{"id":"https://openalex.org/W3134594645","doi":"https://doi.org/10.1080/09540105.2021.1874884","title":"A novel polysaccharide from plant fermentation extracts and its immunomodulatory activity in macrophage RAW264.7 cells","display_name":"A novel polysaccharide from plant fermentation extracts and its immunomodulatory activity in macrophage RAW264.7 cells","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W3134594645","doi":"https://doi.org/10.1080/09540105.2021.1874884","mag":"3134594645"},"language":"en","primary_location":{"id":"doi:10.1080/09540105.2021.1874884","doi":"https://doi.org/10.1080/09540105.2021.1874884","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09540105.2021.1874884","pdf_url":null,"source":{"id":"https://openalex.org/S22607022","display_name":"Food and Agricultural Immunology","issn_l":"0954-0105","issn":["0954-0105","1465-3443"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food and Agricultural Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1080/09540105.2021.1874884","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100620853","display_name":"Liang Yan","orcid":"https://orcid.org/0000-0002-1384-4451","observed_orcids":["https://orcid.org/0000-0002-1384-4451"]},"institutions":[{"id":"https://openalex.org/I135237710","display_name":"Zhejiang Normal University","ror":"https://ror.org/01vevwk45","country_code":"CN","type":"education","lineage":["https://openalex.org/I135237710"]},{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yan Liang","raw_affiliation_strings":["University of Electronic Science and Technology of China","Zhejiang Normal University","College of Geography and Environmental Science, Zhejiang Normal University, Jinhua, People's Republic of China","School of Resources and Environment, University of Electronic Science and Technology of China, Chengdu, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Electronic Science and Technology of China","institution_ids":["https://openalex.org/I150229711"]},{"raw_affiliation_string":"Zhejiang Normal University","institution_ids":["https://openalex.org/I135237710"]},{"raw_affiliation_string":"College of Geography and Environmental Science, Zhejiang Normal University, Jinhua, People's Republic of China","institution_ids":["https://openalex.org/I135237710"]},{"raw_affiliation_string":"School of Resources and Environment, University of Electronic Science and Technology of China, Chengdu, People's Republic of China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110445551","display_name":"Chunhua Liu","orcid":"https://orcid.org/0009-0008-8461-710X","observed_orcids":["https://orcid.org/0009-0008-8461-710X"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunhua Liu","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053971433","display_name":"Shuxia Yan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuxia Yan","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101578837","display_name":"Wang Pu","orcid":"https://orcid.org/0000-0002-0409-8450","observed_orcids":["https://orcid.org/0000-0002-0409-8450"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pu Wang","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059177617","display_name":"Binbin Wu","orcid":"https://orcid.org/0000-0002-6862-1554","observed_orcids":["https://orcid.org/0000-0002-6862-1554"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Binbin Wu","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","University of Electronic Science and Technology of China","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","School of Resources and Environment, University of Electronic Science and Technology of China, Chengdu, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"University of Electronic Science and Technology of China","institution_ids":["https://openalex.org/I150229711"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]},{"raw_affiliation_string":"School of Resources and Environment, University of Electronic Science and Technology of China, Chengdu, People's Republic of China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065284133","display_name":"Chengzi Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chengzi Jiang","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009451011","display_name":"Xiaoqing Li","orcid":"https://orcid.org/0000-0001-5781-218X","observed_orcids":["https://orcid.org/0000-0001-5781-218X","https://orcid.org/0000-0001-6453-6005"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoqing Li","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yanwen Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanwen Liu","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]},{"author_position":"last","author":{"id":null,"display_name":"Xiang Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210145761","display_name":"Shenzhen Institutes of Advanced Technology","ror":"https://ror.org/04gh4er46","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiang Li","raw_affiliation_strings":["Shenzhen Institutes of Advanced Technology","Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Institutes of Advanced Technology","institution_ids":["https://openalex.org/I4210145761"]},{"raw_affiliation_string":"Chinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210145761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100620853"],"corresponding_institution_ids":["https://openalex.org/I135237710","https://openalex.org/I150229711","https://openalex.org/I19820366","https://openalex.org/I4210145761"],"apc_list":{"value":1880,"currency":"GBP","value_usd":2306},"apc_paid":{"value":1880,"currency":"GBP","value_usd":2306},"fwci":0.743,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.66103028,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"32","issue":"1","first_page":"54","last_page":"77"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12192","display_name":"Polysaccharides Composition and Applications","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12192","display_name":"Polysaccharides Composition and Applications","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications","score":0.03830000013113022,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.011599999852478504,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polysaccharides","display_name":"polysaccharides","score":0.9079999923706055},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8859999775886536},{"id":"https://openalex.org/keywords/raw-264-7-macrophages","display_name":"RAW 264.7 macrophages","score":0.9539999961853027},{"id":"https://openalex.org/keywords/phagocytic-activity","display_name":"phagocytic activity","score":0.9359999895095825},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9340000152587891},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8629999756813049},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9769999980926514},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":1.0},{"id":"https://openalex.org/keywords/pattern-recognition-receptors","display_name":"pattern recognition receptors","score":0.8840000033378601},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8640000224113464},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.9950000047683716},{"id":"https://openalex.org/keywords/monosaccharide-composition","display_name":"monosaccharide composition","score":0.7540000081062317}],"concepts":[{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.8124001026153564},{"id":"https://openalex.org/C2781236682","wikidata":"https://www.wikidata.org/wiki/Q410015","display_name":"TLR2","level":4,"score":0.7588582038879395},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.5918154120445251},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5906397104263306},{"id":"https://openalex.org/C85265743","wikidata":"https://www.wikidata.org/wiki/Q885458","display_name":"Blot","level":3,"score":0.5743653774261475},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.5405219793319702},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.5284721255302429},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5231612920761108},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4533965587615967},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.42607811093330383},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3994691073894501},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3673168420791626},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.2995484471321106},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.18957015872001648},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15835830569267273},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.13336604833602905},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07127153873443604}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/09540105.2021.1874884","doi":"https://doi.org/10.1080/09540105.2021.1874884","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09540105.2021.1874884","pdf_url":null,"source":{"id":"https://openalex.org/S22607022","display_name":"Food and Agricultural Immunology","issn_l":"0954-0105","issn":["0954-0105","1465-3443"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food and Agricultural Immunology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:ccf0d461b83c45e9844934e24b3ac878","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ccf0d461b83c45e9844934e24b3ac878","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Food and Agricultural Immunology, Vol 32, Iss 1, Pp 54-77 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1080/09540105.2021.1874884","doi":"https://doi.org/10.1080/09540105.2021.1874884","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09540105.2021.1874884","pdf_url":null,"source":{"id":"https://openalex.org/S22607022","display_name":"Food and Agricultural Immunology","issn_l":"0954-0105","issn":["0954-0105","1465-3443"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","jufo-1","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food and Agricultural Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.5,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1193683292","display_name":null,"funder_award_id":"42077395","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4644889070","display_name":null,"funder_award_id":"YCYJ20180507182525623","funder_id":"https://openalex.org/F4320326705","funder_display_name":"Science, Technology and Innovation Commission of Shenzhen Municipality"},{"id":"https://openalex.org/G7403128057","display_name":null,"funder_award_id":"JCYJ20170818164405101","funder_id":"https://openalex.org/F4320326705","funder_display_name":"Science, Technology and Innovation Commission of Shenzhen Municipality"},{"id":"https://openalex.org/G7436171429","display_name":null,"funder_award_id":"81741126","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326705","display_name":"Science, Technology and Innovation Commission of Shenzhen Municipality","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W57763528","https://openalex.org/W642902308","https://openalex.org/W1524470153","https://openalex.org/W1965313627","https://openalex.org/W1968486156","https://openalex.org/W1979123633","https://openalex.org/W1980299508","https://openalex.org/W1988210821","https://openalex.org/W1995418401","https://openalex.org/W2004572978","https://openalex.org/W2009166328","https://openalex.org/W2009235874","https://openalex.org/W2018607958","https://openalex.org/W2025970341","https://openalex.org/W2029844962","https://openalex.org/W2037762765","https://openalex.org/W2038781914","https://openalex.org/W2039156719","https://openalex.org/W2047577972","https://openalex.org/W2048520226","https://openalex.org/W2060957795","https://openalex.org/W2067372231","https://openalex.org/W2072029917","https://openalex.org/W2072178703","https://openalex.org/W2076954791","https://openalex.org/W2085090882","https://openalex.org/W2091360431","https://openalex.org/W2099139884","https://openalex.org/W2101788448","https://openalex.org/W2101799146","https://openalex.org/W2111230647","https://openalex.org/W2111502907","https://openalex.org/W2114501781","https://openalex.org/W2122693757","https://openalex.org/W2133801172","https://openalex.org/W2187699953","https://openalex.org/W2295104051","https://openalex.org/W2298512893","https://openalex.org/W2332265572","https://openalex.org/W2344107174","https://openalex.org/W2400713104","https://openalex.org/W2463475103","https://openalex.org/W2560235460","https://openalex.org/W2613387520","https://openalex.org/W2626978705","https://openalex.org/W2748791398","https://openalex.org/W2794303502","https://openalex.org/W2796057676","https://openalex.org/W2799957723","https://openalex.org/W2898737823","https://openalex.org/W2912797477","https://openalex.org/W2914567675","https://openalex.org/W2985029748","https://openalex.org/W2990050146","https://openalex.org/W2996930423","https://openalex.org/W2999281073","https://openalex.org/W3010197929"],"related_works":["https://openalex.org/W4283706277","https://openalex.org/W2906580573","https://openalex.org/W3045880323","https://openalex.org/W2807984441","https://openalex.org/W4293145324","https://openalex.org/W4206750994","https://openalex.org/W3081443110","https://openalex.org/W3198045095","https://openalex.org/W3097872991","https://openalex.org/W2080126476"],"abstract_inverted_index":{"Plant":[0],"fermentation":[1],"extracts":[2],"(PFEs)":[3],"produced":[4],"from":[5,32],"fermenting":[6],"various":[7],"fruits":[8],"and":[9,50,58,82,90,106,114,124,131,147],"vegetables":[10],"by":[11],"microorganisms":[12],"have":[13],"traditionally":[14],"been":[15],"consumed":[16],"as":[17],"healthy":[18],"beverages":[19],"in":[20,36,52],"Asia.":[21],"Herein,":[22],"the":[23,59,76,97,120,129,140,144],"immunomodulatory":[24,141],"activities":[25],"of":[26,46,56,79,100,122,143],"a":[27,53],"novel":[28],"polysaccharide":[29,145],"(AP)":[30],"isolated":[31],"PFE":[33],"were":[34,126],"examined":[35],"RAW264.7":[37,80],"cells.":[38],"The":[39],"results":[40],"showed":[41,70],"that":[42,71,119],"AP":[43,72,93,146],"was":[44,63],"composed":[45],"Rha,":[47],"Xyl,":[48],"Man":[49],"Glu":[51],"molar":[54],"ratio":[55],"9.7:27.6:8.81:53.85":[57],"average":[60],"molecular":[61],"weight":[62],"4.81":[64],"\u00d7":[65],"105":[66],"Da.":[67],"Our":[68],"data":[69],"could":[73,94],"significantly":[74,95],"enhance":[75],"phagocytic":[77],"activity":[78],"cells":[81],"their":[83],"ability":[84],"to":[85,138],"release":[86],"NO,":[87],"TNF-\u03b1,":[88],"IL-6":[89],"IL-10.":[91],"Furthermore,":[92],"up-regulate":[96],"mRNA":[98],"expression":[99],"iNOS,":[101],"cytokines":[102],"(TNF-\u03b1,":[103],"IL-6,":[104],"IL-10)":[105],"pattern":[107],"recognition":[108],"receptors":[109],"(TLR2,":[110],"MR,":[111],"GR,":[112],"CR3":[113],"SR).":[115],"Western":[116],"blotting":[117],"demonstrated":[118],"regulation":[121],"NO":[123],"TNF-\u03b1":[125],"mediated":[127],"through":[128],"NF-\u03baB":[130],"MAPK":[132],"signalling":[133],"pathways.":[134],"These":[135],"findings":[136],"helped":[137],"elucidate":[139],"properties":[142],"PFE.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-03-15T00:00:00"}
