{"id":"https://openalex.org/W31408297","doi":null,"title":"Helicobacter pylori detection: a quality and cost analysis.","display_name":"Helicobacter pylori detection: a quality and cost analysis.","publication_year":1993,"publication_date":"1993-05-01","ids":{"openalex":"https://openalex.org/W31408297","mag":"31408297","pmid":"https://pubmed.ncbi.nlm.nih.gov/7683175"},"language":"en","primary_location":{"id":"pmid:7683175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7683175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017452010","display_name":"Byron E. Kolts","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I61515104","display_name":"University of Florida Health Science Center","ror":"https://ror.org/0419bgt07","country_code":"US","type":"education","lineage":["https://openalex.org/I61515104"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B E Kolts","raw_affiliation_strings":["Department of Medicine, University of Florida Health Science Center, Jacksonville"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Florida Health Science Center, Jacksonville","institution_ids":["https://openalex.org/I61515104"]}]},{"author_position":"middle","author":{"id":null,"display_name":"B Joseph","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Joseph","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109658970","display_name":"Sami R. Achem","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S R Achem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"T Bianchi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Bianchi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"C Monteiro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Monteiro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":7.2283,"has_fulltext":false,"cited_by_count":82,"citation_normalized_percentile":{"value":0.97439876,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"88","issue":"5","first_page":"650","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/helicobacter-pylori","display_name":"Helicobacter pylori","score":0.9449999928474426},{"id":"https://openalex.org/keywords/histopathological-diagnosis","display_name":"histopathological diagnosis","score":0.5979999899864197},{"id":"https://openalex.org/keywords/h-e-staining","display_name":"H&E staining","score":0.6669999957084656},{"id":"https://openalex.org/keywords/giemsa-staining","display_name":"Giemsa staining","score":0.9929999709129333},{"id":"https://openalex.org/keywords/rapid-urease-test","display_name":"rapid urease test","score":0.9860000014305115},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.9350000023841858},{"id":"https://openalex.org/keywords/pathologist-experience","display_name":"pathologist experience","score":0.8569999933242798},{"id":"https://openalex.org/keywords/turnaround-time","display_name":"turnaround time","score":0.8870000243186951},{"id":"https://openalex.org/keywords/diagnostic-costs","display_name":"diagnostic costs","score":0.7839999794960022},{"id":"https://openalex.org/keywords/endoscopic-biopsy","display_name":"endoscopic biopsy","score":0.843999981880188}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9032222032546997},{"id":"https://openalex.org/C2781294515","wikidata":"https://www.wikidata.org/wiki/Q2733470","display_name":"Stain","level":3,"score":0.7889610528945923},{"id":"https://openalex.org/C154488023","wikidata":"https://www.wikidata.org/wiki/Q1412684","display_name":"Giemsa stain","level":2,"score":0.718779444694519},{"id":"https://openalex.org/C2776409635","wikidata":"https://www.wikidata.org/wiki/Q180556","display_name":"Helicobacter pylori","level":2,"score":0.5724233388900757},{"id":"https://openalex.org/C125473707","wikidata":"https://www.wikidata.org/wiki/Q9914","display_name":"H&E stain","level":3,"score":0.5703526139259338},{"id":"https://openalex.org/C3020132585","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic accuracy","level":2,"score":0.5473359823226929},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5395521521568298},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.44537830352783203},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.4299984574317932},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2841566205024719},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2570291757583618}],"mesh":[{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003365","descriptor_name":"Costs and Cost Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011706","descriptor_name":"Pyloric Antrum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011786","descriptor_name":"Quality Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013194","descriptor_name":"Staining and Labeling","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016480","descriptor_name":"Helicobacter pylori","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000191","qualifier_name":"economics","is_major_topic":true},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:7683175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7683175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Comparative Study"},{"id":"mag:31408297","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7683175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7106142026","https://openalex.org/W2157873322","https://openalex.org/W2049196519","https://openalex.org/W2233986276","https://openalex.org/W2075494372","https://openalex.org/W4224880065","https://openalex.org/W3212752248","https://openalex.org/W2535861064","https://openalex.org/W1975713397","https://openalex.org/W6912894951"],"abstract_inverted_index":{"Histopathologic":[0],"interpretation":[1],"of":[2,22,30,38,48,60,79,121,166,280],"hematoxylin":[3],"and":[4,25,58,71,77,96,104,131,164,176,200,270],"eosin":[5],"(H&E)-stained":[6],"endoscopic":[7],"biopsies":[8],"is":[9,251],"a":[10,39,92,119,252,267],"common":[11,253],"method":[12,163],"for":[13,108,129,274],"identifying":[14,84,183],"Helicobacter":[15],"pylori.":[16,282],"Few":[17],"studies":[18],"report":[19],"the":[20,35,46,55,61,64,68,72,75,98,115,138,147,155,160,167,186,198,213,218,233,278],"accuracy":[21],"this":[23,49],"method,":[24],"none":[26],"have":[27],"compared":[28,90],"costs":[29],"other":[31,122],"diagnostic":[32,44,110,139],"methods.":[33],"In":[34],"clinical":[36],"setting":[37],"community":[40],"hospital":[41],"using":[42],"standard":[43,140],"techniques,":[45],"purpose":[47],"study":[50],"were":[51,125,135,172,179],"to":[52,100,127,212,246,259],"determine":[53],"1)":[54],"comparative":[56],"sensitivities":[57],"specificities":[59],"H&E":[62,88,151,214,242,275],"stain,":[63,67,70],"Warthin-Starry":[65],"silver":[66,116,133,175,187,199],"Giemsa":[69,177,201],"CLOtest;":[73],"2)":[74],"sensitivity":[76,211],"specificity":[78],"an":[80,261],"\"experienced\"":[81,219],"pathologist":[82,227],"in":[83,141,182,210,236,277],"H.":[85,184,248,281],"pylori":[86],"by":[87,114,154,217],"stains,":[89,202],"with":[91,146],"rotating":[93,156,234],"pathology":[94,157],"faculty;":[95],"3)":[97],"time":[99],"diagnosis":[101],"(turnaround":[102],"time)":[103],"current":[105],"patient":[106],"charges":[107],"each":[109],"method.":[111],"Bacterial":[112],"identification":[113,279],"stain":[117,152,188,215],"(or":[118],"combination":[120],"tests":[123,170],"which":[124,250],"likely":[126],"compensate":[128],"false-positive":[130],"false-negative":[132],"stains)":[134],"used":[136,245],"as":[137],"evaluating":[142,237],"94":[143],"consecutive":[144],"cases":[145],"following":[148],"results:":[149],"The":[150,174,192,264],"interpreted":[153],"staff":[158],"was":[159,189,194,204,208,222,228,266],"least":[161,168],"sensitive":[162,181,196,231],"one":[165],"specific":[169],"that":[171],"studied.":[173],"stains":[178,243,276],"equally":[180,205],"pylori;":[185],"more":[190,223,230],"specific.":[191,206,224],"CLOtest":[193,207,265],"less":[195],"than":[197,232],"but":[203,221],"similar":[209],"examined":[216],"pathologist,":[220],"An":[225],"experienced":[226,262],"significantly":[229],"pathologists":[235],"H&E-stained":[238],"slides.":[239],"Therefore,":[240],"if":[241],"are":[244],"identify":[247],"pylori,":[249],"practice,":[254],"it":[255],"may":[256],"be":[257],"advantageous":[258],"use":[260],"pathologist.":[263],"simple,":[268],"rapid,":[269],"cost":[271],"effective":[272],"substitute":[273]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}