{"id":"https://openalex.org/W3145501695","doi":"https://doi.org/10.1186/s12875-021-01415-x","title":"Reducing prescribing of benzodiazepines in older adults: a comparison of four physician-focused interventions by a medical regulatory authority","display_name":"Reducing prescribing of benzodiazepines in older adults: a comparison of four physician-focused interventions by a medical regulatory authority","publication_year":2021,"publication_date":"2021-04-08","ids":{"openalex":"https://openalex.org/W3145501695","doi":"https://doi.org/10.1186/s12875-021-01415-x","mag":"3145501695","pmid":"https://pubmed.ncbi.nlm.nih.gov/33832432","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8034172"},"language":"en","primary_location":{"id":"doi:10.1186/s12875-021-01415-x","doi":"https://doi.org/10.1186/s12875-021-01415-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12875-021-01415-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12875-021-01415-x.pdf","source":{"id":"https://openalex.org/S153257185","display_name":"BMC Family Practice","issn_l":"1471-2296","issn":["1471-2296","2731-4553"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Family Practice","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s12875-021-01415-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087832339","display_name":"Nigel L. Ashworth","orcid":"https://orcid.org/0000-0001-8221-9812","observed_orcids":["https://orcid.org/0000-0001-8221-9812"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]},{"id":"https://openalex.org/I4405273061","display_name":"College of Physicians and Surgeons of Alberta","ror":"https://ror.org/057erac45","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405273061"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Nigel Ashworth","raw_affiliation_strings":["Department of Medicine, University of Alberta, Edmonton, Canada. ashworth@ualberta.ca","Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada. ashworth@ualberta.ca","Department of Medicine, University of Alberta, Edmonton, Canada"],"raw_orcid":"https://orcid.org/0000-0001-8221-9812","affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Alberta, Edmonton, Canada. ashworth@ualberta.ca","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada. ashworth@ualberta.ca","institution_ids":["https://openalex.org/I154425047","https://openalex.org/I4405273061"]},{"raw_affiliation_string":"Department of Medicine, University of Alberta, Edmonton, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053812989","display_name":"Nicole Allison Kain","orcid":"https://orcid.org/0000-0002-9159-5841","observed_orcids":["https://orcid.org/0000-0002-9159-5841","https://orcid.org/0000-0003-4701-7873"]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]},{"id":"https://openalex.org/I4405273061","display_name":"College of Physicians and Surgeons of Alberta","ror":"https://ror.org/057erac45","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405273061"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nicole Kain","raw_affiliation_strings":["Department of Medicine, University of Alberta, Edmonton, Canada","Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Alberta, Edmonton, Canada","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada","institution_ids":["https://openalex.org/I4405273061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045587412","display_name":"Delaney Wiebe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405273061","display_name":"College of Physicians and Surgeons of Alberta","ror":"https://ror.org/057erac45","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405273061"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Delaney Wiebe","raw_affiliation_strings":["Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada","institution_ids":["https://openalex.org/I4405273061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025541723","display_name":"Nancy Hern\u00e1ndez-Cer\u00f3n","orcid":"https://orcid.org/0009-0002-1238-9941","observed_orcids":["https://orcid.org/0009-0002-1238-9941"]},"institutions":[{"id":"https://openalex.org/I4405273061","display_name":"College of Physicians and Surgeons of Alberta","ror":"https://ror.org/057erac45","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405273061"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nancy Hernandez-Ceron","raw_affiliation_strings":["Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada","institution_ids":["https://openalex.org/I4405273061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044189646","display_name":"Ed Jess","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405273061","display_name":"College of Physicians and Surgeons of Alberta","ror":"https://ror.org/057erac45","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405273061"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Ed Jess","raw_affiliation_strings":["Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada","institution_ids":["https://openalex.org/I4405273061"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015616109","display_name":"Karen Mazurek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405273061","display_name":"College of Physicians and Surgeons of Alberta","ror":"https://ror.org/057erac45","country_code":"CA","type":"education","lineage":["https://openalex.org/I4405273061"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Karen Mazurek","raw_affiliation_strings":["Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada","institution_ids":["https://openalex.org/I4405273061"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5087832339"],"corresponding_institution_ids":["https://openalex.org/I154425047","https://openalex.org/I4405273061"],"apc_list":{"value":2390,"currency":"USD","value_usd":2390},"apc_paid":{"value":2390,"currency":"USD","value_usd":2390},"fwci":1.3977,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.77939558,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"22","issue":"1","first_page":"68","last_page":"68"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10576","display_name":"Opioid Use Disorder Treatment","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11649","display_name":"Pharmaceutical industry and healthcare","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2910","display_name":"Issues, ethics and legal aspects"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzodiazepines","display_name":"benzodiazepines","score":0.9620000123977661},{"id":"https://openalex.org/keywords/z-drugs","display_name":"Z-drugs","score":0.8610000014305115},{"id":"https://openalex.org/keywords/inappropriate-prescribing","display_name":"inappropriate prescribing","score":0.8880000114440918},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9380000233650208},{"id":"https://openalex.org/keywords/physician-prescribing-behavior","display_name":"physician prescribing behavior","score":0.7580000162124634},{"id":"https://openalex.org/keywords/warning-letters","display_name":"warning letters","score":0.7329999804496765},{"id":"https://openalex.org/keywords/pharmacist-intervention","display_name":"pharmacist intervention","score":0.7429999709129333},{"id":"https://openalex.org/keywords/physician-intervention","display_name":"physician intervention","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8953065872192383},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.6515361070632935},{"id":"https://openalex.org/C2779457091","wikidata":"https://www.wikidata.org/wiki/Q105186","display_name":"Pharmacist","level":3,"score":0.6058939695358276},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6007733345031738},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.5229147672653198},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.44059547781944275},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.4234864413738251},{"id":"https://openalex.org/C104863432","wikidata":"https://www.wikidata.org/wiki/Q614304","display_name":"Pharmacy","level":2,"score":0.42084017395973206},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.19873926043510437},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16574373841285706},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.1642051339149475}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000416","descriptor_name":"Alberta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001569","descriptor_name":"Benzodiazepines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010595","descriptor_name":"Pharmacists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010820","descriptor_name":"Physicians","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057970","descriptor_name":"Inappropriate Prescribing","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/s12875-021-01415-x","doi":"https://doi.org/10.1186/s12875-021-01415-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12875-021-01415-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12875-021-01415-x.pdf","source":{"id":"https://openalex.org/S153257185","display_name":"BMC Family Practice","issn_l":"1471-2296","issn":["1471-2296","2731-4553"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Family Practice","raw_type":"journal-article"},{"id":"pmid:33832432","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33832432","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC family practice","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8034172","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8034172/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Fam Pract","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:ce28f998850f4a08ac255315574f48e6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ce28f998850f4a08ac255315574f48e6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Family Practice, Vol 22, Iss 1, Pp 1-9 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s12875-021-01415-x","doi":"https://doi.org/10.1186/s12875-021-01415-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12875-021-01415-x","pdf_url":"https://link.springer.com/content/pdf/10.1186/s12875-021-01415-x.pdf","source":{"id":"https://openalex.org/S153257185","display_name":"BMC Family Practice","issn_l":"1471-2296","issn":["1471-2296","2731-4553"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Family Practice","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3145501695.pdf","grobid_xml":"https://content.openalex.org/works/W3145501695.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W72861659","https://openalex.org/W1499108441","https://openalex.org/W1592645113","https://openalex.org/W1599942278","https://openalex.org/W1975817655","https://openalex.org/W2009679046","https://openalex.org/W2018685660","https://openalex.org/W2049132254","https://openalex.org/W2058009901","https://openalex.org/W2072620071","https://openalex.org/W2105204058","https://openalex.org/W2105501846","https://openalex.org/W2121494028","https://openalex.org/W2148791978","https://openalex.org/W2170043108","https://openalex.org/W2196823582","https://openalex.org/W2281412879","https://openalex.org/W2326647595","https://openalex.org/W2343853645","https://openalex.org/W2405525908","https://openalex.org/W2410547166","https://openalex.org/W2562081178","https://openalex.org/W2597966538","https://openalex.org/W2610505214","https://openalex.org/W2739913519","https://openalex.org/W2750525908","https://openalex.org/W2751648725","https://openalex.org/W2760380789","https://openalex.org/W2784098776","https://openalex.org/W2800072530","https://openalex.org/W2801221737","https://openalex.org/W2803370373","https://openalex.org/W2808092861","https://openalex.org/W2809119374","https://openalex.org/W2810179111","https://openalex.org/W2868794329","https://openalex.org/W2883791085","https://openalex.org/W2886185197","https://openalex.org/W2886446085","https://openalex.org/W2913117320","https://openalex.org/W4232350687","https://openalex.org/W4292909295"],"related_works":["https://openalex.org/W6920853606","https://openalex.org/W2147467149","https://openalex.org/W2067224084","https://openalex.org/W2432352834","https://openalex.org/W2073094486","https://openalex.org/W2417717473","https://openalex.org/W2800093210","https://openalex.org/W2524987563","https://openalex.org/W1852914478","https://openalex.org/W4283072709"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,18,119,276],"inappropriate":[2],"and/or":[3],"high":[4,254],"prescribing":[5,39,56,77,123,238,259,290],"of":[6,20,63,69,126,138,190,197,217,221,256,288,294],"benzodiazepine":[7],"and":[8,147,210,297,303],"'Z'":[9],"drugs":[10],"(BDZ":[11],"+)":[12],"is":[13],"a":[14,33,37,42,75,102,111,183,211,266,284],"major":[15],"health":[16],"concern.":[17],"purpose":[19],"this":[21],"study":[22],"was":[23,47,228],"to":[24,59,164,246,279],"determine":[25],"whether":[26],"physician":[27,206,269],"or":[28,32,36,65,110,268],"pharmacist":[29,109,267],"led":[30],"interventions":[31,264],"simple":[34],"letter":[35,98],"personalized":[38,76,237],"report":[40,239],"from":[41,99,106,115,242],"medical":[43],"regulatory":[44],"authority":[45],"(MRA)":[46],"the":[48,80,100,187,214,243],"most":[49],"effective":[50,249],"intervention":[51,250,277],"for":[52,157,175,251],"reducing":[53,252],"BDZ":[54,145,150,198,218,257,295],"+":[55,143,146,151,195,199,219,258,296],"by":[57,79,171,200,265],"physicians":[58,127],"patients":[60,140,192],"65":[61],"years":[62],"age":[64],"older.":[66],"METHODS:":[67],"quarter":[68],"2016.":[70],"All":[71,180],"physician-participants":[72],"were":[73,83,122],"sent":[74,241],"profile":[78],"MRA.":[81],"They":[82],"then":[84],"randomized":[85],"into":[86],"four":[87],"groups":[88,181],"that":[89,298],"received":[90],"either":[91],"nothing":[92],"more,":[93],"an":[94,107,116,248],"additional":[95,274],"personal":[96,103,112],"warning":[97],"MRA,":[101],"phone":[104,113],"call":[105,114],"MRA":[108,117,244],"physician.":[118,154],"main":[120,167],"outcomes":[121],"behavior":[124],"change":[125,134],"at":[128,207,300],"one":[129,208],"year":[130],"in":[131,135,186,213,260,273],"terms":[132],"of:":[133],"mean":[136,148,215],"number":[137,189],"older":[139,191,261],"receiving":[141,193],"4":[142,194],"DDD":[144,196],"dose":[149,216],"prescribed":[152,220],"per":[153,205],"To":[155],"adjust":[156],"multiple":[158],"statistical":[159],"testing,":[160],"we":[161],"used":[162],"MANCOVA":[163],"test":[165],"both":[166],"outcome":[168],"measures":[169],"simultaneously":[170],"group":[172],"whilst":[173],"controlling":[174],"any":[176],"baseline":[177],"differences.":[178],"RESULTS:":[179],"experienced":[182],"significant":[184,230],"fall":[185,212],"total":[188],"about":[201,222],"50%":[202],"(range":[203,224],"43-54%)":[204],"year,":[209],"13%":[223],"10-16%).":[225],"However,":[226],"there":[227],"no":[229],"difference":[231],"between":[232],"each":[233],"group.":[234],"CONCLUSIONS:":[235],"A":[236],"alone":[240],"appears":[245],"be":[247,280],"very":[253],"levels":[255],"patients.":[262],"Additional":[263],"did":[270],"not":[271],"result":[272],"benefit.":[275],"needs":[278],"tested":[281],"further":[282],"on":[283],"more":[285,301],"general":[286],"population":[287],"physicians,":[289],"less":[291],"extreme":[292],"doses":[293],"looks":[299],"clinical":[302],"healthcare":[304],"utilization":[305],"outcomes.":[306]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":8}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-04-13T00:00:00"}
