{"id":"https://openalex.org/W3133045937","doi":"https://doi.org/10.1186/s13099-021-00409-5","title":"Ectopic gut colonization: a metagenomic study of the oral and gut microbiome in Crohn\u2019s disease","display_name":"Ectopic gut colonization: a metagenomic study of the oral and gut microbiome in Crohn\u2019s disease","publication_year":2021,"publication_date":"2021-02-25","ids":{"openalex":"https://openalex.org/W3133045937","doi":"https://doi.org/10.1186/s13099-021-00409-5","mag":"3133045937","pmid":"https://pubmed.ncbi.nlm.nih.gov/33632307","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7905567"},"language":"en","primary_location":{"id":"doi:10.1186/s13099-021-00409-5","doi":"https://doi.org/10.1186/s13099-021-00409-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13099-021-00409-5","pdf_url":"https://gutpathogens.biomedcentral.com/track/pdf/10.1186/s13099-021-00409-5","source":{"id":"https://openalex.org/S116933238","display_name":"Gut Pathogens","issn_l":"1757-4749","issn":["1757-4749"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut Pathogens","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://gutpathogens.biomedcentral.com/track/pdf/10.1186/s13099-021-00409-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072612407","display_name":"Shijia Hu","orcid":"https://orcid.org/0000-0001-6136-9926","observed_orcids":["https://orcid.org/0000-0001-6136-9926"]},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Shijia Hu","raw_affiliation_strings":["Discipline of Orthodontics and Paediatric Dentistry, Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore, 119085, Singapore. Shijia_hu@nuhs.edu.sg","Discipline of Orthodontics and Paediatric Dentistry, Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore, 119085, Singapore"],"raw_orcid":"https://orcid.org/0000-0001-6136-9926","affiliations":[{"raw_affiliation_string":"Discipline of Orthodontics and Paediatric Dentistry, Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore, 119085, Singapore. Shijia_hu@nuhs.edu.sg","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"Discipline of Orthodontics and Paediatric Dentistry, Faculty of Dentistry, National University of Singapore, 9 Lower Kent Ridge Road, Singapore, 119085, Singapore","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010212932","display_name":"Eileen Png","orcid":"https://orcid.org/0000-0001-5586-6395","observed_orcids":["https://orcid.org/0000-0001-5586-6395"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Eileen Png","raw_affiliation_strings":["Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065134734","display_name":"Michelle Gowans","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"id":"https://openalex.org/I4210150261","display_name":"National University Health System","ror":"https://ror.org/05tjjsh18","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Michelle Gowans","raw_affiliation_strings":["Division of Gastroenterology & Hepatology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology & Hepatology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore","institution_ids":["https://openalex.org/I4210146690","https://openalex.org/I4210150261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102730871","display_name":"David Eng Hui Ong","orcid":"https://orcid.org/0000-0002-4953-8042","observed_orcids":["https://orcid.org/0000-0002-4953-8042"]},"institutions":[{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]},{"id":"https://openalex.org/I4210150261","display_name":"National University Health System","ror":"https://ror.org/05tjjsh18","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"David E. H. Ong","raw_affiliation_strings":["Division of Gastroenterology & Hepatology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology & Hepatology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore","institution_ids":["https://openalex.org/I4210146690","https://openalex.org/I4210150261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037793217","display_name":"Paola Fl\u00f3rez de Sessions","orcid":"https://orcid.org/0000-0003-0258-9616","observed_orcids":["https://orcid.org/0000-0003-0258-9616"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Paola Florez de Sessions","raw_affiliation_strings":["Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100612519","display_name":"Jie Song","orcid":"https://orcid.org/0000-0003-1144-1971","observed_orcids":["https://orcid.org/0000-0003-1144-1971"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jie Song","raw_affiliation_strings":["Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062774997","display_name":"Niranjan Nagarajan","orcid":"https://orcid.org/0000-0003-0850-5604","observed_orcids":["https://orcid.org/0000-0003-0850-5604"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Niranjan Nagarajan","raw_affiliation_strings":["Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore","Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 60 Biopolis St, Singapore, 138672, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I66068411"]},{"raw_affiliation_string":"Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5072612407"],"corresponding_institution_ids":["https://openalex.org/I165932596"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":2.803,"has_fulltext":true,"cited_by_count":60,"citation_normalized_percentile":{"value":0.93244059,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"13","issue":"1","first_page":"13","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.9067000150680542,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.08969999849796295,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":1.0},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9070000052452087},{"id":"https://openalex.org/keywords/oral-microbiota","display_name":"oral microbiota","score":1.0},{"id":"https://openalex.org/keywords/streptococcus-salivarius","display_name":"Streptococcus salivarius","score":0.8870000243186951},{"id":"https://openalex.org/keywords/faecalibacterium-prausnitzii","display_name":"Faecalibacterium prausnitzii","score":0.8830000162124634},{"id":"https://openalex.org/keywords/roseburia-inulinivorans","display_name":"Roseburia inulinivorans","score":0.8309999704360962},{"id":"https://openalex.org/keywords/ruminococcus-gnavus","display_name":"Ruminococcus gnavus","score":0.9300000071525574},{"id":"https://openalex.org/keywords/crohn-s-disease-activity-index","display_name":"CDAI","score":0.7720000147819519},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.47600001096725464}],"concepts":[{"id":"https://openalex.org/C2776706654","wikidata":"https://www.wikidata.org/wiki/Q3941444","display_name":"Roseburia","level":4,"score":0.8947443962097168},{"id":"https://openalex.org/C2780675110","wikidata":"https://www.wikidata.org/wiki/Q3738294","display_name":"Faecalibacterium prausnitzii","level":3,"score":0.8309030532836914},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.7205772399902344},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.6521927118301392},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.5823620557785034},{"id":"https://openalex.org/C2779280984","wikidata":"https://www.wikidata.org/wiki/Q1472","display_name":"Crohn's disease","level":3,"score":0.5375620126724243},{"id":"https://openalex.org/C101985253","wikidata":"https://www.wikidata.org/wiki/Q1073526","display_name":"Shotgun sequencing","level":4,"score":0.5203604102134705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5051103234291077},{"id":"https://openalex.org/C2780960513","wikidata":"https://www.wikidata.org/wiki/Q2720082","display_name":"Fusobacterium","level":4,"score":0.4942179024219513},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.4899064898490906},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.4639885425567627},{"id":"https://openalex.org/C2778271842","wikidata":"https://www.wikidata.org/wiki/Q838966","display_name":"Irritable bowel syndrome","level":2,"score":0.4603320062160492},{"id":"https://openalex.org/C2910160754","wikidata":"https://www.wikidata.org/wiki/Q1500347","display_name":"Oral Microbiome","level":3,"score":0.441936194896698},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.4359545111656189},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4351697862148285},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.42063817381858826},{"id":"https://openalex.org/C2778168646","wikidata":"https://www.wikidata.org/wiki/Q133186","display_name":"Bacteroides","level":3,"score":0.405697762966156},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40064379572868347},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.39722302556037903},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3720127046108246},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31283891201019287},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17178520560264587},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.11696738004684448},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11660337448120117},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.10849007964134216}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1186/s13099-021-00409-5","doi":"https://doi.org/10.1186/s13099-021-00409-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13099-021-00409-5","pdf_url":"https://gutpathogens.biomedcentral.com/track/pdf/10.1186/s13099-021-00409-5","source":{"id":"https://openalex.org/S116933238","display_name":"Gut Pathogens","issn_l":"1757-4749","issn":["1757-4749"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut Pathogens","raw_type":"journal-article"},{"id":"pmid:33632307","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33632307","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut pathogens","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7905567","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7905567/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut Pathog","raw_type":"Text"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/230946","doi":null,"is_oa":false,"landing_page_url":"https://scholarbank.nus.edu.sg/handle/10635/230946","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Elements","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:3a6adba2273841f3b0972761095a96be","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/3a6adba2273841f3b0972761095a96be","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Gut Pathogens, Vol 13, Iss 1, Pp 1-13 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s13099-021-00409-5","doi":"https://doi.org/10.1186/s13099-021-00409-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13099-021-00409-5","pdf_url":"https://gutpathogens.biomedcentral.com/track/pdf/10.1186/s13099-021-00409-5","source":{"id":"https://openalex.org/S116933238","display_name":"Gut Pathogens","issn_l":"1757-4749","issn":["1757-4749"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut Pathogens","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320698","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3133045937.pdf","grobid_xml":"https://content.openalex.org/works/W3133045937.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1132560470","https://openalex.org/W1497287772","https://openalex.org/W1703384511","https://openalex.org/W1930641188","https://openalex.org/W1980370660","https://openalex.org/W1992713819","https://openalex.org/W2003525072","https://openalex.org/W2026074634","https://openalex.org/W2026707952","https://openalex.org/W2028520715","https://openalex.org/W2030491651","https://openalex.org/W2048093113","https://openalex.org/W2069580163","https://openalex.org/W2085284704","https://openalex.org/W2095680943","https://openalex.org/W2098038682","https://openalex.org/W2106733239","https://openalex.org/W2112635226","https://openalex.org/W2115524426","https://openalex.org/W2130388822","https://openalex.org/W2141125135","https://openalex.org/W2143777796","https://openalex.org/W2144213049","https://openalex.org/W2150059507","https://openalex.org/W2155660329","https://openalex.org/W2160734881","https://openalex.org/W2164265873","https://openalex.org/W2167333965","https://openalex.org/W2182578492","https://openalex.org/W2282772932","https://openalex.org/W2396875676","https://openalex.org/W2522491625","https://openalex.org/W2586360538","https://openalex.org/W2594503735","https://openalex.org/W2618503740","https://openalex.org/W2719563224","https://openalex.org/W2739518188","https://openalex.org/W2767008704","https://openalex.org/W2776445964","https://openalex.org/W2805008860","https://openalex.org/W2897682193","https://openalex.org/W2947189704","https://openalex.org/W2950245396","https://openalex.org/W2951518977","https://openalex.org/W2972546592","https://openalex.org/W3028823705","https://openalex.org/W3035326193","https://openalex.org/W3149527659","https://openalex.org/W4394666350"],"related_works":["https://openalex.org/W4391161428","https://openalex.org/W4225957446","https://openalex.org/W3204829941","https://openalex.org/W7160333039","https://openalex.org/W4286503797","https://openalex.org/W4391162766","https://openalex.org/W2622530782","https://openalex.org/W4311432966","https://openalex.org/W4223985705","https://openalex.org/W2042172193"],"abstract_inverted_index":{"BACKGROUND:":[0],"This":[1,125],"study":[2,31,91],"aims":[3],"to":[4,46,108,162,169,220,291,301],"characterize,":[5],"the":[6,116,277],"gut":[7,61,117,259,270,284],"and":[8,35,53,62,72,82,97,111,118,148,154,191,209,242],"oral":[9,50,63,102,119,273],"microbiome":[10,64,120,260,314],"in":[11,115,129,166,229,258,289,307],"Asian":[12],"subjects":[13,43,94,131,231,302],"with":[14,32,95,132],"Crohn's":[15,122,134,262],"disease":[16,123,150],"(CD)":[17],"using":[18],"whole":[19],"genome":[20],"shotgun":[21],"sequencing,":[22],"thereby":[23],"allowing":[24],"for":[25,58,313],"strain-level":[26],"comparison.":[27],"METHODS:":[28],"A":[29],"case-control":[30],"age,":[33],"sex":[34],"ethnicity":[36],"matched":[37],"healthy":[38,99],"controls":[39],"was":[40,106,126,226,266],"conducted.":[41,88],"CD":[42,96,130,167,230],"were":[44,56,68,87,218,250,287],"limited":[45],"well-controlled":[47],"patients":[48],"without":[49],"manifestations.":[51],"Fecal":[52],"saliva":[54],"samples":[55],"collected":[57],"characterization":[59],"of":[60,112,121,232,261,268,280,303],"respectively.":[65],"Microbial":[66,235],"DNA":[67],"extracted,":[69],"libraries":[70],"prepared":[71],"sequenced":[73],"reads":[74],"profiled.":[75],"Taxonomic":[76],"diversity,":[77],"taxonomic":[78],"association,":[79],"strain":[80],"typing":[81],"microbial":[83,285,308],"gene":[84],"pathway":[85],"analyses":[86],"RESULTS:":[89],"The":[90,101],"recruited":[92],"25":[93,98],"controls.":[100],"microbe":[103],"Streptococcus":[104],"salivarius":[105],"found":[107,161,219,228,251],"be":[109,163,221],"enriched":[110],"concordant":[113],"strains":[114],"subjects.":[124],"more":[127],"likely":[128],"higher":[133,254],"Disease":[135],"Activity":[136],"Index":[137],"(184.3":[138],"\u00b1":[139,143],"2.9":[140],"vs":[141,178,186,195,204,213],"67.1":[142],"82.5,":[144],"p":[145,180,188,197,206,215,239,246],"=":[146,157,181,189,198,207,216,240],"0.012)":[147],"active":[149,278],"status":[151],"(Diarrhoea/abdominal":[152],"pain/blood-in-stool/fever":[153],"fatigue)":[155],"(p":[156],"0.016).":[158],"Gut":[159],"species":[160],"significantly":[164],"depleted":[165],"compared":[168],"control":[170],"(Relative":[171],"abundance:":[172],"Median[Range])":[173],"include:":[174],"Faecalibacterium":[175],"prausnitzii":[176],"(0.03[0.00-4.56]":[177],"13.69[5.32-18.71],":[179],"0.010),":[182],"Roseburia":[183],"inulinivorans":[184],"(0.00[0.00-0.03]":[185],"0.21[0.01-0.53],":[187],"0.010)":[190],"Alistipes":[192],"senegalensis":[193],"(0.00[0.00-0.00]":[194],"0.00[0.00-0.02],":[196],"0.029).":[199],"While":[200],"Clostridium":[201],"nexile":[202,224],"(0.00[0.00-0.12]":[203],"0.00[0.00-0.00],":[205],"0.038)":[208],"Ruminococcus":[210],"gnavus":[211],"(0.43[0.02-0.33]":[212],"0.00[0.00-0.13],":[214],"0.043)":[217],"enriched.":[222],"C.":[223],"enrichment":[225],"not":[227],"European":[233,304],"descent.":[234,305],"arginine":[236],"(Linear-discriminant-analysis:":[237,244],"3.162,":[238],"0.001)":[241,248],"isoprene":[243],"3.058,":[245],"<":[247],"pathways":[249,309],"at":[252],"a":[253],"relative":[255],"abundance":[256],"level":[257],"disease.":[263],"CONCLUSIONS:":[264],"There":[265],"evidence":[267],"ectopic":[269],"colonization":[271],"by":[272],"bacteria,":[274],"especially":[275],"during":[276],"phase":[279],"CD.":[281],"Previously":[282],"studied":[283],"differences":[286,300],"detected,":[288],"addition":[290],"novel":[292],"associations":[293],"which":[294],"could":[295],"have":[296],"resulted":[297],"from":[298],"geographical/ethnic":[299],"Differences":[306],"provide":[310],"possible":[311],"targets":[312],"modification.":[315]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":13}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2021-03-01T00:00:00"}