{"id":"https://openalex.org/W3148926050","doi":null,"title":"Neurogenesis-mediated Forgetting in Morris Water Maze","display_name":"Neurogenesis-mediated Forgetting in Morris Water Maze","publication_year":2020,"publication_date":"2020-11-01","ids":{"openalex":"https://openalex.org/W3148926050","mag":"3148926050"},"language":"en","primary_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/103178","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/103178","pdf_url":"https://utoronto.scholaris.ca/bitstreams/f8a8f743-e118-4e12-8099-3126dd8f2c94/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://utoronto.scholaris.ca/bitstreams/f8a8f743-e118-4e12-8099-3126dd8f2c94/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079135168","display_name":"Chunan Duan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Chunan Duan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079135168"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.6464999914169312,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.6464999914169312,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.35109999775886536,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10918","display_name":"Memory Processes and Influences","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adult-neurogenesis","display_name":"adult neurogenesis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/forgetting","display_name":"forgetting","score":0.7179999947547913},{"id":"https://openalex.org/keywords/hippocampus-dependent-memory","display_name":"hippocampal-dependent memory","score":0.8460000157356262},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.9419999718666077},{"id":"https://openalex.org/keywords/morris-water-maze","display_name":"Morris water maze","score":0.9509999752044678},{"id":"https://openalex.org/keywords/memory-precision","display_name":"memory precision","score":0.925000011920929},{"id":"https://openalex.org/keywords/memory-generalization","display_name":"memory generalization","score":0.9350000023841858},{"id":"https://openalex.org/keywords/neonatal-mice","display_name":"neonatal mice","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.9509433507919312},{"id":"https://openalex.org/C44752575","wikidata":"https://www.wikidata.org/wiki/Q1417562","display_name":"Morris water navigation task","level":3,"score":0.8867462277412415},{"id":"https://openalex.org/C7149132","wikidata":"https://www.wikidata.org/wiki/Q1377840","display_name":"Forgetting","level":2,"score":0.8142363429069519},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.6717736721038818},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5453746318817139},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.531446635723114},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.20410984754562378}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:utoronto.scholaris.ca:1807/103178","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/103178","pdf_url":"https://utoronto.scholaris.ca/bitstreams/f8a8f743-e118-4e12-8099-3126dd8f2c94/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:3148926050","doi":null,"is_oa":false,"landing_page_url":"https://tspace.library.utoronto.ca/bitstream/1807/103178/3/Duan_Chunan_202011_MSc_thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:utoronto.scholaris.ca:1807/103178","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1807/103178","pdf_url":"https://utoronto.scholaris.ca/bitstreams/f8a8f743-e118-4e12-8099-3126dd8f2c94/download","source":{"id":"https://openalex.org/S4306400261","display_name":"TSpace (University of Toronto)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I185261750","host_organization_name":"University of Toronto","host_organization_lineage":["https://openalex.org/I185261750"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.46810001134872437,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3148926050.pdf","grobid_xml":"https://content.openalex.org/works/W3148926050.grobid-xml"},"referenced_works_count":119,"referenced_works":["https://openalex.org/W1571505505","https://openalex.org/W1581458838","https://openalex.org/W1591199750","https://openalex.org/W1608785134","https://openalex.org/W1920095995","https://openalex.org/W1957947226","https://openalex.org/W1964919587","https://openalex.org/W1965011547","https://openalex.org/W1965219739","https://openalex.org/W1966555773","https://openalex.org/W1967216683","https://openalex.org/W1968840425","https://openalex.org/W1971353156","https://openalex.org/W1974225650","https://openalex.org/W1974491267","https://openalex.org/W1978474530","https://openalex.org/W1980499453","https://openalex.org/W1981279518","https://openalex.org/W1982528484","https://openalex.org/W1988633143","https://openalex.org/W1989049076","https://openalex.org/W1993476794","https://openalex.org/W1993725941","https://openalex.org/W1994580609","https://openalex.org/W1994750275","https://openalex.org/W1995188451","https://openalex.org/W1996847178","https://openalex.org/W1997071197","https://openalex.org/W2000145003","https://openalex.org/W2000214310","https://openalex.org/W2002648857","https://openalex.org/W2003716471","https://openalex.org/W2006629692","https://openalex.org/W2007095775","https://openalex.org/W2007316548","https://openalex.org/W2011761743","https://openalex.org/W2014443309","https://openalex.org/W2015629132","https://openalex.org/W2017169966","https://openalex.org/W2018344355","https://openalex.org/W2019971749","https://openalex.org/W2022372660","https://openalex.org/W2023147143","https://openalex.org/W2028316770","https://openalex.org/W2032958507","https://openalex.org/W2037594700","https://openalex.org/W2041104744","https://openalex.org/W2046598368","https://openalex.org/W2047535883","https://openalex.org/W2047891649","https://openalex.org/W2051173215","https://openalex.org/W2052439938","https://openalex.org/W2052515926","https://openalex.org/W2053127475","https://openalex.org/W2055503718","https://openalex.org/W2055887456","https://openalex.org/W2057143757","https://openalex.org/W2057608998","https://openalex.org/W2059148040","https://openalex.org/W2059471650","https://openalex.org/W2061111257","https://openalex.org/W2063466545","https://openalex.org/W2064982132","https://openalex.org/W2066170543","https://openalex.org/W2067856703","https://openalex.org/W2070358533","https://openalex.org/W2083194463","https://openalex.org/W2085417640","https://openalex.org/W2086789511","https://openalex.org/W2086842760","https://openalex.org/W2088024567","https://openalex.org/W2091997230","https://openalex.org/W2092499931","https://openalex.org/W2097723313","https://openalex.org/W2102912401","https://openalex.org/W2108455695","https://openalex.org/W2111354960","https://openalex.org/W2111977586","https://openalex.org/W2117107695","https://openalex.org/W2119424745","https://openalex.org/W2120666926","https://openalex.org/W2120811265","https://openalex.org/W2124190705","https://openalex.org/W2124529404","https://openalex.org/W2125095601","https://openalex.org/W2129295534","https://openalex.org/W2130169724","https://openalex.org/W2134145060","https://openalex.org/W2145077203","https://openalex.org/W2146316688","https://openalex.org/W2147922810","https://openalex.org/W2148239264","https://openalex.org/W2155505956","https://openalex.org/W2156701948","https://openalex.org/W2160071886","https://openalex.org/W2161446495","https://openalex.org/W2169473035","https://openalex.org/W2171623935","https://openalex.org/W2304552143","https://openalex.org/W2499054763","https://openalex.org/W2505391536","https://openalex.org/W2524675301","https://openalex.org/W2561813954","https://openalex.org/W2722019070","https://openalex.org/W2786519344","https://openalex.org/W2788823474","https://openalex.org/W2796418566","https://openalex.org/W2809119452","https://openalex.org/W2811270075","https://openalex.org/W2825664474","https://openalex.org/W2888160649","https://openalex.org/W2905430542","https://openalex.org/W2947740526","https://openalex.org/W2965256549","https://openalex.org/W2967925629","https://openalex.org/W2971170460","https://openalex.org/W3036638316","https://openalex.org/W3041214984","https://openalex.org/W4249412541"],"related_works":["https://openalex.org/W3174152040","https://openalex.org/W2769599126","https://openalex.org/W2130169724","https://openalex.org/W2136210766","https://openalex.org/W6910935659","https://openalex.org/W2015098736","https://openalex.org/W2037054525","https://openalex.org/W3138104264","https://openalex.org/W7095074622","https://openalex.org/W7097740696"],"abstract_inverted_index":{"Neurogenesis,":[0],"the":[1,7,44,50,67,81,108,119],"generation":[2],"of":[3,18,40,110,129],"new":[4],"neurons":[5],"in":[6,21,35,43,64,80,89,103,133],"hippocampus,":[8],"has":[9],"been":[10],"identified":[11],"as":[12],"an":[13],"underlying":[14],"mechanism":[15],"for":[16,57],"forgetting":[17,34,63,100],"hippocampus-dependent":[19],"memories":[20],"adult":[22,91],"and":[23,92],"infant":[24,93],"mice.":[25,94],"However,":[26],"a":[27],"recent":[28],"study":[29,52],"failed":[30],"to":[31,54],"replicate":[32],"neurogenesis-mediated":[33,62,99],"rats":[36],"using":[37,66],"multiple":[38,86],"measures":[39,88,105,115],"spatial":[41],"memory":[42,111,120,130,134],"Morris":[45,68,82],"water":[46,69,83],"maze":[47,70,84],"paradigm.":[48,71],"Thus,":[49],"current":[51],"aims":[53],"explore":[55],"explanations":[56],"this":[58],"discrepancy":[59],"by":[60],"investigating":[61],"mice":[65],"I":[72,122],"analyzed":[73],"behavioral":[74,104],"changes":[75],"associated":[76],"with":[77,85],"increased":[78],"neurogenesis":[79],"quantitative":[87],"both":[90],"My":[95],"results":[96,132],"showed":[97],"that":[98,106,116,126],"is":[101],"reflected":[102],"capture":[107,118],"loss":[109,128],"precision,":[112],"but":[113],"not":[114],"only":[117],"gist.":[121],"also":[123],"found":[124],"evidence":[125],"neurogenesis-associated":[127],"precision":[131],"generalization.":[135]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2021-04-13T00:00:00"}
