{"id":"https://openalex.org/W3133371979","doi":"https://doi.org/10.3390/metabo11020123","title":"Impact of Altered Gut Microbiota and Its Metabolites in Cystic Fibrosis","display_name":"Impact of Altered Gut Microbiota and Its Metabolites in Cystic Fibrosis","publication_year":2021,"publication_date":"2021-02-22","ids":{"openalex":"https://openalex.org/W3133371979","doi":"https://doi.org/10.3390/metabo11020123","mag":"3133371979","pmid":"https://pubmed.ncbi.nlm.nih.gov/33671639","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7926988"},"language":"en","primary_location":{"id":"doi:10.3390/metabo11020123","doi":"https://doi.org/10.3390/metabo11020123","is_oa":true,"landing_page_url":"https://doi.org/10.3390/metabo11020123","pdf_url":"https://www.mdpi.com/2218-1989/11/2/123/pdf?version=1614249746","source":{"id":"https://openalex.org/S2764402194","display_name":"Metabolites","issn_l":"2218-1989","issn":["2218-1989"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2218-1989/11/2/123/pdf?version=1614249746","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033818381","display_name":"Aravind Thavamani","orcid":"https://orcid.org/0000-0002-4966-5113","observed_orcids":["https://orcid.org/0000-0002-4966-5113"]},"institutions":[{"id":"https://openalex.org/I4210151235","display_name":"Rainbow Babies & Children's Hospital","ror":"https://ror.org/04x495f64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210151235"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aravind Thavamani","raw_affiliation_strings":["Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies &amp; Children\u2019s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA"],"raw_orcid":"https://orcid.org/0000-0002-4966-5113","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies &amp; Children\u2019s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210151235","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110597290","display_name":"Iman Salem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108791","display_name":"University Hospitals Cleveland Medical Center","ror":"https://ror.org/01gc0wp38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210108791"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Iman Salem","raw_affiliation_strings":["Center for Medial Mycology, Case Western Reserve University School of Medicine, UH Cleveland Medical Center, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Medial Mycology, Case Western Reserve University School of Medicine, UH Cleveland Medical Center, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210108791","https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080838490","display_name":"Thomas J. Sferra","orcid":"https://orcid.org/0000-0001-6893-9880","observed_orcids":["https://orcid.org/0000-0001-6893-9880"]},"institutions":[{"id":"https://openalex.org/I4210151235","display_name":"Rainbow Babies & Children's Hospital","ror":"https://ror.org/04x495f64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210151235"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas J. Sferra","raw_affiliation_strings":["Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies &amp; Children\u2019s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies &amp; Children\u2019s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210151235","https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077921396","display_name":"Senthilkumar Sankararaman","orcid":"https://orcid.org/0000-0003-3094-9703","observed_orcids":["https://orcid.org/0000-0003-3094-9703"]},"institutions":[{"id":"https://openalex.org/I4210151235","display_name":"Rainbow Babies & Children's Hospital","ror":"https://ror.org/04x495f64","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799343972","https://openalex.org/I4210151235"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Senthilkumar Sankararaman","raw_affiliation_strings":["Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies &amp; Children\u2019s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA"],"raw_orcid":"https://orcid.org/0000-0003-3094-9703","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatric Gastroenterology, UH Rainbow Babies &amp; Children\u2019s Hospital, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4210151235","https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5077921396"],"corresponding_institution_ids":["https://openalex.org/I4210151235","https://openalex.org/I58956616"],"apc_list":{"value":1800,"currency":"CHF","value_usd":1944},"apc_paid":{"value":1800,"currency":"CHF","value_usd":1944},"fwci":1.0706,"has_fulltext":true,"cited_by_count":66,"citation_normalized_percentile":{"value":0.742,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"11","issue":"2","first_page":"123","last_page":"123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.8080999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.8080999851226807,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.18649999797344208,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":1.0},{"id":"https://openalex.org/keywords/gut-dysbiosis","display_name":"gut dysbiosis","score":0.8690000176429749},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9369999766349792},{"id":"https://openalex.org/keywords/microbiome-metabolites","display_name":"microbiome metabolites","score":0.7080000042915344},{"id":"https://openalex.org/keywords/cftr","display_name":"CFTR","score":0.6809999942779541},{"id":"https://openalex.org/keywords/gastrointestinal-manifestations","display_name":"gastrointestinal manifestations","score":0.7360000014305115},{"id":"https://openalex.org/keywords/antibiotic-use","display_name":"antibiotic use","score":0.6819999814033508},{"id":"https://openalex.org/keywords/pulmonary-exacerbations","display_name":"pulmonary exacerbations","score":0.9599999785423279},{"id":"https://openalex.org/keywords/intestinal-homeostasis","display_name":"intestinal homeostasis","score":0.718999981880188}],"concepts":[{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.9240692853927612},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.8832595348358154},{"id":"https://openalex.org/C2778428886","wikidata":"https://www.wikidata.org/wiki/Q420470","display_name":"Cystic fibrosis transmembrane conductance regulator","level":3,"score":0.6211859583854675},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.5861495137214661},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.5022625923156738},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4457036554813385},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.44348978996276855},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4357559084892273},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39247214794158936},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3011544644832611},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2615751028060913}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/metabo11020123","doi":"https://doi.org/10.3390/metabo11020123","is_oa":true,"landing_page_url":"https://doi.org/10.3390/metabo11020123","pdf_url":"https://www.mdpi.com/2218-1989/11/2/123/pdf?version=1614249746","source":{"id":"https://openalex.org/S2764402194","display_name":"Metabolites","issn_l":"2218-1989","issn":["2218-1989"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7926988","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7926988","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"Text"},{"id":"pmid:33671639","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33671639","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:7b5e7ab487d549d0a5c3b16827683037","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7b5e7ab487d549d0a5c3b16827683037","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Metabolites, Vol 11, Iss 2, p 123 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/metabo11020123","doi":"https://doi.org/10.3390/metabo11020123","is_oa":true,"landing_page_url":"https://doi.org/10.3390/metabo11020123","pdf_url":"https://www.mdpi.com/2218-1989/11/2/123/pdf?version=1614249746","source":{"id":"https://openalex.org/S2764402194","display_name":"Metabolites","issn_l":"2218-1989","issn":["2218-1989"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolites","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306168","display_name":"Cystic Fibrosis Foundation","ror":"https://ror.org/00ax59295"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3133371979.pdf","grobid_xml":"https://content.openalex.org/works/W3133371979.grobid-xml"},"referenced_works_count":111,"referenced_works":["https://openalex.org/W167809514","https://openalex.org/W1167511716","https://openalex.org/W1171996912","https://openalex.org/W1544875169","https://openalex.org/W1576703428","https://openalex.org/W1860016805","https://openalex.org/W1968282405","https://openalex.org/W1993611202","https://openalex.org/W2002646600","https://openalex.org/W2007935931","https://openalex.org/W2012606594","https://openalex.org/W2015289081","https://openalex.org/W2016073847","https://openalex.org/W2018442187","https://openalex.org/W2043011411","https://openalex.org/W2045119680","https://openalex.org/W2065493165","https://openalex.org/W2066754577","https://openalex.org/W2080081206","https://openalex.org/W2083953573","https://openalex.org/W2087127819","https://openalex.org/W2087292184","https://openalex.org/W2088394751","https://openalex.org/W2092725930","https://openalex.org/W2094624871","https://openalex.org/W2105997404","https://openalex.org/W2111857260","https://openalex.org/W2122147174","https://openalex.org/W2140212995","https://openalex.org/W2141980700","https://openalex.org/W2142231009","https://openalex.org/W2144287907","https://openalex.org/W2144754352","https://openalex.org/W2148935969","https://openalex.org/W2158409478","https://openalex.org/W2159649357","https://openalex.org/W2160079691","https://openalex.org/W2161332823","https://openalex.org/W2162088497","https://openalex.org/W2166562121","https://openalex.org/W2166885190","https://openalex.org/W2213284782","https://openalex.org/W2234246985","https://openalex.org/W2268930221","https://openalex.org/W2288780584","https://openalex.org/W2292347922","https://openalex.org/W2293237171","https://openalex.org/W2317186553","https://openalex.org/W2345330757","https://openalex.org/W2512322023","https://openalex.org/W2515118880","https://openalex.org/W2517799086","https://openalex.org/W2520098753","https://openalex.org/W2527532032","https://openalex.org/W2528396364","https://openalex.org/W2547397706","https://openalex.org/W2584800157","https://openalex.org/W2586444320","https://openalex.org/W2590171893","https://openalex.org/W2590939865","https://openalex.org/W2591617823","https://openalex.org/W2602458814","https://openalex.org/W2606185690","https://openalex.org/W2610173957","https://openalex.org/W2611117343","https://openalex.org/W2738761780","https://openalex.org/W2738924012","https://openalex.org/W2771485505","https://openalex.org/W2780443557","https://openalex.org/W2783843471","https://openalex.org/W2789290094","https://openalex.org/W2793689629","https://openalex.org/W2799606914","https://openalex.org/W2803148575","https://openalex.org/W2806967055","https://openalex.org/W2809478295","https://openalex.org/W2884535000","https://openalex.org/W2890526629","https://openalex.org/W2891663102","https://openalex.org/W2893427474","https://openalex.org/W2896038997","https://openalex.org/W2897319020","https://openalex.org/W2898601962","https://openalex.org/W2898728444","https://openalex.org/W2899102155","https://openalex.org/W2901052865","https://openalex.org/W2904356223","https://openalex.org/W2905475552","https://openalex.org/W2909668868","https://openalex.org/W2921966151","https://openalex.org/W2939196448","https://openalex.org/W2944622567","https://openalex.org/W2948246500","https://openalex.org/W2950905772","https://openalex.org/W2976998228","https://openalex.org/W2992043930","https://openalex.org/W2999065630","https://openalex.org/W3000104810","https://openalex.org/W3002179032","https://openalex.org/W3003518864","https://openalex.org/W3003742251","https://openalex.org/W3007329745","https://openalex.org/W3015909347","https://openalex.org/W3018582544","https://openalex.org/W3023514173","https://openalex.org/W3023968747","https://openalex.org/W3027632119","https://openalex.org/W3031637004","https://openalex.org/W3045550518","https://openalex.org/W3081903337","https://openalex.org/W4231884090"],"related_works":["https://openalex.org/W4414069618","https://openalex.org/W6944354892","https://openalex.org/W2293237171","https://openalex.org/W4210594664","https://openalex.org/W6964720269","https://openalex.org/W2905475552","https://openalex.org/W4313468583","https://openalex.org/W2292347922","https://openalex.org/W2738924012","https://openalex.org/W4205127929"],"abstract_inverted_index":{"Cystic":[0],"fibrosis":[1,20],"(CF)":[2],"is":[3,82],"the":[4,15,18,56,76,98,115,133],"most":[5],"common":[6],"lethal,":[7],"multisystemic":[8],"genetic":[9],"disorder":[10],"in":[11,14,47,51,59,108,119],"Caucasians.":[12],"Mutations":[13],"gene":[16],"encoding":[17],"cystic":[19],"transmembrane":[21],"regulator":[22],"(CFTR)":[23],"protein":[24],"are":[25],"responsible":[26],"for":[27,93],"impairment":[28],"of":[29,63,70,75,80,91,124,135],"epithelial":[30],"anionic":[31],"transport,":[32],"leading":[33],"to":[34,73,148],"impaired":[35],"fluid":[36],"regulation":[37],"and":[38,53,101,112,127,138,145],"pH":[39],"imbalance":[40],"across":[41],"multiple":[42],"organs.":[43],"Gastrointestinal":[44],"(GI)":[45],"manifestations":[46,123],"CF":[48,143],"may":[49],"begin":[50],"utero":[52],"continue":[54],"throughout":[55],"life,":[57],"resulting":[58],"a":[60,105],"chronic":[61],"state":[62,79],"an":[64],"altered":[65],"intestinal":[66],"milieu.":[67],"Inherent":[68],"dysfunction":[69],"CFTR":[71],"leads":[72],"dysbiosis":[74,81,117,137],"gut.":[77],"This":[78,129],"further":[83],"perpetuated":[84],"by":[85],"acquired":[86],"factors":[87],"such":[88],"as":[89],"use":[90],"antibiotics":[92],"recurrent":[94],"pulmonary":[95],"exacerbations.":[96],"Since":[97],"gastrointestinal":[99],"microbiome":[100],"their":[102],"metabolites":[103],"play":[104],"vital":[106],"role":[107],"nutrition,":[109],"metabolic,":[110],"inflammatory,":[111],"immune":[113],"functions,":[114],"gut":[116,136],"will":[118],"turn":[120],"impact":[121],"various":[122],"CF-both":[125],"GI":[126],"extra-GI.":[128],"review":[130],"focuses":[131],"on":[132,142],"consequences":[134],"its":[139],"metabolic":[140],"implications":[141],"disease":[144],"possible":[146],"ways":[147],"restore":[149],"homeostasis.":[150]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2021-03-01T00:00:00"}
