{"id":"https://openalex.org/W3132013952","doi":"https://doi.org/10.3892/etm.2021.9803","title":"Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/\u03b2\u2011catenin signaling pathway","display_name":"Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/\u03b2\u2011catenin signaling pathway","publication_year":2021,"publication_date":"2021-02-19","ids":{"openalex":"https://openalex.org/W3132013952","doi":"https://doi.org/10.3892/etm.2021.9803","mag":"3132013952","pmid":"https://pubmed.ncbi.nlm.nih.gov/33732345","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7903451"},"language":"en","primary_location":{"id":"doi:10.3892/etm.2021.9803","doi":"https://doi.org/10.3892/etm.2021.9803","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2021.9803","pdf_url":"https://www.spandidos-publications.com/10.3892/etm.2021.9803/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.spandidos-publications.com/10.3892/etm.2021.9803/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006055761","display_name":"Yun Yi","orcid":"https://orcid.org/0000-0002-6059-6331","observed_orcids":["https://orcid.org/0000-0002-6059-6331"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210097309","display_name":"Jiangxi Provincial Cancer Hospital","ror":"https://ror.org/00v8g0168","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097309"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Yi","raw_affiliation_strings":["Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210097309"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bing Liao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Liao","raw_affiliation_strings":["Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330000, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330000, P.R. China","institution_ids":["https://openalex.org/I4210108480"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113443691","display_name":"Ziwen Zheng","orcid":"https://orcid.org/0009-0008-6346-5995","observed_orcids":["https://orcid.org/0009-0008-6346-5995"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210097309","display_name":"Jiangxi Provincial Cancer Hospital","ror":"https://ror.org/00v8g0168","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097309"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziwen Zheng","raw_affiliation_strings":["Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210097309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068717952","display_name":"Xiaorong Yang","orcid":"https://orcid.org/0000-0001-9463-8811","observed_orcids":["https://orcid.org/0000-0001-9463-8811"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210097309","display_name":"Jiangxi Provincial Cancer Hospital","ror":"https://ror.org/00v8g0168","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097309"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaorong Yang","raw_affiliation_strings":["Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210097309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057933211","display_name":"Yunsheng Yang","orcid":"https://orcid.org/0000-0003-0361-7674","observed_orcids":["https://orcid.org/0000-0003-0361-7674","https://orcid.org/0000-0001-7032-3540"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210097309","display_name":"Jiangxi Provincial Cancer Hospital","ror":"https://ror.org/00v8g0168","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097309"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunsheng Yang","raw_affiliation_strings":["Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210097309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101892508","display_name":"Yanfang Zhou","orcid":"https://orcid.org/0000-0003-3371-6702","observed_orcids":["https://orcid.org/0000-0003-3371-6702"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210097309","display_name":"Jiangxi Provincial Cancer Hospital","ror":"https://ror.org/00v8g0168","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097309"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanfang Zhou","raw_affiliation_strings":["Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210097309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103117632","display_name":"Buzhen Tan","orcid":"https://orcid.org/0000-0002-2565-1083","observed_orcids":["https://orcid.org/0000-0002-2565-1083","https://orcid.org/0000-0003-1795-2748"]},"institutions":[{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Buzhen Tan","raw_affiliation_strings":["Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330000, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330000, P.R. China","institution_ids":["https://openalex.org/I4210108480"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026047801","display_name":"Xinfeng Yang","orcid":"https://orcid.org/0009-0005-2059-7267","observed_orcids":["https://orcid.org/0009-0005-2059-7267"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210097309","display_name":"Jiangxi Provincial Cancer Hospital","ror":"https://ror.org/00v8g0168","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097309"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinfeng Yang","raw_affiliation_strings":["Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecological Oncology, Cancer Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330029, P.R. China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210097309"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103117632"],"corresponding_institution_ids":["https://openalex.org/I4210108480"],"apc_list":null,"apc_paid":null,"fwci":0.5606,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.56702741,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"21","issue":"4","first_page":"372","last_page":"372"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.7890999913215637,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.7890999913215637,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.14509999752044678,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.02280000038444996,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dec1","display_name":"DEC1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.9559999704360962},{"id":"https://openalex.org/keywords/wnt-beta-catenin-signaling","display_name":"Wnt/\u03b2-catenin signaling","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8610000014305115},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.8840000033378601},{"id":"https://openalex.org/keywords/cell-invasion","display_name":"cell invasion","score":0.8769999742507935},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":1.0},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7839999794960022},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.4440000057220459},{"id":"https://openalex.org/keywords/skov-3-cells","display_name":"SKOV3 cells","score":0.75},{"id":"https://openalex.org/keywords/ovcar-3-cells","display_name":"OVCAR-3 cells","score":1.0}],"concepts":[{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.9233202338218689},{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.7082393765449524},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6440633535385132},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5574281811714172},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5166419148445129},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.5140112638473511},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.46778640151023865},{"id":"https://openalex.org/C2781018059","wikidata":"https://www.wikidata.org/wiki/Q207609","display_name":"Oncogene","level":4,"score":0.46528947353363037},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4350917339324951},{"id":"https://openalex.org/C76419328","wikidata":"https://www.wikidata.org/wiki/Q74419","display_name":"Epithelial\u2013mesenchymal transition","level":4,"score":0.4322246313095093},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.3861422836780548},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.336497962474823},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0600147545337677},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0411546528339386}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3892/etm.2021.9803","doi":"https://doi.org/10.3892/etm.2021.9803","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2021.9803","pdf_url":"https://www.spandidos-publications.com/10.3892/etm.2021.9803/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},{"id":"pmid:33732345","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33732345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and therapeutic medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7903451","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7903451/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exp Ther Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3892/etm.2021.9803","doi":"https://doi.org/10.3892/etm.2021.9803","is_oa":true,"landing_page_url":"https://doi.org/10.3892/etm.2021.9803","pdf_url":"https://www.spandidos-publications.com/10.3892/etm.2021.9803/download","source":{"id":"https://openalex.org/S151424340","display_name":"Experimental and Therapeutic Medicine","issn_l":"1792-0981","issn":["1792-0981","1792-1015"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320412","host_organization_name":"Spandidos Publishing","host_organization_lineage":["https://openalex.org/P4310320412"],"host_organization_lineage_names":["Spandidos Publishing"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental and Therapeutic Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3132013952.pdf","grobid_xml":"https://content.openalex.org/works/W3132013952.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W85215810","https://openalex.org/W1965407621","https://openalex.org/W1979831342","https://openalex.org/W1986424797","https://openalex.org/W1987367854","https://openalex.org/W1989768090","https://openalex.org/W2002827531","https://openalex.org/W2014978200","https://openalex.org/W2018488292","https://openalex.org/W2049136164","https://openalex.org/W2060648544","https://openalex.org/W2079466805","https://openalex.org/W2089517473","https://openalex.org/W2090354699","https://openalex.org/W2090952321","https://openalex.org/W2107277218","https://openalex.org/W2112713769","https://openalex.org/W2124384402","https://openalex.org/W2133781545","https://openalex.org/W2139745007","https://openalex.org/W2171279050","https://openalex.org/W2210270878","https://openalex.org/W2276190994","https://openalex.org/W2463928251","https://openalex.org/W2515153451","https://openalex.org/W2557243447","https://openalex.org/W2560512460","https://openalex.org/W2574659094","https://openalex.org/W2600254598","https://openalex.org/W2604915087","https://openalex.org/W2606506757","https://openalex.org/W2735265951","https://openalex.org/W2739083812","https://openalex.org/W2743243574","https://openalex.org/W2747277101","https://openalex.org/W2747888156","https://openalex.org/W2770300603","https://openalex.org/W2773387349","https://openalex.org/W2780276291","https://openalex.org/W2790923672","https://openalex.org/W2791440530","https://openalex.org/W2800731106","https://openalex.org/W2801370985","https://openalex.org/W2807649309","https://openalex.org/W2890435361","https://openalex.org/W2900900388","https://openalex.org/W2911188335","https://openalex.org/W2915478882","https://openalex.org/W2963364055","https://openalex.org/W2964278761","https://openalex.org/W2965074415","https://openalex.org/W2966167893","https://openalex.org/W2971462397","https://openalex.org/W2972121144","https://openalex.org/W2975844090","https://openalex.org/W2979024634","https://openalex.org/W4283313052"],"related_works":["https://openalex.org/W4210910122","https://openalex.org/W2747277101","https://openalex.org/W2759490850","https://openalex.org/W3024487962","https://openalex.org/W2339692589","https://openalex.org/W2520723186","https://openalex.org/W2317164901","https://openalex.org/W3214472995","https://openalex.org/W4415684912","https://openalex.org/W2910841609"],"abstract_inverted_index":{"DEC1":[0,34,54,62,84,99,111,132,150,165,184],"has":[1],"been":[2],"reported":[3],"to":[4,45],"regulate":[5],"the":[6,19,27,47,89,118,154,158,179],"expression":[7,48,82,119],"of":[8,23,33,51,53,83,91,98,120,131,141,164,190,201],"multiple":[9],"target":[10,196],"genes,":[11],"participate":[12,186],"in":[13,35,55,66,103,123,174,187],"cell":[14,70,135],"differentiation,":[15],"apoptosis,":[16],"aging":[17],"and":[18,21,30,49,69,78,80,105,116,137,169,171,192,199],"development":[20],"progression":[22,189],"numerous":[24],"tumors,":[25],"but":[26],"detailed":[28],"effects":[29],"possible":[31],"mechanisms":[32],"ovarian":[36],"cancer":[37],"(OC)":[38],"remain":[39],"unknown.":[40],"The":[41,57,126],"present":[42,58],"study":[43],"aimed":[44],"investigate":[46],"mechanism":[50],"function":[52],"OC.":[56,94,202],"results":[59,127,160],"demonstrated":[60],"that":[61,129,149,162],"was":[63,85,146],"highly":[64],"expressed":[65],"OC":[67,124,134,175],"tissues":[68],"lines":[71],"using":[72],"reverse":[73],"transcription-quantitative":[74],"PCR,":[75],"western":[76],"blotting":[77],"immunohistochemistry,":[79],"high":[81],"negatively":[86],"associated":[87],"with":[88,93,109],"prognosis":[90],"patients":[92],"In":[95],"addition,":[96],"knockdown":[97,112,130,151,163],"significantly":[100,152],"inhibited":[101,133,153,166],"proliferation":[102],"SKOV3":[104],"OVCAR3":[106],"cells":[107,176],"compared":[108],"control.":[110],"also":[113,147],"induced":[114,172],"apoptosis":[115,173],"increased":[117],"apoptosis-related":[121],"proteins":[122],"cells.":[125],"suggested":[128],"migration":[136,168],"invasion":[138],"via":[139,177],"regulation":[140],"epithelial-mesenchymal":[142],"transition-related":[143],"protein.":[144],"It":[145],"found":[148],"Wnt/\u03b2-catenin":[155,180],"pathway.":[156,182],"Collectively,":[157],"current":[159],"indicated":[161],"proliferation,":[167],"invasion,":[170],"modulating":[178],"signaling":[181],"Thus,":[183],"may":[185,193],"malignant":[188],"OC,":[191],"be":[194],"a":[195],"for":[197],"treatment":[198],"diagnosis":[200]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-03-01T00:00:00"}