{"id":"https://openalex.org/W3138765776","doi":"https://doi.org/10.1038/s41598-021-86185-3","title":"Quantitative comparison of corneal surface areas in keratoconus and normal eyes","display_name":"Quantitative comparison of corneal surface areas in keratoconus and normal eyes","publication_year":2021,"publication_date":"2021-03-25","ids":{"openalex":"https://openalex.org/W3138765776","doi":"https://doi.org/10.1038/s41598-021-86185-3","mag":"3138765776","pmid":"https://pubmed.ncbi.nlm.nih.gov/33767220","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7994394"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-021-86185-3","doi":"https://doi.org/10.1038/s41598-021-86185-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-021-86185-3","pdf_url":"https://www.nature.com/articles/s41598-021-86185-3.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-021-86185-3.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058884446","display_name":"Fran\u00e7ois-Xavier Crahay","orcid":"https://orcid.org/0000-0001-7337-8512","observed_orcids":["https://orcid.org/0000-0001-7337-8512","https://orcid.org/0000-0002-7774-1478"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]},{"id":"https://openalex.org/I4210159123","display_name":"Centre hospitalier r\u00e9gional de la Citadelle","ror":"https://ror.org/059kfmf89","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210159123"]}],"countries":["BE","FR"],"is_corresponding":false,"raw_author_name":"Fran\u00e7ois-Xavier Crahay","raw_affiliation_strings":["CHR Citadelle, Li\u00e8ge, Belgique","Rothschild Foundation Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHR Citadelle, Li\u00e8ge, Belgique","institution_ids":["https://openalex.org/I4210159123"]},{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078951438","display_name":"Guillaume Debellemani\u00e8re","orcid":"https://orcid.org/0000-0001-5265-344X","observed_orcids":["https://orcid.org/0000-0001-5265-344X"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Guillaume Debellemani\u00e8re","raw_affiliation_strings":["Rothschild Foundation Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008873608","display_name":"St\u00e9phan Tobalem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Stephan Tobalem","raw_affiliation_strings":["Rothschild Foundation Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006905385","display_name":"Wassim Ghazal","orcid":"https://orcid.org/0000-0002-3575-5249","observed_orcids":["https://orcid.org/0000-0002-3575-5249"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Wassim Ghazal","raw_affiliation_strings":["Rothschild Foundation Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065944406","display_name":"Sarah Moran","orcid":"https://orcid.org/0000-0002-3081-705X","observed_orcids":["https://orcid.org/0000-0002-3081-705X"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sarah Moran","raw_affiliation_strings":["Rothschild Foundation Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033451757","display_name":"Damien Gatinel","orcid":"https://orcid.org/0000-0001-9603-0500","observed_orcids":["https://orcid.org/0000-0001-9603-0500"]},"institutions":[{"id":"https://openalex.org/I4210090185","display_name":"H\u00f4pital Rothschild","ror":"https://ror.org/009kb8w74","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210090185","https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210127304","display_name":"Fondation de Rothschild","ror":"https://ror.org/02yfw7119","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4210127304"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Damien Gatinel","raw_affiliation_strings":["Rothschild Foundation Hospital, Paris, France. gatinel@gmail.com","Rothschild Foundation Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France. gatinel@gmail.com","institution_ids":["https://openalex.org/I4210090185"]},{"raw_affiliation_string":"Rothschild Foundation Hospital, Paris, France","institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5033451757"],"corresponding_institution_ids":["https://openalex.org/I4210090185","https://openalex.org/I4210127304"],"apc_list":{"value":1990,"currency":"USD","value_usd":1990},"apc_paid":{"value":1990,"currency":"USD","value_usd":1990},"fwci":1.2675,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.74473075,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"11","issue":"1","first_page":"6840","last_page":"6840"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10381","display_name":"Ophthalmology and Visual Impairment Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/keratoconus","display_name":"keratoconus","score":1.0},{"id":"https://openalex.org/keywords/corneal-topography","display_name":"corneal topography","score":0.9079999923706055},{"id":"https://openalex.org/keywords/corneal-thinning","display_name":"corneal thinning","score":0.7549999952316284},{"id":"https://openalex.org/keywords/corneal-steepening","display_name":"corneal steepening","score":0.7149999737739563},{"id":"https://openalex.org/keywords/amsler-krumeich-classification","display_name":"Amsler-Krumeich classification","score":0.8790000081062317},{"id":"https://openalex.org/keywords/keratoconus-severity","display_name":"keratoconus severity","score":0.9259999990463257},{"id":"https://openalex.org/keywords/corneal-diameter","display_name":"corneal diameter","score":0.7749999761581421},{"id":"https://openalex.org/keywords/corneal-astigmatism","display_name":"corneal astigmatism","score":0.6190000176429749}],"concepts":[{"id":"https://openalex.org/C2778918178","wikidata":"https://www.wikidata.org/wiki/Q611984","display_name":"Keratoconus","level":3,"score":0.9934799671173096},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7748683094978333},{"id":"https://openalex.org/C2781053140","wikidata":"https://www.wikidata.org/wiki/Q3501232","display_name":"Corneal topography","level":3,"score":0.6371474266052246},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.6237755417823792},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5628960132598877}],"mesh":[{"descriptor_ui":"D000078332","descriptor_name":"Data Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D003315","descriptor_name":"Cornea","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007640","descriptor_name":"Keratoconus","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D007640","descriptor_name":"Keratoconus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019781","descriptor_name":"Corneal Topography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41598-021-86185-3","doi":"https://doi.org/10.1038/s41598-021-86185-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-021-86185-3","pdf_url":"https://www.nature.com/articles/s41598-021-86185-3.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmid:33767220","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33767220","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7994394","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7994394/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:unige.ch:aou:unige:151834","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:151834","pdf_url":null,"source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ISSN: 2045-2322","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:unige.ch:unige:151834","doi":null,"is_oa":true,"landing_page_url":"https://archive-ouverte.unige.ch/unige:151834","pdf_url":"https://access.archive-ouverte.unige.ch/access/metadata/476a82e3-c584-4a66-976b-8f10bdbf0d46/download","source":{"id":"https://openalex.org/S4306402259","display_name":"Archive ouverte UNIGE (University of Geneva)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114457229","host_organization_name":"University of Geneva","host_organization_lineage":["https://openalex.org/I114457229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2045-2322","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:01a151534228496e9a738c954869c8e2","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/01a151534228496e9a738c954869c8e2","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-021-86185-3","doi":"https://doi.org/10.1038/s41598-021-86185-3","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-021-86185-3","pdf_url":"https://www.nature.com/articles/s41598-021-86185-3.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8371999859809875,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3138765776.pdf","grobid_xml":"https://content.openalex.org/works/W3138765776.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1986825509","https://openalex.org/W2002231670","https://openalex.org/W2010090512","https://openalex.org/W2021800919","https://openalex.org/W2045507473","https://openalex.org/W2049573001","https://openalex.org/W2083717857","https://openalex.org/W2097470434","https://openalex.org/W2118105969","https://openalex.org/W2178700827","https://openalex.org/W2295658016","https://openalex.org/W2752217967","https://openalex.org/W2805284886","https://openalex.org/W2888059426","https://openalex.org/W2894732589","https://openalex.org/W2900472770","https://openalex.org/W3014164617","https://openalex.org/W3034308373","https://openalex.org/W4210991337"],"related_works":["https://openalex.org/W4220919892","https://openalex.org/W1986825509","https://openalex.org/W2894732589","https://openalex.org/W4401577579","https://openalex.org/W3193513325","https://openalex.org/W2066287940","https://openalex.org/W2045507473","https://openalex.org/W7145010258","https://openalex.org/W2064320238","https://openalex.org/W4411849265"],"abstract_inverted_index":{"Keratoconus":[0,83],"is":[1],"a":[2],"highly":[3],"prevalent":[4],"corneal":[5,10,52,92,106,113,135],"disorder":[6],"characterized":[7],"by":[8],"progressive":[9],"thinning,":[11],"steepening":[12],"and":[13,22,43,50,61,101,104],"irregular":[14],"astigmatism.":[15],"To":[16],"date,":[17],"pathophysiology":[18],"of":[19,38,121,133],"keratoconus":[20,42,62,76,139],"development":[21],"progression":[23],"remains":[24],"debated.":[25],"In":[26],"this":[27],"study,":[28],"we":[29],"retrospectively":[30],"analysed":[31],"topographic":[32],"elevation":[33],"maps":[34],"from":[35,58],"3227":[36,39],"eyes":[37,60,63,84],"patients":[40],"(969":[41],"2258":[44],"normal":[45,59],"eyes)":[46],"to":[47,74,79,87],"calculate":[48],"anterior":[49],"posterior":[51],"surface":[53,93,114,136],"area.":[54],"We":[55,123],"compared":[56],"results":[57,127],"using":[64],"the":[65,80,97,134],"Mann-Whitney":[66],"U":[67],"test.":[68],"The":[69],"Kruskal-Wallis":[70],"test":[71],"was":[72,116],"used":[73],"compare":[75],"stages":[77],"according":[78],"Amsler-Krumeich":[81],"classification.":[82],"were":[85],"shown":[86],"have":[88],"statistically":[89],"significantly":[90],"larger":[91],"areas,":[94],"measured":[95],"at":[96],"central":[98],"4.0":[99],"mm":[100],"8.0":[102],"mm,":[103],"total":[105],"diameter.":[107],"However,":[108],"no":[109],"significant":[110],"increase":[111],"in":[112],"area":[115,137],"seen":[117],"with":[118,138],"increasing":[119],"severity":[120],"keratoconus.":[122],"suggest":[124],"that":[125],"these":[126],"indicate":[128],"redistribution,":[129],"rather":[130],"than":[131],"increase,":[132],"severity.":[140]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-03-29T00:00:00"}