{"id":"https://openalex.org/W3135032789","doi":"https://doi.org/10.1016/j.jtbi.2021.110975","title":"Algorithmic asymptotic analysis: Extending the arsenal of cancer immunology modeling","display_name":"Algorithmic asymptotic analysis: Extending the arsenal of cancer immunology modeling","publication_year":2021,"publication_date":"2021-12-06","ids":{"openalex":"https://openalex.org/W3135032789","doi":"https://doi.org/10.1016/j.jtbi.2021.110975","mag":"3135032789","pmid":"https://pubmed.ncbi.nlm.nih.gov/34883121"},"language":"en","primary_location":{"id":"doi:10.1016/j.jtbi.2021.110975","doi":"https://doi.org/10.1016/j.jtbi.2021.110975","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jtbi.2021.110975","pdf_url":null,"source":{"id":"https://openalex.org/S109682412","display_name":"Journal of Theoretical Biology","issn_l":"0022-5193","issn":["0022-5193","1095-8541"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Theoretical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["arxiv","crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://arxiv.org/pdf/2103.02000","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050060748","display_name":"Dimitrios G. Patsatzis","orcid":"https://orcid.org/0000-0001-9840-0018","observed_orcids":["https://orcid.org/0000-0001-9840-0018"]},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]}],"countries":["GR"],"is_corresponding":true,"raw_author_name":"Dimitrios G. Patsatzis","raw_affiliation_strings":["School of Chemical Engineering, National Technical University of Athens, 15772 Athens, Greece. Electronic address: dpatsatzis@mail.ntua.gr","School of Chemical Engineering, National Technical University of Athens, 15772 Athens, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, National Technical University of Athens, 15772 Athens, Greece. Electronic address: dpatsatzis@mail.ntua.gr","institution_ids":["https://openalex.org/I174458059"]},{"raw_affiliation_string":"School of Chemical Engineering, National Technical University of Athens, 15772 Athens, Greece","institution_ids":["https://openalex.org/I174458059"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5050060748"],"corresponding_institution_ids":["https://openalex.org/I174458059"],"apc_list":{"value":2600,"currency":"USD","value_usd":2600},"apc_paid":null,"fwci":0.3546,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.54387668,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"534","issue":null,"first_page":"110975","last_page":"110975"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.8389999866485596},{"id":"https://openalex.org/keywords/computational-singular-perturbation","display_name":"computational singular perturbation","score":0.8769999742507935},{"id":"https://openalex.org/keywords/model-reduction","display_name":"model reduction","score":0.7179999947547913},{"id":"https://openalex.org/keywords/tumor-free-equilibrium","display_name":"tumor-free equilibrium","score":0.8069999814033508},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.7960000038146973},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":1.0},{"id":"https://openalex.org/keywords/circulating-lymphocytes","display_name":"circulating lymphocytes","score":0.9150000214576721},{"id":"https://openalex.org/keywords/multiscale-dynamics","display_name":"multiscale dynamics","score":0.5659999847412109}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5331354141235352},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.48263248801231384},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.47494176030158997},{"id":"https://openalex.org/C165160513","wikidata":"https://www.wikidata.org/wiki/Q7524249","display_name":"Singular perturbation","level":2,"score":0.4723953902721405},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.42218542098999023},{"id":"https://openalex.org/C205147927","wikidata":"https://www.wikidata.org/wiki/Q752718","display_name":"Asymptotic analysis","level":2,"score":0.4164450168609619},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3035971224308014},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.231122225522995},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.21981549263000488},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18698492646217346},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.jtbi.2021.110975","doi":"https://doi.org/10.1016/j.jtbi.2021.110975","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jtbi.2021.110975","pdf_url":null,"source":{"id":"https://openalex.org/S109682412","display_name":"Journal of Theoretical Biology","issn_l":"0022-5193","issn":["0022-5193","1095-8541"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Theoretical Biology","raw_type":"journal-article"},{"id":"pmid:34883121","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34883121","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of theoretical biology","raw_type":"Journal Article"},{"id":"pmh:oai:arXiv.org:2103.02000","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2103.02000","pdf_url":"https://arxiv.org/pdf/2103.02000","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"doi:10.48550/arxiv.2103.02000","doi":"https://doi.org/10.48550/arxiv.2103.02000","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.2103.02000","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:arXiv.org:2103.02000","doi":null,"is_oa":true,"landing_page_url":"http://arxiv.org/abs/2103.02000","pdf_url":"https://arxiv.org/pdf/2103.02000","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":"2331-8422","issn":["2331-8422"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3135032789.pdf","grobid_xml":"https://content.openalex.org/works/W3135032789.grobid-xml"},"referenced_works_count":84,"referenced_works":["https://openalex.org/W177263136","https://openalex.org/W179936242","https://openalex.org/W200565028","https://openalex.org/W420509224","https://openalex.org/W1556059214","https://openalex.org/W1556795282","https://openalex.org/W1595098530","https://openalex.org/W1601679057","https://openalex.org/W1665145671","https://openalex.org/W1966113499","https://openalex.org/W1967663311","https://openalex.org/W1972057495","https://openalex.org/W1979575182","https://openalex.org/W1985345792","https://openalex.org/W1991418841","https://openalex.org/W1993160248","https://openalex.org/W1994295468","https://openalex.org/W1995834760","https://openalex.org/W2001698066","https://openalex.org/W2002304265","https://openalex.org/W2016767879","https://openalex.org/W2021586841","https://openalex.org/W2024056314","https://openalex.org/W2035502912","https://openalex.org/W2035504907","https://openalex.org/W2035982119","https://openalex.org/W2038132127","https://openalex.org/W2040837794","https://openalex.org/W2041210714","https://openalex.org/W2043019977","https://openalex.org/W2044484168","https://openalex.org/W2051755619","https://openalex.org/W2056033381","https://openalex.org/W2056372659","https://openalex.org/W2066671159","https://openalex.org/W2075835338","https://openalex.org/W2084511933","https://openalex.org/W2085107007","https://openalex.org/W2086387602","https://openalex.org/W2091174660","https://openalex.org/W2104010300","https://openalex.org/W2141906015","https://openalex.org/W2143113504","https://openalex.org/W2147342239","https://openalex.org/W2151246207","https://openalex.org/W2155972438","https://openalex.org/W2159287491","https://openalex.org/W2163228402","https://openalex.org/W2167635580","https://openalex.org/W2191139319","https://openalex.org/W2191473923","https://openalex.org/W2192952585","https://openalex.org/W2402373343","https://openalex.org/W2413977353","https://openalex.org/W2465247588","https://openalex.org/W2527772066","https://openalex.org/W2576360213","https://openalex.org/W2616234418","https://openalex.org/W2619891302","https://openalex.org/W2690072531","https://openalex.org/W2761008658","https://openalex.org/W2767326874","https://openalex.org/W2774533844","https://openalex.org/W2775828860","https://openalex.org/W2790488077","https://openalex.org/W2810896552","https://openalex.org/W2889646458","https://openalex.org/W2910271149","https://openalex.org/W2918238426","https://openalex.org/W2943393057","https://openalex.org/W2949273159","https://openalex.org/W2956013039","https://openalex.org/W2958520968","https://openalex.org/W2972649789","https://openalex.org/W2986086925","https://openalex.org/W2988587115","https://openalex.org/W2995674602","https://openalex.org/W4236463097","https://openalex.org/W4236765228","https://openalex.org/W4237990426","https://openalex.org/W4252179889","https://openalex.org/W4292360406","https://openalex.org/W4300934284","https://openalex.org/W4394656083"],"related_works":["https://openalex.org/W7204160615","https://openalex.org/W2037254487","https://openalex.org/W4285722462","https://openalex.org/W3123263386","https://openalex.org/W2107760337","https://openalex.org/W3122652924","https://openalex.org/W3173264156","https://openalex.org/W2046465733","https://openalex.org/W2530626624","https://openalex.org/W2257154498"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-03-15T00:00:00"}
