{"id":"https://openalex.org/W3136065889","doi":"https://doi.org/10.52013/2658-5197-58-1-4","title":"ANALYSIS OF IMMUNOLOGICAL AND VIROLOGICAL RESPONSE IN HIV-POSITIVE PATIENTS DEPENDING ON THE TIME OF DETECTION OF HIV-INFECTION","display_name":"ANALYSIS OF IMMUNOLOGICAL AND VIROLOGICAL RESPONSE IN HIV-POSITIVE PATIENTS DEPENDING ON THE TIME OF DETECTION OF HIV-INFECTION","publication_year":2021,"publication_date":"2021-02-04","ids":{"openalex":"https://openalex.org/W3136065889","doi":"https://doi.org/10.52013/2658-5197-58-1-4","mag":"3136065889"},"language":"en","primary_location":{"id":"doi:10.52013/2658-5197-58-1-4","doi":"https://doi.org/10.52013/2658-5197-58-1-4","is_oa":true,"landing_page_url":"https://doi.org/10.52013/2658-5197-58-1-4","pdf_url":"https://doi.org/10.52013/2658-5197-58-1-4","source":{"id":"https://openalex.org/S4210235848","display_name":"Globus","issn_l":"2658-5197","issn":["2658-5197"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Globus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.52013/2658-5197-58-1-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091839885","display_name":"\u0414. \u041c. \u0423\u0440\u0443\u043d\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0001-6022-8961","observed_orcids":["https://orcid.org/0000-0001-6022-8961"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D.M. Urunova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000800566","display_name":"\u0417. \u0418. \u0410\u0445\u043c\u0435\u0434\u0436\u0430\u043d\u043e\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z.I. Akhmedzhanova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089395112","display_name":"D.A. Karimov","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1302269238","display_name":"Academy of Sciences Republic of Uzbekistan","ror":"https://ror.org/01xgfaw76","country_code":"UZ","type":"government","lineage":["https://openalex.org/I1302269238","https://openalex.org/I4405266844"]}],"countries":["UZ"],"is_corresponding":false,"raw_author_name":"D.A. Karimov","raw_affiliation_strings":["Institute of Immunology and Human Genomics of the Academy of Sciences of the Republic of Uzbekistan","Tashkent State Dental Institute"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Immunology and Human Genomics of the Academy of Sciences of the Republic of Uzbekistan","institution_ids":["https://openalex.org/I1302269238"]},{"raw_affiliation_string":"Tashkent State Dental Institute","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066797746","display_name":"F. R. Kdirbayeva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. R. Kdirbayeva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"1(58)","first_page":"13","last_page":"16"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.9359999895095825},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.8450000286102295},{"id":"https://openalex.org/keywords/cd4-count","display_name":"CD4 count","score":0.796999990940094},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.7799999713897705},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.8949999809265137},{"id":"https://openalex.org/keywords/virological-response","display_name":"virological response","score":0.8790000081062317},{"id":"https://openalex.org/keywords/immunodeficiency","display_name":"immunodeficiency","score":0.6620000004768372},{"id":"https://openalex.org/keywords/aids-risk","display_name":"AIDS risk","score":0.7289999723434448}],"concepts":[{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.7052746415138245},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5753282308578491},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.5053370594978333},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4776014983654022},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.4637124836444855},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4605052173137665},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.07515513896942139},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.52013/2658-5197-58-1-4","doi":"https://doi.org/10.52013/2658-5197-58-1-4","is_oa":true,"landing_page_url":"https://doi.org/10.52013/2658-5197-58-1-4","pdf_url":"https://doi.org/10.52013/2658-5197-58-1-4","source":{"id":"https://openalex.org/S4210235848","display_name":"Globus","issn_l":"2658-5197","issn":["2658-5197"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Globus","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.52013/2658-5197-58-1-4","doi":"https://doi.org/10.52013/2658-5197-58-1-4","is_oa":true,"landing_page_url":"https://doi.org/10.52013/2658-5197-58-1-4","pdf_url":"https://doi.org/10.52013/2658-5197-58-1-4","source":{"id":"https://openalex.org/S4210235848","display_name":"Globus","issn_l":"2658-5197","issn":["2658-5197"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Globus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3136065889.pdf","grobid_xml":"https://content.openalex.org/works/W3136065889.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W1437261270","https://openalex.org/W2027974789","https://openalex.org/W2040185843","https://openalex.org/W2051341179","https://openalex.org/W2121186413","https://openalex.org/W2166653928","https://openalex.org/W2559744539","https://openalex.org/W2948264537"],"related_works":["https://openalex.org/W3118893680","https://openalex.org/W1220085984","https://openalex.org/W4308472332","https://openalex.org/W4384944273","https://openalex.org/W2948264537","https://openalex.org/W2014801327","https://openalex.org/W2740953766","https://openalex.org/W2086310869","https://openalex.org/W1973136419","https://openalex.org/W3012577323"],"abstract_inverted_index":{"ART":[0],"decreases":[1],"the":[2,21,32,40,61],"viral":[3],"load":[4],"to":[5],"a":[6,14,55],"minimum":[7],"level":[8,12],"and":[9],"retains":[10,49],"this":[11,45],"for":[13],"long":[15],"time,":[16],"however,":[17],"an":[18,50,57],"increase":[19],"in":[20],"number":[22],"of":[23,34,37,43,47,60,63],"CD4":[24],"lymphocytes":[25],"is":[26],"not":[27],"always":[28],"determined,":[29],"which":[30],"indicates":[31],"lack":[33],"immunological":[35],"success":[36],"ART.":[38],"Despite":[39],"long-term":[41],"use":[42],"ART,":[44],"category":[46],"patients":[48],"immunodeficiency":[51],"state":[52],"and,":[53],"as":[54],"result,":[56],"increased":[58],"risk":[59],"onset":[62],"AIDS.":[64]},"counts_by_year":[],"updated_date":"2026-09-21T07:43:02.447757","created_date":"2021-03-29T00:00:00"}