{"id":"https://openalex.org/W31335562","doi":null,"title":"Arginine vasopressin as a central neurotransmitter.","display_name":"Arginine vasopressin as a central neurotransmitter.","publication_year":1986,"publication_date":"1986-08-01","ids":{"openalex":"https://openalex.org/W31335562","mag":"31335562","pmid":"https://pubmed.ncbi.nlm.nih.gov/2874053"},"language":"en","primary_location":{"id":"pmid:2874053","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2874053","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Federation proceedings","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060808228","display_name":"Colleen L. Riphagen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C L Riphagen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5019840028","display_name":"Quentin J. Pittman","orcid":"https://orcid.org/0000-0003-0984-7665","observed_orcids":["https://orcid.org/0000-0003-0984-7665"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Q J Pittman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.0404,"has_fulltext":false,"cited_by_count":47,"citation_normalized_percentile":{"value":0.95063905,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"45","issue":"9","first_page":"2318","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.6875,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.6875,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.28049999475479126,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vasopressin","display_name":"vasopressin","score":1.0},{"id":"https://openalex.org/keywords/central-neurotransmitters","display_name":"central neurotransmitters","score":0.7609999775886536},{"id":"https://openalex.org/keywords/hypothalamic-nuclei","display_name":"hypothalamic nuclei","score":0.7279999852180481},{"id":"https://openalex.org/keywords/neuroendocrine-regulation","display_name":"neuroendocrine regulation","score":0.47699999809265137},{"id":"https://openalex.org/keywords/cardiovascular-regulation","display_name":"cardiovascular regulation","score":0.6819999814033508},{"id":"https://openalex.org/keywords/renal-regulation","display_name":"renal regulation","score":0.7089999914169312},{"id":"https://openalex.org/keywords/thermoregulation","display_name":"thermoregulation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/homeostasis","display_name":"homeostasis","score":0.8820000290870667},{"id":"https://openalex.org/keywords/autonomic-responses","display_name":"autonomic responses","score":0.5360000133514404}],"concepts":[{"id":"https://openalex.org/C2776370428","wikidata":"https://www.wikidata.org/wiki/Q21124841","display_name":"Vasopressin","level":2,"score":0.9315876960754395},{"id":"https://openalex.org/C2776219046","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter","level":3,"score":0.7159000039100647},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.685571551322937},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6676079034805298},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6439962387084961},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.6150415539741516},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5049787163734436},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4823702871799469},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.47712206840515137},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.4551510810852051},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4458497166633606},{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.4340433180332184},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.42924267053604126},{"id":"https://openalex.org/C90474776","wikidata":"https://www.wikidata.org/wiki/Q24784390","display_name":"Vasopressin receptor","level":4,"score":0.41438916325569153},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2207431197166443},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.12811201810836792},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.07754892110824585},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.05609658360481262},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001127","descriptor_name":"Arginine Vasopressin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001341","descriptor_name":"Autonomic Nervous System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001833","descriptor_name":"Body Temperature Regulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002320","descriptor_name":"Cardiovascular Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D010286","descriptor_name":"Paraventricular Hypothalamic Nucleus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010286","descriptor_name":"Paraventricular Hypothalamic Nucleus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011945","descriptor_name":"Receptors, Angiotensin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013495","descriptor_name":"Supraoptic Nucleus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D017483","descriptor_name":"Receptors, Vasopressin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018377","descriptor_name":"Neurotransmitter Agents","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:2874053","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2874053","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Federation proceedings","raw_type":"Journal Article"},{"id":"mag:31335562","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2874053","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1830758076","https://openalex.org/W1975190957","https://openalex.org/W2021356296","https://openalex.org/W2056488712","https://openalex.org/W2089125052","https://openalex.org/W2135415803","https://openalex.org/W2312354038","https://openalex.org/W2417817914","https://openalex.org/W2764203772"],"related_works":["https://openalex.org/W1001688202","https://openalex.org/W2418546976","https://openalex.org/W144818384","https://openalex.org/W2146536715","https://openalex.org/W1484414193","https://openalex.org/W2297170652","https://openalex.org/W1974724853","https://openalex.org/W2129035961","https://openalex.org/W2007115091","https://openalex.org/W1978450007"],"abstract_inverted_index":{"Anatomical":[0],"and":[1,85,120,130],"electrophysiological":[2],"studies":[3],"have":[4,77],"revealed":[5],"a":[6,109],"widespread":[7],"innervation":[8],"of":[9,33,46,58,74,87,116],"the":[10,75,99,113,117],"brain":[11,76],"by":[12],"arginine":[13],"vasopressin":[14],"(AVP)-containing":[15],"fibers.":[16],"There":[17],"is":[18],"evidence":[19],"that":[20,36],"these":[21,54,92],"central":[22,114],"AVP":[23,38,51,60,83,88,104,123],"pathways":[24],"may":[25,124],"be":[26,62],"activated":[27],"simultaneously":[28],"with":[29],"endocrine":[30,131],"pathways.":[31],"Stimulation":[32],"hypothalamic":[34,70],"nuclei":[35],"contain":[37,82],"cell":[39],"bodies":[40],"causes":[41],"changes":[42],"in":[43,48,53,64,91,112],"electrical":[44],"activity":[45,96],"neurons":[47],"areas":[49,93],"receiving":[50],"projections;":[52],"same":[55],"regions,":[56],"release":[57],"immunoreactive":[59],"can":[61],"detected":[63],"response":[65],"to":[66,81,89,101,106,127,133],"appropriate":[67],"stimuli":[68],"or":[69,97],"stimulation.":[71],"These":[72],"parts":[73],"also":[78],"been":[79],"shown":[80],"receptors,":[84],"application":[86],"cells":[90],"alters":[94],"spontaneous":[95],"modifies":[98],"responses":[100,132],"other":[102],"transmitters.":[103],"appears":[105],"act":[107,125],"as":[108],"neurotransmitter":[110],"involved":[111],"control":[115],"cardiovascular,":[118],"renal,":[119],"thermoregulatory":[121],"systems.":[122],"centrally":[126],"coordinate":[128],"autonomic":[129],"homeostatic":[134],"perturbations.":[135]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}