{"id":"https://openalex.org/W3133624601","doi":"https://doi.org/10.5530/pj.2021.13.48","title":"Characterization and Acute Toxicity Bioactive Compound Canning Waste of Lemuru Fish Oil as Potential Immunomodulator","display_name":"Characterization and Acute Toxicity Bioactive Compound Canning Waste of Lemuru Fish Oil as Potential Immunomodulator","publication_year":2020,"publication_date":"2020-03-04","ids":{"openalex":"https://openalex.org/W3133624601","doi":"https://doi.org/10.5530/pj.2021.13.48","mag":"3133624601"},"language":"en","primary_location":{"id":"doi:10.5530/pj.2021.13.48","doi":"https://doi.org/10.5530/pj.2021.13.48","is_oa":true,"landing_page_url":"https://doi.org/10.5530/pj.2021.13.48","pdf_url":null,"source":{"id":"https://openalex.org/S2764874817","display_name":"Pharmacognosy Journal","issn_l":"0975-3575","issn":["0975-3575"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4360969232","host_organization_name":"EManuscript Services","host_organization_lineage":["https://openalex.org/P4360969232"],"host_organization_lineage_names":["EManuscript Services"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacognosy Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5530/pj.2021.13.48","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079326660","display_name":"Dian Widya Damaiyanti","orcid":"https://orcid.org/0000-0001-8894-074X","observed_orcids":["https://orcid.org/0000-0001-8894-074X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Damaiyanti Damaiyanti DW","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076750557","display_name":"Sari Sari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sari Sari R.P","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110747045","display_name":"Muwarmanti Muwarmanti D","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Muwarmanti Muwarmanti D","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079326660"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3073,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.54542184,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"13","issue":"2","first_page":"376","last_page":"382"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.013899999670684338,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lemuru-fish-oil","display_name":"lemuru fish oil","score":0.9440000057220459},{"id":"https://openalex.org/keywords/polyunsaturated-fatty-acids","display_name":"polyunsaturated fatty acids","score":0.9089999794960022},{"id":"https://openalex.org/keywords/eicosapentaenoic-acid","display_name":"eicosapentaenoic acid","score":0.9959999918937683},{"id":"https://openalex.org/keywords/docosahexaenoic-acid","display_name":"docosahexaenoic acid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/acute-toxicity","display_name":"acute toxicity","score":0.9559999704360962},{"id":"https://openalex.org/keywords/immunomodulators","display_name":"immunomodulators","score":0.8709999918937683},{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.878000020980835},{"id":"https://openalex.org/keywords/liver-histopathology","display_name":"liver histopathology","score":0.7789999842643738},{"id":"https://openalex.org/keywords/fish-waste-utilization","display_name":"fish waste utilization","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.697470486164093},{"id":"https://openalex.org/C116263406","wikidata":"https://www.wikidata.org/wiki/Q3299024","display_name":"Acute toxicity","level":3,"score":0.6481705904006958},{"id":"https://openalex.org/C2779946292","wikidata":"https://www.wikidata.org/wiki/Q1786125","display_name":"Fish oil","level":3,"score":0.6318671703338623},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.6211814880371094},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4552026391029358},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.4192698895931244},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.3112105131149292},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2997269630432129},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0689171850681305}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5530/pj.2021.13.48","doi":"https://doi.org/10.5530/pj.2021.13.48","is_oa":true,"landing_page_url":"https://doi.org/10.5530/pj.2021.13.48","pdf_url":null,"source":{"id":"https://openalex.org/S2764874817","display_name":"Pharmacognosy Journal","issn_l":"0975-3575","issn":["0975-3575"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4360969232","host_organization_name":"EManuscript Services","host_organization_lineage":["https://openalex.org/P4360969232"],"host_organization_lineage_names":["EManuscript Services"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacognosy Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.5530/pj.2021.13.48","doi":"https://doi.org/10.5530/pj.2021.13.48","is_oa":true,"landing_page_url":"https://doi.org/10.5530/pj.2021.13.48","pdf_url":null,"source":{"id":"https://openalex.org/S2764874817","display_name":"Pharmacognosy Journal","issn_l":"0975-3575","issn":["0975-3575"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4360969232","host_organization_name":"EManuscript Services","host_organization_lineage":["https://openalex.org/P4360969232"],"host_organization_lineage_names":["EManuscript Services"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacognosy Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W24514603","https://openalex.org/W1596389679","https://openalex.org/W2028744237","https://openalex.org/W2051309487","https://openalex.org/W2130735505","https://openalex.org/W2135920277","https://openalex.org/W2146951696","https://openalex.org/W2152199137","https://openalex.org/W2167053420","https://openalex.org/W2342678784","https://openalex.org/W2906508419"],"related_works":["https://openalex.org/W4390841139","https://openalex.org/W3191269581","https://openalex.org/W7094571208","https://openalex.org/W4211242556","https://openalex.org/W4408210526","https://openalex.org/W2008418076","https://openalex.org/W2133919431","https://openalex.org/W2143230785","https://openalex.org/W7146106006","https://openalex.org/W2884147675"],"abstract_inverted_index":{"Background:":[0],"Poly":[1,147],"Unsaturated":[2,148],"Fatty":[3,149],"Acids":[4,150],"have":[5],"beneficial":[6],"effects":[7],"as":[8,29],"an":[9,135,151],"immunomodulator":[10],"for":[11,63,94,100],"periodontitis":[12],"therapy.":[13],"Lipid":[14],"studies":[15],"show":[16,134],"that":[17,43],"fish":[18,36,42,61],"can":[19],"be":[20],"a":[21,145],"unique":[22],"source":[23],"of":[24,41,59,125,169],"polyunsaturated":[25],"fatty":[26],"acids":[27],"such":[28],"eicosapentaenoic":[30,114],"acid":[31,115],"and":[32,56,98,116,160],"docosahexaenoic":[33],"acid.":[34],"Lemuru":[35,109,141],"(Sardinella":[37],"longicep)":[38],"is":[39,172],"one":[40],"abbundant":[44],"in":[45,65],"Indonesia.":[46],"Purpose:":[47],"This":[48],"study":[49,70],"aims":[50],"to":[51,133],"find":[52],"out":[53],"the":[54,123,161,166,170],"characterization":[55,69],"acute":[57,157],"toxicity":[58,83,121,158],"lemuru":[60,87],"oil":[62,111,143],"using":[64,73],"dental":[66],"treatment.":[67],"Methods:":[68],"was":[71,155],"tested":[72],"capillary":[74],"gas":[75],"chromatography":[76],"coupled":[77],"method":[78],"with":[79,89],"flame":[80],"ionization.":[81],"Acute":[82,120],"performed":[84],"by":[85],"given":[86],"orally":[88],"dose":[90,138,163],"174.1-917.3mg/20g":[91],"mice":[92],"weight":[93],"24":[95],"hours":[96,105],"observation":[97,106],"sacrificed":[99],"histopathology,":[101],"meanwhile":[102],"groups":[103],"96":[104],"continued.":[107],"Results:":[108],"Fish":[110,142],"contains":[112],"14.5%":[113],"13,2%":[117],"Docosahexaenoic":[118],"Acid.":[119],"showed":[122],"percentage":[124],"death":[126],"below":[127],"50%,":[128],"however,":[129],"liver":[130,171],"structure":[131,168],"start":[132],"effect":[136],"on":[137],"355.3mg/20gr":[139],"Conclusion:":[140],"had":[144],"component":[146],"potential":[152],"immunomodulator.":[153],"There":[154],"no":[156],"found":[159],"maximum":[162],"without":[164],"changing":[165],"microscopic":[167],"174.1mg":[173],"/":[174],"20gr.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-03-15T00:00:00"}