{"id":"https://openalex.org/W3134874888","doi":"https://doi.org/10.1016/j.ijpharm.2021.120424","title":"The influence of particle size on the application of compression and compaction models for tableting","display_name":"The influence of particle size on the application of compression and compaction models for tableting","publication_year":2021,"publication_date":"2021-02-27","ids":{"openalex":"https://openalex.org/W3134874888","doi":"https://doi.org/10.1016/j.ijpharm.2021.120424","mag":"3134874888","pmid":"https://pubmed.ncbi.nlm.nih.gov/33647406"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijpharm.2021.120424","doi":"https://doi.org/10.1016/j.ijpharm.2021.120424","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijpharm.2021.120424","pdf_url":null,"source":{"id":"https://openalex.org/S131016564","display_name":"International Journal of Pharmaceutics","issn_l":"0378-5173","issn":["0378-5173","1873-3476"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Pharmaceutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113953283","display_name":"Isabell W\u00fcnsch","orcid":"https://orcid.org/0000-0003-0340-9728","observed_orcids":["https://orcid.org/0000-0003-0340-9728"]},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Isabell W\u00fcnsch","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany; Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany; Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057988130","display_name":"Jan Henrik Finke","orcid":"https://orcid.org/0000-0001-6936-9795","observed_orcids":["https://orcid.org/0000-0001-6936-9795"]},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Jan Henrik Finke","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany; Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany. Electronic address: jan.finke@tu-braunschweig.de","Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany; Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany. Electronic address: jan.finke@tu-braunschweig.de","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112666049","display_name":"Edgar John","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283582996","display_name":"Novartis (Switzerland)","ror":"https://ror.org/02f9zrr09","country_code":"CH","type":"company","lineage":["https://openalex.org/I1283582996"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Edgar John","raw_affiliation_strings":["Novartis Pharma AG, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma AG, Basel, Switzerland","institution_ids":["https://openalex.org/I1283582996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064985806","display_name":"Michael Juhnke","orcid":"https://orcid.org/0000-0001-5574-2157","observed_orcids":["https://orcid.org/0000-0001-5574-2157"]},"institutions":[{"id":"https://openalex.org/I1283582996","display_name":"Novartis (Switzerland)","ror":"https://ror.org/02f9zrr09","country_code":"CH","type":"company","lineage":["https://openalex.org/I1283582996"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Juhnke","raw_affiliation_strings":["Novartis Pharma AG, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novartis Pharma AG, Basel, Switzerland","institution_ids":["https://openalex.org/I1283582996"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005901248","display_name":"Arno Kwade","orcid":"https://orcid.org/0000-0002-6348-7309","observed_orcids":["https://orcid.org/0000-0002-6348-7309"]},"institutions":[{"id":"https://openalex.org/I94509681","display_name":"Technische Universit\u00e4t Braunschweig","ror":"https://ror.org/010nsgg66","country_code":"DE","type":"education","lineage":["https://openalex.org/I94509681"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Arno Kwade","raw_affiliation_strings":["Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany; Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany; Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Center of Pharmaceutical Engineering (PVZ), Franz-Liszt-Stra\u00dfe 35A, 38106 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]},{"raw_affiliation_string":"Technische Universit\u00e4t Braunschweig, Institute for Particle Technology, Volkmaroder Stra\u00dfe 5, 38104 Braunschweig, Germany","institution_ids":["https://openalex.org/I94509681"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5057988130"],"corresponding_institution_ids":["https://openalex.org/I94509681"],"apc_list":{"value":3700,"currency":"USD","value_usd":3700},"apc_paid":null,"fwci":5.6919,"has_fulltext":false,"cited_by_count":76,"citation_normalized_percentile":{"value":0.98381096,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"599","issue":null,"first_page":"120424","last_page":"120424"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10615","display_name":"Granular flow and fluidized beds","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10615","display_name":"Granular flow and fluidized beds","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12932","display_name":"Powder Metallurgy Techniques and Materials","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12282","display_name":"Mineral Processing and Grinding","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/particle-size","display_name":"particle size","score":0.9750000238418579},{"id":"https://openalex.org/keywords/powder-compaction","display_name":"powder compaction","score":0.7820000052452087},{"id":"https://openalex.org/keywords/compaction","display_name":"compaction","score":0.8389999866485596},{"id":"https://openalex.org/keywords/tablet-compression","display_name":"tablet compression","score":0.8659999966621399},{"id":"https://openalex.org/keywords/powder-compressibility","display_name":"powder compressibility","score":0.7870000004768372},{"id":"https://openalex.org/keywords/compactability","display_name":"compactibility","score":0.9449999928474426},{"id":"https://openalex.org/keywords/specific-energy","display_name":"specific energy","score":0.6169999837875366},{"id":"https://openalex.org/keywords/elastic-recovery","display_name":"elastic recovery","score":0.9430000185966492},{"id":"https://openalex.org/keywords/tablet-porosity","display_name":"tablet porosity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tablet-tensile-strength","display_name":"tablet tensile strength","score":0.9190000295639038},{"id":"https://openalex.org/keywords/active-pharmaceutical-ingredients","display_name":"active pharmaceutical ingredients","score":0.9039999842643738},{"id":"https://openalex.org/keywords/jkr-model","display_name":"JKR model","score":0.7480000257492065},{"id":"https://openalex.org/keywords/deformation-mechanisms","display_name":"deformation mechanisms","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C2779849058","wikidata":"https://www.wikidata.org/wiki/Q7673462","display_name":"Tableting","level":2,"score":0.9639584422111511},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.7898409366607666},{"id":"https://openalex.org/C196715460","wikidata":"https://www.wikidata.org/wiki/Q1414356","display_name":"Compaction","level":2,"score":0.7538083791732788},{"id":"https://openalex.org/C2779351475","wikidata":"https://www.wikidata.org/wiki/Q417374","display_name":"Microcrystalline cellulose","level":3,"score":0.7033246755599976},{"id":"https://openalex.org/C187530423","wikidata":"https://www.wikidata.org/wiki/Q7140503","display_name":"Particle size","level":2,"score":0.6666667461395264},{"id":"https://openalex.org/C112950240","wikidata":"https://www.wikidata.org/wiki/Q76005","display_name":"Ultimate tensile strength","level":2,"score":0.6597040891647339},{"id":"https://openalex.org/C180016635","wikidata":"https://www.wikidata.org/wiki/Q2712821","display_name":"Compression (physics)","level":2,"score":0.6487675905227661},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.6025615930557251},{"id":"https://openalex.org/C84655787","wikidata":"https://www.wikidata.org/wiki/Q8067817","display_name":"Compressibility","level":2,"score":0.5960235595703125},{"id":"https://openalex.org/C2778517922","wikidata":"https://www.wikidata.org/wiki/Q7140482","display_name":"Particle (ecology)","level":2,"score":0.5229274034500122},{"id":"https://openalex.org/C204366326","wikidata":"https://www.wikidata.org/wiki/Q3027650","display_name":"Deformation (meteorology)","level":2,"score":0.5054967403411865},{"id":"https://openalex.org/C136478896","wikidata":"https://www.wikidata.org/wiki/Q898288","display_name":"Brittleness","level":2,"score":0.4966145157814026},{"id":"https://openalex.org/C6648577","wikidata":"https://www.wikidata.org/wiki/Q622669","display_name":"Porosity","level":2,"score":0.49645596742630005},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.1712045669555664},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.16439011693000793},{"id":"https://openalex.org/C2779251873","wikidata":"https://www.wikidata.org/wiki/Q80294","display_name":"Cellulose","level":2,"score":0.14683866500854492},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.065297931432724},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0618327260017395},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002626","descriptor_name":"Chemistry, Pharmaceutical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011208","descriptor_name":"Powders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013607","descriptor_name":"Tablets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013718","descriptor_name":"Tensile Strength","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016062","descriptor_name":"Porosity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ijpharm.2021.120424","doi":"https://doi.org/10.1016/j.ijpharm.2021.120424","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijpharm.2021.120424","pdf_url":null,"source":{"id":"https://openalex.org/S131016564","display_name":"International Journal of Pharmaceutics","issn_l":"0378-5173","issn":["0378-5173","1873-3476"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Pharmaceutics","raw_type":"journal-article"},{"id":"pmid:33647406","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33647406","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of pharmaceutics","raw_type":"Journal Article"},{"id":"pmh:oai:oak.novartis.com:42687","doi":null,"is_oa":false,"landing_page_url":"https://oak.novartis.com/42687/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400709","display_name":"The Novartis Repository (Novartis)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1283582996","host_organization_name":"Novartis (Switzerland)","host_organization_lineage":["https://openalex.org/I1283582996"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307778","display_name":"Novartis","ror":"https://ror.org/02f9zrr09"},{"id":"https://openalex.org/F4320332736","display_name":"Novartis Pharma","ror":"https://ror.org/0013shd50"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W10522089","https://openalex.org/W188084021","https://openalex.org/W620186277","https://openalex.org/W1558685031","https://openalex.org/W1967246518","https://openalex.org/W1969845646","https://openalex.org/W1972450670","https://openalex.org/W1973027636","https://openalex.org/W1973501867","https://openalex.org/W1979289583","https://openalex.org/W1983099631","https://openalex.org/W1984436548","https://openalex.org/W1989566776","https://openalex.org/W1994418429","https://openalex.org/W1995159622","https://openalex.org/W1997361272","https://openalex.org/W1998089412","https://openalex.org/W2000489776","https://openalex.org/W2008895069","https://openalex.org/W2011254969","https://openalex.org/W2016909003","https://openalex.org/W2017042921","https://openalex.org/W2023814331","https://openalex.org/W2027743140","https://openalex.org/W2027915764","https://openalex.org/W2031018427","https://openalex.org/W2033656688","https://openalex.org/W2034011431","https://openalex.org/W2040081250","https://openalex.org/W2043474738","https://openalex.org/W2046443277","https://openalex.org/W2047662158","https://openalex.org/W2051808157","https://openalex.org/W2053153816","https://openalex.org/W2054836119","https://openalex.org/W2062233325","https://openalex.org/W2073612855","https://openalex.org/W2073981868","https://openalex.org/W2075556981","https://openalex.org/W2079896886","https://openalex.org/W2080918582","https://openalex.org/W2082265828","https://openalex.org/W2087362878","https://openalex.org/W2089216223","https://openalex.org/W2093625676","https://openalex.org/W2095214450","https://openalex.org/W2114396867","https://openalex.org/W2124614417","https://openalex.org/W2139417013","https://openalex.org/W2144307801","https://openalex.org/W2146202010","https://openalex.org/W2164722103","https://openalex.org/W2468015291","https://openalex.org/W2773185776","https://openalex.org/W2807136018","https://openalex.org/W2921251606","https://openalex.org/W2999388243","https://openalex.org/W3037233165","https://openalex.org/W3213293566","https://openalex.org/W6619483527"],"related_works":["https://openalex.org/W7166347052","https://openalex.org/W2999388243","https://openalex.org/W1525888054","https://openalex.org/W4411399757","https://openalex.org/W3145439700","https://openalex.org/W4221107553","https://openalex.org/W7135170371","https://openalex.org/W1558685031","https://openalex.org/W1696688672","https://openalex.org/W4292266455"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":18},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-03-15T00:00:00"}