{"id":"https://openalex.org/W3136981056","doi":"https://doi.org/10.3389/fmed.2021.661203","title":"Microbiome, Immunosenescence, and Chronic Kidney Disease","display_name":"Microbiome, Immunosenescence, and Chronic Kidney Disease","publication_year":2021,"publication_date":"2021-03-19","ids":{"openalex":"https://openalex.org/W3136981056","doi":"https://doi.org/10.3389/fmed.2021.661203","mag":"3136981056","pmid":"https://pubmed.ncbi.nlm.nih.gov/33816535","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8017168"},"language":"en","primary_location":{"id":"doi:10.3389/fmed.2021.661203","doi":"https://doi.org/10.3389/fmed.2021.661203","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2021.661203","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmed.2021.661203/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fmed.2021.661203/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047281963","display_name":"Elisavet Stavropoulou","orcid":"https://orcid.org/0000-0002-8299-9035","observed_orcids":["https://orcid.org/0000-0002-8299-9035"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I4210149159","display_name":"H\u00f4pital de Sion","ror":"https://ror.org/055awd420","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210149159"]},{"id":"https://openalex.org/I4210161110","display_name":"H\u00f4pital du Valais","ror":"https://ror.org/0579hyr20","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210161110"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Elisavet Stavropoulou","raw_affiliation_strings":["CHUV (Centre Hospitalier Universitaire Vaudois), Rue du Bugnon, Lausanne, Switzerland","Department of Infectious Diseases, Central Institute, Valais Hospital, Sion, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CHUV (Centre Hospitalier Universitaire Vaudois), Rue du Bugnon, Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]},{"raw_affiliation_string":"Department of Infectious Diseases, Central Institute, Valais Hospital, Sion, Switzerland","institution_ids":["https://openalex.org/I4210149159","https://openalex.org/I4210161110"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065637664","display_name":"Konstantia M. Kantartzi","orcid":"https://orcid.org/0000-0002-9366-7466","observed_orcids":["https://orcid.org/0000-0002-9366-7466"]},"institutions":[{"id":"https://openalex.org/I147962203","display_name":"Democritus University of Thrace","ror":"https://ror.org/03bfqnx40","country_code":"GR","type":"education","lineage":["https://openalex.org/I147962203"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Konstantia Kantartzi","raw_affiliation_strings":["Nephrology Clinic, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology Clinic, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece","institution_ids":["https://openalex.org/I147962203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035050571","display_name":"Christina Tsigalou","orcid":"https://orcid.org/0000-0002-7869-6824","observed_orcids":["https://orcid.org/0000-0002-7869-6824"]},"institutions":[{"id":"https://openalex.org/I147962203","display_name":"Democritus University of Thrace","ror":"https://ror.org/03bfqnx40","country_code":"GR","type":"education","lineage":["https://openalex.org/I147962203"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Christina Tsigalou","raw_affiliation_strings":["Laboratory of Microbiology, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Microbiology, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece","institution_ids":["https://openalex.org/I147962203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026100126","display_name":"Konstantina Aftzoglou","orcid":"https://orcid.org/0009-0001-8383-0258","observed_orcids":["https://orcid.org/0009-0001-8383-0258"]},"institutions":[{"id":"https://openalex.org/I74788687","display_name":"Comenius University Bratislava","ror":"https://ror.org/0587ef340","country_code":"SK","type":"education","lineage":["https://openalex.org/I74788687"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"Konstantina Aftzoglou","raw_affiliation_strings":["Medical School, Comenius University, Bratislava, Slovakia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical School, Comenius University, Bratislava, Slovakia","institution_ids":["https://openalex.org/I74788687"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chrysa Voidarou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chrysa Voidarou","raw_affiliation_strings":["Department of Public Health P.U., Arta, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health P.U., Arta, Greece","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071387705","display_name":"Theocharis G. Konstantinidis","orcid":"https://orcid.org/0000-0003-4296-3414","observed_orcids":["https://orcid.org/0000-0003-4296-3414"]},"institutions":[{"id":"https://openalex.org/I147962203","display_name":"Democritus University of Thrace","ror":"https://ror.org/03bfqnx40","country_code":"GR","type":"education","lineage":["https://openalex.org/I147962203"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Theocharis Konstantinidis","raw_affiliation_strings":["Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece","institution_ids":["https://openalex.org/I147962203"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001059217","display_name":"Mariana Carmen Chifiriuc","orcid":"https://orcid.org/0000-0001-6098-1857","observed_orcids":["https://orcid.org/0000-0001-6098-1857"]},"institutions":[{"id":"https://openalex.org/I141595442","display_name":"University of Bucharest","ror":"https://ror.org/02x2v6p15","country_code":"RO","type":"education","lineage":["https://openalex.org/I141595442"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Mariana Carmen Chifiriuc","raw_affiliation_strings":["Laboratory of Microbiology, Faculty of Biology, The Research Institute of the University of Bucharest (ICUB), University of Bucharest, Bucharest, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Microbiology, Faculty of Biology, The Research Institute of the University of Bucharest (ICUB), University of Bucharest, Bucharest, Romania","institution_ids":["https://openalex.org/I141595442"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088114673","display_name":"Elias D. Thodis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I147962203","display_name":"Democritus University of Thrace","ror":"https://ror.org/03bfqnx40","country_code":"GR","type":"education","lineage":["https://openalex.org/I147962203"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Elias Thodis","raw_affiliation_strings":["Nephrology Clinic, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology Clinic, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece","institution_ids":["https://openalex.org/I147962203"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075094506","display_name":"Eugenia Bezirtzoglou","orcid":"https://orcid.org/0000-0002-2010-2544","observed_orcids":["https://orcid.org/0000-0002-2010-2544","https://orcid.org/0000-0002-6347-265X"]},"institutions":[{"id":"https://openalex.org/I147962203","display_name":"Democritus University of Thrace","ror":"https://ror.org/03bfqnx40","country_code":"GR","type":"education","lineage":["https://openalex.org/I147962203"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Eugenia Bezirtzoglou","raw_affiliation_strings":["Laboratory of Hygiene and Environmental Protection, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Hygiene and Environmental Protection, Department of Medicine, Democritus University of Thrace, Alexandroupoli, Greece","institution_ids":["https://openalex.org/I147962203"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5047281963","https://openalex.org/A5065637664"],"corresponding_institution_ids":["https://openalex.org/I147962203","https://openalex.org/I2802229882","https://openalex.org/I4210149159","https://openalex.org/I4210161110"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":0.5507,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.47384538,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"8","issue":null,"first_page":"661203","last_page":"661203"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9940000176429749},{"id":"https://openalex.org/keywords/immunosenescence","display_name":"immunosenescence","score":0.9490000009536743},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":1.0},{"id":"https://openalex.org/keywords/gut-kidney-axis","display_name":"gut-kidney axis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/gut-dysbiosis","display_name":"gut dysbiosis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/inflammaging","display_name":"inflammaging","score":0.9110000133514404},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6710000038146973},{"id":"https://openalex.org/keywords/pathobionts","display_name":"pathobionts","score":0.8489999771118164},{"id":"https://openalex.org/keywords/sarcopenia","display_name":"sarcopenia","score":0.9399999976158142},{"id":"https://openalex.org/keywords/renal-disease-pathogenesis","display_name":"renal disease pathogenesis","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.8152902126312256},{"id":"https://openalex.org/C2779056147","wikidata":"https://www.wikidata.org/wiki/Q1660191","display_name":"Immunosenescence","level":3,"score":0.8059187531471252},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.7514695525169373},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.7414528727531433},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.6173612475395203},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5268025398254395},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5264647603034973},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5250083208084106},{"id":"https://openalex.org/C3019978661","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut microbiome","level":3,"score":0.4914933443069458},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.48939791321754456},{"id":"https://openalex.org/C2776214593","wikidata":"https://www.wikidata.org/wiki/Q1787939","display_name":"Sarcopenia","level":2,"score":0.4177483320236206},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4143359363079071},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.35527583956718445},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3125914931297302},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17369037866592407},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12914571166038513},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.06968450546264648}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/fmed.2021.661203","doi":"https://doi.org/10.3389/fmed.2021.661203","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2021.661203","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmed.2021.661203/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8017168","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8017168","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Med (Lausanne)","raw_type":"Text"},{"id":"pmid:33816535","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33816535","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in medicine","raw_type":"Journal Article"},{"id":"pmh:oai:serval.unil.ch:BIB_CEB61B5A05D1","doi":null,"is_oa":true,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_CEB61B5A05D1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in medicine, vol. 8, pp. 661203","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unil.ch:iris/216844","doi":null,"is_oa":true,"landing_page_url":"https://iris.unil.ch/handle/iris/216844","pdf_url":"https://iris.unil.ch/bitstreams/52ba2673-8ff3-45f4-b763-b421f7663a98/download","source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:doaj.org/article:72c564812eb140288d8199f75c2acfd4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/72c564812eb140288d8199f75c2acfd4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Medicine, Vol 8 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fmed.2021.661203","doi":"https://doi.org/10.3389/fmed.2021.661203","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2021.661203","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmed.2021.661203/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3136981056.pdf","grobid_xml":"https://content.openalex.org/works/W3136981056.grobid-xml"},"referenced_works_count":97,"referenced_works":["https://openalex.org/W4482768","https://openalex.org/W1491878153","https://openalex.org/W1529074450","https://openalex.org/W1540150301","https://openalex.org/W1579802326","https://openalex.org/W1584309458","https://openalex.org/W1767271760","https://openalex.org/W1863548789","https://openalex.org/W1898944617","https://openalex.org/W1916529790","https://openalex.org/W1948266836","https://openalex.org/W1985043041","https://openalex.org/W1989256150","https://openalex.org/W1989737633","https://openalex.org/W1994873752","https://openalex.org/W1998399313","https://openalex.org/W2001902542","https://openalex.org/W2002688213","https://openalex.org/W2005371431","https://openalex.org/W2012173754","https://openalex.org/W2012706589","https://openalex.org/W2015737228","https://openalex.org/W2018311782","https://openalex.org/W2020272944","https://openalex.org/W2020807889","https://openalex.org/W2039799375","https://openalex.org/W2048450564","https://openalex.org/W2055601570","https://openalex.org/W2058211193","https://openalex.org/W2064346298","https://openalex.org/W2069212958","https://openalex.org/W2072613939","https://openalex.org/W2072712640","https://openalex.org/W2073075095","https://openalex.org/W2073359524","https://openalex.org/W2075578688","https://openalex.org/W2076027168","https://openalex.org/W2076983697","https://openalex.org/W2083102356","https://openalex.org/W2087292184","https://openalex.org/W2091588484","https://openalex.org/W2091793708","https://openalex.org/W2098363800","https://openalex.org/W2101683974","https://openalex.org/W2102813808","https://openalex.org/W2104843066","https://openalex.org/W2104975759","https://openalex.org/W2108894325","https://openalex.org/W2113945548","https://openalex.org/W2122231459","https://openalex.org/W2124392720","https://openalex.org/W2125360614","https://openalex.org/W2128769815","https://openalex.org/W2131419587","https://openalex.org/W2134718821","https://openalex.org/W2141013052","https://openalex.org/W2141675485","https://openalex.org/W2155124532","https://openalex.org/W2163851387","https://openalex.org/W2168195605","https://openalex.org/W2207819727","https://openalex.org/W2303714942","https://openalex.org/W2401857311","https://openalex.org/W2404233557","https://openalex.org/W2417692274","https://openalex.org/W2487377689","https://openalex.org/W2529139403","https://openalex.org/W2549009399","https://openalex.org/W2550084345","https://openalex.org/W2550965594","https://openalex.org/W2552808209","https://openalex.org/W2561487455","https://openalex.org/W2592974986","https://openalex.org/W2601732801","https://openalex.org/W2604156122","https://openalex.org/W2756308812","https://openalex.org/W2773739769","https://openalex.org/W2782187941","https://openalex.org/W2793215678","https://openalex.org/W2884081989","https://openalex.org/W2888916586","https://openalex.org/W2889098175","https://openalex.org/W2906983625","https://openalex.org/W2937015825","https://openalex.org/W2944041341","https://openalex.org/W2981568805","https://openalex.org/W3005957464","https://openalex.org/W3012426108","https://openalex.org/W3033189901","https://openalex.org/W3034168062","https://openalex.org/W3036822194","https://openalex.org/W3037038749","https://openalex.org/W3124371013","https://openalex.org/W3140694349","https://openalex.org/W3163564325","https://openalex.org/W4299527519","https://openalex.org/W4300563131"],"related_works":["https://openalex.org/W4415959889","https://openalex.org/W4361212403","https://openalex.org/W4414845012","https://openalex.org/W7151379699","https://openalex.org/W4385383157","https://openalex.org/W2886676793","https://openalex.org/W3124371013","https://openalex.org/W2973093541","https://openalex.org/W4389070529","https://openalex.org/W7221758713"],"abstract_inverted_index":{"The":[0,34],"gut":[1,27,134],"microbiome":[2,66,105],"is":[3,49,73,118],"known":[4],"as":[5,87],"an":[6,79],"important":[7],"predictive":[8],"tool":[9],"for":[10],"perceiving":[11],"characteristic":[12],"shifts":[13,53],"in":[14,54,99,106],"disease":[15],"states.":[16],"Multiple":[17,84],"renal":[18],"diseases":[19],"and":[20,58,70,94,108,117,126,136],"pathologies":[21],"seem":[22],"to":[23,67,120,123],"be":[24],"associated":[25],"with":[26,78],"dysbiosis":[28],"which":[29],"directly":[30],"affects":[31],"host":[32],"homeostasis.":[33],"gastrointestinal-kidney":[35],"dialogue":[36],"confers":[37],"interesting":[38],"information":[39],"about":[40],"the":[41,55,65,88,101,104,129,133],"pathogenesis":[42],"of":[43,61,81,103,132],"multiple":[44],"kidney":[45,137],"diseases.":[46],"Moreover,":[47],"aging":[48],"followed":[50],"by":[51,75],"specific":[52],"human":[56],"microbiome,":[57],"gradual":[59],"elimination":[60],"physiological":[62],"functions":[63],"predisposes":[64],"inflammaging,":[68],"sarcopenia,":[69],"disease.":[71,109],"Aging":[72],"characterized":[74],"a":[76],"microbiota":[77,135],"abundance":[80],"disease-associated":[82],"pathobionts.":[83],"factors":[85],"such":[86],"immune":[89],"system,":[90],"environment,":[91],"medication,":[92],"diet,":[93],"genetic":[95],"endowment":[96],"are":[97],"involved":[98,130],"determining":[100],"age":[102],"health":[107],"Our":[110],"present":[111],"review":[112],"promotes":[113],"recently":[114],"acquired":[115],"knowledge":[116],"expected":[119],"inspire":[121],"researchers":[122],"advance":[124],"studies":[125],"investigations":[127],"on":[128],"pathways":[131],"axis.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2021-03-29T00:00:00"}
