{"id":"https://openalex.org/W3144895151","doi":null,"title":"Infliximab reference product versus biosimilar for the treatment of rheumatoid arthritis : scoping report","display_name":"Infliximab reference product versus biosimilar for the treatment of rheumatoid arthritis : scoping report","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3144895151","mag":"3144895151"},"language":"en","primary_location":{"id":"pmh:oai:digitalcollection.zhaw.ch:11475/21951","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11475/21951","pdf_url":"https://www.bag.admin.ch/dam/de/sd-web/3RooeUZY0X7B/h0047infx-scoping-report.pdf","source":{"id":"https://openalex.org/S4306401811","display_name":"Z\u00fcrcher Hochschule f\u00fcr Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I858936495","host_organization_name":"ZHAW Zurich University of Applied Sciences","host_organization_lineage":["https://openalex.org/I858936495"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.bag.admin.ch/dam/de/sd-web/3RooeUZY0X7B/h0047infx-scoping-report.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053807623","display_name":"Johannes P\u00f6hlmann","orcid":"https://orcid.org/0000-0002-8065-755X","observed_orcids":["https://orcid.org/0000-0002-8065-755X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Johannes P\u00f6hlmann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038620713","display_name":"Renato Mattli","orcid":"https://orcid.org/0000-0002-8118-1776","observed_orcids":["https://orcid.org/0000-0002-8118-1776"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Renato Mattli","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8118-1776","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078500789","display_name":"Maria\u2010Eleni Syleouni","orcid":"https://orcid.org/0000-0003-2883-9679","observed_orcids":["https://orcid.org/0000-0003-2883-9679"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria\u2010Eleni Syleouni","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2883-9679","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058379913","display_name":"Maria Carlander","orcid":"https://orcid.org/0000-0001-8827-0133","observed_orcids":["https://orcid.org/0000-0001-8827-0133"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Carlander","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8827-0133","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103962909","display_name":"Flurina Meier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Flurina Meier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002171517","display_name":"Philipp Egli","orcid":"https://orcid.org/0000-0002-8390-6371","observed_orcids":["https://orcid.org/0000-0002-8390-6371"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Philipp Egli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032873017","display_name":"Andreas Gerber\u2010Grote","orcid":"https://orcid.org/0000-0003-2157-4065","observed_orcids":["https://orcid.org/0000-0003-2157-4065"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andreas Gerber\u2010Grote","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2157-4065","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5026185185","display_name":"Simon Wieser","orcid":"https://orcid.org/0000-0003-1821-2944","observed_orcids":["https://orcid.org/0000-0003-1821-2944"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Simon Wieser","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1821-2944","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/infliximab","display_name":"infliximab","score":0.9909999966621399},{"id":"https://openalex.org/keywords/biosimilars","display_name":"biosimilars","score":0.9670000076293945},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9589999914169312},{"id":"https://openalex.org/keywords/health-technology-assessment","display_name":"health technology assessment","score":0.7710000276565552},{"id":"https://openalex.org/keywords/biosimilar-regulation","display_name":"biosimilar regulation","score":0.5960000157356262},{"id":"https://openalex.org/keywords/budget-impact-analysis","display_name":"budget impact analysis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/immunogenicity","display_name":"immunogenicity","score":0.7080000042915344},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.7429999709129333},{"id":"https://openalex.org/keywords/real-world-evidence","display_name":"real-world evidence","score":0.7400000095367432},{"id":"https://openalex.org/keywords/health-economic-outcomes","display_name":"health economic outcomes","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C59491497","wikidata":"https://www.wikidata.org/wiki/Q864715","display_name":"Biosimilar","level":2,"score":0.9426289796829224},{"id":"https://openalex.org/C2777138892","wikidata":"https://www.wikidata.org/wiki/Q415264","display_name":"Infliximab","level":3,"score":0.8722692131996155},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.838820219039917},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7592043280601501},{"id":"https://openalex.org/C90673727","wikidata":"https://www.wikidata.org/wiki/Q901718","display_name":"Product (mathematics)","level":2,"score":0.4494284987449646},{"id":"https://openalex.org/C2909063479","wikidata":"https://www.wikidata.org/wiki/Q810254","display_name":"Antirheumatic Agents","level":3,"score":0.4363762140274048},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.41542935371398926},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.372862845659256},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28660720586776733},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.10467594861984253},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:digitalcollection.zhaw.ch:11475/21951","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11475/21951","pdf_url":"https://www.bag.admin.ch/dam/de/sd-web/3RooeUZY0X7B/h0047infx-scoping-report.pdf","source":{"id":"https://openalex.org/S4306401811","display_name":"Z\u00fcrcher Hochschule f\u00fcr Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I858936495","host_organization_name":"ZHAW Zurich University of Applied Sciences","host_organization_lineage":["https://openalex.org/I858936495"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"mag:3144895151","doi":null,"is_oa":false,"landing_page_url":"https://digitalcollection.zhaw.ch/handle/11475/21951","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:digitalcollection.zhaw.ch:11475/21951","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11475/21951","pdf_url":"https://www.bag.admin.ch/dam/de/sd-web/3RooeUZY0X7B/h0047infx-scoping-report.pdf","source":{"id":"https://openalex.org/S4306401811","display_name":"Z\u00fcrcher Hochschule f\u00fcr Angewandte Wissenschaften digital collection (Zurich University of Applied Sciences)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I858936495","host_organization_name":"ZHAW Zurich University of Applied Sciences","host_organization_lineage":["https://openalex.org/I858936495"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9074000120162964}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3144895151.pdf","grobid_xml":"https://content.openalex.org/works/W3144895151.grobid-xml"},"referenced_works_count":251,"referenced_works":["https://openalex.org/W108172154","https://openalex.org/W1251997985","https://openalex.org/W1484962366","https://openalex.org/W1553809360","https://openalex.org/W1561497241","https://openalex.org/W1608831349","https://openalex.org/W1824049500","https://openalex.org/W1845594800","https://openalex.org/W1909853035","https://openalex.org/W1966790580","https://openalex.org/W1971917624","https://openalex.org/W1978138475","https://openalex.org/W1981511266","https://openalex.org/W1986215651","https://openalex.org/W1989217623","https://openalex.org/W1995443607","https://openalex.org/W1996876159","https://openalex.org/W1997063318","https://openalex.org/W2003203361","https://openalex.org/W2006436962","https://openalex.org/W2012942455","https://openalex.org/W2015480191","https://openalex.org/W2015499663","https://openalex.org/W2023193839","https://openalex.org/W2023749561","https://openalex.org/W2025001196","https://openalex.org/W2028465542","https://openalex.org/W2031838098","https://openalex.org/W2033299724","https://openalex.org/W2034271610","https://openalex.org/W2040963445","https://openalex.org/W2048618042","https://openalex.org/W2052230616","https://openalex.org/W2059539909","https://openalex.org/W2060227370","https://openalex.org/W2068315097","https://openalex.org/W2081641593","https://openalex.org/W2085537320","https://openalex.org/W2087275189","https://openalex.org/W2089468569","https://openalex.org/W2091055562","https://openalex.org/W2091912215","https://openalex.org/W2093756446","https://openalex.org/W2093884168","https://openalex.org/W2094323797","https://openalex.org/W2098919737","https://openalex.org/W2099334955","https://openalex.org/W2099559598","https://openalex.org/W2104675861","https://openalex.org/W2106152050","https://openalex.org/W2109226190","https://openalex.org/W2109971928","https://openalex.org/W2117847674","https://openalex.org/W2121050884","https://openalex.org/W2122316162","https://openalex.org/W2128952811","https://openalex.org/W2130291034","https://openalex.org/W2131517206","https://openalex.org/W2137577059","https://openalex.org/W2138942616","https://openalex.org/W2141719028","https://openalex.org/W2146672820","https://openalex.org/W2152348310","https://openalex.org/W2152602115","https://openalex.org/W2153919578","https://openalex.org/W2155591144","https://openalex.org/W2159106700","https://openalex.org/W2160063906","https://openalex.org/W2161568142","https://openalex.org/W2162260707","https://openalex.org/W2162542566","https://openalex.org/W2168656049","https://openalex.org/W2169699670","https://openalex.org/W2178545546","https://openalex.org/W2189352316","https://openalex.org/W2198471696","https://openalex.org/W2203977709","https://openalex.org/W2210363578","https://openalex.org/W2267517345","https://openalex.org/W2274414307","https://openalex.org/W2275137129","https://openalex.org/W2281483877","https://openalex.org/W2282383992","https://openalex.org/W2293557195","https://openalex.org/W2295378770","https://openalex.org/W2310313429","https://openalex.org/W2314763045","https://openalex.org/W2317013895","https://openalex.org/W2326016332","https://openalex.org/W2331815567","https://openalex.org/W2334680921","https://openalex.org/W2335434080","https://openalex.org/W2342464058","https://openalex.org/W2347164991","https://openalex.org/W2395702777","https://openalex.org/W2397274083","https://openalex.org/W2410931357","https://openalex.org/W2412883467","https://openalex.org/W2465657364","https://openalex.org/W2508045778","https://openalex.org/W2516607409","https://openalex.org/W2520070907","https://openalex.org/W2521512376","https://openalex.org/W2530584466","https://openalex.org/W2531269403","https://openalex.org/W2540497002","https://openalex.org/W2543818161","https://openalex.org/W2545497673","https://openalex.org/W2546196047","https://openalex.org/W2547136071","https://openalex.org/W2559865294","https://openalex.org/W2565497969","https://openalex.org/W2567249615","https://openalex.org/W2568264987","https://openalex.org/W2568765207","https://openalex.org/W2588847707","https://openalex.org/W2589081615","https://openalex.org/W2601366102","https://openalex.org/W2606423638","https://openalex.org/W2608603956","https://openalex.org/W2610308940","https://openalex.org/W2613074462","https://openalex.org/W2613299853","https://openalex.org/W2616851837","https://openalex.org/W2617581275","https://openalex.org/W2618207514","https://openalex.org/W2619328451","https://openalex.org/W2623636343","https://openalex.org/W2732300460","https://openalex.org/W2733382837","https://openalex.org/W2734590607","https://openalex.org/W2736727076","https://openalex.org/W2739978627","https://openalex.org/W2743903835","https://openalex.org/W2748244654","https://openalex.org/W2754502404","https://openalex.org/W2755833300","https://openalex.org/W2764082441","https://openalex.org/W2766388803","https://openalex.org/W2767170461","https://openalex.org/W2767179430","https://openalex.org/W2767727558","https://openalex.org/W2768187732","https://openalex.org/W2769001638","https://openalex.org/W2769073434","https://openalex.org/W2769421422","https://openalex.org/W2769912785","https://openalex.org/W2770258755","https://openalex.org/W2778747082","https://openalex.org/W2782923730","https://openalex.org/W2783348148","https://openalex.org/W2784409714","https://openalex.org/W2786897800","https://openalex.org/W2793430933","https://openalex.org/W2793477763","https://openalex.org/W2793863949","https://openalex.org/W2793866077","https://openalex.org/W2794350945","https://openalex.org/W2797445804","https://openalex.org/W2801064477","https://openalex.org/W2801293105","https://openalex.org/W2804886519","https://openalex.org/W2805472045","https://openalex.org/W2806623595","https://openalex.org/W2806781107","https://openalex.org/W2806971308","https://openalex.org/W2807718844","https://openalex.org/W2811095538","https://openalex.org/W2842628275","https://openalex.org/W2883092434","https://openalex.org/W2883657995","https://openalex.org/W2885872617","https://openalex.org/W2887211036","https://openalex.org/W2889574927","https://openalex.org/W2890017737","https://openalex.org/W2890356222","https://openalex.org/W2890474965","https://openalex.org/W2890653293","https://openalex.org/W2891540343","https://openalex.org/W2894046119","https://openalex.org/W2894239243","https://openalex.org/W2894977001","https://openalex.org/W2895737827","https://openalex.org/W2897078225","https://openalex.org/W2899941886","https://openalex.org/W2901500377","https://openalex.org/W2904657106","https://openalex.org/W2905025921","https://openalex.org/W2906467871","https://openalex.org/W2907888286","https://openalex.org/W2909029941","https://openalex.org/W2910990828","https://openalex.org/W2913878532","https://openalex.org/W2913890755","https://openalex.org/W2916926950","https://openalex.org/W2926307819","https://openalex.org/W2930500067","https://openalex.org/W2931718880","https://openalex.org/W2933622020","https://openalex.org/W2938700508","https://openalex.org/W2939269238","https://openalex.org/W2943004339","https://openalex.org/W2944183815","https://openalex.org/W2946295704","https://openalex.org/W2946371282","https://openalex.org/W2947139337","https://openalex.org/W2947268672","https://openalex.org/W2949912383","https://openalex.org/W2951215699","https://openalex.org/W2951648271","https://openalex.org/W2952187361","https://openalex.org/W2954860113","https://openalex.org/W2955514849","https://openalex.org/W2956572553","https://openalex.org/W2956864182","https://openalex.org/W2965938015","https://openalex.org/W2965976428","https://openalex.org/W2969353747","https://openalex.org/W2970684805","https://openalex.org/W2971217817","https://openalex.org/W2971654130","https://openalex.org/W2973908960","https://openalex.org/W2979312036","https://openalex.org/W2984279764","https://openalex.org/W2985705185","https://openalex.org/W2986890803","https://openalex.org/W2988345887","https://openalex.org/W2990648940","https://openalex.org/W2991753424","https://openalex.org/W2996212167","https://openalex.org/W2996837618","https://openalex.org/W2997458303","https://openalex.org/W2999853201","https://openalex.org/W2999916750","https://openalex.org/W3000207999","https://openalex.org/W3000695215","https://openalex.org/W3002710369","https://openalex.org/W3003887243","https://openalex.org/W3011355568","https://openalex.org/W3011532946","https://openalex.org/W3014370677","https://openalex.org/W3122525660","https://openalex.org/W4210968471","https://openalex.org/W4211111012","https://openalex.org/W4231004324","https://openalex.org/W4231972505","https://openalex.org/W4237460531","https://openalex.org/W4246780304","https://openalex.org/W4253917565","https://openalex.org/W4293307140","https://openalex.org/W4294215472"],"related_works":["https://openalex.org/W7083352106","https://openalex.org/W3202784740","https://openalex.org/W3131434966","https://openalex.org/W3139590011","https://openalex.org/W6925318338","https://openalex.org/W4378348164","https://openalex.org/W7095481842","https://openalex.org/W2328043835","https://openalex.org/W3179809291","https://openalex.org/W2556301403"],"abstract_inverted_index":{"As":[0],"patents":[1],"for":[2,61,82,108,199,226],"first-to-market":[3],"biologics":[4],"expire,":[5],"subsequent-entry":[6],"products":[7,22,202],"\u2013":[8,10],"biosimilars":[9,60,99,225],"can":[11],"become":[12],"available.":[13],"Biosimilars":[14],"are":[15],"not":[16,264],"exact":[17],"copies":[18],"of":[19,53,72,92,143,175,193,228,251],"their":[20],"reference":[21,56,95,201,221],"but":[23],"highly":[24],"similar":[25],"with":[26,206,223],"regard":[27,207],"to":[28,59,98,208,242],"efficacy":[29],"and":[30,32,88,116,134,149,159,187,203,232,254],"safety":[31,255],"available":[33],"at":[34],"a":[35,48,78,105,141,244,249,259,266],"discount.":[36],"In":[37],"Switzerland,":[38],"relatively":[39],"low":[40],"biosimilar":[41,111,180],"prescription":[42],"rates":[43],"have":[44,241],"prompted":[45],"interest":[46],"in":[47,100,182,230],"health":[49,89,136],"technology":[50],"assessment":[51],"(HTA)":[52],"the":[54,70,93,219],"infliximab":[55,94,220],"product":[57,96,222],"relative":[58,97],"treating":[62],"rheumatoid":[63],"arthritis":[64],"(RA).":[65],"This":[66,238],"scoping":[67],"report":[68],"determines":[69],"feasibility":[71],"such":[73],"an":[74,216],"HTA.":[75],"We":[76,102,119],"conducted":[77,104],"systematic":[79,245],"literature":[80,176],"search":[81,107],"evidence":[83,109,131,212],"on":[84,110,124,156,179],"efficacy,":[85,145,252],"effectiveness,":[86,157,253],"safety,":[87,146,158],"economic":[90,137,163,268],"outcomes":[91],"RA.":[101],"also":[103],"targeted":[106],"related":[112],"ethical,":[113],"legal,":[114],"social,":[115],"organisational":[117],"aspects.":[118],"identified":[120,178],"15":[121],"studies":[122,153,164,167],"reporting":[123],"randomized":[125],"controlled":[126],"trials":[127],"(RCTs),":[128],"14":[129],"real-world":[130],"(RWE)":[132],"studies,":[133],"11":[135],"studies.":[138],"RCTs":[139],"reported":[140,155],"range":[142],"clinical":[144],"pharmacokinetic/pharmacodynamic,":[147],"immunogenicity,":[148],"patient-reported":[150],"outcomes.":[151],"RWE":[152],"primarily":[154],"treatment":[160,227],"discontinuation.":[161],"Health":[162],"were":[165],"costing":[166],"or":[168],"budget":[169,260],"impact":[170,261],"analyses.":[171],"A":[172],"substantial":[173],"body":[174],"was":[177],"regulation":[181],"different":[183],"settings.":[184],"For":[185],"legal":[186],"ethical":[188],"aspects,":[189],"we":[190,196],"developed":[191],"sets":[192],"questions":[194],"that":[195,215],"considered":[197],"important":[198],"discussing":[200],"biosimilars,":[204],"particularly":[205],"non-medical":[209],"switching.":[210],"The":[211],"base":[213],"suggested":[214],"HTA":[217,239],"comparing":[218],"its":[224],"RA":[229],"infliximab-na\u00efve":[231],"switched":[233],"patients":[234],"would":[235,240],"be":[236],"feasible.":[237],"include":[243],"review":[246],"(and":[247],"possibly":[248],"meta-analysis)":[250],"as":[256,258],"well":[257],"analysis":[262],"(but":[263],"necessarily":[265],"full":[267],"evaluation).":[269]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-04-13T00:00:00"}
