{"id":"https://openalex.org/W3138470259","doi":"https://doi.org/10.7554/elife.59798","title":"Development of visual motion integration involves coordination of multiple cortical stages","display_name":"Development of visual motion integration involves coordination of multiple cortical stages","publication_year":2021,"publication_date":"2021-03-22","ids":{"openalex":"https://openalex.org/W3138470259","doi":"https://doi.org/10.7554/elife.59798","mag":"3138470259","pmid":"https://pubmed.ncbi.nlm.nih.gov/33749595","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7984838"},"language":"en","primary_location":{"id":"doi:10.7554/elife.59798","doi":"https://doi.org/10.7554/elife.59798","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.59798","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.59798","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036789837","display_name":"Augusto Abel Lempel","orcid":"https://orcid.org/0000-0002-3644-2690","observed_orcids":["https://orcid.org/0000-0002-3644-2690"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Augusto A Lempel","raw_affiliation_strings":["Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States","Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, United States"],"raw_orcid":"https://orcid.org/0000-0002-3644-2690","affiliations":[{"raw_affiliation_string":"Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, United States","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033354962","display_name":"Kristina J. Nielsen","orcid":"https://orcid.org/0000-0002-9155-2972","observed_orcids":["https://orcid.org/0000-0002-9155-2972"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kristina J Nielsen","raw_affiliation_strings":["Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States","Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, United States"],"raw_orcid":"https://orcid.org/0000-0002-9155-2972","affiliations":[{"raw_affiliation_string":"Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Zanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, United States","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5033354962"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":0.5249,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.57400902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"10","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10427","display_name":"Visual perception and processing mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12032","display_name":"Multisensory perception and integration","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-visual-cortex","display_name":"primary visual cortex","score":0.781000018119812},{"id":"https://openalex.org/keywords/posterior-parietal-cortex","display_name":"posterior parietal cortex","score":0.6150000095367432},{"id":"https://openalex.org/keywords/cortical-development","display_name":"cortical development","score":0.5989999771118164},{"id":"https://openalex.org/keywords/hierarchical-processing","display_name":"hierarchical processing","score":0.8100000023841858},{"id":"https://openalex.org/keywords/direction-selectivity","display_name":"direction selectivity","score":0.8149999976158142},{"id":"https://openalex.org/keywords/global-motion-processing","display_name":"global motion processing","score":0.7260000109672546},{"id":"https://openalex.org/keywords/visual-cortex-maturation","display_name":"visual cortex maturation","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C2779345533","wikidata":"https://www.wikidata.org/wiki/Q75785","display_name":"Visual cortex","level":2,"score":0.7599630951881409},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6160045862197876},{"id":"https://openalex.org/C104114177","wikidata":"https://www.wikidata.org/wiki/Q79782","display_name":"Motion (physics)","level":2,"score":0.5921726226806641},{"id":"https://openalex.org/C48575856","wikidata":"https://www.wikidata.org/wiki/Q852504","display_name":"Motion perception","level":3,"score":0.5742091536521912},{"id":"https://openalex.org/C119088629","wikidata":"https://www.wikidata.org/wiki/Q558363","display_name":"Visual system","level":3,"score":0.5148791074752808},{"id":"https://openalex.org/C2778251979","wikidata":"https://www.wikidata.org/wiki/Q7936617","display_name":"Visual processing","level":3,"score":0.5135800838470459},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.48025253415107727},{"id":"https://openalex.org/C178253425","wikidata":"https://www.wikidata.org/wiki/Q162668","display_name":"Visual perception","level":3,"score":0.4709677994251251},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.44032400846481323},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3490528464317322},{"id":"https://openalex.org/C26760741","wikidata":"https://www.wikidata.org/wiki/Q160402","display_name":"Perception","level":2,"score":0.3482941687107086},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3433793783187866},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005289","descriptor_name":"Ferrets","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009039","descriptor_name":"Motion Perception","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010775","descriptor_name":"Photic Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014793","descriptor_name":"Visual Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014795","descriptor_name":"Visual Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.7554/elife.59798","doi":"https://doi.org/10.7554/elife.59798","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.59798","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7984838","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7984838","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"Text"},{"id":"pmid:33749595","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33749595","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:a5cd64cc7b924bd484c94335f6512237","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a5cd64cc7b924bd484c94335f6512237","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife, Vol 10 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.7554/elife.59798","doi":"https://doi.org/10.7554/elife.59798","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.59798","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2154508794","display_name":null,"funder_award_id":"EY027853","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G3537372498","display_name":"The impact of visual experience on the development of the motion pathway in the ferret","funder_award_id":"R01EY027853","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W209318144","https://openalex.org/W1480058201","https://openalex.org/W1539026306","https://openalex.org/W1610553731","https://openalex.org/W1967476298","https://openalex.org/W1972115727","https://openalex.org/W1976985517","https://openalex.org/W1989452459","https://openalex.org/W1997175896","https://openalex.org/W1998147476","https://openalex.org/W1998768495","https://openalex.org/W2004076022","https://openalex.org/W2014230143","https://openalex.org/W2017108196","https://openalex.org/W2027892181","https://openalex.org/W2063632045","https://openalex.org/W2067788014","https://openalex.org/W2069466380","https://openalex.org/W2077035528","https://openalex.org/W2081805772","https://openalex.org/W2081826483","https://openalex.org/W2097167689","https://openalex.org/W2105714994","https://openalex.org/W2116451226","https://openalex.org/W2118784177","https://openalex.org/W2120877950","https://openalex.org/W2129181505","https://openalex.org/W2130508503","https://openalex.org/W2145928782","https://openalex.org/W2159609503","https://openalex.org/W2162162475","https://openalex.org/W2206327616","https://openalex.org/W2444566579","https://openalex.org/W2761696233","https://openalex.org/W2884481634","https://openalex.org/W2908336270","https://openalex.org/W2980065358","https://openalex.org/W4294214781"],"related_works":["https://openalex.org/W4402904765","https://openalex.org/W2908336270","https://openalex.org/W7133221652","https://openalex.org/W4412460972","https://openalex.org/W2112591571","https://openalex.org/W1968676861","https://openalex.org/W2973684224","https://openalex.org/W1990837625","https://openalex.org/W2966386615","https://openalex.org/W2061869872"],"abstract_inverted_index":{"A":[0],"central":[1],"feature":[2],"of":[3,9,27,30,72],"cortical":[4,17],"function":[5],"is":[6,12,127],"hierarchical":[7],"processing":[8,18,48],"information.":[10],"Little":[11],"currently":[13],"known":[14],"about":[15],"how":[16,138],"cascades":[19],"develop.":[20],"Here,":[21],"we":[22],"investigate":[23],"the":[24,31,70,100,146],"joint":[25],"development":[26,71,115],"two":[28],"nodes":[29],"ferret's":[32],"visual":[33,37,124,139,148],"motion":[34,47,64,84,97],"pathway,":[35],"primary":[36],"cortex":[38],"(V1),":[39],"and":[40,74,141],"higher-level":[41],"area":[42],"PSS.":[43,110],"In":[44],"adult":[45],"animals,":[46],"transitions":[49],"from":[50,109],"local":[51],"to":[52,81],"global":[53,63],"computations":[54],"between":[55],"these":[56,103],"areas.":[57],"We":[58],"now":[59],"show":[60],"that":[61,114],"PSS":[62,75,96],"signals":[65],"emerge":[66],"a":[67,90],"week":[68],"after":[69],"V1":[73,79,104],"direction":[76],"selectivity.":[77],"Crucially,":[78],"responses":[80,105],"more":[82],"complex":[83],"stimuli":[85],"change":[86],"in":[87,89,120,122],"parallel,":[88],"manner":[91],"consistent":[92],"with":[93],"supporting":[94],"increased":[95],"integration.":[98],"At":[99],"same":[101],"time,":[102],"depend":[106],"on":[107],"feedback":[108],"Our":[111],"findings":[112],"suggest":[113],"does":[116],"not":[117],"just":[118],"proceed":[119],"parallel":[121],"different":[123],"areas,":[125],"it":[126],"coordinated":[128],"across":[129],"network":[130],"nodes.":[131],"This":[132],"has":[133],"important":[134],"implications":[135],"for":[136],"understanding":[137],"experience":[140],"developmental":[142],"disorders":[143],"can":[144],"influence":[145],"developing":[147],"system.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-03-29T00:00:00"}