{"id":"https://openalex.org/W3140174065","doi":"https://doi.org/10.2967/jnmt.120.258632","title":"Interobserver Agreement in the Diagnosis of Parkinson Disease with Cardiac123I-Metaiodobenzylguanidine Scintigraphy","display_name":"Interobserver Agreement in the Diagnosis of Parkinson Disease with Cardiac123I-Metaiodobenzylguanidine Scintigraphy","publication_year":2021,"publication_date":"2021-04-05","ids":{"openalex":"https://openalex.org/W3140174065","doi":"https://doi.org/10.2967/jnmt.120.258632","mag":"3140174065","pmid":"https://pubmed.ncbi.nlm.nih.gov/33820859"},"language":"en","primary_location":{"id":"doi:10.2967/jnmt.120.258632","doi":"https://doi.org/10.2967/jnmt.120.258632","is_oa":true,"landing_page_url":"https://doi.org/10.2967/jnmt.120.258632","pdf_url":"https://tech.snmjournals.org/content/jnmt/49/3/262.full.pdf","source":{"id":"https://openalex.org/S139240842","display_name":"Journal of Nuclear Medicine Technology","issn_l":"0091-4916","issn":["0091-4916","1535-5675"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315767","host_organization_name":"Society of Nuclear Medicine and Molecular Imaging","host_organization_lineage":["https://openalex.org/P4310315767"],"host_organization_lineage_names":["Society of Nuclear Medicine and Molecular Imaging"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Nuclear Medicine Technology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://tech.snmjournals.org/content/jnmt/49/3/262.full.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091390669","display_name":"Robert W. Foley","orcid":"https://orcid.org/0000-0002-5457-2392","observed_orcids":["https://orcid.org/0000-0002-5457-2392"]},"institutions":[{"id":"https://openalex.org/I2800549715","display_name":"Royal United Hospital","ror":"https://ror.org/00a858n67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"id":"https://openalex.org/I4210161895","display_name":"Royal United Hospital Bath NHS Trust","ror":"https://ror.org/058x7dy48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161895"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert W. Foley","raw_affiliation_strings":["Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and rwjfoley@gmail.com","Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and rwjfoley@gmail.com","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087612550","display_name":"Stewart Redman","orcid":"https://orcid.org/0000-0002-4438-4144","observed_orcids":["https://orcid.org/0000-0002-4438-4144"]},"institutions":[{"id":"https://openalex.org/I2800549715","display_name":"Royal United Hospital","ror":"https://ror.org/00a858n67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"id":"https://openalex.org/I4210161895","display_name":"Royal United Hospital Bath NHS Trust","ror":"https://ror.org/058x7dy48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161895"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stewart L. Redman","raw_affiliation_strings":["Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and","Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086555415","display_name":"Isabel Laurence","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1307034911","display_name":"North Bristol NHS Trust","ror":"https://ror.org/036x6gt55","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1307034911","https://openalex.org/I4405276282"]},{"id":"https://openalex.org/I2801253297","display_name":"Southmead Hospital","ror":"https://ror.org/05d576879","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801253297","https://openalex.org/I4405276282"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Isabel J. Laurence","raw_affiliation_strings":["Department of Radiology, Southmead Hospital, North Bristol NHS Trust, North Bristol, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Southmead Hospital, North Bristol NHS Trust, North Bristol, United Kingdom","institution_ids":["https://openalex.org/I1307034911","https://openalex.org/I2801253297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015406403","display_name":"Richard Graham","orcid":"https://orcid.org/0000-0001-5124-2630","observed_orcids":["https://orcid.org/0000-0001-5124-2630"]},"institutions":[{"id":"https://openalex.org/I2800549715","display_name":"Royal United Hospital","ror":"https://ror.org/00a858n67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"id":"https://openalex.org/I4210161895","display_name":"Royal United Hospital Bath NHS Trust","ror":"https://ror.org/058x7dy48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161895"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard N. Graham","raw_affiliation_strings":["Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and","Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]}]},{"author_position":"last","author":{"id":null,"display_name":"David Little","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800549715","display_name":"Royal United Hospital","ror":"https://ror.org/00a858n67","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"id":"https://openalex.org/I4210161895","display_name":"Royal United Hospital Bath NHS Trust","ror":"https://ror.org/058x7dy48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161895"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David Little","raw_affiliation_strings":["Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and","Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom; and","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]},{"raw_affiliation_string":"Department of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom","institution_ids":["https://openalex.org/I2800549715","https://openalex.org/I4210161895"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"49","issue":"3","first_page":"262","last_page":"264"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.30300000309944153,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.30300000309944153,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.25760000944137573,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.125900000333786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9599999785423279},{"id":"https://openalex.org/keywords/123i-mibg-scintigraphy","display_name":"123I-MIBG scintigraphy","score":0.859000027179718},{"id":"https://openalex.org/keywords/cardiac-sympathetic-imaging","display_name":"cardiac sympathetic imaging","score":0.5429999828338623},{"id":"https://openalex.org/keywords/interobserver-agreement","display_name":"interobserver agreement","score":0.984000027179718},{"id":"https://openalex.org/keywords/heart-to-mediastinum-ratio","display_name":"heart-to-mediastinum ratio","score":0.9919999837875366},{"id":"https://openalex.org/keywords/visual-interpretation","display_name":"visual interpretation","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.7549320459365845},{"id":"https://openalex.org/C2779200277","wikidata":"https://www.wikidata.org/wiki/Q1164658","display_name":"Collimator","level":2,"score":0.7460584044456482},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6475013494491577},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.5800447463989258},{"id":"https://openalex.org/C2779190346","wikidata":"https://www.wikidata.org/wiki/Q3801335","display_name":"Iodine-123","level":2,"score":0.47955724596977234},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3597937226295471},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22482240200042725},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011877","descriptor_name":"Radionuclide Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015588","descriptor_name":"Observer Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019275","descriptor_name":"Radiopharmaceuticals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019797","descriptor_name":"3-Iodobenzylguanidine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2967/jnmt.120.258632","doi":"https://doi.org/10.2967/jnmt.120.258632","is_oa":true,"landing_page_url":"https://doi.org/10.2967/jnmt.120.258632","pdf_url":"https://tech.snmjournals.org/content/jnmt/49/3/262.full.pdf","source":{"id":"https://openalex.org/S139240842","display_name":"Journal of Nuclear Medicine Technology","issn_l":"0091-4916","issn":["0091-4916","1535-5675"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315767","host_organization_name":"Society of Nuclear Medicine and Molecular Imaging","host_organization_lineage":["https://openalex.org/P4310315767"],"host_organization_lineage_names":["Society of Nuclear Medicine and Molecular Imaging"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Nuclear Medicine Technology","raw_type":"journal-article"},{"id":"pmid:33820859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33820859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of nuclear medicine technology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2967/jnmt.120.258632","doi":"https://doi.org/10.2967/jnmt.120.258632","is_oa":true,"landing_page_url":"https://doi.org/10.2967/jnmt.120.258632","pdf_url":"https://tech.snmjournals.org/content/jnmt/49/3/262.full.pdf","source":{"id":"https://openalex.org/S139240842","display_name":"Journal of Nuclear Medicine Technology","issn_l":"0091-4916","issn":["0091-4916","1535-5675"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315767","host_organization_name":"Society of Nuclear Medicine and Molecular Imaging","host_organization_lineage":["https://openalex.org/P4310315767"],"host_organization_lineage_names":["Society of Nuclear Medicine and Molecular Imaging"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Nuclear Medicine Technology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3140174065.pdf","grobid_xml":"https://content.openalex.org/works/W3140174065.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1855500719","https://openalex.org/W2012445753","https://openalex.org/W2029067902","https://openalex.org/W2041402435","https://openalex.org/W2112455323","https://openalex.org/W2124473300","https://openalex.org/W2134084374","https://openalex.org/W2157432060","https://openalex.org/W2281923782","https://openalex.org/W2408034554","https://openalex.org/W2473280862","https://openalex.org/W2569094787","https://openalex.org/W2944315768","https://openalex.org/W2963767074","https://openalex.org/W2964084342","https://openalex.org/W2974051306","https://openalex.org/W6639229424"],"related_works":["https://openalex.org/W2046258293","https://openalex.org/W4310536837","https://openalex.org/W2090940335","https://openalex.org/W2970471207","https://openalex.org/W2486716678","https://openalex.org/W2946772170","https://openalex.org/W2111292139","https://openalex.org/W2061846644","https://openalex.org/W2766964359","https://openalex.org/W2522928295"],"abstract_inverted_index":{"The":[0,29,69,128],"aim":[1],"of":[2,11,16,38,55,72,86,130],"this":[3],"study":[4],"was":[5,33,47,80],"to":[6,99],"analyze":[7],"the":[8,36,53,84,87],"interobserver":[9,148],"agreement":[10,82,120],"visual":[12,76,141],"and":[13,51,144],"quantitative":[14],"assessment":[15,142],"cardiac":[17],"123I-metaiodobenzylguanidine":[18],"scintigraphy.":[19],"Methods:":[20],"Planar":[21],"images":[22],"were":[23,61],"acquired":[24],"using":[25,42],"a":[26,39,43,100],"low-energy":[27,40,136],"collimator.":[28],"heart-to-mediastinum":[30],"(HM)":[31],"ratio":[32],"adjusted":[34,56,134],"for":[35,135,146],"use":[37,129,138],"collimator,":[41],"published":[44],"formula.":[45],"Interpretation":[46],"undertaken":[48],"both":[49],"visually":[50],"after":[52],"addition":[54],"HM":[57,96,132],"ratios.":[58],"Image":[59],"findings":[60],"classified":[62],"as":[63],"normal,":[64],"abnormal,":[65],"or":[66],"borderline.":[67],"Results:":[68],"cohort":[70],"consisted":[71],"10":[73],"patients.":[74],"On":[75],"interpretation":[77,85],"only,":[78],"there":[79],"strong":[81],"on":[83,140],"scan":[88],"(\u03ba":[89,121],"=":[90,110,122],"0.82,":[91],"P":[92,109,124],"<":[93,125],"0.01).":[94,126],"Adjusted":[95],"ratios":[97,105,133],"led":[98],"significant":[101],"increase":[102],"in":[103,115,118],"mean":[104],"(1.79":[106],"vs.":[107],"1.36,":[108],"0.02)":[111],"and,":[112],"when":[113],"utilized":[114],"reporting,":[116],"resulted":[117],"perfect":[119],"1.0,":[123],"Conclusion:":[127],"quantified":[131],"collimator":[137],"improves":[139],"alone":[143],"allowed":[145],"excellent":[147],"agreement.":[149]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-04-13T00:00:00"}