{"id":"https://openalex.org/W3136628740","doi":"https://doi.org/10.1128/mcb.00631-20","title":"Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7","display_name":"Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7","publication_year":2021,"publication_date":"2021-03-24","ids":{"openalex":"https://openalex.org/W3136628740","doi":"https://doi.org/10.1128/mcb.00631-20","mag":"3136628740","pmid":"https://pubmed.ncbi.nlm.nih.gov/33782039","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8316008"},"language":"en","primary_location":{"id":"doi:10.1128/mcb.00631-20","doi":"https://doi.org/10.1128/mcb.00631-20","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mcb.00631-20","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1128/MCB.00631-20?needAccess=true&role=button","source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.tandfonline.com/doi/pdf/10.1128/MCB.00631-20?needAccess=true&role=button","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101511103","display_name":"Xia Zhao","orcid":"https://orcid.org/0000-0001-7809-6098","observed_orcids":["https://orcid.org/0000-0001-7809-6098"]},"institutions":[{"id":"https://openalex.org/I4210143187","display_name":"First Affiliated Hospital of University of South China","ror":"https://ror.org/049z3cb60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143187"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xia Zhao","raw_affiliation_strings":["Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","institution_ids":["https://openalex.org/I4210143187"]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China","institution_ids":["https://openalex.org/I4210143187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100554633","display_name":"Weilei Dong","orcid":"https://orcid.org/0009-0000-5063-0308","observed_orcids":["https://orcid.org/0009-0000-5063-0308"]},"institutions":[{"id":"https://openalex.org/I4210143187","display_name":"First Affiliated Hospital of University of South China","ror":"https://ror.org/049z3cb60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143187"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weilei Dong","raw_affiliation_strings":["Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","institution_ids":["https://openalex.org/I4210143187"]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China","institution_ids":["https://openalex.org/I4210143187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017262283","display_name":"Guifang Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143187","display_name":"First Affiliated Hospital of University of South China","ror":"https://ror.org/049z3cb60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143187"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guifang Luo","raw_affiliation_strings":["Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","institution_ids":["https://openalex.org/I4210143187"]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China","institution_ids":["https://openalex.org/I4210143187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101791578","display_name":"Jing Xie","orcid":"https://orcid.org/0000-0003-3278-2812","observed_orcids":["https://orcid.org/0000-0003-3278-2812"]},"institutions":[{"id":"https://openalex.org/I4210143187","display_name":"First Affiliated Hospital of University of South China","ror":"https://ror.org/049z3cb60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143187"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Xie","raw_affiliation_strings":["Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","institution_ids":["https://openalex.org/I4210143187"]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China","institution_ids":["https://openalex.org/I4210143187"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454130","display_name":"Jie Liu","orcid":"https://orcid.org/0000-0002-6359-637X","observed_orcids":["https://orcid.org/0000-0002-6359-637X"]},"institutions":[{"id":"https://openalex.org/I4210143187","display_name":"First Affiliated Hospital of University of South China","ror":"https://ror.org/049z3cb60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143187"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Liu","raw_affiliation_strings":["Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","institution_ids":["https://openalex.org/I4210143187"]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China","institution_ids":["https://openalex.org/I4210143187"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085223654","display_name":"Furong Yu","orcid":"https://orcid.org/0000-0003-0801-3511","observed_orcids":["https://orcid.org/0000-0003-0801-3511"]},"institutions":[{"id":"https://openalex.org/I4210143187","display_name":"First Affiliated Hospital of University of South China","ror":"https://ror.org/049z3cb60","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210143187"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Furong Yu","raw_affiliation_strings":["Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China"],"raw_orcid":"https://orcid.org/0000-0003-0801-3511","affiliations":[{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China","institution_ids":["https://openalex.org/I4210143187"]},{"raw_affiliation_string":"Department of Gynaecology and Obstetrics, The First Affiliated Hospital of University of South China, Hengyang City, Hunan Province, China","institution_ids":["https://openalex.org/I4210143187"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085223654"],"corresponding_institution_ids":["https://openalex.org/I4210143187"],"apc_list":null,"apc_paid":null,"fwci":2.0321,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.88802086,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"41","issue":"6","first_page":"e0063120","last_page":"e0063120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circular-rna","display_name":"circular RNA","score":0.8399999737739563},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"cervical cancer","score":0.9559999704360962},{"id":"https://openalex.org/keywords/radioresistance-biology","display_name":"radioresistance (biology)","score":0.7409999966621399},{"id":"https://openalex.org/keywords/radiosensitivity","display_name":"radiosensitivity","score":0.9629999995231628},{"id":"https://openalex.org/keywords/hoxb7","display_name":"HOXB7","score":0.871999979019165},{"id":"https://openalex.org/keywords/mirna-sponge","display_name":"microRNA sponge","score":0.8209999799728394},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.7080000042915344},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8539999723434448},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7590000033378601},{"id":"https://openalex.org/keywords/cell-migration-and-invasion","display_name":"cell migration and invasion","score":0.9020000100135803},{"id":"https://openalex.org/keywords/tumor-growth","display_name":"tumor growth","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8093180656433105},{"id":"https://openalex.org/C58962609","wikidata":"https://www.wikidata.org/wiki/Q2353022","display_name":"Radioresistance","level":3,"score":0.7957597970962524},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.5811291933059692},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.5784688591957092},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5665755271911621},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5650734901428223},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4872209131717682},{"id":"https://openalex.org/C206684579","wikidata":"https://www.wikidata.org/wiki/Q4387689","display_name":"Radiosensitivity","level":3,"score":0.4829244315624237},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.40826156735420227},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3144928216934204},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.30459064245224},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09942996501922607},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.07463642954826355},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.056062668561935425},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05164313316345215},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.048673033714294434},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000079962","descriptor_name":"RNA, Circular","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015536","descriptor_name":"Down-Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D018398","descriptor_name":"Homeodomain Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020868","descriptor_name":"Gene Silencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/mcb.00631-20","doi":"https://doi.org/10.1128/mcb.00631-20","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mcb.00631-20","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1128/MCB.00631-20?needAccess=true&role=button","source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},{"id":"pmid:33782039","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33782039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8316008","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8316008/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Cell Biol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1128/mcb.00631-20","doi":"https://doi.org/10.1128/mcb.00631-20","is_oa":true,"landing_page_url":"https://doi.org/10.1128/mcb.00631-20","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1128/MCB.00631-20?needAccess=true&role=button","source":{"id":"https://openalex.org/S81455967","display_name":"Molecular and Cellular Biology","issn_l":"0270-7306","issn":["0270-7306","1067-8824","1098-5549"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3136628740.pdf","grobid_xml":"https://content.openalex.org/works/W3136628740.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1974412224","https://openalex.org/W1997751561","https://openalex.org/W2067807828","https://openalex.org/W2096464885","https://openalex.org/W2129904088","https://openalex.org/W2164230635","https://openalex.org/W2416910583","https://openalex.org/W2421850573","https://openalex.org/W2514837319","https://openalex.org/W2740221126","https://openalex.org/W2764294957","https://openalex.org/W2789990478","https://openalex.org/W2791843201","https://openalex.org/W2792763876","https://openalex.org/W2808576887","https://openalex.org/W2889646458","https://openalex.org/W2900955337","https://openalex.org/W2906131344","https://openalex.org/W2910599425","https://openalex.org/W2915506721","https://openalex.org/W2915572786","https://openalex.org/W2928737010","https://openalex.org/W2928902335","https://openalex.org/W2943966438","https://openalex.org/W2946282523","https://openalex.org/W2949710830","https://openalex.org/W2955511511","https://openalex.org/W2967043226","https://openalex.org/W2969228284","https://openalex.org/W2975340465","https://openalex.org/W3008977595","https://openalex.org/W3010206004","https://openalex.org/W3012503101","https://openalex.org/W3025942647","https://openalex.org/W3026378976"],"related_works":["https://openalex.org/W3121301221","https://openalex.org/W4307429745","https://openalex.org/W2992488405","https://openalex.org/W4386424163","https://openalex.org/W3180432801","https://openalex.org/W3119196632","https://openalex.org/W3204451748","https://openalex.org/W4321165929","https://openalex.org/W3204082744","https://openalex.org/W4283014629"],"abstract_inverted_index":{"Circular":[0],"RNAs":[1],"(circRNAs),":[2],"a":[3,202,254],"novel":[4],"type":[5],"of":[6,25,32,38,69,132,156,162,205,236],"endogenous":[7],"noncoding":[8],"RNAs,":[9],"have":[10],"been":[11],"identified":[12,230],"as":[13,232,253],"critical":[14],"regulators":[15],"in":[16,27,144,176,182,207,213,222,243],"human":[17],"carcinogenesis.":[18],"Here,":[19],"we":[20],"investigated":[21],"the":[22,28,67,100,114,130,154,160,247],"precise":[23],"actions":[24],"hsa_circ_0009035":[26,133,140,163,185,194,216,231],"progression":[29,210,219,238],"and":[30,43,59,78,89,95,109,147,149,170,174,178,193,211,215,220,239],"radioresistance":[31,155,212,221,240],"cervical":[33],"cancer":[34],"(CC).":[35],"The":[36],"levels":[37],"hsa_circ_0009035,":[39,107],"microRNA":[40],"889-3p":[41],"(miR-889-3p),":[42],"homeobox":[44],"B7":[45],"(HOXB7)":[46],"were":[47,63,80,97,111,126],"detected":[48],"by":[49,99,113,189,224],"quantitative":[50],"real-time":[51],"PCR":[52],"(qRT-PCR)":[53],"or":[54,120],"Western":[55],"blotting.":[56],"RNase":[57],"R":[58],"actinomycin":[60],"D":[61],"assays":[62],"used":[64],"to":[65,128,191],"assess":[66],"stability":[68],"hsa_circ_0009035.":[70],"Cell":[71,83,92],"proliferation,":[72,167],"cell":[73,166],"cycle":[74],"progression,":[75],"apoptosis,":[76],"migration,":[77,168],"invasion":[79],"gauged":[81],"with":[82,153],"Counting":[84],"Kit-8":[85],"(CCK-8),":[86],"flow":[87],"cytometry,":[88],"transwell":[90],"assays.":[91],"colony":[93,101],"formation":[94,102],"survival":[96],"determined":[98],"assay.":[103,123],"Targeted":[104],"correlations":[105],"among":[106],"miR-889-3p,":[108,192],"HOXB7":[110,196,200],"examined":[112],"dual-luciferase":[115],"reporter,":[116],"RNA":[117,121],"immunoprecipitation":[118],"(RIP),":[119],"pulldown":[122],"Animal":[124],"studies":[125],"performed":[127],"evaluate":[129],"impact":[131],"on":[134],"tumor":[135,180],"growth.":[136],"We":[137],"found":[138],"that":[139],"was":[141,151,201],"highly":[142],"expressed":[143],"CC":[145,157,165,209,218,237,259],"tissues":[146],"cells,":[148],"it":[150,171],"associated":[152],"patients.":[158],"Moreover,":[159],"silencing":[161],"inhibited":[164],"invasion,":[169],"enhanced":[172],"apoptosis":[173],"radiosensitivity":[175],"vitro":[177,223],"weakened":[179],"growth":[181],"vivo.":[183],"Mechanistically,":[184],"directly":[186],"targeted":[187],"miR-889-3p":[188,206],"binding":[190],"modulated":[195,217],"expression":[197],"through":[198,245],"miR-889-3p.":[199,225],"functional":[203],"target":[204,257],"regulating":[208],"vitro,":[214],"Our":[226],"current":[227],"study":[228],"first":[229],"an":[233],"important":[234],"regulator":[235],"at":[241],"least":[242],"part":[244],"targeting":[246],"miR-889-3p/HOXB7":[248],"axis,":[249],"highlighting":[250],"its":[251],"significance":[252],"potential":[255],"therapeutic":[256],"for":[258],"treatment.":[260]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-03-29T00:00:00"}