{"id":"https://openalex.org/W3140986940","doi":"https://doi.org/10.1002/cncr.33543","title":"Prostate\u2010specific antigen nadir and testosterone level at prostate\u2010specific antigen failure following radiation and androgen suppression therapy for unfavorable\u2010risk prostate cancer and the risk of all\u2010cause and prostate cancer\u2013specific mortality","display_name":"Prostate\u2010specific antigen nadir and testosterone level at prostate\u2010specific antigen failure following radiation and androgen suppression therapy for unfavorable\u2010risk prostate cancer and the risk of all\u2010cause and prostate cancer\u2013specific mortality","publication_year":2021,"publication_date":"2021-04-06","ids":{"openalex":"https://openalex.org/W3140986940","doi":"https://doi.org/10.1002/cncr.33543","mag":"3140986940","pmid":"https://pubmed.ncbi.nlm.nih.gov/33823065","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/9436009"},"language":"en","primary_location":{"id":"doi:10.1002/cncr.33543","doi":"https://doi.org/10.1002/cncr.33543","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cncr.33543","pdf_url":null,"source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9436009","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039369605","display_name":"Danielle S. Bitterman","orcid":"https://orcid.org/0000-0003-0345-2232","observed_orcids":["https://orcid.org/0000-0003-0345-2232"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Danielle S. Bitterman","raw_affiliation_strings":["Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts","Harvard Radiation Oncology Program, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0003-0345-2232","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994"]},{"raw_affiliation_string":"Harvard Radiation Oncology Program, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210161994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100678189","display_name":"Ming\u2010Hui Chen","orcid":"https://orcid.org/0000-0003-1935-2447","observed_orcids":["https://orcid.org/0000-0003-1935-2447"]},"institutions":[{"id":"https://openalex.org/I140172145","display_name":"University of Connecticut","ror":"https://ror.org/02der9h97","country_code":"US","type":"education","lineage":["https://openalex.org/I140172145"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ming\u2010Hui Chen","raw_affiliation_strings":["Department of Statistics, University of Connecticut, Storrs, Connecticut"],"raw_orcid":"https://orcid.org/0000-0003-1935-2447","affiliations":[{"raw_affiliation_string":"Department of Statistics, University of Connecticut, Storrs, Connecticut","institution_ids":["https://openalex.org/I140172145"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048740236","display_name":"Jing Wu","orcid":"https://orcid.org/0000-0001-7808-6981","observed_orcids":["https://orcid.org/0000-0001-7808-6981","https://orcid.org/0000-0003-3615-4581"]},"institutions":[{"id":"https://openalex.org/I17626003","display_name":"University of Rhode Island","ror":"https://ror.org/013ckk937","country_code":"US","type":"education","lineage":["https://openalex.org/I17626003"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jing Wu","raw_affiliation_strings":["Department of Computer Science and Statistics, University of Rhode Island, Kingston, Rhode Island"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Statistics, University of Rhode Island, Kingston, Rhode Island","institution_ids":["https://openalex.org/I17626003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020110978","display_name":"Andrew A. Renshaw","orcid":"https://orcid.org/0000-0002-1318-4238","observed_orcids":["https://orcid.org/0000-0002-1318-4238"]},"institutions":[{"id":"https://openalex.org/I1292848113","display_name":"Baptist Hospital of Miami","ror":"https://ror.org/000pfrh90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1292848113","https://openalex.org/I4210097785"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew A. Renshaw","raw_affiliation_strings":["Department of Pathology, Baptist Hospital and Miami Cancer Institute, Miami, Florida"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Baptist Hospital and Miami Cancer Institute, Miami, Florida","institution_ids":["https://openalex.org/I1292848113"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070767858","display_name":"Marian J. Loffredo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marian Loffredo","raw_affiliation_strings":["Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056766924","display_name":"Philip W. Kantoff","orcid":"https://orcid.org/0000-0001-7275-0597","observed_orcids":["https://orcid.org/0000-0001-7275-0597"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip W. Kantoff","raw_affiliation_strings":["Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007578304","display_name":"Eric Jay Small","orcid":"https://orcid.org/0000-0003-3191-6268","observed_orcids":["https://orcid.org/0000-0003-3191-6268"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric J. Small","raw_affiliation_strings":["Department of Medicine, University of California San Francisco, San Francisco, California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of California San Francisco, San Francisco, California","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072365761","display_name":"Anthony Victor D'Amico","orcid":"https://orcid.org/0000-0002-4084-9944","observed_orcids":["https://orcid.org/0000-0002-4084-9944"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210161994","display_name":"Dana-Farber Brigham Cancer Center","ror":"https://ror.org/05rgrbr06","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony V. D'Amico","raw_affiliation_strings":["Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I4210117453","https://openalex.org/I4210161994"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5039369605"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210161994"],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":0.3194,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55013233,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"127","issue":"15","first_page":"2623","last_page":"2630"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9731000065803528,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.020800000056624413,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-specific-antigen-nadir","display_name":"prostate-specific antigen nadir","score":0.9399999976158142},{"id":"https://openalex.org/keywords/serum-testosterone","display_name":"serum testosterone","score":0.7770000100135803},{"id":"https://openalex.org/keywords/prostate-specific-antigen-failure","display_name":"prostate-specific antigen failure","score":0.843999981880188},{"id":"https://openalex.org/keywords/androgen-deprivation-therapy","display_name":"androgen deprivation therapy","score":0.8259999752044678},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.8360000252723694},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.8410000205039978},{"id":"https://openalex.org/keywords/prostate-cancer-specific-mortality","display_name":"prostate cancer-specific mortality","score":0.9940000176429749},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9169999957084656},{"id":"https://openalex.org/keywords/competing-risks","display_name":"competing risks","score":0.656000018119812},{"id":"https://openalex.org/keywords/non-metastatic-prostate-cancer","display_name":"non-metastatic prostate cancer","score":0.8759999871253967},{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.5590000152587891},{"id":"https://openalex.org/keywords/gleason-score","display_name":"Gleason score","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9188201427459717},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.9072165489196777},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.7669509053230286},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5751515626907349},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.573479413986206},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49336162209510803},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.48849761486053467},{"id":"https://openalex.org/C2778559712","wikidata":"https://www.wikidata.org/wiki/Q4759442","display_name":"Androgen suppression","level":4,"score":0.47428327798843384},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.4651886522769928},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.44192349910736084},{"id":"https://openalex.org/C87874733","wikidata":"https://www.wikidata.org/wiki/Q18039844","display_name":"PCA3","level":4,"score":0.42709147930145264},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4103521704673767},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.37755054235458374},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.36047786474227905},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.18753266334533691},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15234848856925964}],"mesh":[{"descriptor_ui":"D000726","descriptor_name":"Androgen Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000728","descriptor_name":"Androgens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D017430","descriptor_name":"Prostate-Specific Antigen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1002/cncr.33543","doi":"https://doi.org/10.1002/cncr.33543","is_oa":false,"landing_page_url":"https://doi.org/10.1002/cncr.33543","pdf_url":null,"source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},{"id":"pmid:33823065","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33823065","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9436009","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9436009","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.uri.edu:cs_facpubs-1115","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.uri.edu/cs_facpubs/115","pdf_url":null,"source":{"id":"https://openalex.org/S2764761010","display_name":"Journal of Media Literacy Education","issn_l":"2167-8715","issn":["2167-8715"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","jufo-1","norway-1","poland-20","russia-white-list-4","vabb-shw"],"host_organization":"https://openalex.org/P4310316378","host_organization_name":"National Association for Media Literacy Education","host_organization_lineage":["https://openalex.org/P4310316378"],"host_organization_lineage_names":["National Association for Media Literacy Education"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computer Science and Statistics Faculty Publications","raw_type":"text"},{"id":"pmh:oai:scholarlycommons.baptisthealth.net:se-all-publications-5101","doi":null,"is_oa":false,"landing_page_url":"https://scholarlycommons.baptisthealth.net/cgi/viewcontent.cgi?article=5101&context=se-all-publications","pdf_url":null,"source":{"id":"https://openalex.org/S4377196589","display_name":"Scholarly Commons - Baptist Health South Florida (Baptist Health South Florida)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210097785","host_organization_name":"Baptist Health South Florida","host_organization_lineage":["https://openalex.org/I4210097785"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"All Publications","raw_type":"text"},{"id":"pmh:oai:scholarlycommons.baptisthealth.net:se-all-publications-5261","doi":null,"is_oa":false,"landing_page_url":"https://scholarlycommons.baptisthealth.net/se-all-publications/4054","pdf_url":null,"source":{"id":"https://openalex.org/S4377196589","display_name":"Scholarly Commons - Baptist Health South Florida (Baptist Health South Florida)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210097785","host_organization_name":"Baptist Health South Florida","host_organization_lineage":["https://openalex.org/I4210097785"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"All Publications","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9436009","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9436009","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Cancer","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W571448349","https://openalex.org/W1580788756","https://openalex.org/W1972125775","https://openalex.org/W1976823981","https://openalex.org/W1979300931","https://openalex.org/W1979665150","https://openalex.org/W1979819510","https://openalex.org/W1986114421","https://openalex.org/W1994351520","https://openalex.org/W1996422254","https://openalex.org/W1999130958","https://openalex.org/W2017132929","https://openalex.org/W2026190552","https://openalex.org/W2032361474","https://openalex.org/W2038981426","https://openalex.org/W2044205039","https://openalex.org/W2053295005","https://openalex.org/W2055346449","https://openalex.org/W2062412101","https://openalex.org/W2073140442","https://openalex.org/W2093867637","https://openalex.org/W2098307421","https://openalex.org/W2103003357","https://openalex.org/W2106285196","https://openalex.org/W2110534364","https://openalex.org/W2117792530","https://openalex.org/W2120292596","https://openalex.org/W2126843316","https://openalex.org/W2135826149","https://openalex.org/W2142466432","https://openalex.org/W2148643283","https://openalex.org/W2150865892","https://openalex.org/W2152314979","https://openalex.org/W2152411252","https://openalex.org/W2155949904","https://openalex.org/W2166918329","https://openalex.org/W2168108459","https://openalex.org/W2178139012","https://openalex.org/W2214621962","https://openalex.org/W2290195878","https://openalex.org/W2499292135","https://openalex.org/W2502134830","https://openalex.org/W2574050600","https://openalex.org/W2756840809","https://openalex.org/W2769578203","https://openalex.org/W2777544969","https://openalex.org/W2792086148","https://openalex.org/W2810806599","https://openalex.org/W2911188335","https://openalex.org/W2913767564","https://openalex.org/W2945522282","https://openalex.org/W2975433160","https://openalex.org/W3147894994","https://openalex.org/W4246176192"],"related_works":["https://openalex.org/W2777544969","https://openalex.org/W2791928484","https://openalex.org/W4405084952","https://openalex.org/W2910463024","https://openalex.org/W2790102002","https://openalex.org/W2921033934","https://openalex.org/W2266799595","https://openalex.org/W1976823981","https://openalex.org/W2152411252","https://openalex.org/W2025309746"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"both":[2,316],"PSA":[3,10,94,145,214,221,249,282,322,339],"nadir":[4,272,323],"(PSAn)":[5],"and":[6,22,68,76,96,111,166,236,259,273,295],"testosterone":[7,89,143,212,218,243,277,336],"levels":[8,244,337],"at":[9,90,144,213,220,245,278,338],"failure":[11,95,146,222,283],"are":[12],"known":[13],"prognostic":[14,37,118,200,289,318,330],"factors":[15],"in":[16,61,207,223,332],"men":[17,45,208,240,333],"undergoing":[18],"radiation":[19,294],"therapy":[20,25,101,298],"(RT)":[21],"androgen":[23,296],"deprivation":[24,297],"(ADT)":[26],"for":[27,56,116,299],"unfavorable-risk":[28,57,300],"prostate":[29,303],"cancer":[30,304],"(PC),":[31],"it":[32],"is":[33,39,231],"unclear":[34],"whether":[35,84,267],"their":[36],"significance":[38,201,331],"independent":[40],"or":[41,50,287],"overlapping.":[42],"METHODS:":[43],"Seventy-five":[44],"treated":[46,228],"with":[47,49,105,150,209,226,229,233,241,256,293,302,334],"RT":[48,230],"without":[51],"6":[52],"months":[53],"of":[54,93,108,125,154,202,248,281,329],"ADT":[55],"nonmetastatic":[58],"PC":[59,117,227],"enrolled":[60],"2":[62,308],"prospective":[63,309],"clinical":[64,310],"trials":[65],"between":[66],"1986":[67],"2001":[69],"formed":[70],"the":[71,91,106,199,246,268,279],"study":[72,265],"cohort.":[73],"Competing":[74],"risks":[75],"Cox":[77],"multivariable":[78],"regression":[79],"were":[80,102,133,139],"used":[81],"to":[82,327],"assess":[83],"low":[85,276],"versus":[86,275],"normal":[87,211,242,274,335],"serum":[88],"time":[92,247,280],"higher":[97,178,321],"PSAn":[98,179,203,253],"after":[99],"initial":[100],"independently":[103],"associated":[104,149,232,255],"risk":[107,153],"PC-specific":[109],"(PCSM)":[110],"all-cause":[112],"mortality":[113],"(ACM)":[114],"adjusting":[115],"factors.":[119],"RESULTS:":[120],"After":[121],"a":[122,210],"median":[123],"follow-up":[124],"15.34":[126],"years":[127],"(interquartile":[128],"range,":[129],"6.66-16.88":[130],"years),":[131],"there":[132],"53":[134],"deaths":[135],"(73.3%):":[136],"30":[137],"(56.6%)":[138],"from":[140,307],"PC.":[141],"Low":[142,217],"was":[147,177,204,254,313,324],"significantly":[148],"an":[151,251],"increased":[152,234],"PCSM":[155,235,258],"(adjusted":[156],"HR":[157],"[AHR],":[158],"7.77;":[159],"95%":[160,170,183,192],"CI,":[161,171,184,193],"1.14-52.99;":[162],"P":[163,173,186,195],"=":[164,174],".04)":[165],"ACM":[167,189,237,260],"(AHR,":[168],"3.01;":[169],"1.01-8.96;":[172],".05),":[175],"as":[176],"(PCSM":[180],"AHR,":[181,190],"1.03;":[182],"1.01-1.05;":[185],"<":[187,196],".01;":[188],"1.04;":[191],"1.02-1.07;":[194],".01),":[197],"although":[198],"only":[205,325],"noted":[206],"failure.":[215,340],"CONCLUSIONS:":[216],"level":[219],"high-risk":[224],"patients":[225,301],"risk.":[238,261],"In":[239],"failure,":[250],"elevated":[252],"worse":[257],"LAY":[262],"SUMMARY:":[263],"This":[264],"investigates":[266],"prostate-specific":[269],"antigen":[270],"(PSA)":[271],"provide":[284],"mutually":[285],"exclusive":[286],"overlapping":[288],"information":[290],"following":[291],"treatment":[292],"using":[305],"data":[306],"trials.":[311],"It":[312],"found":[314,326],"that":[315],"provided":[317],"information;":[319],"however,":[320],"be":[328]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-04-13T00:00:00"}