{"id":"https://openalex.org/W3142425130","doi":"https://doi.org/10.3390/ijms22073680","title":"Molecular Mechanism of Cannabinoids in Cancer Progression","display_name":"Molecular Mechanism of Cannabinoids in Cancer Progression","publication_year":2021,"publication_date":"2021-04-01","ids":{"openalex":"https://openalex.org/W3142425130","doi":"https://doi.org/10.3390/ijms22073680","mag":"3142425130","pmid":"https://pubmed.ncbi.nlm.nih.gov/33916164"},"language":"en","primary_location":{"id":"doi:10.3390/ijms22073680","doi":"https://doi.org/10.3390/ijms22073680","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms22073680","pdf_url":"https://www.mdpi.com/1422-0067/22/7/3680/pdf?version=1617939353","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/22/7/3680/pdf?version=1617939353","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086634321","display_name":"Cristina Pagano","orcid":"https://orcid.org/0000-0002-9181-6595","observed_orcids":["https://orcid.org/0000-0002-9181-6595"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cristina Pagano","raw_affiliation_strings":["Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0002-9181-6595","affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017153674","display_name":"Giovanna Navarra","orcid":"https://orcid.org/0000-0001-6255-6731","observed_orcids":["https://orcid.org/0000-0001-6255-6731"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giovanna Navarra","raw_affiliation_strings":["Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009841397","display_name":"Laura Coppola","orcid":"https://orcid.org/0000-0002-5609-2464","observed_orcids":["https://orcid.org/0000-0002-5609-2464"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Coppola","raw_affiliation_strings":["Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023657474","display_name":"Maurizio Bifulco","orcid":"https://orcid.org/0000-0002-1771-4531","observed_orcids":["https://orcid.org/0000-0002-1771-4531"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Maurizio Bifulco","raw_affiliation_strings":["Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \u201cFederico II\u201d, Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Department of Molecular Medicine and Medical Biotechnology, University of Naples \"Federico II\", Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049005627","display_name":"Chiara Laezza","orcid":"https://orcid.org/0000-0003-0939-8767","observed_orcids":["https://orcid.org/0000-0003-0939-8767"]},"institutions":[{"id":"https://openalex.org/I4210139435","display_name":"Institute for Experimental Endocrinology and Oncology","ror":"https://ror.org/04sn06036","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210139435","https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Chiara Laezza","raw_affiliation_strings":["Institute of Endocrinology and Experimental Oncology, IEOS CNR, Via Pansini 5, 80131 Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Endocrinology and Experimental Oncology, IEOS CNR, Via Pansini 5, 80131 Naples, Italy","institution_ids":["https://openalex.org/I4210139435"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5023657474","https://openalex.org/A5049005627"],"corresponding_institution_ids":["https://openalex.org/I4210139435","https://openalex.org/I71267560"],"apc_list":{"value":2000,"currency":"CHF","value_usd":2160},"apc_paid":{"value":2000,"currency":"CHF","value_usd":2160},"fwci":7.5692,"has_fulltext":true,"cited_by_count":96,"citation_normalized_percentile":{"value":0.98545883,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"22","issue":"7","first_page":"3680","last_page":"3680"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12626","display_name":"Cancer, Stress, Anesthesia, and Immune Response","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cannabinoids","display_name":"cannabinoids","score":1.0},{"id":"https://openalex.org/keywords/endocannabinoid-system","display_name":"endocannabinoid system","score":0.9330000281333923},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.9850000143051147},{"id":"https://openalex.org/keywords/anticancer-mechanism","display_name":"anticancer mechanism","score":0.7239999771118164},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.9330000281333923},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.6909999847412109},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7590000033378601},{"id":"https://openalex.org/keywords/tumor-angiogenesis","display_name":"tumor angiogenesis","score":0.7639999985694885},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7009999752044678},{"id":"https://openalex.org/keywords/cell-migration-and-invasion","display_name":"cell migration and invasion","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C46721173","wikidata":"https://www.wikidata.org/wiki/Q368952","display_name":"Endocannabinoid system","level":3,"score":0.81353759765625},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.6489683389663696},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.6359387636184692},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.6348042488098145},{"id":"https://openalex.org/C2776120743","wikidata":"https://www.wikidata.org/wiki/Q3271540","display_name":"Mechanism of action","level":3,"score":0.5737500190734863},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5564000606536865},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5549368858337402},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5258595943450928},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5061497092247009},{"id":"https://openalex.org/C148001335","wikidata":"https://www.wikidata.org/wiki/Q421237","display_name":"Cannabinoid receptor","level":4,"score":0.5044187307357788},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5037450194358826},{"id":"https://openalex.org/C2779256057","wikidata":"https://www.wikidata.org/wiki/Q16909647","display_name":"Tumor progression","level":3,"score":0.4628680348396301},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.39735159277915955},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.38080325722694397},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34773826599121094},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.19482681155204773},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12052258849143982},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002186","descriptor_name":"Cannabinoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002186","descriptor_name":"Cannabinoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002186","descriptor_name":"Cannabinoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002186","descriptor_name":"Cannabinoids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002186","descriptor_name":"Cannabinoids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002186","descriptor_name":"Cannabinoids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063388","descriptor_name":"Endocannabinoids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063388","descriptor_name":"Endocannabinoids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D063388","descriptor_name":"Endocannabinoids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/ijms22073680","doi":"https://doi.org/10.3390/ijms22073680","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms22073680","pdf_url":"https://www.mdpi.com/1422-0067/22/7/3680/pdf?version=1617939353","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmid:33916164","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33916164","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8037087","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8037087","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Int J Mol Sci","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:e0ff8b8adafb4283ac63c35584ee3751","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e0ff8b8adafb4283ac63c35584ee3751","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Molecular Sciences, Vol 22, Iss 3680, p 3680 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ijms22073680","doi":"https://doi.org/10.3390/ijms22073680","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms22073680","pdf_url":"https://www.mdpi.com/1422-0067/22/7/3680/pdf?version=1617939353","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8500000238418579,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322218","display_name":"Regione Campania","ror":"https://ror.org/02kg21794"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3142425130.pdf","grobid_xml":"https://content.openalex.org/works/W3142425130.grobid-xml"},"referenced_works_count":126,"referenced_works":["https://openalex.org/W1096696135","https://openalex.org/W1490110546","https://openalex.org/W1527271824","https://openalex.org/W1576305824","https://openalex.org/W1636749516","https://openalex.org/W1840510814","https://openalex.org/W1844090762","https://openalex.org/W1896798605","https://openalex.org/W1898702228","https://openalex.org/W1968640233","https://openalex.org/W1975813687","https://openalex.org/W1978889496","https://openalex.org/W1979788933","https://openalex.org/W1984311964","https://openalex.org/W1986740576","https://openalex.org/W1991170299","https://openalex.org/W1994816149","https://openalex.org/W1996629211","https://openalex.org/W1997914837","https://openalex.org/W1998730664","https://openalex.org/W1998837142","https://openalex.org/W2005295755","https://openalex.org/W2020825180","https://openalex.org/W2023235628","https://openalex.org/W2027503449","https://openalex.org/W2029311374","https://openalex.org/W2033362135","https://openalex.org/W2035401358","https://openalex.org/W2035916997","https://openalex.org/W2036052195","https://openalex.org/W2045088285","https://openalex.org/W2053385355","https://openalex.org/W2054961000","https://openalex.org/W2056818713","https://openalex.org/W2057739367","https://openalex.org/W2058041563","https://openalex.org/W2063988920","https://openalex.org/W2071658340","https://openalex.org/W2081352174","https://openalex.org/W2085570576","https://openalex.org/W2086066816","https://openalex.org/W2087250130","https://openalex.org/W2087557532","https://openalex.org/W2089039955","https://openalex.org/W2089229091","https://openalex.org/W2098228155","https://openalex.org/W2098543425","https://openalex.org/W2100829842","https://openalex.org/W2102182608","https://openalex.org/W2103022109","https://openalex.org/W2108384479","https://openalex.org/W2109890960","https://openalex.org/W2113421289","https://openalex.org/W2122238010","https://openalex.org/W2127624416","https://openalex.org/W2128652347","https://openalex.org/W2131933487","https://openalex.org/W2132860096","https://openalex.org/W2143949606","https://openalex.org/W2144898517","https://openalex.org/W2148626765","https://openalex.org/W2150054500","https://openalex.org/W2150280637","https://openalex.org/W2158599133","https://openalex.org/W2190981294","https://openalex.org/W2218595127","https://openalex.org/W2227295428","https://openalex.org/W2228677581","https://openalex.org/W2261860681","https://openalex.org/W2262604014","https://openalex.org/W2291450370","https://openalex.org/W2324311973","https://openalex.org/W2335971122","https://openalex.org/W2401948043","https://openalex.org/W2404591934","https://openalex.org/W2486870205","https://openalex.org/W2532344261","https://openalex.org/W2532586679","https://openalex.org/W2533551977","https://openalex.org/W2538343965","https://openalex.org/W2547093525","https://openalex.org/W2552035785","https://openalex.org/W2555186487","https://openalex.org/W2560132780","https://openalex.org/W2586473686","https://openalex.org/W2587553356","https://openalex.org/W2591427933","https://openalex.org/W2750999729","https://openalex.org/W2751184419","https://openalex.org/W2761276964","https://openalex.org/W2770091578","https://openalex.org/W2790631595","https://openalex.org/W2800218694","https://openalex.org/W2804745469","https://openalex.org/W2891364782","https://openalex.org/W2892115080","https://openalex.org/W2933035888","https://openalex.org/W2947786629","https://openalex.org/W2947951130","https://openalex.org/W2963778961","https://openalex.org/W2981688260","https://openalex.org/W2983063248","https://openalex.org/W2990884500","https://openalex.org/W2992838111","https://openalex.org/W2997599459","https://openalex.org/W2999795626","https://openalex.org/W3001018370","https://openalex.org/W3002715242","https://openalex.org/W3005991537","https://openalex.org/W3022913886","https://openalex.org/W3029414653","https://openalex.org/W3035529059","https://openalex.org/W3043020437","https://openalex.org/W3044152183","https://openalex.org/W3045475100","https://openalex.org/W3045782809","https://openalex.org/W3092700553","https://openalex.org/W3093394106","https://openalex.org/W3097411329","https://openalex.org/W3100636377","https://openalex.org/W4233417116","https://openalex.org/W4233474160","https://openalex.org/W4236802598","https://openalex.org/W6638862950","https://openalex.org/W6815558759","https://openalex.org/W7073704150"],"related_works":["https://openalex.org/W4380301998","https://openalex.org/W2201563430","https://openalex.org/W2083859343","https://openalex.org/W2417206429","https://openalex.org/W1996653993","https://openalex.org/W2044311961","https://openalex.org/W3090354614","https://openalex.org/W2523035000","https://openalex.org/W19404521","https://openalex.org/W2069967676"],"abstract_inverted_index":{"Cannabinoids":[0],"are":[1],"a":[2],"family":[3],"of":[4,52,60,70,72],"heterogeneous":[5],"compounds":[6],"that":[7],"mostly":[8],"interact":[9],"with":[10],"receptors":[11],"eliciting":[12],"several":[13],"physiological":[14],"effects":[15,42],"both":[16,49],"in":[17,25,37,75,79],"the":[18,41,50,58,61,68,73],"central":[19],"and":[20,24,54,86],"peripheral":[21,26],"nervous":[22],"systems":[23],"organs.":[27],"They":[28],"exert":[29],"anticancer":[30],"action":[31,56,71],"by":[32,44],"modulating":[33],"signaling":[34,76],"pathways":[35,77],"involved":[36,78],"cancer":[38,80],"progression;":[39],"furthermore,":[40],"induced":[43],"their":[45,55],"use":[46],"depend":[47],"on":[48,57],"type":[51],"tumor":[53,87],"components":[59],"endocannabinoid":[62],"system.":[63],"This":[64],"review":[65],"will":[66],"explore":[67],"mechanism":[69],"cannabinoids":[74],"proliferation,":[81],"neovascularisation,":[82],"migration,":[83],"invasion,":[84],"metastasis,":[85],"angiogenesis.":[88]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":19},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":4}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}