{"id":"https://openalex.org/W3133553352","doi":"https://doi.org/10.1016/j.ijbiomac.2021.03.008","title":"Evaluation of human umbilical vein endothelial cells growth onto heparin-modified electrospun vascular grafts","display_name":"Evaluation of human umbilical vein endothelial cells growth onto heparin-modified electrospun vascular grafts","publication_year":2021,"publication_date":"2021-03-03","ids":{"openalex":"https://openalex.org/W3133553352","doi":"https://doi.org/10.1016/j.ijbiomac.2021.03.008","mag":"3133553352","pmid":"https://pubmed.ncbi.nlm.nih.gov/33675835"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijbiomac.2021.03.008","doi":"https://doi.org/10.1016/j.ijbiomac.2021.03.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2021.03.008","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11336/182631","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031902197","display_name":"Pablo C. Caracciolo","orcid":"https://orcid.org/0000-0002-8432-797X","observed_orcids":["https://orcid.org/0000-0002-8432-797X"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I189075073","display_name":"National University of Mar del Plata","ror":"https://ror.org/055eqsb67","country_code":"AR","type":"education","lineage":["https://openalex.org/I189075073"]},{"id":"https://openalex.org/I4210129969","display_name":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales","ror":"https://ror.org/034s8ev31","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210129969","https://openalex.org/I4210163267","https://openalex.org/I4387155568"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Pablo C. Caracciolo","raw_affiliation_strings":["Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina. Electronic address: pcaracciolo@fi.mdp.edu.ar","Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina. Electronic address: pcaracciolo@fi.mdp.edu.ar","institution_ids":["https://openalex.org/I189075073","https://openalex.org/I4210129969"]},{"raw_affiliation_string":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I189075073","https://openalex.org/I4210129969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000321249","display_name":"Patricia D\u00edaz\u2010Rodr\u00edguez","orcid":"https://orcid.org/0000-0002-7576-2013","observed_orcids":["https://orcid.org/0000-0002-7576-2013"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]},{"id":"https://openalex.org/I4210148771","display_name":"Instituto de Investigaci\u00f3n Sanitaria de Santiago","ror":"https://ror.org/05n7xcf53","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210148771"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Patricia Diaz-Rodriguez","raw_affiliation_strings":["Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica, I+D Farma (GI-1645), Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica, I+D Farma (GI-1645), Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239","https://openalex.org/I4210148771"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035694316","display_name":"In\u00e9s Ardao","orcid":"https://orcid.org/0000-0002-1201-4165","observed_orcids":["https://orcid.org/0000-0002-1201-4165"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]},{"id":"https://openalex.org/I4210111807","display_name":"Center for Research in Molecular Medicine and Chronic Diseases","ror":"https://ror.org/0280bnq76","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210111807"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"In\u00e9s Ardao","raw_affiliation_strings":["BioFarma Research group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioFarma Research group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239","https://openalex.org/I4210111807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101604623","display_name":"David Moreira","orcid":"https://orcid.org/0000-0002-1171-0169","observed_orcids":["https://orcid.org/0000-0002-1171-0169"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]},{"id":"https://openalex.org/I4210111807","display_name":"Center for Research in Molecular Medicine and Chronic Diseases","ror":"https://ror.org/0280bnq76","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210111807"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"David Moreira","raw_affiliation_strings":["BioFarma Research group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioFarma Research group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239","https://openalex.org/I4210111807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077848033","display_name":"Florencia Montini Ballar\u00edn","orcid":"https://orcid.org/0000-0003-2357-4106","observed_orcids":["https://orcid.org/0000-0003-2357-4106"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I189075073","display_name":"National University of Mar del Plata","ror":"https://ror.org/055eqsb67","country_code":"AR","type":"education","lineage":["https://openalex.org/I189075073"]},{"id":"https://openalex.org/I4210129969","display_name":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales","ror":"https://ror.org/034s8ev31","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210129969","https://openalex.org/I4210163267","https://openalex.org/I4387155568"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Florencia Montini-Ballarin","raw_affiliation_strings":["Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I189075073","https://openalex.org/I4210129969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027438747","display_name":"Gustavo A. Abraham","orcid":"https://orcid.org/0000-0001-7094-1031","observed_orcids":["https://orcid.org/0000-0001-7094-1031"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I189075073","display_name":"National University of Mar del Plata","ror":"https://ror.org/055eqsb67","country_code":"AR","type":"education","lineage":["https://openalex.org/I189075073"]},{"id":"https://openalex.org/I4210129969","display_name":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales","ror":"https://ror.org/034s8ev31","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4210129969","https://openalex.org/I4210163267","https://openalex.org/I4387155568"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Gustavo A. Abraham","raw_affiliation_strings":["Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Instituto de Investigaciones en Ciencia y Tecnolog\u00eda de Materiales, INTEMA (UNMdP-CONICET), Av. Crist\u00f3bal Col\u00f3n 10850, B7606WV Mar del Plata, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I189075073","https://openalex.org/I4210129969"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023016712","display_name":"\u00c1ngel Concheiro","orcid":"https://orcid.org/0000-0003-0507-049X","observed_orcids":["https://orcid.org/0000-0003-0507-049X"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]},{"id":"https://openalex.org/I4210148771","display_name":"Instituto de Investigaci\u00f3n Sanitaria de Santiago","ror":"https://ror.org/05n7xcf53","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210148771"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Angel Concheiro","raw_affiliation_strings":["Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica, I+D Farma (GI-1645), Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica, I+D Farma (GI-1645), Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239","https://openalex.org/I4210148771"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011667293","display_name":"Carmen Alvarez\u2010Lorenzo","orcid":"https://orcid.org/0000-0002-8546-7085","observed_orcids":["https://orcid.org/0000-0002-8546-7085"]},"institutions":[{"id":"https://openalex.org/I200284239","display_name":"Universidade de Santiago de Compostela","ror":"https://ror.org/030eybx10","country_code":"ES","type":"education","lineage":["https://openalex.org/I200284239"]},{"id":"https://openalex.org/I4210148771","display_name":"Instituto de Investigaci\u00f3n Sanitaria de Santiago","ror":"https://ror.org/05n7xcf53","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210148771"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Carmen Alvarez-Lorenzo","raw_affiliation_strings":["Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica, I+D Farma (GI-1645), Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Farmacolog\u00eda, Farmacia y Tecnolog\u00eda Farmac\u00e9utica, I+D Farma (GI-1645), Facultad de Farmacia and Health Research Institute of Santiago de Compostela (IDIS), Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain","institution_ids":["https://openalex.org/I200284239","https://openalex.org/I4210148771"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5031902197"],"corresponding_institution_ids":["https://openalex.org/I151201029","https://openalex.org/I189075073","https://openalex.org/I4210129969"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":1.0122,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.67687103,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"179","issue":null,"first_page":"567","last_page":"575"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10661","display_name":"biodegradable polymer synthesis and properties","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/small-diameter-vascular-grafts","display_name":"small-diameter vascular grafts","score":0.9900000095367432},{"id":"https://openalex.org/keywords/human-umbilical-vein-endothelial-cells","display_name":"human umbilical vein endothelial cells","score":0.9440000057220459},{"id":"https://openalex.org/keywords/endothelialization","display_name":"endothelialization","score":0.8899999856948853},{"id":"https://openalex.org/keywords/poly-l-lactic-acid","display_name":"poly(L-lactic acid)","score":0.9139999747276306},{"id":"https://openalex.org/keywords/segmented-polyurethanes","display_name":"segmented polyurethanes","score":0.9169999957084656},{"id":"https://openalex.org/keywords/anticoagulant-coatings","display_name":"anticoagulant coatings","score":0.7360000014305115},{"id":"https://openalex.org/keywords/neointimal-hyperplasia","display_name":"intimal hyperplasia","score":0.7889999747276306},{"id":"https://openalex.org/keywords/restenosis","display_name":"restenosis","score":0.8489999771118164},{"id":"https://openalex.org/keywords/flow-perfusion-bioreactor","display_name":"flow perfusion bioreactor","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.8060265779495239},{"id":"https://openalex.org/C2777411675","wikidata":"https://www.wikidata.org/wiki/Q1232438","display_name":"Umbilical vein","level":3,"score":0.7547675967216492},{"id":"https://openalex.org/C2778095995","wikidata":"https://www.wikidata.org/wiki/Q17147174","display_name":"Neointimal hyperplasia","level":4,"score":0.6180276274681091},{"id":"https://openalex.org/C115537861","wikidata":"https://www.wikidata.org/wiki/Q7645993","display_name":"Surface modification","level":2,"score":0.5501081943511963},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5443148612976074},{"id":"https://openalex.org/C2779751240","wikidata":"https://www.wikidata.org/wiki/Q16909635","display_name":"Intimal hyperplasia","level":3,"score":0.5202706456184387},{"id":"https://openalex.org/C2778283817","wikidata":"https://www.wikidata.org/wiki/Q6590597","display_name":"Restenosis","level":3,"score":0.48914292454719543},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.46058908104896545},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44205427169799805},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3418414294719696},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23986974358558655},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.23012974858283997},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18672117590904236},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.14373499155044556},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.12260288000106812},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09952837228775024},{"id":"https://openalex.org/C2992686903","wikidata":"https://www.wikidata.org/wiki/Q208453","display_name":"Smooth muscle","level":2,"score":0.09387153387069702},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001705","descriptor_name":"Bioprosthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001807","descriptor_name":"Blood Vessel Prosthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006493","descriptor_name":"Heparin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011091","descriptor_name":"Polyesters","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011140","descriptor_name":"Polyurethanes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ijbiomac.2021.03.008","doi":"https://doi.org/10.1016/j.ijbiomac.2021.03.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2021.03.008","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},{"id":"pmid:33675835","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33675835","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of biological macromolecules","raw_type":"Journal Article"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/182631","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/182631","pdf_url":null,"source":{"id":"https://openalex.org/S4306402455","display_name":"CONICET Digital (CONICET)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210148385","host_organization_name":"Biomedicine Research Institute of Buenos Aires - CONICET - Partner Institute of the Max Planck Society","host_organization_lineage":["https://openalex.org/I4210148385"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ri.conicet.gov.ar:11336/182631","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/182631","pdf_url":null,"source":{"id":"https://openalex.org/S4306402455","display_name":"CONICET Digital (CONICET)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210148385","host_organization_name":"Biomedicine Research Institute of Buenos Aires - CONICET - Partner Institute of the Max Planck Society","host_organization_lineage":["https://openalex.org/I4210148385"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.9074000120162964,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1250599797","display_name":null,"funder_award_id":"[ED431C 2020/17]","funder_id":"https://openalex.org/F4320326655","funder_display_name":"Xunta de Galicia"},{"id":"https://openalex.org/G1496055848","display_name":null,"funder_award_id":"ED431C","funder_id":"https://openalex.org/F4320326655","funder_display_name":"Xunta de Galicia"},{"id":"https://openalex.org/G1514948572","display_name":null,"funder_award_id":"0245_IBEROS_1_E","funder_id":"https://openalex.org/F4320337753","funder_display_name":"Interreg"},{"id":"https://openalex.org/G2257750506","display_name":null,"funder_award_id":"PIP 153/2017","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"},{"id":"https://openalex.org/G2563636520","display_name":null,"funder_award_id":"ED431C 2018/21","funder_id":"https://openalex.org/F4320326655","funder_display_name":"Xunta de Galicia"},{"id":"https://openalex.org/G2774277990","display_name":null,"funder_award_id":"ED431C 2020/17","funder_id":"https://openalex.org/F4320335598","funder_display_name":"Agencia Estatal de Investigaci\u00f3n"},{"id":"https://openalex.org/G3013207569","display_name":null,"funder_award_id":"ED431C 2018","funder_id":"https://openalex.org/F4320326655","funder_display_name":"Xunta de Galicia"},{"id":"https://openalex.org/G3022609761","display_name":null,"funder_award_id":"SAF2017","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G3340828888","display_name":null,"funder_award_id":"0245_IBEROS_1_E","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G3366348290","display_name":null,"funder_award_id":"15/G479","funder_id":"https://openalex.org/F4320324137","funder_display_name":"Universidad Nacional de Mar del Plata"},{"id":"https://openalex.org/G3694284866","display_name":null,"funder_award_id":"ED431C","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G4593736749","display_name":null,"funder_award_id":"ED431C 2020/17","funder_id":"https://openalex.org/F4320335322","funder_display_name":"European Regional Development Fund"},{"id":"https://openalex.org/G5299004378","display_name":null,"funder_award_id":"SAF2017-83118-R","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G799088459","display_name":null,"funder_award_id":"0245_IBEROS_1_E","funder_id":"https://openalex.org/F4320326655","funder_display_name":"Xunta de Galicia"},{"id":"https://openalex.org/G8949478164","display_name":null,"funder_award_id":"UNMdP 15/G479","funder_id":"https://openalex.org/F4320321594","funder_display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas"}],"funders":[{"id":"https://openalex.org/F4320321594","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59"},{"id":"https://openalex.org/F4320321837","display_name":"Ministerio de Econom\u00eda y Competitividad","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320324137","display_name":"Universidad Nacional de Mar del Plata","ror":"https://ror.org/055eqsb67"},{"id":"https://openalex.org/F4320326262","display_name":"Ministerio de Asuntos Econ\u00f3micos y Transformaci\u00f3n Digital, Gobierno de Espa\u00f1a","ror":"https://ror.org/03sv46s19"},{"id":"https://openalex.org/F4320326655","display_name":"Xunta de Galicia","ror":"https://ror.org/0181xnw06"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320335598","display_name":"Agencia Estatal de Investigaci\u00f3n","ror":"https://ror.org/003x0zc53"},{"id":"https://openalex.org/F4320337753","display_name":"Interreg","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W72375187","https://openalex.org/W73025263","https://openalex.org/W302522192","https://openalex.org/W1510666142","https://openalex.org/W1526264206","https://openalex.org/W1893534297","https://openalex.org/W1947478030","https://openalex.org/W1961254684","https://openalex.org/W1964045646","https://openalex.org/W1965477306","https://openalex.org/W1966339848","https://openalex.org/W1968293867","https://openalex.org/W1969246401","https://openalex.org/W1971288132","https://openalex.org/W1975292287","https://openalex.org/W1976221882","https://openalex.org/W1980017356","https://openalex.org/W1987849092","https://openalex.org/W1997552417","https://openalex.org/W2003797941","https://openalex.org/W2011152593","https://openalex.org/W2011779540","https://openalex.org/W2023506111","https://openalex.org/W2024770520","https://openalex.org/W2027879497","https://openalex.org/W2040165312","https://openalex.org/W2049163785","https://openalex.org/W2050370340","https://openalex.org/W2052925470","https://openalex.org/W2053992333","https://openalex.org/W2060820658","https://openalex.org/W2065995478","https://openalex.org/W2068676048","https://openalex.org/W2074719170","https://openalex.org/W2078557482","https://openalex.org/W2082533648","https://openalex.org/W2102646918","https://openalex.org/W2103635115","https://openalex.org/W2109595484","https://openalex.org/W2112663699","https://openalex.org/W2119295078","https://openalex.org/W2122619490","https://openalex.org/W2128531352","https://openalex.org/W2143437405","https://openalex.org/W2143456396","https://openalex.org/W2148852502","https://openalex.org/W2153688789","https://openalex.org/W2155866163","https://openalex.org/W2158537070","https://openalex.org/W2158670726","https://openalex.org/W2168857275","https://openalex.org/W2172526540","https://openalex.org/W2275159387","https://openalex.org/W2285724671","https://openalex.org/W2425481741","https://openalex.org/W2580792129","https://openalex.org/W2587931238","https://openalex.org/W2594056938","https://openalex.org/W2680648889","https://openalex.org/W2689551416","https://openalex.org/W2739656566","https://openalex.org/W2742298653","https://openalex.org/W2787983500","https://openalex.org/W2807977210","https://openalex.org/W2905220718","https://openalex.org/W2914858370","https://openalex.org/W2921994518","https://openalex.org/W2951485519","https://openalex.org/W2955946889","https://openalex.org/W2972882588","https://openalex.org/W3002886130","https://openalex.org/W3026583983"],"related_works":["https://openalex.org/W2594056938","https://openalex.org/W7124440102","https://openalex.org/W3102771713","https://openalex.org/W7160513457","https://openalex.org/W2585930157","https://openalex.org/W3118937927","https://openalex.org/W2276218663","https://openalex.org/W4386392266","https://openalex.org/W2022841292","https://openalex.org/W4386580249"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-03-15T00:00:00"}