{"id":"https://openalex.org/W3136571989","doi":"https://doi.org/10.14341/ket12698","title":"Endogenous and exogenous interferences in thyroid function immunoassays","display_name":"Endogenous and exogenous interferences in thyroid function immunoassays","publication_year":2021,"publication_date":"2021-03-17","ids":{"openalex":"https://openalex.org/W3136571989","doi":"https://doi.org/10.14341/ket12698","mag":"3136571989"},"language":"en","primary_location":{"id":"doi:10.14341/ket12698","doi":"https://doi.org/10.14341/ket12698","is_oa":true,"landing_page_url":"https://doi.org/10.14341/ket12698","pdf_url":"https://www.cet-endojournals.ru/jour/article/download/12698/9827","source":{"id":"https://openalex.org/S2764770592","display_name":"Clinical and experimental thyroidology","issn_l":"1995-5472","issn":["1995-5472","2310-3787"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312880","host_organization_name":"VIDAR-M LLC","host_organization_lineage":["https://openalex.org/P4310312880"],"host_organization_lineage_names":["VIDAR-M LLC"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental thyroidology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cet-endojournals.ru/jour/article/download/12698/9827","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068946220","display_name":"Ekaterina I. Kim","orcid":"https://orcid.org/0000-0001-7879-8495","observed_orcids":["https://orcid.org/0000-0001-7879-8495"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ekaterina I. Kim","raw_affiliation_strings":["Endocrinology Research Centre"],"raw_orcid":"https://orcid.org/0000-0001-7879-8495","affiliations":[{"raw_affiliation_string":"Endocrinology Research Centre","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112630952","display_name":"Diana Dimitrova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diana \u0410. Dimitrova","raw_affiliation_strings":["Endocrinology Research Centre"],"raw_orcid":"https://orcid.org/0000-0002-1359-8297","affiliations":[{"raw_affiliation_string":"Endocrinology Research Centre","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109492508","display_name":"Diana A. Dimitrova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diana A. Dimitrova","raw_affiliation_strings":["Endocrinology Research Centre"],"raw_orcid":"https://orcid.org/0000-0003-2094-8731","affiliations":[{"raw_affiliation_string":"Endocrinology Research Centre","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nino N. Katamadze","orcid":"https://orcid.org/0000-0002-0807-9230","observed_orcids":["https://orcid.org/0000-0002-0807-9230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nino N. Katamadze","raw_affiliation_strings":["Endocrinology Research Centre"],"raw_orcid":"https://orcid.org/0000-0002-0807-9230","affiliations":[{"raw_affiliation_string":"Endocrinology Research Centre","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103979516","display_name":"\u0422\u0430\u043c\u0430\u0440\u0430 \u0421\u0435\u0440\u0433\u0435\u0435\u0432\u043d\u0430 \u0414\u0437\u0430\u043d\u0442\u0438\u0435\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tamara S. Dzantieva","raw_affiliation_strings":["Endocrinology Research Centre"],"raw_orcid":"https://orcid.org/0000-0001-6539-466X","affiliations":[{"raw_affiliation_string":"Endocrinology Research Centre","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1472,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.73537781,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"16","issue":"3","first_page":"16","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.8809000253677368,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.11710000038146973,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immunoassay-interference","display_name":"immunoassay interference","score":0.9369999766349792},{"id":"https://openalex.org/keywords/thyroid-function-tests","display_name":"thyroid function tests","score":0.9359999895095825},{"id":"https://openalex.org/keywords/endogenous-interference","display_name":"endogenous interference","score":0.6380000114440918},{"id":"https://openalex.org/keywords/thyroid-stimulating-hormone","display_name":"thyroid-stimulating hormone","score":0.906000018119812},{"id":"https://openalex.org/keywords/free-thyroxine","display_name":"free thyroxine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/triiodothyronine","display_name":"triiodothyronine","score":0.9800000190734863},{"id":"https://openalex.org/keywords/calcitonin","display_name":"calcitonin","score":0.996999979019165},{"id":"https://openalex.org/keywords/sandwich-immunoassay","display_name":"sandwich immunoassay","score":0.796999990940094},{"id":"https://openalex.org/keywords/competitive-immunoassay","display_name":"competitive immunoassay","score":0.9890000224113464},{"id":"https://openalex.org/keywords/antibody-specificity","display_name":"antibody specificity","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C2780420688","wikidata":"https://www.wikidata.org/wiki/Q759183","display_name":"Immunoassay","level":3,"score":0.7258515357971191},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7156251072883606},{"id":"https://openalex.org/C10390740","wikidata":"https://www.wikidata.org/wiki/Q2282401","display_name":"Analyte","level":2,"score":0.6670140027999878},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.5680341720581055},{"id":"https://openalex.org/C2779627488","wikidata":"https://www.wikidata.org/wiki/Q315860","display_name":"Calcitonin","level":2,"score":0.5413612723350525},{"id":"https://openalex.org/C2778288131","wikidata":"https://www.wikidata.org/wiki/Q327362","display_name":"Triiodothyronine","level":3,"score":0.504308819770813},{"id":"https://openalex.org/C2778840127","wikidata":"https://www.wikidata.org/wiki/Q712838","display_name":"Thyroid function tests","level":3,"score":0.49880194664001465},{"id":"https://openalex.org/C2993291352","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid function","level":3,"score":0.47895437479019165},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.470714271068573},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4535641372203827},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.4411658048629761},{"id":"https://openalex.org/C2993737852","wikidata":"https://www.wikidata.org/wiki/Q712838","display_name":"Free thyroxine","level":4,"score":0.4229556620121002},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.4153063893318176},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3280394375324249},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31745976209640503},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.16303539276123047},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.12913906574249268}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.14341/ket12698","doi":"https://doi.org/10.14341/ket12698","is_oa":true,"landing_page_url":"https://doi.org/10.14341/ket12698","pdf_url":"https://www.cet-endojournals.ru/jour/article/download/12698/9827","source":{"id":"https://openalex.org/S2764770592","display_name":"Clinical and experimental thyroidology","issn_l":"1995-5472","issn":["1995-5472","2310-3787"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312880","host_organization_name":"VIDAR-M LLC","host_organization_lineage":["https://openalex.org/P4310312880"],"host_organization_lineage_names":["VIDAR-M LLC"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental thyroidology","raw_type":"journal-article"},{"id":"mag:3171436804","doi":null,"is_oa":false,"landing_page_url":"https://cyberleninka.ru/article/n/vliyanie-endogennyh-i-ekzogennyh-faktorov-na-immunologicheskie-testy-otsenki-funktsii-schitovidnoy-zhelezy","pdf_url":null,"source":{"id":"https://openalex.org/S4306401404","display_name":"CyberLeninK (CyberLeninka)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0438 \u044d\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u044c\u043d\u0430\u044f \u0442\u0438\u0440\u0435\u043e\u0438\u0434\u043e\u043b\u043e\u0433\u0438\u044f","raw_type":null}],"best_oa_location":{"id":"doi:10.14341/ket12698","doi":"https://doi.org/10.14341/ket12698","is_oa":true,"landing_page_url":"https://doi.org/10.14341/ket12698","pdf_url":"https://www.cet-endojournals.ru/jour/article/download/12698/9827","source":{"id":"https://openalex.org/S2764770592","display_name":"Clinical and experimental thyroidology","issn_l":"1995-5472","issn":["1995-5472","2310-3787"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","russia-white-list-1"],"host_organization":"https://openalex.org/P4310312880","host_organization_name":"VIDAR-M LLC","host_organization_lineage":["https://openalex.org/P4310312880"],"host_organization_lineage_names":["VIDAR-M LLC"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental thyroidology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3136571989.pdf","grobid_xml":"https://content.openalex.org/works/W3136571989.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W138419469","https://openalex.org/W654887237","https://openalex.org/W1592345264","https://openalex.org/W1594241115","https://openalex.org/W1983979158","https://openalex.org/W1986886858","https://openalex.org/W2008114180","https://openalex.org/W2010495551","https://openalex.org/W2021172293","https://openalex.org/W2032008088","https://openalex.org/W2044175562","https://openalex.org/W2048737501","https://openalex.org/W2048878838","https://openalex.org/W2050604996","https://openalex.org/W2060357563","https://openalex.org/W2077012862","https://openalex.org/W2091436795","https://openalex.org/W2100762343","https://openalex.org/W2104182926","https://openalex.org/W2108423868","https://openalex.org/W2135303200","https://openalex.org/W2152464791","https://openalex.org/W2160704266","https://openalex.org/W2167909142","https://openalex.org/W2177853440","https://openalex.org/W2221527183","https://openalex.org/W2276581678","https://openalex.org/W2287424985","https://openalex.org/W2410339740","https://openalex.org/W2518964348","https://openalex.org/W2525086202","https://openalex.org/W2530562429","https://openalex.org/W2556803206","https://openalex.org/W2605903870","https://openalex.org/W2790286389","https://openalex.org/W2791742889","https://openalex.org/W2805481255","https://openalex.org/W2894797166","https://openalex.org/W2908896246","https://openalex.org/W2914831820","https://openalex.org/W2944818580","https://openalex.org/W2958316074","https://openalex.org/W2970013907","https://openalex.org/W3005296891","https://openalex.org/W4252590724"],"related_works":["https://openalex.org/W3171436804","https://openalex.org/W2894797166","https://openalex.org/W1985510710","https://openalex.org/W2100762343","https://openalex.org/W4399921570","https://openalex.org/W2948019498","https://openalex.org/W3113594548","https://openalex.org/W4403896921","https://openalex.org/W3199564164","https://openalex.org/W2096370530"],"abstract_inverted_index":{"Laboratory":[0],"diagnosis":[1],"of":[2,17,32,45,53,63,73,104,114,118,125,132,147,156],"endocrine":[3],"diseases":[4],"has":[5],"undergone":[6],"many":[7],"important":[8],"changes":[9],"over":[10,177],"the":[11,15,43,51,54,61,66,71,92,96,99,105,111,116,123,126,130,133,148,154,175,178],"past":[12,179],"decades,":[13],"despite":[14],"progress":[16],"thyroid":[18,157,161],"function":[19],"immunoassays":[20],"technologies":[21],"interferences":[22,28,150],"cannot":[23],"be":[24,57,82],"completely":[25],"excluded.":[26],"These":[27,79],"can":[29,81,152],"affect":[30,153],"measurement":[31,155],"analyte":[33,93],"which":[34,46],"leads":[35],"to":[36,60,65,89,91,95],"misinterpretation":[37],"and":[38,70,85,94,129,139,166,169],"subsequent":[39],"wrong":[40],"clinical":[41,171],"decisions,":[42],"probability":[44],"is":[47],"about":[48],"1%.":[49],"However,":[50],"scale":[52],"problem":[55,67],"may":[56],"greater":[58],"due":[59],"lack":[62,72],"awareness":[64],"among":[68],"doctors":[69],"laboratory":[74],"screening":[75],"for":[76],"interfering":[77],"factors.":[78],"factors":[80],"both":[83,88],"endogenous":[84],"exogenous,":[86],"bind":[87],"antibodies":[90],"reagent":[97],"in":[98,159,174],"test":[100,127],"system.":[101],"The":[102],"specificity":[103],"immunoassay":[106],"depends":[107],"not":[108],"only":[109],"on":[110,122],"binding":[112],"properties":[113],"antibodies,":[115],"activity":[117],"reagent,":[119],"but":[120],"also":[121],"composition":[124],"system":[128],"format":[131],"methodology":[134],"(non-competitive":[135],"two-site":[136],"or":[137],"\u201csandwich\u201d":[138],"competitive":[140],"assays).":[141],"This":[142],"review":[143],"provides":[144],"a":[145],"description":[146],"main":[149],"that":[151],"hormones,":[158],"particular":[160],"stimulating":[162],"hormone,":[163],"free":[164],"thyroxine":[165],"triiodothyronine,":[167],"calcitonin,":[168],"demonstrates":[170],"cases":[172],"reported":[173],"literature":[176],"few":[180],"years.":[181]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-03-29T00:00:00"}