{"id":"https://openalex.org/W3132221372","doi":"https://doi.org/10.1038/s41591-021-01281-1","title":"A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity","display_name":"A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity","publication_year":2021,"publication_date":"2021-02-25","ids":{"openalex":"https://openalex.org/W3132221372","doi":"https://doi.org/10.1038/s41591-021-01281-1","mag":"3132221372","pmid":"https://pubmed.ncbi.nlm.nih.gov/33633408"},"language":"en","primary_location":{"id":"doi:10.1038/s41591-021-01281-1","doi":"https://doi.org/10.1038/s41591-021-01281-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41591-021-01281-1","pdf_url":"https://www.nature.com/articles/s41591-021-01281-1.pdf","source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nature.com/articles/s41591-021-01281-1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058556843","display_name":"Sirui Zhou","orcid":"https://orcid.org/0000-0003-4963-0815","observed_orcids":["https://orcid.org/0000-0003-4963-0815"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sirui Zhou","raw_affiliation_strings":["Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088367550","display_name":"Guillaume Butler\u2010Laporte","orcid":"https://orcid.org/0000-0001-5388-0396","observed_orcids":["https://orcid.org/0000-0001-5388-0396"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Guillaume Butler-Laporte","raw_affiliation_strings":["Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0001-5388-0396","affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048891278","display_name":"Tomoko Nakanishi","orcid":"https://orcid.org/0000-0001-9510-5646","observed_orcids":["https://orcid.org/0000-0001-9510-5646"]},"institutions":[{"id":"https://openalex.org/I205924995","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I1319490839","https://openalex.org/I205924995"]},{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA","JP"],"is_corresponding":false,"raw_author_name":"Tomoko Nakanishi","raw_affiliation_strings":["Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada","Kyoto-McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","Research Fellow, Japan Society for the Promotion of Science, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0001-9510-5646","affiliations":[{"raw_affiliation_string":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Kyoto-McGill International Collaborative School in Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]},{"raw_affiliation_string":"Research Fellow, Japan Society for the Promotion of Science, Tokyo, Japan","institution_ids":["https://openalex.org/I205924995"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066900496","display_name":"David Morrison","orcid":"https://orcid.org/0000-0001-8380-3615","observed_orcids":["https://orcid.org/0000-0001-8380-3615"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"David R. Morrison","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0001-8380-3615","affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072402610","display_name":"Jonathan Afilalo","orcid":"https://orcid.org/0000-0003-0555-4937","observed_orcids":["https://orcid.org/0000-0003-0555-4937"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jonathan Afilalo","raw_affiliation_strings":["Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","Department of Medicine, Division of Cardiology, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Department of Medicine, Division of Cardiology, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031794382","display_name":"Marc Afilalo","orcid":"https://orcid.org/0000-0002-0211-3418","observed_orcids":["https://orcid.org/0000-0002-0211-3418"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marc Afilalo","raw_affiliation_strings":["Department of Emergency Medicine, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Emergency Medicine, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Laetitia Laurent","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Laetitia Laurent","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008046650","display_name":"Maik Pietzner","orcid":"https://orcid.org/0000-0003-3437-9963","observed_orcids":["https://orcid.org/0000-0003-3437-9963"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210158597","display_name":"MRC Epidemiology Unit","ror":"https://ror.org/052578691","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210158597","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Maik Pietzner","raw_affiliation_strings":["MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210158597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106630383","display_name":"Nicola D. Kerrison","orcid":"https://orcid.org/0000-0002-1471-953X","observed_orcids":["https://orcid.org/0000-0002-1471-953X"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210158597","display_name":"MRC Epidemiology Unit","ror":"https://ror.org/052578691","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210158597","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicola Kerrison","raw_affiliation_strings":["MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210158597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003905817","display_name":"Kaiqiong Zhao","orcid":"https://orcid.org/0000-0003-0810-8764","observed_orcids":["https://orcid.org/0000-0003-0810-8764"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kaiqiong Zhao","raw_affiliation_strings":["Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022491312","display_name":"Elsa Brunet\u2010Ratnasingham","orcid":"https://orcid.org/0000-0002-3613-1315","observed_orcids":["https://orcid.org/0000-0002-3613-1315"]},"institutions":[{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Elsa Brunet-Ratnasingham","raw_affiliation_strings":["Department of Microbiology, Infectiology and Immunology, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0002-3613-1315","affiliations":[{"raw_affiliation_string":"Department of Microbiology, Infectiology and Immunology, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I70931966"]},{"raw_affiliation_string":"Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004547660","display_name":"Danielle Henry","orcid":"https://orcid.org/0000-0001-8851-7968","observed_orcids":["https://orcid.org/0000-0001-8851-7968"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Danielle Henry","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072891198","display_name":"Nofar Kimchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nofar Kimchi","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055087767","display_name":"Zaman Afrasiabi","orcid":"https://orcid.org/0000-0003-4395-5168","observed_orcids":["https://orcid.org/0000-0003-4395-5168"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Zaman Afrasiabi","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0003-4395-5168","affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065454991","display_name":"Nardin Rezk","orcid":"https://orcid.org/0000-0001-5358-7704","observed_orcids":["https://orcid.org/0000-0001-5358-7704"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nardin Rezk","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0001-5358-7704","affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012706257","display_name":"Meriem Bouab","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Meriem Bouab","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055150531","display_name":"Louis Petitjean","orcid":"https://orcid.org/0000-0002-9223-5100","observed_orcids":["https://orcid.org/0000-0002-9223-5100"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Louis Petitjean","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0002-9223-5100","affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048095869","display_name":"Charlotte Guzman","orcid":"https://orcid.org/0000-0002-2979-4436","observed_orcids":["https://orcid.org/0000-0002-2979-4436"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Charlotte Guzman","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0002-2979-4436","affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109520643","display_name":"Xiaoqing Xue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Xiaoqing Xue","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029649627","display_name":"Chris Tselios","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Chris Tselios","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052503390","display_name":"Branka Vulesevic","orcid":"https://orcid.org/0000-0003-2297-2209","observed_orcids":["https://orcid.org/0000-0003-2297-2209","https://orcid.org/0000-0002-3660-5410"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Branka Vulesevic","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104112265","display_name":"Olumide Adeleye","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Olumide Adeleye","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006129040","display_name":"Tala Abdullah","orcid":"https://orcid.org/0000-0002-7195-5045","observed_orcids":["https://orcid.org/0000-0002-7195-5045"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Tala Abdullah","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022470482","display_name":"Noor Almamlouk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Noor Almamlouk","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101702025","display_name":"Yiheng Chen","orcid":"https://orcid.org/0000-0002-7662-9441","observed_orcids":["https://orcid.org/0000-0002-7662-9441"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Yiheng Chen","raw_affiliation_strings":["Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003074300","display_name":"Micha\u00ebl Chass\u00e9","orcid":"https://orcid.org/0000-0001-7075-1924","observed_orcids":["https://orcid.org/0000-0001-7075-1924"]},"institutions":[{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Micha\u00ebl Chass\u00e9","raw_affiliation_strings":["Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012588553","display_name":"Mad\u00e9leine Durand","orcid":"https://orcid.org/0000-0002-9459-9549","observed_orcids":["https://orcid.org/0000-0002-9459-9549"]},"institutions":[{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Madeleine Durand","raw_affiliation_strings":["Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I4210142730"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017493524","display_name":"Clare Paterson","orcid":"https://orcid.org/0000-0001-7454-560X","observed_orcids":["https://orcid.org/0000-0001-7454-560X"]},"institutions":[{"id":"https://openalex.org/I4210098892","display_name":"SomaLogic (United States)","ror":"https://ror.org/00yvkcc48","country_code":"US","type":"company","lineage":["https://openalex.org/I4210098892"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clare Paterson","raw_affiliation_strings":["SomaLogic, Inc., Boulder, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"SomaLogic, Inc., Boulder, CO, USA","institution_ids":["https://openalex.org/I4210098892"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041855330","display_name":"Johan Normark","orcid":"https://orcid.org/0000-0001-5831-4369","observed_orcids":["https://orcid.org/0000-0001-5831-4369"]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johan Normark","raw_affiliation_strings":["Molecular Infection Medicine Sweden (MIMS) and Wallenberg Center for Molecular Medicine, Department of Clinical Microbiology, Section of Infection and Immunology, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Infection Medicine Sweden (MIMS) and Wallenberg Center for Molecular Medicine, Department of Clinical Microbiology, Section of Infection and Immunology, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086044054","display_name":"Robert Frithiof","orcid":"https://orcid.org/0000-0003-2278-7951","observed_orcids":["https://orcid.org/0000-0003-2278-7951"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Robert Frithiof","raw_affiliation_strings":["Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-2278-7951","affiliations":[{"raw_affiliation_string":"Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043684931","display_name":"Mikl\u00f3s Lipcsey","orcid":"https://orcid.org/0000-0002-1976-4129","observed_orcids":["https://orcid.org/0000-0002-1976-4129"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Mikl\u00f3s Lipcsey","raw_affiliation_strings":["Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden","Hedenstierna Laboratory, CIRRUS, Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"Hedenstierna Laboratory, CIRRUS, Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043078981","display_name":"Michael Hultstr\u00f6m","orcid":"https://orcid.org/0000-0003-4675-1099","observed_orcids":["https://orcid.org/0000-0003-4675-1099","https://orcid.org/0000-0001-7118-1249"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Michael Hultstr\u00f6m","raw_affiliation_strings":["Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden","Integrative Physiology, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden"],"raw_orcid":"https://orcid.org/0000-0003-4675-1099","affiliations":[{"raw_affiliation_string":"Anaesthesiology and Intensive Care Medicine, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]},{"raw_affiliation_string":"Integrative Physiology, Department of Medical Cell Biology, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010018617","display_name":"Celia M.T. Greenwood","orcid":"https://orcid.org/0000-0002-2427-5696","observed_orcids":["https://orcid.org/0000-0002-2427-5696"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Celia M. T. Greenwood","raw_affiliation_strings":["Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","Gerald Bronfman Department of Oncology, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0002-2427-5696","affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Gerald Bronfman Department of Oncology, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038144368","display_name":"Hugo Zeberg","orcid":"https://orcid.org/0000-0001-7118-1249","observed_orcids":["https://orcid.org/0000-0001-7118-1249"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Hugo Zeberg","raw_affiliation_strings":["Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055584673","display_name":"Claudia Langenberg","orcid":"https://orcid.org/0000-0002-5017-7344","observed_orcids":["https://orcid.org/0000-0002-5017-7344","https://orcid.org/0000-0002-1305-0774"]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]},{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I4210158597","display_name":"MRC Epidemiology Unit","ror":"https://ror.org/052578691","country_code":"GB","type":"facility","lineage":["https://openalex.org/I241749","https://openalex.org/I4210087105","https://openalex.org/I4210158597","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE","GB"],"is_corresponding":false,"raw_author_name":"Claudia Langenberg","raw_affiliation_strings":["Computational Medicine, Berlin Institute of Health, Charit\u00e9 University Medicine Berlin, Berlin, Germany","MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK"],"raw_orcid":"https://orcid.org/0000-0002-5017-7344","affiliations":[{"raw_affiliation_string":"Computational Medicine, Berlin Institute of Health, Charit\u00e9 University Medicine Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]},{"raw_affiliation_string":"MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK","institution_ids":["https://openalex.org/I241749","https://openalex.org/I4210158597"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085935506","display_name":"Elin Thysell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I90267481","display_name":"Ume\u00e5 University","ror":"https://ror.org/05kb8h459","country_code":"SE","type":"education","lineage":["https://openalex.org/I90267481"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Elin Thysell","raw_affiliation_strings":["Department of Medical Biosciences, Pathology, Ume\u00e5 University, Ume\u00e5, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biosciences, Pathology, Ume\u00e5 University, Ume\u00e5, Sweden","institution_ids":["https://openalex.org/I90267481"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005616347","display_name":"Micha\u00ebl Pollak","orcid":"https://orcid.org/0000-0003-3047-0604","observed_orcids":["https://orcid.org/0000-0003-3047-0604"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Michael Pollak","raw_affiliation_strings":["Departments of Medicine and Oncology, McGill University, Montr\u00e9al, Quebec, Canada","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine and Oncology, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101550631","display_name":"Vincent Mooser","orcid":"https://orcid.org/0000-0002-8632-0448","observed_orcids":["https://orcid.org/0000-0002-8632-0448"]},"institutions":[{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Vincent Mooser","raw_affiliation_strings":["Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047621888","display_name":"Vincenzo Forgetta","orcid":"https://orcid.org/0000-0002-6061-4720","observed_orcids":["https://orcid.org/0000-0002-6061-4720","https://orcid.org/0000-0002-9286-0360"]},"institutions":[{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Vincenzo Forgetta","raw_affiliation_strings":["Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078444774","display_name":"DE Kaufmann","orcid":"https://orcid.org/0000-0003-4467-136X","observed_orcids":["https://orcid.org/0000-0003-4467-136X"]},"institutions":[{"id":"https://openalex.org/I4210142730","display_name":"Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0410a8y51","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4210142730","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I70931966","display_name":"Universit\u00e9 de Montr\u00e9al","ror":"https://ror.org/0161xgx34","country_code":"CA","type":"education","lineage":["https://openalex.org/I70931966"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Daniel E. Kaufmann","raw_affiliation_strings":["Department of Medicine, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0003-4467-136X","affiliations":[{"raw_affiliation_string":"Department of Medicine, Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I70931966"]},{"raw_affiliation_string":"Research Centre of the Centre Hospitalier de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I4210142730"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035461704","display_name":"John Brent Richards","orcid":"https://orcid.org/0000-0002-3746-9086","observed_orcids":["https://orcid.org/0000-0002-3746-9086","https://orcid.org/0000-0003-2613-0308"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I2801824472","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I4405267356","display_name":"Lady Davis Institute for Medical Research","ror":"https://ror.org/02c1np254","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801824472","https://openalex.org/I2801902503","https://openalex.org/I4210139015","https://openalex.org/I4405256057","https://openalex.org/I4405267356","https://openalex.org/I4405279980"]},{"id":"https://openalex.org/I5023651","display_name":"McGill University","ror":"https://ror.org/01pxwe438","country_code":"CA","type":"education","lineage":["https://openalex.org/I5023651"]}],"countries":["CA","GB"],"is_corresponding":true,"raw_author_name":"J. Brent Richards","raw_affiliation_strings":["Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada. brent.richards@mcgill.ca","Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada. brent.richards@mcgill.ca","Department of Twin Research, King's College London, London, UK. brent.richards@mcgill.ca","Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada. brent.richards@mcgill.ca","Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada"],"raw_orcid":"https://orcid.org/0000-0002-3746-9086","affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montr\u00e9al, Quebec, Canada. brent.richards@mcgill.ca","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada. brent.richards@mcgill.ca","institution_ids":["https://openalex.org/I5023651"]},{"raw_affiliation_string":"Department of Twin Research, King's College London, London, UK. brent.richards@mcgill.ca","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"Lady Davis Institute, Jewish General Hospital, McGill University, Montr\u00e9al, Quebec, Canada. brent.richards@mcgill.ca","institution_ids":["https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"]},{"raw_affiliation_string":"Department of Human Genetics, McGill University, Montr\u00e9al, Quebec, Canada","institution_ids":["https://openalex.org/I5023651"]}]}],"institutions":[],"countries_distinct_count":6,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5035461704"],"corresponding_institution_ids":["https://openalex.org/I183935753","https://openalex.org/I2801824472","https://openalex.org/I4405267356","https://openalex.org/I5023651"],"apc_list":{"value":11390,"currency":"USD","value_usd":11390},"apc_paid":null,"fwci":25.4529,"has_fulltext":true,"cited_by_count":270,"citation_normalized_percentile":{"value":0.99834446,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"27","issue":"4","first_page":"659","last_page":"667"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8842999935150146,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.8842999935150146,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.05290000140666962,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.04010000079870224,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oas1","display_name":"OAS1","score":0.9639999866485596},{"id":"https://openalex.org/keywords/covid-19-susceptibility","display_name":"COVID-19 susceptibility","score":0.8500000238418579},{"id":"https://openalex.org/keywords/covid-19-severity","display_name":"COVID-19 severity","score":0.9179999828338623},{"id":"https://openalex.org/keywords/circulating-proteins","display_name":"circulating proteins","score":0.9459999799728394},{"id":"https://openalex.org/keywords/plasma-biomarkers","display_name":"plasma biomarkers","score":0.6340000033378601},{"id":"https://openalex.org/keywords/mendelian-randomization","display_name":"Mendelian randomization","score":0.8669999837875366},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.8539999723434448},{"id":"https://openalex.org/keywords/covid-19-hospitalization","display_name":"COVID-19 hospitalization","score":0.8180000185966492},{"id":"https://openalex.org/keywords/covid-19-mortality","display_name":"COVID-19 mortality","score":0.953000009059906},{"id":"https://openalex.org/keywords/european-ancestry","display_name":"European ancestry","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5379019975662231},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.5159476399421692},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5104595422744751},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4422927796840668},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.43168994784355164},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33068519830703735}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012720","descriptor_name":"Severity of Illness Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015088","descriptor_name":"2',5'-Oligoadenylate Synthetase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015088","descriptor_name":"2',5'-Oligoadenylate Synthetase","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D040641","descriptor_name":"Quantitative Trait Loci","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053710","descriptor_name":"Interleukin-10 Receptor beta Subunit","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D057182","descriptor_name":"Mendelian Randomization Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059125","descriptor_name":"Neanderthals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41591-021-01281-1","doi":"https://doi.org/10.1038/s41591-021-01281-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41591-021-01281-1","pdf_url":"https://www.nature.com/articles/s41591-021-01281-1.pdf","source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},{"id":"doi:10.1101/2020.10.13.20212092","doi":"https://doi.org/10.1101/2020.10.13.20212092","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2020.10.13.20212092","pdf_url":null,"source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:33633408","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33633408","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature medicine","raw_type":"Journal Article"},{"id":"pmh:oai:www.repository.cam.ac.uk:1810/321610","doi":null,"is_oa":false,"landing_page_url":"https://www.repository.cam.ac.uk/handle/1810/321610","pdf_url":null,"source":{"id":"https://openalex.org/S4306401777","display_name":"Apollo (University of Cambridge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I241749","host_organization_name":"University of Cambridge","host_organization_lineage":["https://openalex.org/I241749"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"doi:10.17863/cam.68728","doi":"https://doi.org/10.17863/cam.68728","is_oa":true,"landing_page_url":"https://doi.org/10.17863/cam.68728","pdf_url":null,"source":{"id":"https://openalex.org/S7407050737","display_name":"Apollo","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1038/s41591-021-01281-1","doi":"https://doi.org/10.1038/s41591-021-01281-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41591-021-01281-1","pdf_url":"https://www.nature.com/articles/s41591-021-01281-1.pdf","source":{"id":"https://openalex.org/S203256638","display_name":"Nature Medicine","issn_l":"1078-8956","issn":["1078-8956","1546-170X","1744-7933"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1125910315","display_name":null,"funder_award_id":"2014-02569 and 2014-07606","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G2536127326","display_name":null,"funder_award_id":"KAW2020.0182","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G2975900969","display_name":null,"funder_award_id":"2020 \u2018","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3304509792","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G3778471351","display_name":null,"funder_award_id":"173203","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G4359907850","display_name":"Rx&D-HRF/CIHR Summer Research Awards in Medicine 2000-2001 (University of Toronto - 7 Students)","funder_award_id":"40951_1","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G4410375089","display_name":null,"funder_award_id":"KAW-2020-0182","funder_id":"https://openalex.org/F4320325677","funder_display_name":"Science for Life Laboratory"},{"id":"https://openalex.org/G4473141830","display_name":"Early immune predictors of sustained SARS-CoV-2 antibody responses after COVID-19 disease","funder_award_id":"173203_1","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G4645611456","display_name":null,"funder_award_id":"2020\u20100182","funder_id":"https://openalex.org/F4320325677","funder_display_name":"Science for Life Laboratory"},{"id":"https://openalex.org/G475627954","display_name":null,"funder_award_id":"110068-68-RGCV","funder_id":"https://openalex.org/F4320306342","funder_display_name":"amfAR, The Foundation for AIDS Research"},{"id":"https://openalex.org/G5514976981","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6122222817","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6427258204","display_name":"Acute kidney injury - mechanisms and novel therapeutic targets in large animal models","funder_award_id":"2014-02569","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"},{"id":"https://openalex.org/G6975540971","display_name":"\u591a\u65bd\u8a2d\u30b3\u30db\u30fc\u30c8\u3092\u7528\u3044\u305f\u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\u306b\u304a\u3051\u308b\u65b0\u898f\u907a\u4f1d\u5b50\u591a\u578b\u306e\u540c\u5b9a","funder_award_id":"19J21080","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7815315804","display_name":null,"funder_award_id":"365825","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"},{"id":"https://openalex.org/G8415457339","display_name":null,"funder_award_id":"COVID-19","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G844907251","display_name":"Acute kidney injury - mechanisms and novel therapeutic targets in large animal models","funder_award_id":"2014-07606","funder_id":"https://openalex.org/F4320322581","funder_display_name":"Vetenskapsr\u00e5det"}],"funders":[{"id":"https://openalex.org/F4320306342","display_name":"amfAR, The Foundation for AIDS Research","ror":"https://ror.org/02jesmk44"},{"id":"https://openalex.org/F4320310638","display_name":"McGill University","ror":"https://ror.org/01pxwe438"},{"id":"https://openalex.org/F4320312568","display_name":"Public Health Agency of Canada","ror":"https://ror.org/023xf2a37"},{"id":"https://openalex.org/F4320314000","display_name":"Compute Canada","ror":"https://ror.org/03ty8yr27"},{"id":"https://openalex.org/F4320314794","display_name":"McGill University Health Centre","ror":"https://ror.org/04cpxjv19"},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320853","display_name":"Public Health Agency","ror":"https://ror.org/03ek62e72"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320322842","display_name":"Jewish General Hospital","ror":"https://ror.org/056jjra10"},{"id":"https://openalex.org/F4320325677","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334618","display_name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","ror":"https://ror.org/02eqrsj93"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3132221372.pdf","grobid_xml":"https://content.openalex.org/works/W3132221372.grobid-xml"},"referenced_works_count":83,"referenced_works":["https://openalex.org/W1201901877","https://openalex.org/W1500943849","https://openalex.org/W1519544099","https://openalex.org/W1593256488","https://openalex.org/W1967105697","https://openalex.org/W1978329469","https://openalex.org/W1995296637","https://openalex.org/W2000167382","https://openalex.org/W2014298751","https://openalex.org/W2038686775","https://openalex.org/W2046289497","https://openalex.org/W2049898530","https://openalex.org/W2068824485","https://openalex.org/W2073836327","https://openalex.org/W2099085143","https://openalex.org/W2099336504","https://openalex.org/W2099906640","https://openalex.org/W2101039718","https://openalex.org/W2104549677","https://openalex.org/W2106036991","https://openalex.org/W2108830583","https://openalex.org/W2113306639","https://openalex.org/W2118822739","https://openalex.org/W2125238675","https://openalex.org/W2129499324","https://openalex.org/W2133402546","https://openalex.org/W2153222616","https://openalex.org/W2159723633","https://openalex.org/W2164852591","https://openalex.org/W2273395099","https://openalex.org/W2280924794","https://openalex.org/W2334973813","https://openalex.org/W2398690791","https://openalex.org/W2466011795","https://openalex.org/W2520048741","https://openalex.org/W2566116513","https://openalex.org/W2579779633","https://openalex.org/W2605261164","https://openalex.org/W2622444804","https://openalex.org/W2721556819","https://openalex.org/W2761275051","https://openalex.org/W2762876887","https://openalex.org/W2767195935","https://openalex.org/W2771966708","https://openalex.org/W2774883395","https://openalex.org/W2805712258","https://openalex.org/W2805983714","https://openalex.org/W2885870007","https://openalex.org/W2886245587","https://openalex.org/W2923177995","https://openalex.org/W2943309532","https://openalex.org/W2943766116","https://openalex.org/W2952264760","https://openalex.org/W2952443114","https://openalex.org/W2977265011","https://openalex.org/W3004080087","https://openalex.org/W3027630905","https://openalex.org/W3028410545","https://openalex.org/W3040751560","https://openalex.org/W3042270788","https://openalex.org/W3044118599","https://openalex.org/W3082355253","https://openalex.org/W3083496521","https://openalex.org/W3087825238","https://openalex.org/W3087862874","https://openalex.org/W3090928025","https://openalex.org/W3090929175","https://openalex.org/W3092245962","https://openalex.org/W3092323724","https://openalex.org/W3093084901","https://openalex.org/W3103598365","https://openalex.org/W3104457017","https://openalex.org/W3110466220","https://openalex.org/W3111431752","https://openalex.org/W3111898055","https://openalex.org/W3112105690","https://openalex.org/W3112865260","https://openalex.org/W3127349317","https://openalex.org/W3133087446","https://openalex.org/W3133859624","https://openalex.org/W3139784018","https://openalex.org/W3159431441","https://openalex.org/W4229484941"],"related_works":["https://openalex.org/W4285391095","https://openalex.org/W4285047477","https://openalex.org/W4283779419","https://openalex.org/W4395462663","https://openalex.org/W4415280122","https://openalex.org/W4386054883","https://openalex.org/W4226413939","https://openalex.org/W7140303240","https://openalex.org/W4221103317","https://openalex.org/W3149737383"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":34},{"year":2025,"cited_by_count":28},{"year":2024,"cited_by_count":47},{"year":2023,"cited_by_count":57},{"year":2022,"cited_by_count":68},{"year":2021,"cited_by_count":36}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-03-01T00:00:00"}
