{"id":"https://openalex.org/W3147811369","doi":null,"title":"PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION","display_name":"PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W3147811369","mag":"3147811369"},"language":"en","primary_location":{"id":"mag:3147811369","doi":null,"is_oa":false,"landing_page_url":"https://asecho.org/wordpress/wp-content/uploads/2014/09/21-2002-N-Engl-J-Med-2002-Prophylactic-Implantation-of-a-Defibrillator-in-Patients-with-Myocardial-Infarction.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003321226","display_name":"J. M Oss","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. M Oss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051571038","display_name":"W Ojciech Z Areba","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Ojciech Z Areba","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032022652","display_name":"W. J Ackson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. J Ackson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048793813","display_name":"H Elmut K Lein","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Elmut K Lein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091714686","display_name":"D Avid J. W Ilber","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Avid J. W Ilber","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026312401","display_name":"D Avid S. C Annom","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Avid S. C Annom","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jennifer M. Ames","orcid":"https://orcid.org/0000-0003-2327-6416","observed_orcids":["https://orcid.org/0000-0003-2327-6416"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer M. Ames","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2327-6416","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"P Aubert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Aubert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040824432","display_name":"S Teven L. H Iggins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Teven L. H Iggins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090797619","display_name":"M Ary W. B Rown","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Ary W. B Rown","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5023780412","display_name":"M Ark L. A Ndrews","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Ark L. A Ndrews","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":88.1751,"has_fulltext":false,"cited_by_count":2027,"citation_normalized_percentile":{"value":0.99958809,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/implantable-cardioverter-defibrillator","display_name":"implantable cardioverter-defibrillator","score":0.9879999756813049},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9929999709129333},{"id":"https://openalex.org/keywords/reduced-left-ventricular-ejection-fraction","display_name":"reduced left ventricular ejection fraction","score":0.9399999976158142},{"id":"https://openalex.org/keywords/left-ventricular-dysfunction","display_name":"left ventricular dysfunction","score":0.8370000123977661},{"id":"https://openalex.org/keywords/ventricular-arrhythmias","display_name":"ventricular arrhythmias","score":0.8619999885559082},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5759999752044678},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.8479999899864197},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.5659999847412109},{"id":"https://openalex.org/keywords/qrs-duration","display_name":"QRS duration","score":0.5249999761581421}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9175636768341064},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.795893669128418},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7415094971656799},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7247248888015747},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7122902274131775},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6822938919067383},{"id":"https://openalex.org/C111773187","wikidata":"https://www.wikidata.org/wiki/Q1969239","display_name":"QRS complex","level":2,"score":0.5719811916351318},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5075472593307495},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.476073682308197},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.38411521911621094},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.38163089752197266}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:3147811369","doi":null,"is_oa":false,"landing_page_url":"https://asecho.org/wordpress/wp-content/uploads/2014/09/21-2002-N-Engl-J-Med-2002-Prophylactic-Implantation-of-a-Defibrillator-in-Patients-with-Myocardial-Infarction.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1580788756","https://openalex.org/W1968713194","https://openalex.org/W1972210312","https://openalex.org/W1974332070","https://openalex.org/W1979300931","https://openalex.org/W2022274686","https://openalex.org/W2039456695","https://openalex.org/W2099090406","https://openalex.org/W2171402333","https://openalex.org/W2313547185","https://openalex.org/W2320382602","https://openalex.org/W2341968681"],"related_works":["https://openalex.org/W3167322928","https://openalex.org/W1984734381","https://openalex.org/W2022554520","https://openalex.org/W2489106637","https://openalex.org/W2028481168","https://openalex.org/W2320382602","https://openalex.org/W2411452357","https://openalex.org/W1533392926","https://openalex.org/W2080894065","https://openalex.org/W2109205604"],"abstract_inverted_index":{"A":[0],"BSTRACT":[1],"Background":[2],"Patients":[3,63],"with":[4,48,170,215],"reduced":[5],"left":[6,55,222],"ventricular":[7,17,56,223],"function":[8],"after":[9],"myocardial":[10,51,218],"infarction":[11,52,219],"are":[12],"at":[13,105,114],"risk":[14,88,158],"for":[15,87,156],"lifethreatening":[16],"arrhythmias.":[18],"This":[19],"randomized":[20],"trial":[21],"was":[22,90,97,174,191],"designed":[23],"to":[24,71,181,198],"evaluate":[25],"the":[26,39,98,109,115,118,125,136,143,150,157,165,171,209],"effect":[27,185],"of":[28,41,59,111,117,133,159,186,227],"an":[29,73,130],"implantable":[30,74],"defibrillator":[31,75,151,166,187,229],"on":[32,189],"survival":[33,190,231],"in":[34,67,124,142,149,164,193],"such":[35],"patients.":[36],"Methods":[37],"Over":[38],"course":[40],"four":[42],"years,":[43],"we":[44],"enrolled":[45],"1232":[46],"patients":[47,214],"a":[49,54,68,216,228,237],"prior":[50,217],"and":[53,108,146,208,220,232],"ejection":[57,201],"fraction":[58],"0.30":[60],"or":[61,78],"less.":[62],"were":[64,122,139],"randomly":[65],"assigned":[66],"3:2":[69],"ratio":[70,155],"receive":[72],"(742":[76],"patients)":[77],"conventional":[79],"medical":[80],"therapy":[81,188],"(490":[82],"patients).":[83],"Invasive":[84],"electrophysiological":[85],"testing":[86],"stratification":[89],"not":[91],"required.":[92],"Death":[93],"from":[94,161],"any":[95,162],"cause":[96,163],"end":[99],"point.":[100],"Results":[101],"The":[102,153,184],"clinical":[103],"characteristics":[104],"base":[106],"line":[107],"prevalence":[110],"medication":[112],"use":[113],"time":[116],"last":[119],"follow-up":[120,132],"visit":[121],"similar":[123,192],"two":[126],"treatment":[127],"groups.":[128],"During":[129],"average":[131],"20":[134],"months,":[135],"mortality":[137],"rates":[138],"19.8":[140],"percent":[141,148,177],"conventional-therapy":[144,172],"group":[145,167,173],"14.2":[147],"group.":[152],"hazard":[154],"death":[160],"as":[168,236],"compared":[169],"0.69":[175],"(95":[176],"confidence":[178],"interval,":[179],"0.51":[180],"0.93;":[182],"P=0.016).":[183],"subgroup":[194],"analyses":[195],"stratified":[196],"according":[197],"age,":[199],"sex,":[200],"fraction,":[202],"New":[203],"York":[204],"Heart":[205],"Association":[206],"class,":[207],"QRS":[210],"interval.":[211],"Conclusions":[212],"In":[213],"advanced":[221],"dysfunction,":[224],"prophylactic":[225],"implantation":[226],"improves":[230],"should":[233],"be":[234],"considered":[235],"recommended":[238],"therapy.":[239],"(N":[240],"Engl":[241],"J":[242],"Med":[243],"2002;346:877-83.)":[244]},"counts_by_year":[{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":73},{"year":2016,"cited_by_count":78},{"year":2015,"cited_by_count":94},{"year":2014,"cited_by_count":75},{"year":2013,"cited_by_count":89},{"year":2012,"cited_by_count":103}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-04-13T00:00:00"}