{"id":"https://openalex.org/W3136576465","doi":"https://doi.org/10.15584/ejcem.2021.1.9","title":"Membrane lipids under norm and pathology","display_name":"Membrane lipids under norm and pathology","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3136576465","doi":"https://doi.org/10.15584/ejcem.2021.1.9","mag":"3136576465"},"language":"en","primary_location":{"id":"doi:10.15584/ejcem.2021.1.9","doi":"https://doi.org/10.15584/ejcem.2021.1.9","is_oa":true,"landing_page_url":"https://doi.org/10.15584/ejcem.2021.1.9","pdf_url":null,"source":{"id":"https://openalex.org/S4210221676","display_name":"European Journal of Clinical and Experimental Medicine","issn_l":"2544-1361","issn":["2544-1361","2544-2406"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1","poland-20"],"host_organization":"https://openalex.org/I98559091","host_organization_name":"University of Rzesz\u00f3w","host_organization_lineage":["https://openalex.org/I98559091"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical and Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.15584/ejcem.2021.1.9","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065878254","display_name":"Basheer Abdullah Marzoog","orcid":"https://orcid.org/0000-0001-5507-2413","observed_orcids":["https://orcid.org/0000-0001-5507-2413"]},"institutions":[{"id":"https://openalex.org/I294094635","display_name":"National Research Mordovia State University","ror":"https://ror.org/0262qgk29","country_code":"RU","type":"education","lineage":["https://openalex.org/I294094635"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Basheer Abdullah Marzoog","raw_affiliation_strings":["National Research Mordovia State University, Saransk, Republic of Mordovia, Russia"],"raw_orcid":"https://orcid.org/0000-0001-5507-2413","affiliations":[{"raw_affiliation_string":"National Research Mordovia State University, Saransk, Republic of Mordovia, Russia","institution_ids":["https://openalex.org/I294094635"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035086102","display_name":"Tatyana Ivanovna Vlasova","orcid":"https://orcid.org/0000-0002-2624-6450","observed_orcids":["https://orcid.org/0000-0002-2624-6450"]},"institutions":[{"id":"https://openalex.org/I294094635","display_name":"National Research Mordovia State University","ror":"https://ror.org/0262qgk29","country_code":"RU","type":"education","lineage":["https://openalex.org/I294094635"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Tatyana Ivanovna Vlasova","raw_affiliation_strings":["National Research Mordovia State University, Saransk, Republic of Mordovia, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Research Mordovia State University, Saransk, Republic of Mordovia, Russia","institution_ids":["https://openalex.org/I294094635"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I294094635"],"apc_list":null,"apc_paid":null,"fwci":1.5416,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.83380463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"19","issue":"1","first_page":"59","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.8827999830245972,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.8827999830245972,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.052299998700618744,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.04699999839067459,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/membrane-lipids","display_name":"membrane lipids","score":0.9980000257492065},{"id":"https://openalex.org/keywords/plasma-membrane","display_name":"plasma membrane","score":0.5040000081062317},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.9290000200271606},{"id":"https://openalex.org/keywords/phosphatidylethanolamine","display_name":"phosphatidylethanolamine","score":1.0},{"id":"https://openalex.org/keywords/lipid-asymmetry","display_name":"lipid asymmetry","score":0.8790000081062317},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9760000109672546},{"id":"https://openalex.org/keywords/membrane-lipid-composition","display_name":"membrane lipid composition","score":0.8040000200271606},{"id":"https://openalex.org/keywords/lysosomal-storage-disorders","display_name":"lysosomal storage disease","score":0.7929999828338623},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.9909999966621399},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.8410000205039978}],"concepts":[{"id":"https://openalex.org/C2781170229","wikidata":"https://www.wikidata.org/wiki/Q426095","display_name":"Phosphatidylethanolamine","level":5,"score":0.7723113894462585},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.6958009004592896},{"id":"https://openalex.org/C168240541","wikidata":"https://www.wikidata.org/wiki/Q45948","display_name":"Organelle","level":2,"score":0.5883891582489014},{"id":"https://openalex.org/C107565407","wikidata":"https://www.wikidata.org/wiki/Q6815134","display_name":"Membrane lipids","level":3,"score":0.577263355255127},{"id":"https://openalex.org/C58017582","wikidata":"https://www.wikidata.org/wiki/Q6556376","display_name":"Lipidomics","level":2,"score":0.5490317344665527},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5354528427124023},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5248696208000183},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.5194082260131836},{"id":"https://openalex.org/C2776330855","wikidata":"https://www.wikidata.org/wiki/Q650187","display_name":"Phosphatidylcholine","level":4,"score":0.4955805540084839},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4712826609611511},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4592243731021881},{"id":"https://openalex.org/C2778106830","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Cell membrane","level":3,"score":0.4492841064929962},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.38599693775177},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3372497856616974},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.29686301946640015},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.18993273377418518}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.15584/ejcem.2021.1.9","doi":"https://doi.org/10.15584/ejcem.2021.1.9","is_oa":true,"landing_page_url":"https://doi.org/10.15584/ejcem.2021.1.9","pdf_url":null,"source":{"id":"https://openalex.org/S4210221676","display_name":"European Journal of Clinical and Experimental Medicine","issn_l":"2544-1361","issn":["2544-1361","2544-2406"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1","poland-20"],"host_organization":"https://openalex.org/I98559091","host_organization_name":"University of Rzesz\u00f3w","host_organization_lineage":["https://openalex.org/I98559091"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical and Experimental Medicine","raw_type":"journal-article"},{"id":"pmh:oai:ojs3.journals.ur.edu.pl:article/11876","doi":null,"is_oa":true,"landing_page_url":"https://journals.ur.edu.pl/ejcem/article/view/11876","pdf_url":"https://journals.ur.edu.pl/ejcem/article/download/11876/10709","source":{"id":"https://openalex.org/S4210221676","display_name":"European Journal of Clinical and Experimental Medicine","issn_l":"2544-1361","issn":["2544-1361","2544-2406"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1","poland-20"],"host_organization":"https://openalex.org/I98559091","host_organization_name":"University of Rzesz\u00f3w","host_organization_lineage":["https://openalex.org/I98559091"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"10.15584/ejcem.2021.1","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.15584/ejcem.2021.1.9","doi":"https://doi.org/10.15584/ejcem.2021.1.9","is_oa":true,"landing_page_url":"https://doi.org/10.15584/ejcem.2021.1.9","pdf_url":null,"source":{"id":"https://openalex.org/S4210221676","display_name":"European Journal of Clinical and Experimental Medicine","issn_l":"2544-1361","issn":["2544-1361","2544-2406"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["ddh","doaj","norway-1","poland-20"],"host_organization":"https://openalex.org/I98559091","host_organization_name":"University of Rzesz\u00f3w","host_organization_lineage":["https://openalex.org/I98559091"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Clinical and Experimental Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3136576465.pdf","grobid_xml":"https://content.openalex.org/works/W3136576465.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W258279682","https://openalex.org/W1480235129","https://openalex.org/W1557330668","https://openalex.org/W1560644015","https://openalex.org/W1564344875","https://openalex.org/W1597573955","https://openalex.org/W1976004857","https://openalex.org/W1978069733","https://openalex.org/W1984040540","https://openalex.org/W1989072500","https://openalex.org/W1998845066","https://openalex.org/W1999169071","https://openalex.org/W2001505200","https://openalex.org/W2002057703","https://openalex.org/W2002063618","https://openalex.org/W2003706451","https://openalex.org/W2006928935","https://openalex.org/W2007187686","https://openalex.org/W2025639892","https://openalex.org/W2027110836","https://openalex.org/W2030319696","https://openalex.org/W2038231428","https://openalex.org/W2046138985","https://openalex.org/W2050189794","https://openalex.org/W2052739225","https://openalex.org/W2053283592","https://openalex.org/W2053433344","https://openalex.org/W2055401750","https://openalex.org/W2059890456","https://openalex.org/W2067082060","https://openalex.org/W2070878385","https://openalex.org/W2079462709","https://openalex.org/W2080103294","https://openalex.org/W2086837002","https://openalex.org/W2100021650","https://openalex.org/W2105851320","https://openalex.org/W2121330845","https://openalex.org/W2132763961","https://openalex.org/W2135592618","https://openalex.org/W2149265944","https://openalex.org/W2152692033","https://openalex.org/W2160908368","https://openalex.org/W2193406039","https://openalex.org/W2283311507","https://openalex.org/W2411561471","https://openalex.org/W2552129670","https://openalex.org/W2591719411","https://openalex.org/W2736124309","https://openalex.org/W2770922670","https://openalex.org/W3008199893","https://openalex.org/W4236463097","https://openalex.org/W4242088299"],"related_works":["https://openalex.org/W7057232155","https://openalex.org/W2440948086","https://openalex.org/W2521050851","https://openalex.org/W2583594489","https://openalex.org/W2399338827","https://openalex.org/W1553069063","https://openalex.org/W3199168524","https://openalex.org/W2618845418","https://openalex.org/W2007186542","https://openalex.org/W2507081887"],"abstract_inverted_index":{"Introduction.":[0],"Lipid":[1],"is":[2,184],"an":[3],"essential":[4],"component":[5],"of":[6,17,24,35,48,56,82,91,103,107,135,177],"the":[7,28,32,57,69,83,92,125,131,136,148,175],"cell":[8,33,58,93],"and":[9,15,22,39,54,61,64,79,88,113,144,166,182,202,215],"its":[10],"organelles":[11,55],"membrane.":[12],"The":[13,42,66,85,99,120],"uniqueness":[14],"selectivity":[16],"lipids":[18,50,75,90],"to":[19,164,187,193],"specific":[20,105,209],"functions":[21],"asymmetry":[23],"lipid":[25,108,126,133,213],"distribution":[26],"in":[27,51,59,77,110,180],"organelle\u2019s":[29],"membrane":[30,49,74,94,132],"give":[31],"ability":[34],"being":[36],"highly":[37,162],"qualified":[38],"specified.":[40],"Aim.":[41],"paper":[43,67],"provides":[44],"a":[45,104,117,189],"comprehensive":[46],"review":[47],"different":[52],"tissues":[53],"norm":[60,181],"disease.":[62],"Material":[63],"methods.":[65],"analyzed":[68],"present":[70],"literature":[71],"data":[72],"on":[73,130],"behavior":[76],"physiology":[78],"pathology.":[80],"Analysis":[81],"literature.":[84],"major":[86],"structural":[87],"functional":[89],"are":[95,161],"phosphatidylcholine":[96],">":[97],"phosphatidylethanolamine.":[98],"absence/deficiency":[100],"or":[101],"augmentation":[102],"type":[106],"results":[109],"serious":[111],"defects":[112],"usually":[114],"life-threatening":[115],"with":[116],"permanent":[118],"disability.":[119],"observations":[121],"discussed":[122],"here":[123],"suggest,":[124],"peroxidation":[127,149,165],"severity":[128],"depends":[129],"composition":[134],"cell.":[137],"Some":[138],"tissue":[139],"cells":[140,155],"can":[141],"handle":[142],"lipoperoxidation":[143],"protect":[145],"themselves":[146],"from":[147],"damaging":[150],"products":[151],"better,":[152],"while":[153],"other":[154],"cannot":[156],"compensate.":[157],"Therefore,":[158],"some":[159,203],"organs":[160],"sensitive":[163],"irreversible":[167],"changes":[168],"occur":[169],"rapidly.":[170],"Conclusion.":[171],"To":[172],"sum":[173],"up,":[174],"understanding":[176],"lipid\u2019s":[178],"role":[179],"disease":[183],"clinically":[185],"crucial":[186],"evaluate":[188],"novel":[190],"therapeutic":[191],"target":[192],"treat":[194],"many":[195],"metabolic":[196,200],"disorders":[197,206],"such":[198],"as":[199],"syndrome":[201],"lysosomal":[204],"storage":[205],"via":[207],"targeting":[208],"new":[210],"signaling":[211],"pathways,":[212],"molecules,":[214],"enzymes.":[216]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-03-29T00:00:00"}