{"id":"https://openalex.org/W3140696602","doi":"https://doi.org/10.1201/9780429439964-37","title":"Models of Human Cancer","display_name":"Models of Human Cancer","publication_year":2021,"publication_date":"2021-03-26","ids":{"openalex":"https://openalex.org/W3140696602","doi":"https://doi.org/10.1201/9780429439964-37","mag":"3140696602"},"language":"en","primary_location":{"id":"doi:10.1201/9780429439964-37","doi":"https://doi.org/10.1201/9780429439964-37","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9780429439964-37","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Laboratory Animal Science","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W3141624830","display_name":"Handbook of Laboratory Animal Science"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111699144","display_name":"Lezlee Coghlan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lezlee G. Coghlan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5009933957","display_name":"Fernando J. Benavides","orcid":"https://orcid.org/0000-0003-1275-4320","observed_orcids":["https://orcid.org/0000-0003-1275-4320"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fernando J. Benavides","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6045,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.7852085,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"839","last_page":"896"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11149","display_name":"Veterinary Oncology Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/animal-models-of-cancer","display_name":"animal models of cancer","score":0.9290000200271606},{"id":"https://openalex.org/keywords/experimental-tumor-model","display_name":"experimental tumor model","score":0.4690000116825104},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.6100000143051147},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.9010000228881836},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.5590000152587891},{"id":"https://openalex.org/keywords/rodent-models","display_name":"rodent models","score":0.5389999747276306},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.7620000243186951},{"id":"https://openalex.org/keywords/squamous-cell-carcinoma","display_name":"squamous cell carcinoma","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5548059344291687},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37556734681129456},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15056908130645752}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1201/9780429439964-37","doi":"https://doi.org/10.1201/9780429439964-37","is_oa":false,"landing_page_url":"https://doi.org/10.1201/9780429439964-37","pdf_url":null,"source":{"id":"https://openalex.org/S4306463075","display_name":"CRC Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320584","host_organization_name":"CRC Press","host_organization_lineage":["https://openalex.org/P4310320584","https://openalex.org/P4310320547"],"host_organization_lineage_names":["CRC Press","Taylor & Francis"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Laboratory Animal Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2139659329"],"related_works":["https://openalex.org/W4318617998","https://openalex.org/W7030090433","https://openalex.org/W4388298683","https://openalex.org/W3011500700","https://openalex.org/W2013713832","https://openalex.org/W999810013","https://openalex.org/W4288471792","https://openalex.org/W2016828026","https://openalex.org/W4205575627","https://openalex.org/W2771292441"],"abstract_inverted_index":{"In":[0,96],"1918,":[1],"K.":[2,5],"Yamagiwa":[3],"and":[4,38,70],"Ickikawa":[6],"produced":[7],"the":[8,26,39,78,105],"first":[9],"inducible":[10],"animal":[11,36,50,64,83,112,128],"model":[12,113],"of":[13,21,33,107,127,144],"cancer,":[14,120],"causing":[15],"squamous":[16],"cell":[17],"carcinoma":[18],"via":[19],"application":[20],"coal":[22],"tar":[23],"mixtures":[24],"to":[25,45,56,72],"rabbit":[27],"ear":[28],"There":[29,133],"are":[30,43,89,134],"varying":[31],"degrees":[32],"similarity":[34],"between":[35],"models":[37,51,91,129,143],"human":[40,86,93,145],"conditions":[41],"they":[42],"used":[44,81],"represent.":[46],"To":[47],"be":[48,53,57],"practical,":[49],"should":[52],"small":[54],"enough":[55],"housed":[58],"at":[59],"reasonable":[60],"cost":[61],"in":[62,114],"standard":[63],"facilities,":[65],"easily":[66],"handled":[67],"by":[68],"investigators,":[69],"shipped":[71],"other":[73],"investigators.":[74],"The":[75],"mouse":[76],"is":[77],"most":[79],"commonly":[80],"experimental":[82],"for":[84,92,130],"modeling":[85],"cancer.":[87,95,146],"Rats":[88],"effective":[90],"breast":[94],"recent":[97],"years,":[98],"a":[99,110,135],"new":[100],"rodent":[101],"species":[102],"has":[103],"become":[104],"focus":[106],"attention":[108],"as":[109],"potential":[111],"cancer":[115,131],"research.":[116,132],"Companion":[117],"animals":[118],"with":[119],"particularly":[121],"dogs,":[122],"represent":[123],"an":[124],"emerging":[125],"source":[126],"few":[136],"species-specific":[137],"cancers":[138],"that":[139],"may":[140],"provide":[141],"useful":[142]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2021-04-13T00:00:00"}