{"id":"https://openalex.org/W3138904387","doi":"https://doi.org/10.1177/20420188211000243","title":"Effect of sodium-glucose cotransporter 2 inhibitor in patients with non-alcoholic fatty liver disease and type 2 diabetes mellitus: a propensity score-matched analysis of real-world data","display_name":"Effect of sodium-glucose cotransporter 2 inhibitor in patients with non-alcoholic fatty liver disease and type 2 diabetes mellitus: a propensity score-matched analysis of real-world data","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3138904387","doi":"https://doi.org/10.1177/20420188211000243","mag":"3138904387","pmid":"https://pubmed.ncbi.nlm.nih.gov/33815743","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7989116"},"language":"en","primary_location":{"id":"doi:10.1177/20420188211000243","doi":"https://doi.org/10.1177/20420188211000243","is_oa":true,"landing_page_url":"https://doi.org/10.1177/20420188211000243","pdf_url":null,"source":{"id":"https://openalex.org/S114986954","display_name":"Therapeutic Advances in Endocrinology and Metabolism","issn_l":"2042-0188","issn":["2042-0188","2042-0196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","ki-jl-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic Advances in Endocrinology and Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1177/20420188211000243","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110757059","display_name":"Taeang Arai","orcid":"https://orcid.org/0009-0008-5817-1845","observed_orcids":["https://orcid.org/0009-0008-5817-1845"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taeang Arai","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080709934","display_name":"Masanori Atsukawa","orcid":"https://orcid.org/0000-0003-3374-7111","observed_orcids":["https://orcid.org/0000-0003-3374-7111"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Masanori Atsukawa","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, 1-1-5, Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086743926","display_name":"Akihito Tsubota","orcid":"https://orcid.org/0000-0001-6860-0326","observed_orcids":["https://orcid.org/0000-0001-6860-0326"]},"institutions":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akihito Tsubota","raw_affiliation_strings":["Core Research Facilities for Basic Science, Research Center for Medical Sciences, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Core Research Facilities for Basic Science, Research Center for Medical Sciences, The Jikei University School of Medicine, Minato-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I115498069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051397464","display_name":"Shigeru Mikami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13045471","display_name":"Kikkoman (Japan)","ror":"https://ror.org/00z0d6447","country_code":"JP","type":"company","lineage":["https://openalex.org/I13045471"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeru Mikami","raw_affiliation_strings":["Division of Gastroenterology, Department of Internal Medicine, Kikkoman General Hospital, Miyazaki Noda, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Department of Internal Medicine, Kikkoman General Hospital, Miyazaki Noda, Japan","institution_ids":["https://openalex.org/I13045471"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057771677","display_name":"Hiroki Ono","orcid":"https://orcid.org/0009-0008-2963-5743","observed_orcids":["https://orcid.org/0009-0008-2963-5743","https://orcid.org/0000-0003-3723-2967"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroki Ono","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083034464","display_name":"Tadamichi Kawano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tadamichi Kawano","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yuji Yoshida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162733","display_name":"Chiba Hokusou Hospital","ror":"https://ror.org/050adm910","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210162733"]},{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuji Yoshida","raw_affiliation_strings":["Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan","institution_ids":["https://openalex.org/I4210162733","https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084516430","display_name":"Tomohide Tanabe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomohide Tanabe","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049568375","display_name":"Tomomi Okubo","orcid":"https://orcid.org/0000-0003-1244-4736","observed_orcids":["https://orcid.org/0000-0003-1244-4736"]},"institutions":[{"id":"https://openalex.org/I4210162733","display_name":"Chiba Hokusou Hospital","ror":"https://ror.org/050adm910","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210162733"]},{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomomi Okubo","raw_affiliation_strings":["Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan","institution_ids":["https://openalex.org/I4210162733","https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051628501","display_name":"Korenobu Hayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162733","display_name":"Chiba Hokusou Hospital","ror":"https://ror.org/050adm910","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210162733"]},{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Korenobu Hayama","raw_affiliation_strings":["Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan","institution_ids":["https://openalex.org/I4210162733","https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004997283","display_name":"Ai Nakagawa\u2010Iwashita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ai Nakagawa-Iwashita","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009103376","display_name":"Norio Itokawa","orcid":"https://orcid.org/0009-0002-2390-6692","observed_orcids":["https://orcid.org/0009-0002-2390-6692"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norio Itokawa","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000519458","display_name":"Chisa Kondo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Chisa Kondo","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051824895","display_name":"Keiko Kaneko","orcid":"https://orcid.org/0009-0003-4778-2919","observed_orcids":["https://orcid.org/0009-0003-4778-2919"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiko Kaneko","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055696100","display_name":"Naoya Emoto","orcid":"https://orcid.org/0000-0003-2026-4057","observed_orcids":["https://orcid.org/0000-0003-2026-4057"]},"institutions":[{"id":"https://openalex.org/I4210162733","display_name":"Chiba Hokusou Hospital","ror":"https://ror.org/050adm910","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210162733"]},{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoya Emoto","raw_affiliation_strings":["Division of Endocrinology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan","institution_ids":["https://openalex.org/I4210162733","https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080998573","display_name":"Mototsugu Nagao","orcid":"https://orcid.org/0000-0001-6880-5161","observed_orcids":["https://orcid.org/0000-0001-6880-5161"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mototsugu Nagao","raw_affiliation_strings":["Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0001-6880-5161","affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031628301","display_name":"Kyoko Inagaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kyoko Inagaki","raw_affiliation_strings":["Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021519220","display_name":"Izumi Fukuda","orcid":"https://orcid.org/0000-0003-0772-3837","observed_orcids":["https://orcid.org/0000-0003-0772-3837"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Izumi Fukuda","raw_affiliation_strings":["Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002368893","display_name":"Hitoshi Sugihara","orcid":"https://orcid.org/0000-0003-2194-5743","observed_orcids":["https://orcid.org/0000-0003-2194-5743"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Sugihara","raw_affiliation_strings":["Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Endocrinology, Diabetes and Metabolism, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058841198","display_name":"Katsuhiko Iwakiri","orcid":"https://orcid.org/0000-0002-5558-6104","observed_orcids":["https://orcid.org/0000-0002-5558-6104"]},"institutions":[{"id":"https://openalex.org/I80188885","display_name":"Nippon Medical School","ror":"https://ror.org/00krab219","country_code":"JP","type":"education","lineage":["https://openalex.org/I80188885"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhiko Iwakiri","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, Nippon Medical School, Bunkyo-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I80188885"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5080709934"],"corresponding_institution_ids":["https://openalex.org/I80188885"],"apc_list":{"value":2400,"currency":"USD","value_usd":2400},"apc_paid":{"value":2400,"currency":"USD","value_usd":2400},"fwci":2.8174,"has_fulltext":true,"cited_by_count":31,"citation_normalized_percentile":{"value":0.92100699,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"12","issue":null,"first_page":"20420188211000243","last_page":"20420188211000243"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.7827000021934509,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.7827000021934509,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.20029999315738678,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sglt2-inhibitors","display_name":"SGLT2 inhibitors","score":0.9649999737739563},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9729999899864197},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":1.0},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.652999997138977},{"id":"https://openalex.org/keywords/transient-elastography","display_name":"transient elastography","score":0.8820000290870667},{"id":"https://openalex.org/keywords/controlled-attenuation-parameter","display_name":"controlled attenuation parameter","score":0.8330000042915344},{"id":"https://openalex.org/keywords/liver-stiffness-measurement","display_name":"liver stiffness measurement","score":0.8550000190734863},{"id":"https://openalex.org/keywords/fib-4-index","display_name":"FIB-4","score":0.8679999709129333},{"id":"https://openalex.org/keywords/oral-antidiabetic-drugs","display_name":"oral antidiabetic drugs","score":0.8840000033378601},{"id":"https://openalex.org/keywords/weight-loss","display_name":"weight loss","score":0.6940000057220459},{"id":"https://openalex.org/keywords/uric-acid","display_name":"uric acid","score":0.9520000219345093},{"id":"https://openalex.org/keywords/alanine-aminotransferase","display_name":"alanine aminotransferase","score":0.9649999737739563},{"id":"https://openalex.org/keywords/real-world-data","display_name":"real-world data","score":0.6790000200271606},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.37700000405311584}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8810359239578247},{"id":"https://openalex.org/C2780826214","wikidata":"https://www.wikidata.org/wiki/Q1324974","display_name":"Transient elastography","level":4,"score":0.7876220345497131},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.717211902141571},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.7106282711029053},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5995121598243713},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5825295448303223},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.555777370929718},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.5349477529525757},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.519124448299408},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.5188061594963074},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5153457522392273},{"id":"https://openalex.org/C17923572","wikidata":"https://www.wikidata.org/wiki/Q7250160","display_name":"Propensity score matching","level":2,"score":0.4121052026748657},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3257218301296234},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.21817949414253235},{"id":"https://openalex.org/C2994217296","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Liver fibrosis","level":3,"score":0.15883833169937134}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1177/20420188211000243","doi":"https://doi.org/10.1177/20420188211000243","is_oa":true,"landing_page_url":"https://doi.org/10.1177/20420188211000243","pdf_url":null,"source":{"id":"https://openalex.org/S114986954","display_name":"Therapeutic Advances in Endocrinology and Metabolism","issn_l":"2042-0188","issn":["2042-0188","2042-0196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","ki-jl-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic Advances in Endocrinology and Metabolism","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7989116","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7989116/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7989116/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ther Adv Endocrinol Metab","raw_type":"Text"},{"id":"pmid:33815743","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33815743","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic advances in endocrinology and metabolism","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:41d7d403604345b8b5e39f5e1539d661","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/41d7d403604345b8b5e39f5e1539d661","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Therapeutic Advances in Endocrinology and Metabolism, Vol 12 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/20420188211000243","doi":"https://doi.org/10.1177/20420188211000243","is_oa":true,"landing_page_url":"https://doi.org/10.1177/20420188211000243","pdf_url":null,"source":{"id":"https://openalex.org/S114986954","display_name":"Therapeutic Advances in Endocrinology and Metabolism","issn_l":"2042-0188","issn":["2042-0188","2042-0196"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","ki-jl-1","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Therapeutic Advances in Endocrinology and Metabolism","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G4622870910","display_name":"Elucidation of the stealth mechanism of infection chronicity by hepatitis B virus and drug discovery of inhibitory molecular targets","funder_award_id":"19K08937","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3138904387.pdf","grobid_xml":"https://content.openalex.org/works/W3138904387.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1534242660","https://openalex.org/W1623910198","https://openalex.org/W1902670387","https://openalex.org/W1946550634","https://openalex.org/W1964572117","https://openalex.org/W1969770795","https://openalex.org/W1997884202","https://openalex.org/W2017741306","https://openalex.org/W2025680761","https://openalex.org/W2035962070","https://openalex.org/W2038270027","https://openalex.org/W2047257800","https://openalex.org/W2062812115","https://openalex.org/W2088337379","https://openalex.org/W2106937897","https://openalex.org/W2130570549","https://openalex.org/W2137107263","https://openalex.org/W2204688218","https://openalex.org/W2224883440","https://openalex.org/W2282195703","https://openalex.org/W2291072797","https://openalex.org/W2302367542","https://openalex.org/W2470709274","https://openalex.org/W2512864147","https://openalex.org/W2560921027","https://openalex.org/W2582145734","https://openalex.org/W2591859981","https://openalex.org/W2621939592","https://openalex.org/W2734724639","https://openalex.org/W2737083386","https://openalex.org/W2742155329","https://openalex.org/W2743667261","https://openalex.org/W2759997926","https://openalex.org/W2761135733","https://openalex.org/W2808615577","https://openalex.org/W2884837248","https://openalex.org/W2885064594","https://openalex.org/W2890673765","https://openalex.org/W2894993577","https://openalex.org/W2895533920","https://openalex.org/W2900924712","https://openalex.org/W2912523003","https://openalex.org/W2960214239","https://openalex.org/W2962432528","https://openalex.org/W3002268034","https://openalex.org/W3011655835","https://openalex.org/W3019568499","https://openalex.org/W3036071554","https://openalex.org/W3102426258","https://openalex.org/W3122243095","https://openalex.org/W3143409077"],"related_works":["https://openalex.org/W4293547704","https://openalex.org/W4384831712","https://openalex.org/W4206429269","https://openalex.org/W4252525169","https://openalex.org/W4310069577","https://openalex.org/W4382918377","https://openalex.org/W4415591487","https://openalex.org/W3121404945","https://openalex.org/W3008837192","https://openalex.org/W3111310432"],"abstract_inverted_index":{"Background:":[0],"Although":[1],"sodium-glucose":[2],"cotransporter":[3],"2":[4,29],"inhibitors":[5],"(SGLT2-Is)":[6],"improve":[7],"not":[8,269],"only":[9,270],"glycemic":[10,271],"control":[11,272],"but":[12,273],"also":[13,274],"liver":[14,24,38,56,78,154,275],"inflammation":[15],"and":[16,27,35,60,108,153,175,222,255,278,284],"fatty":[17,23,58,276],"changes":[18,96],"in":[19,62,84,97,139,172,181,203,235,251,258,280],"patients":[20,64,86,102,170,281],"with":[21,65,87,192,282],"non-alcoholic":[22],"disease":[25],"(NAFLD)":[26],"type":[28],"diabetes":[30],"mellitus":[31],"(T2DM),":[32],"its":[33],"sustainability":[34],"effect":[36],"on":[37,55,75],"fibrosis":[39,61,79,279],"have":[40],"remained":[41],"unclear.":[42],"The":[43,132,233],"current":[44],"study":[45,69],"aimed":[46],"to":[47,126,147,290],"clarify":[48],"the":[49,71,173,187,193,196,252,259],"effects":[50,72],"of":[51,73],"48-week":[52],"SGLT2-I":[53,74,91,104,106,133,174,197,253],"therapy":[54],"inflammation,":[57],"changes,":[59],"NAFLD":[63,88,283],"T2DM.":[66],"Methods:":[67],"This":[68],"evaluated":[70],"NAFLD,":[76],"including":[77],"assessed":[80],"via":[81],"transient":[82],"elastography,":[83],"56":[85],"who":[89],"received":[90],"for":[92,128,163],"48":[93],"weeks.":[94],"Moreover,":[95],"each":[98,171],"clinical":[99],"parameter":[100,142],"between":[101,186],"receiving":[103,110],"(the":[105,116],"group)":[107,118],"those":[109],"other":[111,291],"oral":[112],"hypoglycemic":[113],"agents":[114],"(OHAs)":[115],"non-SGLT2-I":[117,176,194,260],"were":[119],"compared,":[120],"using":[121],"1:1":[122],"propensity":[123,166],"score":[124,167],"matching":[125,168],"adjust":[127],"baseline":[129,146,244],"factors.":[130],"Results:":[131],"group":[134,198,254,261],"exhibited":[135],"a":[136,200,240],"significant":[137,179,201],"decrease":[138,183,202],"controlled":[140],"attenuation":[141],"(312":[143],"dB/m":[144,149],"at":[145,150,230,245],"280":[148],"week":[151,231,246],"48)":[152],"stiffness":[155],"measurement":[156],"(9.1\u20136.7":[157],"kPa)":[158],"(":[159,206,212,218,226,262],"p":[160,207,213,219,227,263],"<":[161,208,220,264],"0.001":[162],"both).":[164],"After":[165],"(44":[169],"groups),":[177],"no":[178],"difference":[180],"HbA1c":[182],"was":[184,248],"observed":[185],"two":[188],"groups.":[189],"However,":[190],"compared":[191],"group,":[195],"showed":[199],"body":[204],"weight":[205],"0.001),":[209,221],"alanine":[210],"aminotransferase":[211],"=":[214,228],"0.02),":[215],"uric":[216],"acid":[217],"Fibrosis-4":[223],"(FIB-4)":[224],"index":[225],"0.01)":[229],"48.":[232],"improvement":[234],"FIB-4":[236],"index,":[237],"defined":[238],"as":[239],"\u2a7e10%":[241],"decline":[242],"from":[243],"48,":[247],"56.8%":[249],"(25/44)":[250],"20.5%":[256],"(9/44)":[257],"0.001).":[265],"Conclusion:":[266],"SGLT2-Is":[267],"improved":[268],"infiltration":[277],"T2DM,":[285],"suggesting":[286],"their":[287],"possible":[288],"superiority":[289],"OHAs":[292],"concerning":[293],"these":[294],"effects.":[295]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2021-03-29T00:00:00"}