{"id":"https://openalex.org/W3133609929","doi":"https://doi.org/10.5543/tkda.2021.72273","title":"Impact of transcatheter aortic valve implantation in symptomatic patients with very severe aortic stenosis","display_name":"Impact of transcatheter aortic valve implantation in symptomatic patients with very severe aortic stenosis","publication_year":2021,"publication_date":"2021-03-04","ids":{"openalex":"https://openalex.org/W3133609929","doi":"https://doi.org/10.5543/tkda.2021.72273","mag":"3133609929","pmid":"https://pubmed.ncbi.nlm.nih.gov/33709915"},"language":"en","primary_location":{"id":"doi:10.5543/tkda.2021.72273","doi":"https://doi.org/10.5543/tkda.2021.72273","is_oa":true,"landing_page_url":"https://doi.org/10.5543/tkda.2021.72273","pdf_url":null,"source":{"id":"https://openalex.org/S4210222713","display_name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","issn_l":"1308-4488","issn":["1308-4488","1016-5169"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4310318429","host_organization_name":"KARE Publishing","host_organization_lineage":["https://openalex.org/P4310318429"],"host_organization_lineage_names":["KARE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.5543/tkda.2021.72273","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003859463","display_name":"Bilge Duran Karaduman","orcid":"https://orcid.org/0000-0003-0129-7232","observed_orcids":["https://orcid.org/0000-0003-0129-7232"]},"institutions":[{"id":"https://openalex.org/I45542416","display_name":"Atilim University","ror":"https://ror.org/04pd3v454","country_code":"TR","type":"education","lineage":["https://openalex.org/I45542416"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Bilge Duran Karaduman","raw_affiliation_strings":["Department of Cardiology, At\u0131l\u0131m University School of Medicine, Medicana International Ankara Hospital, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, At\u0131l\u0131m University School of Medicine, Medicana International Ankara Hospital, Ankara, Turkey","institution_ids":["https://openalex.org/I45542416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055944226","display_name":"H\u00fcseyin Ayhan","orcid":"https://orcid.org/0000-0002-9991-7307","observed_orcids":["https://orcid.org/0000-0002-9991-7307"]},"institutions":[{"id":"https://openalex.org/I45542416","display_name":"Atilim University","ror":"https://ror.org/04pd3v454","country_code":"TR","type":"education","lineage":["https://openalex.org/I45542416"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Huseyin Ayhan","raw_affiliation_strings":["Department of Cardiology, At\u0131l\u0131m University School of Medicine, Medicana International Ankara Hospital, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, At\u0131l\u0131m University School of Medicine, Medicana International Ankara Hospital, Ankara, Turkey","institution_ids":["https://openalex.org/I45542416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041385043","display_name":"Telat Kele\u015f","orcid":"https://orcid.org/0000-0001-5372-8351","observed_orcids":["https://orcid.org/0000-0001-5372-8351"]},"institutions":[{"id":"https://openalex.org/I4210150808","display_name":"Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University","ror":"https://ror.org/05ryemn72","country_code":"TR","type":"education","lineage":["https://openalex.org/I4210150808"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Telat Keles","raw_affiliation_strings":["Department of Cardiology, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University School of Medicine, Ankara City Hospital, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Ankara Y\u0131ld\u0131r\u0131m Beyaz\u0131t University School of Medicine, Ankara City Hospital, Ankara, Turkey","institution_ids":["https://openalex.org/I4210150808"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057566576","display_name":"Engin Bozkurt","orcid":"https://orcid.org/0000-0002-9783-7274","observed_orcids":["https://orcid.org/0000-0002-9783-7274"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Engin Bozkurt","raw_affiliation_strings":["Department of Cardiology, Medicana International Ankara Hospital, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Medicana International Ankara Hospital, Ankara, Turkey","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3349,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.57973337,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"49","issue":"2","first_page":"97","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcatheter-aortic-valve-replacement","display_name":"transcatheter aortic valve implantation","score":1.0},{"id":"https://openalex.org/keywords/symptomatic-aortic-stenosis","display_name":"symptomatic aortic stenosis","score":0.9350000023841858},{"id":"https://openalex.org/keywords/high-gradient-aortic-stenosis","display_name":"high-gradient aortic stenosis","score":0.984000027179718},{"id":"https://openalex.org/keywords/in-hospital-mortality","display_name":"in-hospital mortality","score":0.859000027179718},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.5270000100135803},{"id":"https://openalex.org/keywords/edwards-sapien-3","display_name":"Edwards SAPIEN 3","score":0.7680000066757202},{"id":"https://openalex.org/keywords/predilatation","display_name":"predilatation","score":0.7710000276565552},{"id":"https://openalex.org/keywords/left-ventricular-hypertrophy","display_name":"left ventricular hypertrophy","score":0.6399999856948853},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8292568922042847},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.6445280313491821},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.6049097776412964},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5876186490058899},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.582795262336731},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.5809794664382935},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.5661438703536987},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5365991592407227},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4817478656768799},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.4816376268863678},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.4375233054161072},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.4147733747959137},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.27028852701187134}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D001026","descriptor_name":"Coronary Artery Bypass","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005240","descriptor_name":"Feasibility Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D065467","descriptor_name":"Transcatheter Aortic Valve Replacement","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D065467","descriptor_name":"Transcatheter Aortic Valve Replacement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.5543/tkda.2021.72273","doi":"https://doi.org/10.5543/tkda.2021.72273","is_oa":true,"landing_page_url":"https://doi.org/10.5543/tkda.2021.72273","pdf_url":null,"source":{"id":"https://openalex.org/S4210222713","display_name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","issn_l":"1308-4488","issn":["1308-4488","1016-5169"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4310318429","host_organization_name":"KARE Publishing","host_organization_lineage":["https://openalex.org/P4310318429"],"host_organization_lineage_names":["KARE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","raw_type":"journal-article"},{"id":"pmid:33709915","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33709915","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","raw_type":"Journal Article"},{"id":"pmh:c832abf0-8f1b-4ad3-b39e-1e24a46d57ee","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/c832abf0-8f1b-4ad3-b39e-1e24a46d57ee/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:9cc7e6e7afc8459ca7158b22bc05dcd8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9cc7e6e7afc8459ca7158b22bc05dcd8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"T\u00fcrk Kardiyoloji Derne\u011fi Ar\u015fivi, Vol 49, Iss 2, Pp 97-107 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.5543/tkda.2021.72273","doi":"https://doi.org/10.5543/tkda.2021.72273","is_oa":true,"landing_page_url":"https://doi.org/10.5543/tkda.2021.72273","pdf_url":null,"source":{"id":"https://openalex.org/S4210222713","display_name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","issn_l":"1308-4488","issn":["1308-4488","1016-5169"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3","tr-dizin"],"host_organization":"https://openalex.org/P4310318429","host_organization_name":"KARE Publishing","host_organization_lineage":["https://openalex.org/P4310318429"],"host_organization_lineage_names":["KARE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4385516463","https://openalex.org/W4386064848","https://openalex.org/W2803045958","https://openalex.org/W4410940765","https://openalex.org/W4393948402","https://openalex.org/W2904035445","https://openalex.org/W2001403340","https://openalex.org/W4367834070","https://openalex.org/W4297173676","https://openalex.org/W2139151408"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Aortic":[1],"stenosis":[2],"(AS)":[3],"is":[4,29,45,67],"a":[5,122,129,222],"progressive":[6],"disease,":[7],"and":[8,20,72,109,128,171,178,198,257,265],"valve":[9,27,55,288],"replacement-the":[10],"only":[11],"treatment":[12],"option-should":[13],"be":[14,255],"performed":[15],"after":[16],"it":[17,248],"becomes":[18],"symptomatic":[19,77,89,260],"before":[21],"irreversible":[22],"myocardial":[23,169],"damages":[24],"develop.":[25],"Surgical":[26],"replacement":[28],"recommended":[30],"in":[31,58,64,76,94,153,185,195,229,259,278],"patients":[32,59,78,87,105,116,279],"with":[33,60,79,88,124,131,156,188,202,207,234,262,280],"very":[34],"severe":[35],"AS":[36,133],"(VSAS),":[37],"even":[38],"if":[39],"they":[40],"are":[41,273],"asymptomatic.":[42],"However,":[43],"there":[44],"no":[46,192],"detailed":[47],"study":[48,66],"on":[49,158,236],"the":[50,70,104,154,159,186,214,226,232,237],"effect":[51],"of":[52,74,84,103,111,163,231],"transcatheter":[53],"aortic":[54,287],"implantation":[56],"(TAVI)":[57],"VSAS.":[61,80,189],"Our":[62],"aim":[63],"this":[65,246],"to":[68,213,275],"show":[69],"feasibility":[71],"safety":[73],"TAVI":[75,93,253,277],"METHODS:":[81],"A":[82],"total":[83],"505":[85],"consecutive":[86],"AD":[90],"who":[91],"underwent":[92],"our":[95],"center":[96],"were":[97,113,117,150,174,182],"retrospectively":[98],"studied.":[99],"The":[100,115],"mean":[101],"age":[102],"was":[106,191,221],"77.8\u00b17.6":[107],"years,":[108],"56.4%":[110],"them":[112],"women.":[114],"divided":[118],"into":[119],"2":[120,227],"groups:":[121],"group":[123,130,155,187,206,233],"VSAS":[125,235,282],"(n=134":[126],"patients)":[127],"high-gradient":[132],"(HGAS)":[134],"(n=371":[135],"patients).":[136],"RESULTS:":[137],"Female":[138],"sex,":[139],"left":[140,145,148],"ventricular":[141],"ejection":[142],"fraction,":[143],"small":[144],"ventricle,":[146],"hypertrophic":[147],"ventricle":[149],"more":[151],"common":[152],"VSAS;":[157],"other":[160],"hand,":[161],"histories":[162],"coronary":[164],"artery":[165],"disease":[166],"bypass":[167],"surgery,":[168],"infarction,":[170],"atrial":[172],"fibrillation":[173],"less":[175,183],"frequent.":[176],"Predilatation":[177],"Edwards":[179],"SAPIEN":[180],"3":[181],"used":[184],"There":[190,220],"statistical":[193],"difference":[194,224],"major":[196],"complications":[197,264],"in-hospital":[199],"mortality":[200],"(group":[201],"VSAS:":[203],"5":[204],"patients,":[205],"HGAS:":[208],"16":[209],"patients;":[210],"p=0.769)":[211],"according":[212],"Valve":[215],"Academic":[216],"Research":[217],"Consortium-2":[218],"criteria.":[219],"significant":[223],"between":[225],"groups":[228],"favor":[230],"Cox":[238],"regression":[239],"model":[240],"survival":[241,267],"curve":[242],"(p<0.001).":[243],"CONCLUSION:":[244],"In":[245],"study,":[247],"has":[249],"been":[250],"shown":[251],"that":[252],"can":[254],"feasible":[256],"safe":[258],"VSAS,":[261],"acceptable":[263],"higher":[266],"rates.":[268],"Currently,":[269],"further":[270],"randomized":[271],"studies":[272],"required":[274],"perform":[276],"asymptomatic":[281],"currently":[283],"indicated":[284],"for":[285],"surgical":[286],"replacement.":[289]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-03-15T00:00:00"}