{"id":"https://openalex.org/W3133612934","doi":"https://doi.org/10.3389/fneur.2021.640719","title":"Optical Coherence Tomography Angiography for the Evaluation of Retinal Vasculature in Fabry Disease: Our Experience and Review of Current Knowledge","display_name":"Optical Coherence Tomography Angiography for the Evaluation of Retinal Vasculature in Fabry Disease: Our Experience and Review of Current Knowledge","publication_year":2021,"publication_date":"2021-03-09","ids":{"openalex":"https://openalex.org/W3133612934","doi":"https://doi.org/10.3389/fneur.2021.640719","mag":"3133612934","pmid":"https://pubmed.ncbi.nlm.nih.gov/33767663","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7985262"},"language":"en","primary_location":{"id":"doi:10.3389/fneur.2021.640719","doi":"https://doi.org/10.3389/fneur.2021.640719","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2021.640719","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2021.640719/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fneur.2021.640719/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055262547","display_name":"Daniela Bacherini","orcid":"https://orcid.org/0000-0001-7578-7563","observed_orcids":["https://orcid.org/0000-0001-7578-7563"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daniela Bacherini","raw_affiliation_strings":["Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044516573","display_name":"Giulio Vicini","orcid":"https://orcid.org/0000-0001-7646-7422","observed_orcids":["https://orcid.org/0000-0001-7646-7422"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giulio Vicini","raw_affiliation_strings":["Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072575853","display_name":"Cristina Nicolosi","orcid":"https://orcid.org/0000-0002-7384-3717","observed_orcids":["https://orcid.org/0000-0002-7384-3717"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cristina Nicolosi","raw_affiliation_strings":["Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040806298","display_name":"Ilaria Tanini","orcid":"https://orcid.org/0000-0002-5565-5122","observed_orcids":["https://orcid.org/0000-0002-5565-5122"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ilaria Tanini","raw_affiliation_strings":["Cardiomyopathy Unit, Department of Cardiology, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiomyopathy Unit, Department of Cardiology, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058839908","display_name":"Chiara Lenzetti","orcid":"https://orcid.org/0000-0002-9954-0407","observed_orcids":["https://orcid.org/0000-0002-9954-0407"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Lenzetti","raw_affiliation_strings":["Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029414683","display_name":"Lucia Finocchio","orcid":"https://orcid.org/0000-0003-1986-045X","observed_orcids":["https://orcid.org/0000-0003-1986-045X"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lucia Finocchio","raw_affiliation_strings":["Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025751196","display_name":"Lino Calogero Cirami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Lino Calogero Cirami","raw_affiliation_strings":["Nephrology Dialysis Transplant Unit, Medical Geriatric Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology Dialysis Transplant Unit, Medical Geriatric Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006184449","display_name":"Egrina Dervishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Egrina Dervishi","raw_affiliation_strings":["Nephrology Dialysis Transplant Unit, Medical Geriatric Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nephrology Dialysis Transplant Unit, Medical Geriatric Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075007010","display_name":"Stanislao Rizzo","orcid":"https://orcid.org/0000-0001-6302-063X","observed_orcids":["https://orcid.org/0000-0001-6302-063X"]},"institutions":[{"id":"https://openalex.org/I103320735","display_name":"Universit\u00e0 Cattolica del Sacro Cuore","ror":"https://ror.org/03h7r5v07","country_code":"IT","type":"education","lineage":["https://openalex.org/I103320735"]},{"id":"https://openalex.org/I2802557943","display_name":"Agostino Gemelli University Polyclinic","ror":"https://ror.org/00rg70c39","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I2802557943"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stanislao Rizzo","raw_affiliation_strings":["Consiglio Nazionale della Ricerca (CNR), Pisa, Italy","Ophthalmology Unit, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Consiglio Nazionale della Ricerca (CNR), Pisa, Italy","institution_ids":["https://openalex.org/I4210155236"]},{"raw_affiliation_string":"Ophthalmology Unit, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli, Rome, Italy","institution_ids":["https://openalex.org/I103320735","https://openalex.org/I2802557943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015954067","display_name":"Gianni Virgili","orcid":"https://orcid.org/0000-0002-9960-2989","observed_orcids":["https://orcid.org/0000-0002-9960-2989"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianni Virgili","raw_affiliation_strings":["Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy","Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy","institution_ids":["https://openalex.org/I45084792"]},{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037612904","display_name":"Fabrizio Giansanti","orcid":"https://orcid.org/0000-0002-4107-2807","observed_orcids":["https://orcid.org/0000-0002-4107-2807"]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]},{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabrizio Giansanti","raw_affiliation_strings":["Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy","Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosciences, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy","institution_ids":["https://openalex.org/I45084792"]},{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083739103","display_name":"Andrea Sodi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115393","display_name":"Azienda Ospedaliero-Universitaria Careggi","ror":"https://ror.org/02crev113","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210115393"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Sodi","raw_affiliation_strings":["Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Eye Clinic, Neuromuscular and Sense Organs Department, Careggi University Hospital, Florence, Italy","institution_ids":["https://openalex.org/I4210115393"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5044516573"],"corresponding_institution_ids":["https://openalex.org/I4210115393"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":1.0702,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.72914569,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"12","issue":null,"first_page":"640719","last_page":"640719"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10945","display_name":"Lysosomal Storage Disorders Research","score":0.6312999725341797,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10945","display_name":"Lysosomal Storage Disorders Research","score":0.6312999725341797,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.17810000479221344,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.0737999975681305,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fabry-disease","display_name":"Fabry disease","score":0.9869999885559082},{"id":"https://openalex.org/keywords/optical-coherence-tomography-angiography","display_name":"optical coherence tomography angiography","score":0.9359999895095825},{"id":"https://openalex.org/keywords/retinal-microvasculature","display_name":"retinal microvasculature","score":0.9580000042915344},{"id":"https://openalex.org/keywords/retinal-vessel-density","display_name":"retinal vessel density","score":0.8889999985694885},{"id":"https://openalex.org/keywords/retinal-blood-flow","display_name":"retinal blood flow","score":0.7689999938011169},{"id":"https://openalex.org/keywords/superficial-capillary-plexus","display_name":"superficial capillary plexus","score":0.9599999785423279},{"id":"https://openalex.org/keywords/deep-capillary-plexus","display_name":"deep capillary plexus","score":1.0},{"id":"https://openalex.org/keywords/foveal-avascular-zone","display_name":"foveal avascular zone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/macula","display_name":"macula","score":0.6449999809265137},{"id":"https://openalex.org/keywords/retinal-microangiopathy","display_name":"retinal microangiopathy","score":0.5929999947547913},{"id":"https://openalex.org/keywords/disease-severity-correlation","display_name":"disease severity correlation","score":0.37400001287460327},{"id":"https://openalex.org/keywords/treatment-response-monitoring","display_name":"treatment response monitoring","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C2985858981","wikidata":"https://www.wikidata.org/wiki/Q60760969","display_name":"Optical coherence tomography angiography","level":3,"score":0.7991117238998413},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7661826610565186},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6525826454162598},{"id":"https://openalex.org/C2777655287","wikidata":"https://www.wikidata.org/wiki/Q28455839","display_name":"Foveal avascular zone","level":4,"score":0.5822098851203918},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.5355043411254883},{"id":"https://openalex.org/C2779988585","wikidata":"https://www.wikidata.org/wiki/Q7204920","display_name":"Plexus","level":2,"score":0.5348016023635864},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.5262212753295898},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.4822879135608673},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.45647767186164856},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3205944299697876},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.23832419514656067},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.19426807761192322}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/fneur.2021.640719","doi":"https://doi.org/10.3389/fneur.2021.640719","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2021.640719","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2021.640719/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7985262","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7985262","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Neurol","raw_type":"Text"},{"id":"pmid:33767663","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33767663","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in neurology","raw_type":"Journal Article"},{"id":"pmh:oai:flore.unifi.it:2158/1256404","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2158/1256404","pdf_url":"https://flore.unifi.it/bitstream/2158/1256404/1/fneur-12-640719.pdf","source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:072f7d2a0e194e0889d477808cd10560","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/072f7d2a0e194e0889d477808cd10560","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Neurology, Vol 12 (2021)","raw_type":"article"},{"id":"pmh:oai:publicatt.unicatt.it:10807/247614","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10807/247614","pdf_url":null,"source":{"id":"https://openalex.org/S4306400564","display_name":"PubliCatt (Universit\u00e0 Cattolica del Sacro Cuore)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3389/fneur.2021.640719","doi":"https://doi.org/10.3389/fneur.2021.640719","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fneur.2021.640719","pdf_url":"https://www.frontiersin.org/articles/10.3389/fneur.2021.640719/pdf","source":{"id":"https://openalex.org/S96975567","display_name":"Frontiers in Neurology","issn_l":"1664-2295","issn":["1664-2295"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Neurology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3133612934.pdf","grobid_xml":"https://content.openalex.org/works/W3133612934.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W38077790","https://openalex.org/W1587564125","https://openalex.org/W1931689468","https://openalex.org/W1970421495","https://openalex.org/W1983553272","https://openalex.org/W1987120501","https://openalex.org/W2001951305","https://openalex.org/W2006259690","https://openalex.org/W2026893678","https://openalex.org/W2040886800","https://openalex.org/W2048384915","https://openalex.org/W2055917627","https://openalex.org/W2062214448","https://openalex.org/W2080115121","https://openalex.org/W2085329278","https://openalex.org/W2088813643","https://openalex.org/W2091098209","https://openalex.org/W2091843493","https://openalex.org/W2093722439","https://openalex.org/W2094355363","https://openalex.org/W2101144227","https://openalex.org/W2101425200","https://openalex.org/W2101510401","https://openalex.org/W2142787387","https://openalex.org/W2484850489","https://openalex.org/W2806087996","https://openalex.org/W2886272716","https://openalex.org/W2907026176","https://openalex.org/W2908587733","https://openalex.org/W2936873852","https://openalex.org/W2939066048","https://openalex.org/W2943963479","https://openalex.org/W2954923205","https://openalex.org/W2977185698","https://openalex.org/W2987778357","https://openalex.org/W2997484292","https://openalex.org/W3002704207","https://openalex.org/W3016771387","https://openalex.org/W3017078970","https://openalex.org/W3039290057","https://openalex.org/W3089990288","https://openalex.org/W3107886943","https://openalex.org/W3111173698"],"related_works":["https://openalex.org/W3119797173","https://openalex.org/W3039290057","https://openalex.org/W2939066048","https://openalex.org/W3107886943","https://openalex.org/W3111173698","https://openalex.org/W4385597254","https://openalex.org/W4360851408","https://openalex.org/W4387440915","https://openalex.org/W4385346662","https://openalex.org/W2954923205"],"abstract_inverted_index":{"Purpose:":[0],"Optical":[1],"coherence":[2],"tomography":[3],"angiography":[4],"(OCTA)":[5],"is":[6,154],"a":[7,301,307],"non-invasive":[8,303],"and":[9,33,43,69,90,99,109,112,120,134,136,140,240,265,269,280,288],"objective":[10,332],"tool":[11,333],"for":[12],"the":[13,16,34,45,87,103,114,126,147,167,185,202,205,213,277,317,326,357,361],"evaluation":[14,309],"of":[15,48,101,113,150,310,328,343,360],"retinal":[17,28,311,336],"microvascular":[18],"changes":[19,26],"in":[20,27,30,82,93,152,166,184,201,211,258,292,314,321,339,345],"Fabry":[21],"disease":[22],"(FD).":[23],"We":[24,85,123],"investigated":[25],"vasculature":[29],"FD":[31,52,153,158,293,346],"patients,":[32],"possible":[35],"correlation":[36,137],"with":[37,66],"systemic":[38,139,281],"parameters,":[39],"by":[40,351],"using":[41],"OCTA,":[42],"reviewed":[44],"current":[46,148],"status":[47],"literature.":[49,322],"Methods:":[50],"Thirteen":[51],"patients":[53,159],"(eight":[54],"females,":[55],"five":[56],"males,":[57],"mean":[58],"age":[59],"49.85":[60],"\u00b1":[61,171,176,189,194,218,223,230,235,243,248],"14.7":[62],"years)":[63],"were":[64,80,254,274],"compared":[65],"13":[67],"age-":[68],"sex-matched":[70],"healthy":[71],"controls.":[72],"OCTA":[73,141,151,278,296,329,344],"3":[74,76],"\u00d7":[75],"mm":[77],"macular":[78,95],"scans":[79],"performed":[81],"all":[83,212],"subjects.":[84],"evaluated":[86,125],"vessel":[88,91,259],"density":[89],"perfusion":[92,260],"distinct":[94],"areas":[96],"(whole,":[97],"inner,":[98],"outer)":[100],"both":[102],"superficial":[104],"capillary":[105,116],"plexus":[106,117],"(SCP":[107],"VD":[108,119,164,207],"SCP":[110,163,263],"VP)":[111],"deep":[115],"(DCP":[118],"DCP":[121,206,266],"VP).":[122],"also":[124],"foveal":[127],"avascular":[128],"zone":[129],"(FAZ)":[130],"metrics":[131],"(area,":[132],"perimeter,":[133],"circularity),":[135],"between":[138,276],"parameters.":[142],"A":[143],"literature":[144],"review":[145],"on":[146],"understanding":[149],"then":[155],"presented.":[156],"Results:":[157],"showed":[160],"significantly":[161,209],"lower":[162,210],"values":[165],"whole":[168,216],"area":[169,187],"(17.37":[170],"2.08":[172],"mm\u22121":[173,191,220,232,245],"vs.":[174,192,221,233,246],"18.54":[175],"1.21":[177],"mm\u22121;":[178,196,225,237,250],"p-value":[179,197,226,238,251],"0.022),":[180],"as":[181,183,300,330],"well":[182],"outer":[186,228],"(17.46":[188],"2.10":[190],"19.08":[193],"1.14":[195],"0.002),":[198],"but":[199],"not":[200],"inner.":[203],"Even":[204],"was":[208],"imaged":[214],"areas:":[215],"(17.75":[217],"3.93":[219],"19.71":[222],"1.20":[224,236],"0.024),":[227],"(18.25":[229],"4.17":[231,244],"20.33":[234],"0.023),":[239],"inner":[241],"(19.54":[242],"21.96":[247],"1.55":[249],"0.011).":[252],"There":[253],"no":[255],"significant":[256,272],"differences":[257],"parameters":[261,279,282],"(both":[262],"VP":[264,267],"ones)":[268],"FAZ.":[270],"No":[271],"correlations":[273],"found":[275],"(maximal":[283],"left":[284],"ventricular":[285],"wall":[286],"thickness":[287],"glomerular":[289],"filtration":[290],"rate)":[291],"patients.":[294],"Conclusions:":[295],"can":[297],"be":[298,349],"considered":[299],"promising":[302],"tool,":[304],"which":[305],"enables":[306],"quantitative":[308],"vascular":[312,337],"involvement":[313],"FD,":[315],"despite":[316],"varying":[318],"data":[319],"reported":[320],"Our":[323],"results":[324],"support":[325],"use":[327],"an":[331],"to":[334,348],"evaluate":[335],"abnormalities":[338],"FD.":[340],"The":[341],"utility":[342],"needs":[347],"validated":[350],"longitudinal":[352],"studies":[353],"taking":[354],"into":[355],"account":[356],"overall":[358],"progression":[359],"disease.":[362]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2021-03-15T00:00:00"}