{"id":"https://openalex.org/W3136843333","doi":"https://doi.org/10.1111/rda.13925","title":"Promoter\u2010specific expression of the imprinted IGF2 gene in bovine oocytes and pre\u2010implantation embryos","display_name":"Promoter\u2010specific expression of the imprinted IGF2 gene in bovine oocytes and pre\u2010implantation embryos","publication_year":2021,"publication_date":"2021-03-13","ids":{"openalex":"https://openalex.org/W3136843333","doi":"https://doi.org/10.1111/rda.13925","mag":"3136843333","pmid":"https://pubmed.ncbi.nlm.nih.gov/33713470"},"language":"en","primary_location":{"id":"doi:10.1111/rda.13925","doi":"https://doi.org/10.1111/rda.13925","is_oa":false,"landing_page_url":"https://doi.org/10.1111/rda.13925","pdf_url":null,"source":{"id":"https://openalex.org/S147868187","display_name":"Reproduction in Domestic Animals","issn_l":"0044-5371","issn":["0044-5371","0936-6768","1439-0531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction in Domestic Animals","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W3136843333"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10183/247716","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022083735","display_name":"Bruna Rodrigues Willhelm","orcid":"https://orcid.org/0000-0002-4521-2475","observed_orcids":["https://orcid.org/0000-0002-4521-2475"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bruna Rodrigues Willhelm","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-4521-2475","affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004359385","display_name":"Elvis Ticiani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Elvis Ticiani","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050586967","display_name":"Karine Campagnolo","orcid":"https://orcid.org/0000-0001-6984-5907","observed_orcids":["https://orcid.org/0000-0001-6984-5907"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Karine Campagnolo","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-6984-5907","affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037342456","display_name":"Gabriella Borba de Oliveira","orcid":"https://orcid.org/0000-0002-1051-9653","observed_orcids":["https://orcid.org/0000-0002-1051-9653"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gabriella Borba de Oliveira","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-1051-9653","affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068471576","display_name":"Karine de Mattos","orcid":"https://orcid.org/0000-0001-8386-3028","observed_orcids":["https://orcid.org/0000-0001-8386-3028"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Karine de Mattos","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066905842","display_name":"Camilo Andr\u00e9s Pe\u00f1a Bello","orcid":"https://orcid.org/0000-0001-9053-7765","observed_orcids":["https://orcid.org/0000-0001-9053-7765"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Camilo Andr\u00e9s Pe\u00f1a Bello","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":"https://orcid.org/0000-0001-9053-7765","affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090927250","display_name":"Felipe Ledur Ongaratto","orcid":"https://orcid.org/0000-0002-3052-8768","observed_orcids":["https://orcid.org/0000-0002-3052-8768"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Felipe Ledur Ongaratto","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003085326","display_name":"P. Rodr\u00edguez-Villamil","orcid":"https://orcid.org/0009-0004-6982-7791","observed_orcids":["https://orcid.org/0009-0004-6982-7791"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Paula Rodriguez\u2010Villamil","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053602549","display_name":"Luciana Relly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45643870","display_name":"Pontif\u00edcia Universidade Cat\u00f3lica do Rio Grande do Sul","ror":"https://ror.org/025vmq686","country_code":"BR","type":"education","lineage":["https://openalex.org/I45643870"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luciana Relly","raw_affiliation_strings":["PUCRS, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PUCRS, Brazil","institution_ids":["https://openalex.org/I45643870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039397776","display_name":"Juliana Paula Martins Alves","orcid":"https://orcid.org/0000-0003-4536-0037","observed_orcids":["https://orcid.org/0000-0003-4536-0037"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Juliana Paula Martins Alves","raw_affiliation_strings":["Ceara State University (UECE), Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ceara State University (UECE), Fortaleza, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073290264","display_name":"Davide Rondina","orcid":"https://orcid.org/0000-0003-0474-8895","observed_orcids":["https://orcid.org/0000-0003-0474-8895"]},"institutions":[{"id":"https://openalex.org/I102939073","display_name":"Universidade Estadual do Cear\u00e1","ror":"https://ror.org/00sec1m50","country_code":"BR","type":"education","lineage":["https://openalex.org/I102939073"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Davide Rondina","raw_affiliation_strings":["Ceara State University (UECE), Fortaleza, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-0474-8895","affiliations":[{"raw_affiliation_string":"Ceara State University (UECE), Fortaleza, Brazil","institution_ids":["https://openalex.org/I102939073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068416026","display_name":"Jos\u00e9 Luiz Rodrigues","orcid":"https://orcid.org/0000-0003-3323-472X","observed_orcids":["https://orcid.org/0000-0003-3323-472X"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Luiz Rigo Rodrigues","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":"https://orcid.org/0000-0003-3323-472X","affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084357560","display_name":"Marcelo Bertolini","orcid":"https://orcid.org/0000-0003-0340-6148","observed_orcids":["https://orcid.org/0000-0003-0340-6148"]},"institutions":[{"id":"https://openalex.org/I130442723","display_name":"Universidade Federal do Rio Grande do Sul","ror":"https://ror.org/041yk2d64","country_code":"BR","type":"education","lineage":["https://openalex.org/I130442723"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Marcelo Bertolini","raw_affiliation_strings":["School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Veterinary Medicine, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil","institution_ids":["https://openalex.org/I130442723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5084357560"],"corresponding_institution_ids":["https://openalex.org/I130442723"],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.12,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.34696982,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"56","issue":"6","first_page":"857","last_page":"863"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11928","display_name":"Genetic Syndromes and Imprinting","score":0.7490000128746033,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11928","display_name":"Genetic Syndromes and Imprinting","score":0.7490000128746033,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.08720000088214874,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.08070000261068344,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/igf-ii","display_name":"insulin-like growth factor II","score":0.9470000267028809},{"id":"https://openalex.org/keywords/imprinted-genes","display_name":"imprinted genes","score":0.6819999814033508},{"id":"https://openalex.org/keywords/bovine-oocytes","display_name":"bovine oocytes","score":0.9279999732971191},{"id":"https://openalex.org/keywords/preimplantation-embryo","display_name":"preimplantation embryo","score":0.9259999990463257},{"id":"https://openalex.org/keywords/in-vitro-embryo-production","display_name":"in vitro embryo production","score":0.7710000276565552},{"id":"https://openalex.org/keywords/oocyte-maturation","display_name":"oocyte maturation","score":0.9470000267028809},{"id":"https://openalex.org/keywords/splice-variants","display_name":"splice variants","score":0.6029999852180481},{"id":"https://openalex.org/keywords/genomic-imprinting","display_name":"genomic imprinting","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C201492766","wikidata":"https://www.wikidata.org/wiki/Q84087","display_name":"Genomic imprinting","level":5,"score":0.7213408350944519},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.656904399394989},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.5480523109436035},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5322625041007996},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4787009060382843},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4506889581680298},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.354402095079422},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.34405940771102905},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.27638912200927734},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10437217354774475},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.057902008295059204}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005307","descriptor_name":"Fertilization in Vitro","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D007335","descriptor_name":"Insulin-Like Growth Factor II","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007335","descriptor_name":"Insulin-Like Growth Factor II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/rda.13925","doi":"https://doi.org/10.1111/rda.13925","is_oa":false,"landing_page_url":"https://doi.org/10.1111/rda.13925","pdf_url":null,"source":{"id":"https://openalex.org/S147868187","display_name":"Reproduction in Domestic Animals","issn_l":"0044-5371","issn":["0044-5371","0936-6768","1439-0531"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction in Domestic Animals","raw_type":"journal-article"},{"id":"pmid:33713470","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33713470","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Reproduction in domestic animals = Zuchthygiene","raw_type":"Journal Article"},{"id":"pmh:oai:www.lume.ufrgs.br:10183/247716","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/247716","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UFRGS","raw_type":"info:eu-repo/semantics/masterThesis"}],"best_oa_location":{"id":"pmh:oai:www.lume.ufrgs.br:10183/247716","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10183/247716","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UFRGS","raw_type":"info:eu-repo/semantics/masterThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1357125404","display_name":null,"funder_award_id":"449.509/2014\u20101","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"},{"id":"https://openalex.org/G2097844978","display_name":null,"funder_award_id":"407.280/2013-8","funder_id":"https://openalex.org/F4320322025","funder_display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico"}],"funders":[{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1496670813","https://openalex.org/W1533935872","https://openalex.org/W1977365399","https://openalex.org/W1988600076","https://openalex.org/W2022924863","https://openalex.org/W2036202473","https://openalex.org/W2042912474","https://openalex.org/W2056397474","https://openalex.org/W2057287546","https://openalex.org/W2067117349","https://openalex.org/W2072526865","https://openalex.org/W2073837875","https://openalex.org/W2082167522","https://openalex.org/W2083360679","https://openalex.org/W2093666076","https://openalex.org/W2094074349","https://openalex.org/W2119453558","https://openalex.org/W2122889283","https://openalex.org/W2127689095","https://openalex.org/W2155091020","https://openalex.org/W2158723358","https://openalex.org/W2179602430","https://openalex.org/W2852824123","https://openalex.org/W2892444606","https://openalex.org/W2910739516","https://openalex.org/W2955231306","https://openalex.org/W3006388413"],"related_works":["https://openalex.org/W1608832224","https://openalex.org/W1977365399","https://openalex.org/W2127689095","https://openalex.org/W2065242378","https://openalex.org/W2914982158","https://openalex.org/W1965245305","https://openalex.org/W2602128641","https://openalex.org/W2057659787","https://openalex.org/W2387468284","https://openalex.org/W2038244601"],"abstract_inverted_index":{"The":[0],"bovine":[1,41,209],"IGF2":[2,42,110,210],"locus":[3],"is":[4],"a":[5],"genomic":[6],"region":[7],"with":[8,123],"alternative":[9],"transcripts":[10,114,133,162],"controlled":[11],"by":[12,54,116],"five":[13,91],"promoters":[14,117],"(P0,":[15],"P1,":[16],"P2,":[17,119],"P3":[18,120,170,193],"and":[19,30,32,48,60,63,72,74,81,102,121,131,145,159,183,215,231],"P4).":[20],"As":[21],"transcriptional":[22],"regulation":[23],"can":[24],"affect":[25],"messenger":[26],"RNA":[27,99],"(mRNA)":[28],"stability":[29],"translation,":[31],"thus,":[33],"subsequent":[34],"biological":[35],"effects,":[36],"this":[37],"study":[38],"evaluated":[39],"the":[40,67,205,220],"promoter-specific":[43,111],"expression":[44,211],"patterns":[45],"in":[46,52,87,95,199,226,232,234],"oocytes":[47,144],"pre-implantation":[49,64],"embryos":[50,65],"produced":[51],"vitro":[53],"our":[55],"standard":[56],"IVP":[57,225],"procedures.":[58],"Immature":[59],"matured":[61,142],"oocytes,":[62],"at":[66,75,157,175],"1-,":[68],"2-,":[69],"4-,":[70],"8-":[71],"16-cell,":[73],"early":[76,190],"morula,":[77,79],"compact":[78],"blastocyst":[80,83],"expanded":[82],"stages":[84],"were":[85,163],"collected":[86],"three":[88],"pools":[89],"of":[90,109,129,228],"structures":[92],"per":[93],"stage,":[94],"four":[96,107],"replicates.":[97],"Total":[98],"was":[100,172],"extracted":[101],"subjected":[103],"to":[104,203,223],"RT-qPCR,":[105],"using":[106],"sets":[108],"primers":[112],"covering":[113],"driven":[115],"P0/P1,":[118],"P4,":[122],"fragments":[124],"sequenced":[125],"for":[126,208],"confirmation.":[127],"Expression":[128],"P2-":[130],"P4-derived":[132],"showed":[134],"an":[135],"initial":[136],"peak":[137],"between":[138],"immature":[139],"(P4)":[140],"or":[141],"(P2/P4)":[143],"2-cell":[146],"embryos,":[147],"gradually":[148],"falling":[149],"until":[150],"embryo":[151,216,229],"genome":[152],"activation":[153],"(EGA),":[154],"rising":[155],"again":[156],"compaction":[158],"cavitation.":[160],"P0/P1-derived":[161],"identified":[164],"after":[165],"EGA,":[166],"during":[167,189,212],"compaction,":[168],"whereas":[169,192],"activity":[171],"not":[173],"detected":[174],"any":[176],"stage.":[177],"Our":[178],"findings":[179],"suggest":[180],"that":[181],"P0/P1":[182],"P2":[184],"likely":[185],"have":[186],"secondary":[187],"roles":[188],"stages,":[191],"may":[194],"be":[195,204],"more":[196],"relevant":[197],"later":[198],"development.":[200],"P4":[201],"seems":[202],"main":[206,221],"pathway":[207],"oocyte":[213],"maturation":[214],"development":[217],"and,":[218],"therefore,":[219],"target":[222],"influence":[224],"modulation":[227],"growth":[230],"studies":[233],"developmental":[235],"biology.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-03-29T00:00:00"}