{"id":"https://openalex.org/W3139944652","doi":null,"title":"Nasal drug delivery system - an overview","display_name":"Nasal drug delivery system - an overview","publication_year":2010,"publication_date":"2010-10-22","ids":{"openalex":"https://openalex.org/W3139944652","mag":"3139944652"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:50bfa27472d2414493ab76d736db9cf4","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/50bfa27472d2414493ab76d736db9cf4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Research in Pharmaceutical Sciences, Vol 1, Iss 4, Pp 454-465 (2010)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://pharmascope.org/ijrps/article/download/920/866","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"M Alagusundaram","orcid":"https://orcid.org/0000-0002-8896-8643","observed_orcids":["https://orcid.org/0000-0002-8896-8643"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Alagusundaram","raw_affiliation_strings":["Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India"],"raw_orcid":"https://orcid.org/0000-0002-8896-8643","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036712906","display_name":"B. Chengaiah","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Chengaiah","raw_affiliation_strings":["Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102821272","display_name":"K Gnanaprakash","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Gnanaprakash","raw_affiliation_strings":["Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051011985","display_name":"Sundarapandian Ramkanth","orcid":"https://orcid.org/0000-0002-2987-1526","observed_orcids":["https://orcid.org/0000-0002-2987-1526"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Ramkanth","raw_affiliation_strings":["Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111464076","display_name":"C. Madhusudhana Chetty","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Madhusudhana Chetty","raw_affiliation_strings":["Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Annamacharya College of Pharmacy, New Boyanapalli, Rajampet\u2013 516 126,  Kadapa, Andhra Pradesh, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048206340","display_name":"D Dhachinamoorthi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Dhachinamoorthi","raw_affiliation_strings":["QIS College of pharmacy, Ongole, Andhra Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"QIS College of pharmacy, Ongole, Andhra Pradesh, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4425,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.55129012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"1","issue":"4","first_page":"454","last_page":"465"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intranasal-drug-delivery","display_name":"intranasal drug delivery","score":0.9929999709129333},{"id":"https://openalex.org/keywords/nasal-absorption","display_name":"nasal absorption","score":0.8930000066757202},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.7419999837875366},{"id":"https://openalex.org/keywords/nasal-vaccine","display_name":"nasal vaccine","score":0.4339999854564667},{"id":"https://openalex.org/keywords/dna-vaccine","display_name":"DNA vaccine","score":0.8330000042915344},{"id":"https://openalex.org/keywords/protein-and-peptide-delivery","display_name":"protein and peptide delivery","score":0.7770000100135803},{"id":"https://openalex.org/keywords/brain-targeting","display_name":"brain targeting","score":0.44699999690055847},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.8209999799728394},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/first-pass-metabolism-avoidance","display_name":"first-pass metabolism avoidance","score":0.6610000133514404},{"id":"https://openalex.org/keywords/nasal-permeability","display_name":"nasal permeability","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C85663871","wikidata":"https://www.wikidata.org/wiki/Q6966562","display_name":"Nasal administration","level":2,"score":0.7416824102401733},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.6940097212791443},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6820945739746094},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5994164347648621},{"id":"https://openalex.org/C2778801703","wikidata":"https://www.wikidata.org/wiki/Q156104","display_name":"Nasal cavity","level":2,"score":0.5721110105514526},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5413349866867065},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5218290686607361},{"id":"https://openalex.org/C59377437","wikidata":"https://www.wikidata.org/wiki/Q515471","display_name":"Mucous membrane of nose","level":2,"score":0.41632360219955444},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.23262956738471985},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13982436060905457},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.10536235570907593},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.08348926901817322}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:doaj.org/article:50bfa27472d2414493ab76d736db9cf4","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/50bfa27472d2414493ab76d736db9cf4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Research in Pharmaceutical Sciences, Vol 1, Iss 4, Pp 454-465 (2010)","raw_type":"article"},{"id":"mag:3139944652","doi":null,"is_oa":true,"landing_page_url":"https://pharmascope.org/ijrps/article/download/920/866","pdf_url":null,"source":{"id":"https://openalex.org/S2764443815","display_name":"International Journal of Research in Pharmaceutical Sciences","issn_l":"0975-7538","issn":["0975-7538"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4323283528","host_organization_name":"Pharmascope Foundation","host_organization_lineage":["https://openalex.org/P4323283528"],"host_organization_lineage_names":["Pharmascope Foundation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Research in Pharmaceutical Sciences","raw_type":null}],"best_oa_location":{"id":"mag:3139944652","doi":null,"is_oa":true,"landing_page_url":"https://pharmascope.org/ijrps/article/download/920/866","pdf_url":null,"source":{"id":"https://openalex.org/S2764443815","display_name":"International Journal of Research in Pharmaceutical Sciences","issn_l":"0975-7538","issn":["0975-7538"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","poland-20"],"host_organization":"https://openalex.org/P4323283528","host_organization_name":"Pharmascope Foundation","host_organization_lineage":["https://openalex.org/P4323283528"],"host_organization_lineage_names":["Pharmascope Foundation"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Research in Pharmaceutical Sciences","raw_type":null},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6911299747","https://openalex.org/W4390516205","https://openalex.org/W2052526822","https://openalex.org/W7220625340","https://openalex.org/W2188300261","https://openalex.org/W2126446846","https://openalex.org/W2313247510","https://openalex.org/W2409360738","https://openalex.org/W2156946852","https://openalex.org/W4405263106"],"abstract_inverted_index":{"The":[0],"use":[1],"of":[2,9,38,43,54,66,97,109,152],"the":[3,7,30,76,79,100,107],"nasal":[4,39,64,134,141,146,153],"route":[5],"for":[6,51,63,106,118],"delivery":[8,53,61,108,155],"challenging":[10],"drugs":[11,77,98],"such":[12],"as":[13],"small":[14],"polar":[15],"molecules,":[16],"vaccines,":[17],"hormones,":[18,115],"peptides":[19],"and":[20,41,69,150],"proteins":[21],"has":[22],"created":[23],"much":[24],"interest":[25],"in":[26,145],"nowadays.":[27],"Due":[28],"to":[29,74,78,99,121,129,139],"high":[31,33],"permeability,":[32],"vasculature,":[34],"low":[35],"enzymatic":[36],"environment":[37],"cavity":[40],"avoidance":[42],"hepatic":[44],"first":[45],"pass":[46],"metabolism":[47],"are":[48,72],"well":[49,104],"suitable":[50,105],"systemic":[52],"drug":[55,60,154],"molecule":[56],"via":[57],"nose.":[58],"Many":[59],"devices":[62],"application":[65],"liquid,":[67],"semisolid":[68],"solid":[70],"formulation":[71],"investigated":[73],"deliver":[75],"treat":[80],"most":[81],"crisis":[82],"CNS":[83],"diseases":[84],"(i.e.,":[85],"Parkinson\u2019s":[86],"disease,":[87],"Alzheimer\u2019s":[88],"disease)":[89],"because":[90],"it":[91],"requires":[92],"rapid":[93],"and/or":[94],"specific":[95],"targeting":[96],"brain.":[101],"It":[102],"is":[103],"biotechnological":[110],"products":[111],"like":[112],"proteins,":[113],"peptides,":[114],"DNA":[116,119],"plasmids":[117],"vaccines":[120],"give":[122],"enhanced":[123],"bioavailability.":[124],"This":[125],"review":[126],"sets":[127],"out":[128],"discuss":[130],"some":[131],"factors":[132],"affecting":[133],"absorption,":[135,142],"bioavailability":[136],"barriers,":[137],"strategies":[138],"improve":[140],"new":[143],"developments":[144],"dosage":[147],"form":[148],"design":[149],"applications":[151],"system.":[156]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2021-04-13T00:00:00"}