{"id":"https://openalex.org/W3133800993","doi":"https://doi.org/10.1038/s41586-021-03309-5","title":"Actin cables and comet tails organize mitochondrial networks in mitosis","display_name":"Actin cables and comet tails organize mitochondrial networks in mitosis","publication_year":2021,"publication_date":"2021-03-03","ids":{"openalex":"https://openalex.org/W3133800993","doi":"https://doi.org/10.1038/s41586-021-03309-5","mag":"3133800993","pmid":"https://pubmed.ncbi.nlm.nih.gov/33658713","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7990722"},"language":"en","primary_location":{"id":"doi:10.1038/s41586-021-03309-5","doi":"https://doi.org/10.1038/s41586-021-03309-5","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41586-021-03309-5","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7990722","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Andrew S. Moore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew S. Moore","raw_affiliation_strings":["Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017461882","display_name":"Stephen M. Coscia","orcid":"https://orcid.org/0000-0002-4113-8802","observed_orcids":["https://orcid.org/0000-0002-4113-8802"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen M. Coscia","raw_affiliation_strings":["Cell and Molecular Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":"https://orcid.org/0000-0002-4113-8802","affiliations":[{"raw_affiliation_string":"Cell and Molecular Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034923129","display_name":"Cory L. Simpson","orcid":"https://orcid.org/0000-0002-3933-6404","observed_orcids":["https://orcid.org/0000-0002-3933-6404"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cory L. Simpson","raw_affiliation_strings":["Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043802434","display_name":"Fabian E. Ortega","orcid":"https://orcid.org/0000-0002-3782-4762","observed_orcids":["https://orcid.org/0000-0002-3782-4762"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fabian E. Ortega","raw_affiliation_strings":["Department of Biochemistry, Stanford University, Stanford, CA, USA","Department of Biochemistry, Stanford University,Stanford,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Biochemistry, Stanford University,Stanford,USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035521739","display_name":"Eric C. Wait","orcid":"https://orcid.org/0000-0002-1614-9219","observed_orcids":["https://orcid.org/0000-0002-1614-9219"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric C. Wait","raw_affiliation_strings":["Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042915381","display_name":"John M. Heddleston","orcid":"https://orcid.org/0000-0002-9289-4114","observed_orcids":["https://orcid.org/0000-0002-9289-4114"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John M. Heddleston","raw_affiliation_strings":["Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA"],"raw_orcid":"https://orcid.org/0000-0002-9289-4114","affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012415712","display_name":"Jeffrey Nirschl","orcid":"https://orcid.org/0000-0001-6857-341X","observed_orcids":["https://orcid.org/0000-0001-6857-341X"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey J. Nirschl","raw_affiliation_strings":["Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":"https://orcid.org/0000-0001-6857-341X","affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083830984","display_name":"Christopher John Obara","orcid":"https://orcid.org/0000-0003-1028-6076","observed_orcids":["https://orcid.org/0000-0003-1028-6076"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher J. Obara","raw_affiliation_strings":["Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069040826","display_name":"Pedro Guedes-Dias","orcid":"https://orcid.org/0000-0003-0992-5141","observed_orcids":["https://orcid.org/0000-0003-0992-5141"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Pedro Guedes-Dias","raw_affiliation_strings":["Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","Institute of Neuronal Cell Biology, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":"https://orcid.org/0000-0003-0992-5141","affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Institute of Neuronal Cell Biology, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072866258","display_name":"C. Alexander Boecker","orcid":"https://orcid.org/0000-0001-9701-5273","observed_orcids":["https://orcid.org/0000-0001-9701-5273"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Alexander Boecker","raw_affiliation_strings":["Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":"https://orcid.org/0000-0001-9701-5273","affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047668731","display_name":"Teng\u2010Leong Chew","orcid":"https://orcid.org/0000-0002-3139-7560","observed_orcids":["https://orcid.org/0000-0002-3139-7560"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teng-Leong Chew","raw_affiliation_strings":["Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA"],"raw_orcid":"https://orcid.org/0000-0002-3139-7560","affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078436996","display_name":"Julie A. Theriot","orcid":"https://orcid.org/0000-0002-2334-2535","observed_orcids":["https://orcid.org/0000-0002-2334-2535"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie A. Theriot","raw_affiliation_strings":["Department of Biology, University of Washington, Seattle, WA, USA","Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA","Howard Hughes Medical Institute, University of Washington, Seattle, USA"],"raw_orcid":"https://orcid.org/0000-0002-2334-2535","affiliations":[{"raw_affiliation_string":"Department of Biology, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I201448701"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, University of Washington, Seattle, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000877747","display_name":"Jennifer Lippincott\u2010Schwartz","orcid":"https://orcid.org/0000-0002-8601-3501","observed_orcids":["https://orcid.org/0000-0002-8601-3501"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Lippincott-Schwartz","raw_affiliation_strings":["Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA"],"raw_orcid":"https://orcid.org/0000-0002-8601-3501","affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]},{"raw_affiliation_string":"Howard Hughes Medical Institute Janelia Research Campus, Ashburn, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075390520","display_name":"Erika L.F. Holzbaur","orcid":"https://orcid.org/0000-0001-5389-4114","observed_orcids":["https://orcid.org/0000-0001-5389-4114"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Erika L. F. Holzbaur","raw_affiliation_strings":["Cell and Molecular Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu","Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu","The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA"],"raw_orcid":"https://orcid.org/0000-0001-5389-4114","affiliations":[{"raw_affiliation_string":"Cell and Molecular Biology Graduate Group, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"The Pennsylvania Muscle Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5075390520"],"corresponding_institution_ids":["https://openalex.org/I79576946"],"apc_list":{"value":11390,"currency":"USD","value_usd":11390},"apc_paid":null,"fwci":14.8768,"has_fulltext":false,"cited_by_count":184,"citation_normalized_percentile":{"value":0.99785939,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"591","issue":"7851","first_page":"659","last_page":"664"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.02500000037252903,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/actin-cables","display_name":"actin cables","score":0.7910000085830688},{"id":"https://openalex.org/keywords/mitochondrial-inheritance","display_name":"mitochondrial inheritance","score":0.8169999718666077},{"id":"https://openalex.org/keywords/mitochondrial-segregation","display_name":"mitochondrial segregation","score":0.6150000095367432},{"id":"https://openalex.org/keywords/mitosis","display_name":"mitosis","score":0.8370000123977661},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.7820000052452087},{"id":"https://openalex.org/keywords/endoplasmic-reticulum","display_name":"endoplasmic reticulum","score":0.8489999771118164},{"id":"https://openalex.org/keywords/cytokinesis","display_name":"cytokinesis","score":0.7680000066757202},{"id":"https://openalex.org/keywords/organelle-inheritance","display_name":"organelle inheritance","score":0.7039999961853027},{"id":"https://openalex.org/keywords/symmetric-cell-division","display_name":"symmetric cell division","score":0.6690000295639038},{"id":"https://openalex.org/keywords/mitochondrial-motility","display_name":"mitochondrial motility","score":0.5090000033378601},{"id":"https://openalex.org/keywords/actin-filament-assembly","display_name":"actin filament assembly","score":0.4309999942779541}],"concepts":[{"id":"https://openalex.org/C45472230","wikidata":"https://www.wikidata.org/wiki/Q1447198","display_name":"Cytokinesis","level":4,"score":0.7760096788406372},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7490707039833069},{"id":"https://openalex.org/C93304396","wikidata":"https://www.wikidata.org/wiki/Q14763008","display_name":"Mitosis","level":2,"score":0.6550423502922058},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5727435350418091},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5459995269775391},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.4997420310974121},{"id":"https://openalex.org/C85813293","wikidata":"https://www.wikidata.org/wiki/Q188909","display_name":"Cell division","level":3,"score":0.49766042828559875},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.4510393440723419},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.4252222180366516},{"id":"https://openalex.org/C168240541","wikidata":"https://www.wikidata.org/wiki/Q45948","display_name":"Organelle","level":2,"score":0.4220181703567505},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.4201492667198181},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.41673314571380615},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2848275303840637},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2764649987220764},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09940165281295776}],"mesh":[{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000199","descriptor_name":"Actins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008938","descriptor_name":"Mitosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048749","descriptor_name":"Cytokinesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41586-021-03309-5","doi":"https://doi.org/10.1038/s41586-021-03309-5","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41586-021-03309-5","pdf_url":null,"source":{"id":"https://openalex.org/S137773608","display_name":"Nature","issn_l":"0028-0836","issn":["0028-0836","1476-4687"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"journal-article"},{"id":"pmid:33658713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33658713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7990722","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7990722","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nature","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:nature:v:591:y:2021:i:7851:d:10.1038_s41586-021-03309-5","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41586-021-03309-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7990722","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7990722","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nature","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1819279956","display_name":"Pathogenic Mechanisms of Reduced Transport Initiation in Perry Syndrome","funder_award_id":"F30NS092227","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3924362601","display_name":"Regulation of mitochondrial dynamics and homeostasis by cyclic actin assembly/disassembly","funder_award_id":"F31GM123644","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5802534066","display_name":"Role of autophagy in epidermal differentiation and homeostasis","funder_award_id":"K08AR075846","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G7896908894","display_name":"Integrative mechanisms of organelle dynamics from the atomic-to-cellular level","funder_award_id":"RM1GM136511","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7928989251","display_name":"Actin-based motility of a bacterial pathogen","funder_award_id":"R37AI036929","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000895572","display_name":"Molecular Mechanisms of Axonal Transport and Organelle Dynamics","funder_award_id":"R35GM126950","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000906581","display_name":"Penn Skin Biology and Diseases Resource-based Center","funder_award_id":"P30AR069589","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W133811466","https://openalex.org/W1568630971","https://openalex.org/W1779577685","https://openalex.org/W1897507705","https://openalex.org/W1976944340","https://openalex.org/W1979497973","https://openalex.org/W1985390453","https://openalex.org/W1986141440","https://openalex.org/W1988051514","https://openalex.org/W1988282769","https://openalex.org/W1997982747","https://openalex.org/W2016029650","https://openalex.org/W2053270078","https://openalex.org/W2054115583","https://openalex.org/W2063411991","https://openalex.org/W2064398546","https://openalex.org/W2065490663","https://openalex.org/W2068876164","https://openalex.org/W2097352228","https://openalex.org/W2099573412","https://openalex.org/W2105389175","https://openalex.org/W2117411464","https://openalex.org/W2126041521","https://openalex.org/W2126267296","https://openalex.org/W2127901427","https://openalex.org/W2138760860","https://openalex.org/W2145631189","https://openalex.org/W2146473275","https://openalex.org/W2151613988","https://openalex.org/W2152157469","https://openalex.org/W2156155065","https://openalex.org/W2167279371","https://openalex.org/W2317883772","https://openalex.org/W2397071937","https://openalex.org/W2509551770","https://openalex.org/W2525948328","https://openalex.org/W2529052661","https://openalex.org/W2624103631","https://openalex.org/W2770938857","https://openalex.org/W2803819386","https://openalex.org/W2883224062","https://openalex.org/W2898224116","https://openalex.org/W2946334536","https://openalex.org/W2951280848","https://openalex.org/W2953588232","https://openalex.org/W2975634117","https://openalex.org/W3005141459","https://openalex.org/W3015646000","https://openalex.org/W3090978739","https://openalex.org/W3132318166"],"related_works":["https://openalex.org/W3162219120","https://openalex.org/W3154725127","https://openalex.org/W3136210357","https://openalex.org/W4396512048","https://openalex.org/W2063713887","https://openalex.org/W1985390453","https://openalex.org/W2047979211","https://openalex.org/W3003873380","https://openalex.org/W2170695367","https://openalex.org/W7135345689"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":24},{"year":2025,"cited_by_count":46},{"year":2024,"cited_by_count":37},{"year":2023,"cited_by_count":36},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":15}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-03-15T00:00:00"}