{"id":"https://openalex.org/W3133734976","doi":"https://doi.org/10.1158/1557-3265.adi21-po-068","title":"Abstract PO-068: Developing ovarian cancer sensors using molecular perceptron","display_name":"Abstract PO-068: Developing ovarian cancer sensors using molecular perceptron","publication_year":2021,"publication_date":"2021-03-01","ids":{"openalex":"https://openalex.org/W3133734976","doi":"https://doi.org/10.1158/1557-3265.adi21-po-068","mag":"3133734976"},"language":"en","primary_location":{"id":"doi:10.1158/1557-3265.adi21-po-068","doi":"https://doi.org/10.1158/1557-3265.adi21-po-068","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1557-3265.adi21-po-068","pdf_url":null,"source":{"id":"https://openalex.org/S183149254","display_name":"Clinical Cancer Research","issn_l":"1078-0432","issn":["1078-0432","1557-3265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Cancer Research","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027512284","display_name":"Zvi A Yaari","orcid":"https://orcid.org/0000-0002-1889-1994","observed_orcids":["https://orcid.org/0000-0002-1889-1994"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zvi Yaari","raw_affiliation_strings":["1Memorial Sloan Kettering Cancer Center, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Memorial Sloan Kettering Cancer Center, New York, NY,","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101624033","display_name":"Yoona Yang","orcid":"https://orcid.org/0000-0002-7446-8816","observed_orcids":["https://orcid.org/0000-0002-7446-8816"]},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoona Yang","raw_affiliation_strings":["2Lehigh University, Bethlehem, PA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Lehigh University, Bethlehem, PA,","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003116978","display_name":"Anand Jagota","orcid":"https://orcid.org/0000-0002-0779-0880","observed_orcids":["https://orcid.org/0000-0002-0779-0880"]},"institutions":[{"id":"https://openalex.org/I186143895","display_name":"Lehigh University","ror":"https://ror.org/012afjb06","country_code":"US","type":"education","lineage":["https://openalex.org/I186143895"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anand Jagota","raw_affiliation_strings":["2Lehigh University, Bethlehem, PA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Lehigh University, Bethlehem, PA,","institution_ids":["https://openalex.org/I186143895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006964660","display_name":"Ming Zheng","orcid":"https://orcid.org/0000-0002-8058-1348","observed_orcids":["https://orcid.org/0000-0002-8058-1348"]},"institutions":[{"id":"https://openalex.org/I1321296531","display_name":"National Institute of Standards and Technology","ror":"https://ror.org/05xpvk416","country_code":"US","type":"government","lineage":["https://openalex.org/I1321296531","https://openalex.org/I1343035065"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ming Zheng","raw_affiliation_strings":["3NIST, Gaithersburg, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3NIST, Gaithersburg, MD","institution_ids":["https://openalex.org/I1321296531"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037355958","display_name":"Daniel A. Heller","orcid":"https://orcid.org/0000-0002-6866-0000","observed_orcids":["https://orcid.org/0000-0002-6866-0000"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel A. Heller","raw_affiliation_strings":["1Memorial Sloan Kettering Cancer Center, New York, NY,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Memorial Sloan Kettering Cancer Center, New York, NY,","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"5_Supplement","first_page":"PO","last_page":"068"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.4284999966621399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.4284999966621399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.3474000096321106,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0364999994635582,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.996999979019165},{"id":"https://openalex.org/keywords/early-cancer-detection","display_name":"early cancer detection","score":0.7400000095367432},{"id":"https://openalex.org/keywords/carbon-nanotube-sensors","display_name":"carbon nanotube sensors","score":0.7940000295639038},{"id":"https://openalex.org/keywords/single-walled-carbon-nanotubes","display_name":"single-walled carbon nanotubes","score":0.9819999933242798},{"id":"https://openalex.org/keywords/implantable-sensors","display_name":"implantable sensors","score":0.7440000176429749},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.8410000205039978},{"id":"https://openalex.org/keywords/artificial-intelligence-in-diagnostics","display_name":"artificial intelligence in diagnostics","score":0.4650000035762787}],"concepts":[{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.8698306083679199},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.6477512121200562},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6147780418395996},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.595250129699707},{"id":"https://openalex.org/C179717631","wikidata":"https://www.wikidata.org/wiki/Q2991667","display_name":"Multilayer perceptron","level":3,"score":0.42543670535087585},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.41718870401382446},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4134975075721741},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.41262170672416687},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2078392505645752},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1835973560810089},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11540469527244568},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.07102492451667786},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1557-3265.adi21-po-068","doi":"https://doi.org/10.1158/1557-3265.adi21-po-068","is_oa":false,"landing_page_url":"https://doi.org/10.1158/1557-3265.adi21-po-068","pdf_url":null,"source":{"id":"https://openalex.org/S183149254","display_name":"Clinical Cancer Research","issn_l":"1078-0432","issn":["1078-0432","1557-3265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Cancer Research","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3024203664","https://openalex.org/W3118139554","https://openalex.org/W4285497361","https://openalex.org/W2802154375","https://openalex.org/W4221014558","https://openalex.org/W2970940880","https://openalex.org/W2954461188","https://openalex.org/W2040621160","https://openalex.org/W2801617804","https://openalex.org/W2807029941"],"abstract_inverted_index":{"Abstract":[0],"Ovarian":[1],"cancer":[2,28,68,107,147],"patient":[3],"prognosis":[4],"and":[5,73,88,97,165],"quality":[6],"of":[7,26,49,90,99,125,155],"life":[8],"are":[9,30,39],"significantly":[10],"affected":[11],"by":[12],"the":[13,84,123,129,156],"failure":[14],"to":[15,58,70,104,117,128],"accurately":[16],"diagnose":[17],"disease":[18],"at":[19,32],"early":[20],"stage.":[21],"Currently,":[22],"less":[23],"than":[24,47],"15%":[25],"ovarian":[27,53,67,106,146],"patients":[29],"diagnosed":[31,51],"stage":[33],"1,":[34],"when":[35],"5-year":[36],"survival":[37],"rates":[38],"near":[40],"93%.":[41],"Early":[42],"detection":[43],"may":[44],"save":[45],"more":[46],"80%":[48],"women":[50],"with":[52],"cancer.":[54],"Our":[55],"goal":[56],"is":[57],"develop":[59],"clinical":[60],"long-term":[61],"implantable":[62],"carbon":[63,92],"nanotube-based":[64],"sensors":[65,81,148],"for":[66],"biomarkers":[69,108,127],"transiently":[71],"detect":[72,105,118],"monitor":[74],"their":[75],"levels":[76],"in":[77,109],"patients.":[78],"The":[79],"proposed":[80],"will":[82],"harness":[83],"unique":[85],"optical":[86],"properties":[87],"sensitivity":[89,96],"single-walled":[91],"nanotubes.":[93],"To":[94],"improve":[95],"specificity":[98],"such":[100],"sensors,":[101],"previously":[102],"developed":[103],"vivo,":[110],"we":[111],"used":[112],"molecular":[113,150],"perceptron\u2014data":[114],"analytics-based":[115],"methods":[116],"specific":[119],"spectroscopic":[120],"fingerprints":[121],"from":[122],"binding":[124],"protein":[126],"nanotube":[130],"surface.":[131],"Citation":[132],"Format:":[133],"Zvi":[134],"Yaari,":[135],"Yoona":[136],"Yang,":[137],"Anand":[138],"Jagota,":[139],"Ming":[140],"Zheng,":[141],"Daniel":[142],"A.":[143],"Heller.":[144],"Developing":[145],"using":[149],"perceptron":[151],"[abstract].":[152],"In:":[153],"Proceedings":[154],"AACR":[157],"Virtual":[158],"Special":[159],"Conference":[160],"on":[161],"Artificial":[162],"Intelligence,":[163],"Diagnosis,":[164],"Imaging;":[166],"2021":[167],"Jan":[168],"13-14.":[169],"Philadelphia":[170],"(PA):":[171],"AACR;":[172],"Clin":[173],"Cancer":[174],"Res":[175],"2021;27(5_Suppl):Abstract":[176],"nr":[177],"PO-068.":[178]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2021-03-15T00:00:00"}