330183474","https://openalex.org/W2424930075","https://openalex.org/W2742445911","https://openalex.org/W2955504961","https://openalex.org/W4300187878"],"related_works":["https://openalex.org/W4400083995","https://openalex.org/W2902767160","https://openalex.org/W4362608544","https://openalex.org/W7216832192","https://openalex.org/W2980792248","https://openalex.org/W7105507812","https://openalex.org/W274658466","https://openalex.org/W1981268225","https://openalex.org/W7220593648","https://openalex.org/W1969528234"],"abstract_inverted_index":{"The":[0],"antimalarial":[1,116,143],"potential":[2],"of":[3,7,53,122,142],"the":[4,25,30,62,105,112],"ethanolic":[5],"extract":[6,64,113],"Clerodendrum":[8,136],"violaceum":[9,137],"leaves":[10],"(13":[11],"mg/kg":[12],"body":[13],"weight)":[14],"was":[15],"investigated":[16],"in":[17,61],"mice":[18,71],"infected":[19,70,78,106],"with":[20],"Plasmodium":[21],"berghei.Haematological":[22],"indices":[23,34],"including":[24],"red":[26,123],"blood":[27,32,85,97,124,127],"cell":[28,33,86,90,98],"indices,":[29],"white":[31,96,126],"and":[35,45,57,101,118,129],"platelet":[36,102],"count":[37,87,99,103],"were":[38],"also":[39],"evaluated":[40],"on":[41,74,135],"days":[42],"3,":[43],"8":[44],"14":[46,76],"after":[47],"infection.Phytochemical":[48],"screening":[49],"revealed":[50],"a":[51,140],"predominance":[52],"alkaloids":[54],"(3.68":[55],"%),":[56],"phenolics":[58],"(2.78":[59],"%)":[60],"extract.The":[63],"suppressed":[65],"parasitaemia":[66],"following":[67],"administration":[68],"to":[69],"by":[72],"92.3%":[73],"day":[75],"post-infection.The":[77],"extracttreated":[79],"animals":[80],"had":[81],"significantly":[82],"higher":[83],"(P<0.05)red":[84],"(RBC),":[88],"packed":[89],"volume":[91],"(PCV),":[92],"haemoglobin":[93],"concentration":[94],"(Hb),":[95],"(WBC),":[100],"than":[104],"untreated":[107],"animals.The":[108],"results":[109,131],"suggest":[110],"that":[111],"possesses":[114],"considerable":[115],"activity":[117],"may":[119],"induce":[120],"synthesis":[121],"cells,":[125],"cells":[128],"platelets.These":[130],"support":[132],"further":[133],"studies":[134],"leaf":[138],"as":[139],"source":[141],"remedy.":[144]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-04-13T00:00:00"}