{"id":"https://openalex.org/W3136947911","doi":"https://doi.org/10.7554/elife.64327","title":"Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task","display_name":"Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task","publication_year":2021,"publication_date":"2021-03-15","ids":{"openalex":"https://openalex.org/W3136947911","doi":"https://doi.org/10.7554/elife.64327","mag":"3136947911","pmid":"https://pubmed.ncbi.nlm.nih.gov/33721552","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7963470"},"language":"en","primary_location":{"id":"doi:10.7554/elife.64327","doi":"https://doi.org/10.7554/elife.64327","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.64327","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.64327","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024682637","display_name":"Hongdian Yang","orcid":"https://orcid.org/0000-0002-5203-9519","observed_orcids":["https://orcid.org/0000-0002-5203-9519"]},"institutions":[{"id":"https://openalex.org/I103635307","display_name":"University of California, Riverside","ror":"https://ror.org/03nawhv43","country_code":"US","type":"education","lineage":["https://openalex.org/I103635307"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hongdian Yang","raw_affiliation_strings":["Department of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA","Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA","institution_ids":["https://openalex.org/I103635307"]},{"raw_affiliation_string":"Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, United States","institution_ids":["https://openalex.org/I103635307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021371430","display_name":"Bilal A. Bari","orcid":"https://orcid.org/0000-0002-8381-3802","observed_orcids":["https://orcid.org/0000-0002-8381-3802"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bilal A. Bari","raw_affiliation_strings":["Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA","Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, United States","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005224008","display_name":"Jeremiah Y. Cohen","orcid":"https://orcid.org/0000-0002-4768-7124","observed_orcids":["https://orcid.org/0000-0002-4768-7124"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremiah Y. Cohen","raw_affiliation_strings":["Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA","Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, United States","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061719214","display_name":"Daniel H. O\u2019Connor","orcid":"https://orcid.org/0000-0002-9193-6714","observed_orcids":["https://orcid.org/0000-0002-9193-6714"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Daniel H. O\u2019Connor","raw_affiliation_strings":["Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA","Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, United States"],"raw_orcid":"https://orcid.org/0000-0002-9193-6714","affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, MD, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Department of Neuroscience, Brain Science Institute, and Kavli Neuroscience Discovery Institute, Johns Hopkins School of Medicine, Baltimore, United States","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5024682637","https://openalex.org/A5061719214"],"corresponding_institution_ids":["https://openalex.org/I103635307","https://openalex.org/I145311948","https://openalex.org/I2799853436"],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":3.9364,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.94612521,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"10","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.8202999830245972,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.8202999830245972,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.059700001031160355,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.02930000051856041,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/locus-coeruleus","display_name":"locus coeruleus","score":1.0},{"id":"https://openalex.org/keywords/primary-somatosensory-cortex","display_name":"primary somatosensory cortex","score":0.9890000224113464},{"id":"https://openalex.org/keywords/pupil-size","display_name":"pupil size","score":0.9779999852180481},{"id":"https://openalex.org/keywords/tactile-detection","display_name":"tactile detection","score":0.699999988079071},{"id":"https://openalex.org/keywords/neuronal-spiking","display_name":"neuronal spiking","score":0.6420000195503235},{"id":"https://openalex.org/keywords/membrane-depolarization","display_name":"membrane depolarization","score":0.8820000290870667},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C2778468602","wikidata":"https://www.wikidata.org/wiki/Q1470452","display_name":"Locus coeruleus","level":3,"score":0.9116479158401489},{"id":"https://openalex.org/C2777394604","wikidata":"https://www.wikidata.org/wiki/Q173318","display_name":"Pupil","level":2,"score":0.8645471334457397},{"id":"https://openalex.org/C172497186","wikidata":"https://www.wikidata.org/wiki/Q328835","display_name":"Somatosensory system","level":2,"score":0.780708372592926},{"id":"https://openalex.org/C149288182","wikidata":"https://www.wikidata.org/wiki/Q7260673","display_name":"Pupillary response","level":3,"score":0.7304759621620178},{"id":"https://openalex.org/C2987277156","wikidata":"https://www.wikidata.org/wiki/Q173318","display_name":"Pupil diameter","level":3,"score":0.6835287809371948},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6406044363975525},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4743976593017578},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.43528324365615845},{"id":"https://openalex.org/C4141045","wikidata":"https://www.wikidata.org/wiki/Q83183","display_name":"Depolarization","level":2,"score":0.42441830039024353},{"id":"https://openalex.org/C2984127161","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neural activity","level":2,"score":0.4165136218070984},{"id":"https://openalex.org/C2779345533","wikidata":"https://www.wikidata.org/wiki/Q75785","display_name":"Visual cortex","level":2,"score":0.4116341471672058},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.361464262008667},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32861024141311646},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2954583764076233},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22052648663520813},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.1557312309741974},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.1376410722732544}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004106","descriptor_name":"Dilatation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004558","descriptor_name":"Electric Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008125","descriptor_name":"Locus Coeruleus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011680","descriptor_name":"Pupil","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D012201","descriptor_name":"Reward","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013003","descriptor_name":"Somatosensory Cortex","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055698","descriptor_name":"Touch Perception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.7554/elife.64327","doi":"https://doi.org/10.7554/elife.64327","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.64327","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},{"id":"doi:10.1101/2020.06.04.134676","doi":"https://doi.org/10.1101/2020.06.04.134676","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2020.06.04.134676","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2020/10/27/2020.06.04.134676.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:7963470","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7963470","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"Text"},{"id":"pmid:33721552","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33721552","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:f032669c3f2f4afeb8f255cb412d5cdf","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f032669c3f2f4afeb8f255cb412d5cdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife, Vol 10 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.7554/elife.64327","doi":"https://doi.org/10.7554/elife.64327","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.64327","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"eLife","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1877490212","display_name":"The role of norepinephrine in enabling behavioral change during uncertainty","funder_award_id":"F30MH110084","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G2142176442","display_name":"Medical Scientist Training Program","funder_award_id":"T32GM007309","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4593718068","display_name":"Circuit and cellular dynamics in mouse cortex during tactile detection","funder_award_id":"R01NS089652","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G4609780072","display_name":"JHU Center for Neuroscience Research","funder_award_id":"P30NS050274","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G794918378","display_name":"Locus Coeruleus-Norepinephrine Modulation of Sensory Response and Tactile Perception","funder_award_id":"R01NS107355","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8155357","display_name":"Norepinephrine modulation of neocortex during flexible behavior","funder_award_id":"R01NS104834","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000901299","display_name":"Top-down mechanisms and modulation of flexible tactile discrimination","funder_award_id":"R01NS112200","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G9000903403","display_name":"Medical Scientist Training Program","funder_award_id":"T32GM136577","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W137814523","https://openalex.org/W1519578210","https://openalex.org/W1785119030","https://openalex.org/W1969772883","https://openalex.org/W1984202832","https://openalex.org/W2008232229","https://openalex.org/W2011868904","https://openalex.org/W2020696485","https://openalex.org/W2021271087","https://openalex.org/W2022561563","https://openalex.org/W2036592327","https://openalex.org/W2047390168","https://openalex.org/W2047964244","https://openalex.org/W2049894354","https://openalex.org/W2057594895","https://openalex.org/W2080275784","https://openalex.org/W2086338669","https://openalex.org/W2113827256","https://openalex.org/W2115095583","https://openalex.org/W2116679324","https://openalex.org/W2129928127","https://openalex.org/W2137259486","https://openalex.org/W2144214580","https://openalex.org/W2210396547","https://openalex.org/W2211009999","https://openalex.org/W2262696703","https://openalex.org/W2411440652","https://openalex.org/W2412646938","https://openalex.org/W2481900801","https://openalex.org/W2528714087","https://openalex.org/W2551360963","https://openalex.org/W2558181418","https://openalex.org/W2758014172","https://openalex.org/W2830611829","https://openalex.org/W2877442110","https://openalex.org/W2897744504","https://openalex.org/W2905222095","https://openalex.org/W2953649774","https://openalex.org/W3013357458","https://openalex.org/W3028295088","https://openalex.org/W3035555092","https://openalex.org/W3091711460","https://openalex.org/W3105079918"],"related_works":["https://openalex.org/W4210618141","https://openalex.org/W2210396547","https://openalex.org/W2232373047","https://openalex.org/W6911137037","https://openalex.org/W1601100579","https://openalex.org/W3035916092","https://openalex.org/W7215700585","https://openalex.org/W4295757400","https://openalex.org/W3159049463","https://openalex.org/W7071679108"],"abstract_inverted_index":{"We":[0],"examined":[1],"the":[2,7,13,40,50],"relationships":[3,51],"between":[4,42,52],"activity":[5,11],"in":[6,12,21],"locus":[8],"coeruleus":[9],"(LC),":[10],"primary":[14],"somatosensory":[15],"cortex":[16],"(S1),":[17],"and":[18,37,44,55,78],"pupil":[19,38,45,56,70],"diameter":[20,71],"mice":[22],"performing":[23],"a":[24,83],"tactile":[25],"detection":[26],"task.":[27],"While":[28],"LC":[29,76,87],"spiking":[30,77],"consistently":[31],"preceded":[32],"S1":[33,43],"membrane":[34],"potential":[35],"depolarization":[36],"dilation,":[39],"correlation":[41],"was":[46],"more":[47],"heterogeneous.":[48],"Furthermore,":[49],"LC,":[53],"S1,":[54],"varied":[57],"on":[58],"timescales":[59],"of":[60,86],"sub-seconds":[61],"to":[62],"seconds":[63],"within":[64],"trials.":[65],"Our":[66],"data":[67],"suggest":[68],"that":[69],"can":[72],"be":[73,80],"dissociated":[74],"from":[75],"cannot":[79],"used":[81],"as":[82],"stationary":[84],"index":[85],"activity.":[88]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-03-29T00:00:00"}