{"id":"https://openalex.org/W3143535652","doi":"https://doi.org/10.1016/j.amjms.2021.03.012","title":"Evaluation of Desmopressin in Critically Ill Patients with Hyponatremia Requiring 3% Hypertonic Saline","display_name":"Evaluation of Desmopressin in Critically Ill Patients with Hyponatremia Requiring 3% Hypertonic Saline","publication_year":2021,"publication_date":"2021-04-02","ids":{"openalex":"https://openalex.org/W3143535652","doi":"https://doi.org/10.1016/j.amjms.2021.03.012","mag":"3143535652","pmid":"https://pubmed.ncbi.nlm.nih.gov/33812910"},"language":"en","primary_location":{"id":"doi:10.1016/j.amjms.2021.03.012","doi":"https://doi.org/10.1016/j.amjms.2021.03.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.amjms.2021.03.012","pdf_url":null,"source":{"id":"https://openalex.org/S109361689","display_name":"The American Journal of the Medical Sciences","issn_l":"0002-9629","issn":["0002-9629","1538-2990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of the Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023585181","display_name":"Lena K. Tran","orcid":"https://orcid.org/0000-0002-7047-7512","observed_orcids":["https://orcid.org/0000-0002-7047-7512"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lena K. Tran","raw_affiliation_strings":["Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: lktran@bwh.harvard.edu","Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7047-7512","affiliations":[{"raw_affiliation_string":"Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA. Electronic address: lktran@bwh.harvard.edu","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049485963","display_name":"Kaylee K. Marino","orcid":"https://orcid.org/0000-0003-0003-0261","observed_orcids":["https://orcid.org/0000-0003-0003-0261"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kaylee K. Marino","raw_affiliation_strings":["Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064432475","display_name":"Jeremy R. DeGrado","orcid":"https://orcid.org/0000-0002-0141-7137","observed_orcids":["https://orcid.org/0000-0002-0141-7137"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy R. DeGrado","raw_affiliation_strings":["Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091794017","display_name":"Paul M. Szumita","orcid":"https://orcid.org/0000-0002-3679-7037","observed_orcids":["https://orcid.org/0000-0002-3679-7037"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul M. Szumita","raw_affiliation_strings":["Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081440930","display_name":"Kevin M. Dube","orcid":"https://orcid.org/0000-0002-5834-2981","observed_orcids":["https://orcid.org/0000-0002-5834-2981"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin M. Dube","raw_affiliation_strings":["Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5023585181"],"corresponding_institution_ids":["https://openalex.org/I1283280774"],"apc_list":{"value":2550,"currency":"USD","value_usd":2550},"apc_paid":null,"fwci":1.1733,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.76451645,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"361","issue":"6","first_page":"711","last_page":"717"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11623","display_name":"Hyperglycemia and glycemic control in critically ill and hospitalized patients","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/desmopressin","display_name":"desmopressin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/hyponatremia","display_name":"hyponatremia","score":0.9620000123977661},{"id":"https://openalex.org/keywords/hypertonic-saline","display_name":"hypertonic saline","score":0.9120000004768372},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.8809999823570251},{"id":"https://openalex.org/keywords/sodium-correction","display_name":"sodium correction","score":0.9610000252723694},{"id":"https://openalex.org/keywords/overcorrection","display_name":"overcorrection","score":0.9319999814033508},{"id":"https://openalex.org/keywords/icu-length-of-stay","display_name":"ICU length of stay","score":0.9089999794960022}],"concepts":[{"id":"https://openalex.org/C2776703092","wikidata":"https://www.wikidata.org/wiki/Q824292","display_name":"Hyponatremia","level":2,"score":0.9418094158172607},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8795322179794312},{"id":"https://openalex.org/C3017567848","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Hypertonic saline","level":2,"score":0.7795448303222656},{"id":"https://openalex.org/C2778702241","wikidata":"https://www.wikidata.org/wiki/Q241006","display_name":"Desmopressin","level":2,"score":0.6412025690078735},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.591291606426239},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.5675927996635437},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.4996039867401123},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4921678900718689},{"id":"https://openalex.org/C2778864100","wikidata":"https://www.wikidata.org/wiki/Q1132653","display_name":"Hypernatremia","level":3,"score":0.48065388202667236},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4541929364204407},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.43842872977256775},{"id":"https://openalex.org/C117277713","wikidata":"https://www.wikidata.org/wiki/Q925744","display_name":"Tonicity","level":2,"score":0.41690725088119507},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3344533443450928},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31358006596565247},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003894","descriptor_name":"Deamino Arginine Vasopressin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007010","descriptor_name":"Hyponatremia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007010","descriptor_name":"Hyponatremia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007010","descriptor_name":"Hyponatremia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012462","descriptor_name":"Saline Solution, Hypertonic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D050034","descriptor_name":"Antidiuretic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.amjms.2021.03.012","doi":"https://doi.org/10.1016/j.amjms.2021.03.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.amjms.2021.03.012","pdf_url":null,"source":{"id":"https://openalex.org/S109361689","display_name":"The American Journal of the Medical Sciences","issn_l":"0002-9629","issn":["0002-9629","1538-2990"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of the Medical Sciences","raw_type":"journal-article"},{"id":"pmid:33812910","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33812910","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of the medical sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W100590704","https://openalex.org/W398142341","https://openalex.org/W1967480820","https://openalex.org/W1976053112","https://openalex.org/W1976698511","https://openalex.org/W1979953150","https://openalex.org/W1986857885","https://openalex.org/W1988745016","https://openalex.org/W1997002555","https://openalex.org/W2007157220","https://openalex.org/W2009509231","https://openalex.org/W2025101749","https://openalex.org/W2032350593","https://openalex.org/W2073828698","https://openalex.org/W2110248150","https://openalex.org/W2114676903","https://openalex.org/W2126782124","https://openalex.org/W2130397559","https://openalex.org/W2141858669","https://openalex.org/W2143929271","https://openalex.org/W2157268264","https://openalex.org/W2315976593","https://openalex.org/W2418748046","https://openalex.org/W2732073298","https://openalex.org/W2766780274","https://openalex.org/W2782396995","https://openalex.org/W2794057023","https://openalex.org/W2843126921","https://openalex.org/W2921488859","https://openalex.org/W2985735828","https://openalex.org/W4247433669","https://openalex.org/W4294554863"],"related_works":["https://openalex.org/W4403833694","https://openalex.org/W4409764199","https://openalex.org/W2794057023","https://openalex.org/W398142341","https://openalex.org/W7140172876","https://openalex.org/W2766780274","https://openalex.org/W4389766216","https://openalex.org/W1979953150","https://openalex.org/W7165924072","https://openalex.org/W3136830160"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-04-13T00:00:00"}