{"id":"https://openalex.org/W3146400530","doi":"https://doi.org/10.3390/pharmaceutics13040455","title":"An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery","display_name":"An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery","publication_year":2021,"publication_date":"2021-03-27","ids":{"openalex":"https://openalex.org/W3146400530","doi":"https://doi.org/10.3390/pharmaceutics13040455","mag":"3146400530","pmid":"https://pubmed.ncbi.nlm.nih.gov/33801614","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8066039"},"language":"en","primary_location":{"id":"doi:10.3390/pharmaceutics13040455","doi":"https://doi.org/10.3390/pharmaceutics13040455","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics13040455","pdf_url":"https://www.mdpi.com/1999-4923/13/4/455/pdf?version=1617937317","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1999-4923/13/4/455/pdf?version=1617937317","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014749210","display_name":"Kailash C. Petkar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799351866","display_name":"Government of India","ror":"https://ror.org/036h6g940","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866"]},{"id":"https://openalex.org/I4210134808","display_name":"Ministry of Science and Technology","ror":"https://ror.org/03emtbt60","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808"]},{"id":"https://openalex.org/I4210153020","display_name":"Department of Scientific and Industrial Research","ror":"https://ror.org/049nrz535","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I4210153020"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Kailash C. Petkar","raw_affiliation_strings":["Department of Scientific and Industrial Research, Ministry of Science & Technology, Government of India, New Delhi 110016, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Scientific and Industrial Research, Ministry of Science & Technology, Government of India, New Delhi 110016, India","institution_ids":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I4210153020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091394609","display_name":"Suyash M. Patil","orcid":"https://orcid.org/0000-0001-6644-1069","observed_orcids":["https://orcid.org/0000-0001-6644-1069"]},"institutions":[{"id":"https://openalex.org/I142823887","display_name":"St. John's University","ror":"https://ror.org/00bgtad15","country_code":"US","type":"education","lineage":["https://openalex.org/I142823887"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suyash M. Patil","raw_affiliation_strings":["Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John\u2019s University, Jamaica, NY 11439, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John\u2019s University, Jamaica, NY 11439, USA","institution_ids":["https://openalex.org/I142823887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064589151","display_name":"Sandip S. Chavhan","orcid":"https://orcid.org/0000-0003-0536-1027","observed_orcids":["https://orcid.org/0000-0003-0536-1027"]},"institutions":[{"id":"https://openalex.org/I110116418","display_name":"Maharaja Sayajirao University of Baroda","ror":"https://ror.org/01bx8ja67","country_code":"IN","type":"education","lineage":["https://openalex.org/I110116418"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sandip S. Chavhan","raw_affiliation_strings":["Department of Pharmaceutics, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara 390001, India"],"raw_orcid":"https://orcid.org/0000-0003-0536-1027","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara 390001, India","institution_ids":["https://openalex.org/I110116418"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043570415","display_name":"Kan Kaneko","orcid":"https://orcid.org/0000-0001-6838-5195","observed_orcids":["https://orcid.org/0000-0001-6838-5195"]},"institutions":[{"id":"https://openalex.org/I63098007","display_name":"Liverpool John Moores University","ror":"https://ror.org/04zfme737","country_code":"GB","type":"education","lineage":["https://openalex.org/I63098007"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kan Kaneko","raw_affiliation_strings":["School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK","institution_ids":["https://openalex.org/I63098007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033664956","display_name":"Krutika Khanderao Sawant","orcid":"https://orcid.org/0000-0002-7716-2759","observed_orcids":["https://orcid.org/0000-0002-7716-2759"]},"institutions":[{"id":"https://openalex.org/I110116418","display_name":"Maharaja Sayajirao University of Baroda","ror":"https://ror.org/01bx8ja67","country_code":"IN","type":"education","lineage":["https://openalex.org/I110116418"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Krutika K. Sawant","raw_affiliation_strings":["Department of Pharmaceutics, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara 390001, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara 390001, India","institution_ids":["https://openalex.org/I110116418"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086283138","display_name":"Nitesh K. Kunda","orcid":"https://orcid.org/0000-0002-3063-0375","observed_orcids":["https://orcid.org/0000-0002-3063-0375"]},"institutions":[{"id":"https://openalex.org/I142823887","display_name":"St. John's University","ror":"https://ror.org/00bgtad15","country_code":"US","type":"education","lineage":["https://openalex.org/I142823887"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Nitesh K. Kunda","raw_affiliation_strings":["Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John\u2019s University, Jamaica, NY 11439, USA"],"raw_orcid":"https://orcid.org/0000-0002-3063-0375","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John\u2019s University, Jamaica, NY 11439, USA","institution_ids":["https://openalex.org/I142823887"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058060165","display_name":"Imran Y. Saleem","orcid":"https://orcid.org/0000-0003-2382-6668","observed_orcids":["https://orcid.org/0000-0003-2382-6668"]},"institutions":[{"id":"https://openalex.org/I63098007","display_name":"Liverpool John Moores University","ror":"https://ror.org/04zfme737","country_code":"GB","type":"education","lineage":["https://openalex.org/I63098007"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Imran Y. Saleem","raw_affiliation_strings":["School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK"],"raw_orcid":"https://orcid.org/0000-0003-2382-6668","affiliations":[{"raw_affiliation_string":"School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK","institution_ids":["https://openalex.org/I63098007"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5014749210","https://openalex.org/A5058060165","https://openalex.org/A5086283138"],"corresponding_institution_ids":["https://openalex.org/I142823887","https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I4210153020","https://openalex.org/I63098007"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2376},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2376},"fwci":1.931,"has_fulltext":true,"cited_by_count":105,"citation_normalized_percentile":{"value":0.89261234,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"13","issue":"4","first_page":"455","last_page":"455"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.8481000065803528,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.8481000065803528,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.061500001698732376,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.05040000006556511,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vaccine-adjuvants","display_name":"vaccine adjuvants","score":0.902999997138977},{"id":"https://openalex.org/keywords/nanocarriers","display_name":"nanocarriers","score":0.9760000109672546},{"id":"https://openalex.org/keywords/vaccine-delivery","display_name":"vaccine delivery","score":0.8399999737739563},{"id":"https://openalex.org/keywords/viral-vectors","display_name":"viral vectors","score":0.7360000014305115},{"id":"https://openalex.org/keywords/virus-like-particles","display_name":"virus-like particles","score":0.9950000047683716},{"id":"https://openalex.org/keywords/virosomes","display_name":"virosomes","score":1.0},{"id":"https://openalex.org/keywords/nanoemulsions","display_name":"nanoemulsions","score":0.9869999885559082},{"id":"https://openalex.org/keywords/lipid-nanoparticles","display_name":"lipid nanoparticles","score":0.875},{"id":"https://openalex.org/keywords/calcium-phosphate-nanoparticles","display_name":"calcium phosphate nanoparticles","score":0.9430000185966492},{"id":"https://openalex.org/keywords/pattern-recognition-receptors","display_name":"pattern recognition receptors","score":0.890999972820282},{"id":"https://openalex.org/keywords/toll-like-receptors","display_name":"Toll-like receptors","score":0.9179999828338623},{"id":"https://openalex.org/keywords/c-type-lectin-receptors","display_name":"C-type lectin receptors","score":0.8880000114440918},{"id":"https://openalex.org/keywords/sustained-antigen-release","display_name":"sustained antigen release","score":0.8510000109672546},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.5429999828338623}],"concepts":[{"id":"https://openalex.org/C18150654","wikidata":"https://www.wikidata.org/wiki/Q17153796","display_name":"Nanocarriers","level":3,"score":0.92058265209198},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6432850956916809},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.5545192360877991},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.5130466222763062},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4612305462360382},{"id":"https://openalex.org/C111289621","wikidata":"https://www.wikidata.org/wiki/Q418772","display_name":"Pattern recognition receptor","level":4,"score":0.4370802640914917},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34039783477783203},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.32645049691200256},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.32078349590301514},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3201519548892975},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3051379323005676},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.2607007324695587},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.14740383625030518}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/pharmaceutics13040455","doi":"https://doi.org/10.3390/pharmaceutics13040455","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics13040455","pdf_url":"https://www.mdpi.com/1999-4923/13/4/455/pdf?version=1617937317","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},{"id":"pmid:33801614","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33801614","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8066039","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8066039/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"Text"},{"id":"pmh:oai:researchonline.ljmu.ac.uk:14712","doi":null,"is_oa":true,"landing_page_url":"https://researchonline.ljmu.ac.uk/id/eprint/14712/1/pharmaceutics-13-00455.pdf","pdf_url":"https://researchonline.ljmu.ac.uk/id/eprint/14712/1/pharmaceutics-13-00455.pdf","source":{"id":"https://openalex.org/S4306401246","display_name":"Liverpool John Moores University","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I63098007","host_organization_name":"Liverpool John Moores University","host_organization_lineage":["https://openalex.org/I63098007"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:8a495aaa7406414f8d3919af7c2c3fc5","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/8a495aaa7406414f8d3919af7c2c3fc5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceutics, Vol 13, Iss 4, p 455 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/pharmaceutics13040455","doi":"https://doi.org/10.3390/pharmaceutics13040455","is_oa":true,"landing_page_url":"https://doi.org/10.3390/pharmaceutics13040455","pdf_url":"https://www.mdpi.com/1999-4923/13/4/455/pdf?version=1617937317","source":{"id":"https://openalex.org/S30283931","display_name":"Pharmaceutics","issn_l":"1999-4923","issn":["1999-4923"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceutics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5305538399","display_name":"MICA VACCINE FAPESP MICA: Pulmonary Delivery of a Targeted Mucosal Nanocarrier Vaccine for Pneumonia","funder_award_id":"MR/P022758/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3146400530.pdf","grobid_xml":"https://content.openalex.org/works/W3146400530.grobid-xml"},"referenced_works_count":172,"referenced_works":["https://openalex.org/W63612215","https://openalex.org/W1503083731","https://openalex.org/W1514540900","https://openalex.org/W1531317003","https://openalex.org/W1567847444","https://openalex.org/W1574479676","https://openalex.org/W1576543020","https://openalex.org/W1604712861","https://openalex.org/W1712882243","https://openalex.org/W1839141223","https://openalex.org/W1965967273","https://openalex.org/W1967110055","https://openalex.org/W1969641931","https://openalex.org/W1971903986","https://openalex.org/W1972230556","https://openalex.org/W1973905472","https://openalex.org/W1994399275","https://openalex.org/W2001863331","https://openalex.org/W2009126191","https://openalex.org/W2009603559","https://openalex.org/W2013721111","https://openalex.org/W2013887826","https://openalex.org/W2021805877","https://openalex.org/W2024954594","https://openalex.org/W2027105756","https://openalex.org/W2030439291","https://openalex.org/W2032278339","https://openalex.org/W2033561913","https://openalex.org/W2033829008","https://openalex.org/W2034219960","https://openalex.org/W2038228297","https://openalex.org/W2042878897","https://openalex.org/W2046604527","https://openalex.org/W2047366876","https://openalex.org/W2049739335","https://openalex.org/W2051496041","https://openalex.org/W2052745039","https://openalex.org/W2053330025","https://openalex.org/W2058967416","https://openalex.org/W2069215062","https://openalex.org/W2071758752","https://openalex.org/W2075494813","https://openalex.org/W2078565488","https://openalex.org/W2078731100","https://openalex.org/W2082522242","https://openalex.org/W2086569256","https://openalex.org/W2087961202","https://openalex.org/W2087983219","https://openalex.org/W2095560925","https://openalex.org/W2098351459","https://openalex.org/W2098733945","https://openalex.org/W2101078682","https://openalex.org/W2101224698","https://openalex.org/W2103486222","https://openalex.org/W2106248075","https://openalex.org/W2110223801","https://openalex.org/W2110443462","https://openalex.org/W2112612529","https://openalex.org/W2115542848","https://openalex.org/W2117212538","https://openalex.org/W2117840175","https://openalex.org/W2117855155","https://openalex.org/W2118314915","https://openalex.org/W2121966467","https://openalex.org/W2127991819","https://openalex.org/W2131225849","https://openalex.org/W2135823791","https://openalex.org/W2144669142","https://openalex.org/W2153643495","https://openalex.org/W2156580403","https://openalex.org/W2165647061","https://openalex.org/W2166737662","https://openalex.org/W2168619087","https://openalex.org/W2169716006","https://openalex.org/W2170682601","https://openalex.org/W2220948423","https://openalex.org/W2237194513","https://openalex.org/W2279126344","https://openalex.org/W2283341929","https://openalex.org/W2296598106","https://openalex.org/W2298951702","https://openalex.org/W2325283475","https://openalex.org/W2327361555","https://openalex.org/W2342023283","https://openalex.org/W2357386475","https://openalex.org/W2422420883","https://openalex.org/W2461517514","https://openalex.org/W2465261539","https://openalex.org/W2491976234","https://openalex.org/W2515479598","https://openalex.org/W2528888441","https://openalex.org/W2529006404","https://openalex.org/W2531779974","https://openalex.org/W2551520606","https://openalex.org/W2563367428","https://openalex.org/W2568627235","https://openalex.org/W2573032076","https://openalex.org/W2576924838","https://openalex.org/W2589094119","https://openalex.org/W2599276599","https://openalex.org/W2600481111","https://openalex.org/W2651023790","https://openalex.org/W2734776573","https://openalex.org/W2734898349","https://openalex.org/W2736204930","https://openalex.org/W2737953224","https://openalex.org/W2741651954","https://openalex.org/W2751702425","https://openalex.org/W2752941114","https://openalex.org/W2753393763","https://openalex.org/W2763661741","https://openalex.org/W2782417674","https://openalex.org/W2789910838","https://openalex.org/W2791013502","https://openalex.org/W2792932737","https://openalex.org/W2794127862","https://openalex.org/W2794260489","https://openalex.org/W2798213660","https://openalex.org/W2799999936","https://openalex.org/W2800348675","https://openalex.org/W2804681350","https://openalex.org/W2809323014","https://openalex.org/W2884882234","https://openalex.org/W2889898130","https://openalex.org/W2890735529","https://openalex.org/W2891486793","https://openalex.org/W2891536860","https://openalex.org/W2895629918","https://openalex.org/W2897907923","https://openalex.org/W2898251390","https://openalex.org/W2898719642","https://openalex.org/W2900611152","https://openalex.org/W2901944254","https://openalex.org/W2902260387","https://openalex.org/W2907300759","https://openalex.org/W2908564203","https://openalex.org/W2922774803","https://openalex.org/W2939145554","https://openalex.org/W2946239926","https://openalex.org/W2949683532","https://openalex.org/W2953433310","https://openalex.org/W2963487518","https://openalex.org/W2965086491","https://openalex.org/W2977024194","https://openalex.org/W2977771242","https://openalex.org/W2978612843","https://openalex.org/W2981063863","https://openalex.org/W2981632193","https://openalex.org/W2981840150","https://openalex.org/W2998139942","https://openalex.org/W3004625128","https://openalex.org/W3006330185","https://openalex.org/W3011417219","https://openalex.org/W3011494554","https://openalex.org/W3011663072","https://openalex.org/W3012375663","https://openalex.org/W3016510901","https://openalex.org/W3027138240","https://openalex.org/W3042833857","https://openalex.org/W3043722389","https://openalex.org/W3046463683","https://openalex.org/W3048364577","https://openalex.org/W3048594103","https://openalex.org/W3083750089","https://openalex.org/W3111255098","https://openalex.org/W3113734454","https://openalex.org/W3210545055","https://openalex.org/W4205483821","https://openalex.org/W4236618054","https://openalex.org/W4317676540","https://openalex.org/W6688476369","https://openalex.org/W6768703343"],"related_works":["https://openalex.org/W4309117417","https://openalex.org/W4382787047","https://openalex.org/W1986136296","https://openalex.org/W3027019949","https://openalex.org/W4385225033","https://openalex.org/W2064963672","https://openalex.org/W2982574566","https://openalex.org/W2001863331","https://openalex.org/W2981632193","https://openalex.org/W2150820813"],"abstract_inverted_index":{"The":[0,50],"development":[1],"of":[2,6,20,42,58,73,126],"vaccines":[3],"is":[4,69,89],"one":[5],"the":[7,56,70,103,107,128],"most":[8],"significant":[9],"medical":[10],"accomplishments":[11],"which":[12],"has":[13,23],"helped":[14],"to":[15,33,79,92,118],"eradicate":[16],"a":[17,81,115,120],"large":[18],"number":[19],"diseases.":[21],"It":[22],"undergone":[24],"an":[25,66,76],"evolutionary":[26],"process":[27],"from":[28,106],"live":[29],"attenuated":[30],"pathogen":[31],"vaccine":[32,95],"killed":[34],"whole":[35],"organisms":[36],"or":[37],"inactivated":[38],"toxins":[39],"(toxoids),":[40],"each":[41],"them":[43],"having":[44],"its":[45],"own":[46],"advantages":[47],"and":[48,61,97,111,135,144,153,163,171],"disadvantages.":[49],"crucial":[51],"parameters":[52],"in":[53,75,114],"vaccination":[54],"are":[55],"generation":[57],"memory":[59],"response":[60],"protection":[62],"against":[63],"infection,":[64],"while":[65],"important":[67],"aspect":[68],"effective":[71],"delivery":[72,98,136],"antigen":[74,105],"intelligent":[77],"manner":[78,117],"evoke":[80],"robust":[82],"immune":[83],"response.":[84],"In":[85,124],"this":[86],"regard,":[87],"nanotechnology":[88],"greatly":[90],"contributing":[91],"developing":[93],"efficient":[94],"adjuvants":[96,134],"systems.":[99],"These":[100],"can":[101],"protect":[102],"encapsulated":[104],"host's":[108],"in-vivo":[109],"environment":[110],"releasing":[112],"it":[113],"sustained":[116],"induce":[119],"long-lasting":[121],"immunostimulatory":[122],"effect.":[123],"view":[125],"this,":[127],"present":[129],"review":[130],"article":[131],"summarizes":[132],"nanoscale-based":[133],"vehicles":[137],"such":[138],"as":[139],"viral":[140],"vectors,":[141],"virus-like":[142],"particles":[143],"virosomes;":[145],"non-viral":[146],"vectors":[147],"namely":[148],"nanoemulsions,":[149],"lipid":[150],"nanocarriers,":[151],"biodegradable":[152],"non-degradable":[154],"nanoparticles,":[155,158,161],"calcium":[156],"phosphate":[157],"colloidally":[159],"stable":[160],"proteosomes;":[162],"pattern":[164],"recognition":[165],"receptors":[166,170],"covering":[167],"c-type":[168],"lectin":[169],"toll-like":[172],"receptors.":[173]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":24},{"year":2022,"cited_by_count":27},{"year":2021,"cited_by_count":7}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-04-13T00:00:00"}