{"id":"https://openalex.org/W3147953630","doi":"https://doi.org/10.1111/apt.12517","title":"Commentary: the effects of probiotics on barrier function and mucosal pouch microbiota during maintenance treatment for severe pouchitis in patients with ulcerative colitis","display_name":"Commentary: the effects of probiotics on barrier function and mucosal pouch microbiota during maintenance treatment for severe pouchitis in patients with ulcerative colitis","publication_year":2013,"publication_date":"2013-11-10","ids":{"openalex":"https://openalex.org/W3147953630","doi":"https://doi.org/10.1111/apt.12517","mag":"3147953630","pmid":"https://pubmed.ncbi.nlm.nih.gov/24206372"},"language":"en","primary_location":{"id":"doi:10.1111/apt.12517","doi":"https://doi.org/10.1111/apt.12517","is_oa":true,"landing_page_url":"https://doi.org/10.1111/apt.12517","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apt.12517","source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology & Therapeutics","raw_type":"journal-article"},"volume":null,"type":"editorial","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apt.12517","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111626023","display_name":"Jon Landy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Landy","raw_affiliation_strings":["IBD Unit, St Mark's Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IBD Unit, St Mark's Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040981628","display_name":"Ailsa L Hart","orcid":"https://orcid.org/0000-0002-7141-6076","observed_orcids":["https://orcid.org/0000-0002-7141-6076"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"A. Hart","raw_affiliation_strings":["IBD Unit, St Mark's Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IBD Unit, St Mark's Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210161740"],"apc_list":{"value":5250,"currency":"USD","value_usd":5250},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":"11-12","first_page":"1405","last_page":"1406"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.7993000149726868,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.7993000149726868,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.18119999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.006300000008195639,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":1.0},{"id":"https://openalex.org/keywords/pouchitis","display_name":"pouchitis","score":0.8960000276565552},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.9739999771118164},{"id":"https://openalex.org/keywords/mucosal-barrier-function","display_name":"mucosal barrier function","score":0.7319999933242798},{"id":"https://openalex.org/keywords/maintenance-therapy","display_name":"maintenance therapy","score":0.6830000281333923},{"id":"https://openalex.org/keywords/ileal-pouch-anal-anastomosis","display_name":"ileal pouch-anal anastomosis","score":0.8420000076293945}],"concepts":[{"id":"https://openalex.org/C2779454807","wikidata":"https://www.wikidata.org/wiki/Q3392956","display_name":"Pouchitis","level":4,"score":0.9925115704536438},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.8566428422927856},{"id":"https://openalex.org/C51911345","wikidata":"https://www.wikidata.org/wiki/Q4863604","display_name":"Barrier function","level":2,"score":0.7984126806259155},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7192663550376892},{"id":"https://openalex.org/C2780101441","wikidata":"https://www.wikidata.org/wiki/Q949930","display_name":"Pouch","level":2,"score":0.6264526844024658},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.566650927066803},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.561227023601532},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5432743430137634},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.48441675305366516},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.466599702835083},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.4552825689315796},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4510788023471832},{"id":"https://openalex.org/C2775862500","wikidata":"https://www.wikidata.org/wiki/Q2453464","display_name":"Colitis","level":2,"score":0.44410163164138794},{"id":"https://openalex.org/C3019368612","wikidata":"https://www.wikidata.org/wiki/Q17154506","display_name":"Intestinal mucosa","level":2,"score":0.4190453588962555},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.29563844203948975},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.13513174653053284},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1275748908519745},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.082161545753479},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019449","descriptor_name":"Pouchitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D039021","descriptor_name":"Colonic Pouches","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/apt.12517","doi":"https://doi.org/10.1111/apt.12517","is_oa":true,"landing_page_url":"https://doi.org/10.1111/apt.12517","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apt.12517","source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology & Therapeutics","raw_type":"journal-article"},{"id":"pmid:24206372","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24206372","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary pharmacology & therapeutics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/apt.12517","doi":"https://doi.org/10.1111/apt.12517","is_oa":true,"landing_page_url":"https://doi.org/10.1111/apt.12517","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/apt.12517","source":{"id":"https://openalex.org/S158079644","display_name":"Alimentary Pharmacology & Therapeutics","issn_l":"0269-2813","issn":["0269-2813","1365-2036"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alimentary Pharmacology & Therapeutics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306169","display_name":"Eli and Edythe Broad Foundation","ror":"https://ror.org/03atssj74"},{"id":"https://openalex.org/F4320320283","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3147953630.pdf","grobid_xml":"https://content.openalex.org/works/W3147953630.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1972441174","https://openalex.org/W1977475121","https://openalex.org/W1978345442","https://openalex.org/W1996322967","https://openalex.org/W2012138234","https://openalex.org/W2055847901","https://openalex.org/W2063157334","https://openalex.org/W2077198680","https://openalex.org/W2091250795","https://openalex.org/W2139387284","https://openalex.org/W2153551892","https://openalex.org/W2155703794"],"related_works":["https://openalex.org/W2063695135","https://openalex.org/W1978345442","https://openalex.org/W1594316124","https://openalex.org/W2076694193","https://openalex.org/W4405782265","https://openalex.org/W2569525025","https://openalex.org/W2362656620","https://openalex.org/W2586737108","https://openalex.org/W1998690031","https://openalex.org/W2266342022"],"abstract_inverted_index":{"Commentary:":[0],"the":[1],"effects":[2],"of":[3],"probiotics":[4]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-04-13T00:00:00"}