{"id":"https://openalex.org/W3131842571","doi":"https://doi.org/10.3390/cancers13040930","title":"The Revolutionary Roads to Study Cell\u2013Cell Interactions in 3D In Vitro Pancreatic Cancer Models","display_name":"The Revolutionary Roads to Study Cell\u2013Cell Interactions in 3D In Vitro Pancreatic Cancer Models","publication_year":2021,"publication_date":"2021-02-23","ids":{"openalex":"https://openalex.org/W3131842571","doi":"https://doi.org/10.3390/cancers13040930","mag":"3131842571","pmid":"https://pubmed.ncbi.nlm.nih.gov/33672435","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7926501"},"language":"en","primary_location":{"id":"doi:10.3390/cancers13040930","doi":"https://doi.org/10.3390/cancers13040930","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers13040930","pdf_url":"https://www.mdpi.com/2072-6694/13/4/930/pdf?version=1614329078","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2072-6694/13/4/930/pdf?version=1614329078","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058804707","display_name":"Donatella Delle Cave","orcid":"https://orcid.org/0000-0002-4019-2778","observed_orcids":["https://orcid.org/0000-0002-4019-2778"]},"institutions":[{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Donatella Delle Cave","raw_affiliation_strings":["Institute of Genetics and Biophysics \u201cA. Buzzati-Traverso\u201d, National Research Council (CNR-IGB), Via Pietro Castellino 111, 80131 Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0002-4019-2778","affiliations":[{"raw_affiliation_string":"Institute of Genetics and Biophysics \u201cA. Buzzati-Traverso\u201d, National Research Council (CNR-IGB), Via Pietro Castellino 111, 80131 Naples, Italy","institution_ids":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022575679","display_name":"Riccardo Rizzo","orcid":"https://orcid.org/0000-0002-5716-9195","observed_orcids":["https://orcid.org/0000-0002-5716-9195"]},"institutions":[{"id":"https://openalex.org/I4210091015","display_name":"Istituto di Nanotecnologia","ror":"https://ror.org/00bc51d88","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210091015","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Riccardo Rizzo","raw_affiliation_strings":["Institute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, via Monteroni, 73100 Lecce, Italy"],"raw_orcid":"https://orcid.org/0000-0002-5716-9195","affiliations":[{"raw_affiliation_string":"Institute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, via Monteroni, 73100 Lecce, Italy","institution_ids":["https://openalex.org/I4210091015","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031406092","display_name":"Bruno S\u00e1inz","orcid":"https://orcid.org/0000-0003-4829-7651","observed_orcids":["https://orcid.org/0000-0003-4829-7651"]},"institutions":[{"id":"https://openalex.org/I134820265","display_name":"Consejo Superior de Investigaciones Cient\u00edficas","ror":"https://ror.org/02gfc7t72","country_code":"ES","type":"government","lineage":["https://openalex.org/I134820265"]},{"id":"https://openalex.org/I4210091816","display_name":"Instituto de Investigaciones Biom\u00e9dicas Sols-Morreale","ror":"https://ror.org/00ha1f767","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I4210091816","https://openalex.org/I63634437"]},{"id":"https://openalex.org/I4210127475","display_name":"Instituto Ram\u00f3n y Cajal de Investigaci\u00f3n Sanitaria","ror":"https://ror.org/03fftr154","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210127475"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Bruno Sainz","raw_affiliation_strings":["Department of Cancer Biology, Instituto de Investigaciones Biomedicas \u201cAlberto Sols\u201d (IIBM), CSIC-UAM, 28029 Madrid, Spain","Spain and Chronic Diseases and Cancer, Area 3-Instituto Ramon y Cajal de Investigacion Sanitaria (IRYCIS), 28029 Madrid, Spain"],"raw_orcid":"https://orcid.org/0000-0003-4829-7651","affiliations":[{"raw_affiliation_string":"Department of Cancer Biology, Instituto de Investigaciones Biomedicas \u201cAlberto Sols\u201d (IIBM), CSIC-UAM, 28029 Madrid, Spain","institution_ids":["https://openalex.org/I134820265","https://openalex.org/I4210091816"]},{"raw_affiliation_string":"Spain and Chronic Diseases and Cancer, Area 3-Instituto Ramon y Cajal de Investigacion Sanitaria (IRYCIS), 28029 Madrid, Spain","institution_ids":["https://openalex.org/I4210127475"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036753801","display_name":"Giuseppe Gigli","orcid":"https://orcid.org/0000-0002-2583-5747","observed_orcids":["https://orcid.org/0000-0002-2583-5747"]},"institutions":[{"id":"https://openalex.org/I142910587","display_name":"University of Salento","ror":"https://ror.org/03fc1k060","country_code":"IT","type":"education","lineage":["https://openalex.org/I142910587"]},{"id":"https://openalex.org/I4210091015","display_name":"Istituto di Nanotecnologia","ror":"https://ror.org/00bc51d88","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210091015","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Gigli","raw_affiliation_strings":["Department of Mathematics and Physics \u201cEnnio De Giorgi\u201d, University of Salento, via Arnesano, 73100 Lecce, Italy","Institute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, via Monteroni, 73100 Lecce, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematics and Physics \u201cEnnio De Giorgi\u201d, University of Salento, via Arnesano, 73100 Lecce, Italy","institution_ids":["https://openalex.org/I142910587"]},{"raw_affiliation_string":"Institute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, via Monteroni, 73100 Lecce, Italy","institution_ids":["https://openalex.org/I4210091015","https://openalex.org/I4210155236"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087247790","display_name":"Loretta L. del Mercato","orcid":"https://orcid.org/0000-0001-9733-7088","observed_orcids":["https://orcid.org/0000-0001-9733-7088"]},"institutions":[{"id":"https://openalex.org/I4210091015","display_name":"Istituto di Nanotecnologia","ror":"https://ror.org/00bc51d88","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210091015","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Loretta L. del Mercato","raw_affiliation_strings":["Institute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, via Monteroni, 73100 Lecce, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9733-7088","affiliations":[{"raw_affiliation_string":"Institute of Nanotechnology, National Research Council (CNR-NANOTEC), c/o Campus Ecotekne, via Monteroni, 73100 Lecce, Italy","institution_ids":["https://openalex.org/I4210091015","https://openalex.org/I4210155236"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043067889","display_name":"Enza Lonardo","orcid":"https://orcid.org/0000-0001-6654-1043","observed_orcids":["https://orcid.org/0000-0001-6654-1043","https://orcid.org/0000-0002-9227-3772"]},"institutions":[{"id":"https://openalex.org/I4210137461","display_name":"Institute of Genetics and Biophysics","ror":"https://ror.org/04hadk112","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Enza Lonardo","raw_affiliation_strings":["Institute of Genetics and Biophysics \u201cA. Buzzati-Traverso\u201d, National Research Council (CNR-IGB), Via Pietro Castellino 111, 80131 Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics and Biophysics \u201cA. Buzzati-Traverso\u201d, National Research Council (CNR-IGB), Via Pietro Castellino 111, 80131 Naples, Italy","institution_ids":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5043067889"],"corresponding_institution_ids":["https://openalex.org/I4210137461","https://openalex.org/I4210155236"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2376},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2376},"fwci":0.7801,"has_fulltext":true,"cited_by_count":47,"citation_normalized_percentile":{"value":0.60459275,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"13","issue":"4","first_page":"930","last_page":"930"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.5824999809265137,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.5824999809265137,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.37450000643730164,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.012500000186264515,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":1.0},{"id":"https://openalex.org/keywords/cell-cell-interactions","display_name":"cell-cell interactions","score":0.8669999837875366},{"id":"https://openalex.org/keywords/3d-in-vitro-model","display_name":"3D in vitro model","score":0.8379999995231628},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.777999997138977},{"id":"https://openalex.org/keywords/anticancer-drug-discovery","display_name":"anticancer drug discovery","score":0.9700000286102295},{"id":"https://openalex.org/keywords/drug-screening","display_name":"drug screening","score":0.5320000052452087},{"id":"https://openalex.org/keywords/anticancer-drug-development","display_name":"anticancer drug development","score":0.3449999988079071}],"concepts":[{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.8508799076080322},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.6365082263946533},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.6201061606407166},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5613272786140442},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5056283473968506},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.460573673248291},{"id":"https://openalex.org/C3018146709","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Anticancer drug","level":3,"score":0.42076486349105835},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.4176703989505768},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.393018901348114},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3730517327785492},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.34725886583328247},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.34600698947906494},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2733788788318634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.21208041906356812},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.21203964948654175},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.10458433628082275}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/cancers13040930","doi":"https://doi.org/10.3390/cancers13040930","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers13040930","pdf_url":"https://www.mdpi.com/2072-6694/13/4/930/pdf?version=1614329078","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},{"id":"pmid:33672435","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33672435","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7926501","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7926501/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:7f4d30e6d386400eadaedd39b6a9b18d","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7f4d30e6d386400eadaedd39b6a9b18d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancers, Vol 13, Iss 930, p 930 (2021)","raw_type":"article"},{"id":"pmh:oai:iris.unisalento.it:11587/467872","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11587/467872","pdf_url":null,"source":{"id":"https://openalex.org/S7407055257","display_name":"AIRUS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/cancers13040930","doi":"https://doi.org/10.3390/cancers13040930","is_oa":true,"landing_page_url":"https://doi.org/10.3390/cancers13040930","pdf_url":"https://www.mdpi.com/2072-6694/13/4/930/pdf?version=1614329078","source":{"id":"https://openalex.org/S168415115","display_name":"Cancers","issn_l":"2072-6694","issn":["2072-6694"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancers","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1885775645","display_name":null,"funder_award_id":"759959","funder_id":"https://openalex.org/F4320334678","funder_display_name":"European Research Council"},{"id":"https://openalex.org/G8064526221","display_name":null,"funder_award_id":"20206","funder_id":"https://openalex.org/F4320323054","funder_display_name":"Associazione Italiana per la Ricerca sul Cancro"}],"funders":[{"id":"https://openalex.org/F4320323054","display_name":"Associazione Italiana per la Ricerca sul Cancro","ror":"https://ror.org/02g2x7380"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3131842571.pdf","grobid_xml":"https://content.openalex.org/works/W3131842571.grobid-xml"},"referenced_works_count":119,"referenced_works":["https://openalex.org/W641954586","https://openalex.org/W904057427","https://openalex.org/W1571509546","https://openalex.org/W1837090400","https://openalex.org/W1964937406","https://openalex.org/W1968812902","https://openalex.org/W1970238011","https://openalex.org/W1995874183","https://openalex.org/W1996912024","https://openalex.org/W1999459866","https://openalex.org/W2010916968","https://openalex.org/W2011807945","https://openalex.org/W2020609902","https://openalex.org/W2033474014","https://openalex.org/W2037884629","https://openalex.org/W2045810780","https://openalex.org/W2057280155","https://openalex.org/W2063551078","https://openalex.org/W2065479737","https://openalex.org/W2068060534","https://openalex.org/W2071235666","https://openalex.org/W2079418758","https://openalex.org/W2088110734","https://openalex.org/W2094314563","https://openalex.org/W2111895881","https://openalex.org/W2117613086","https://openalex.org/W2118997868","https://openalex.org/W2120772428","https://openalex.org/W2121011070","https://openalex.org/W2151253787","https://openalex.org/W2203385592","https://openalex.org/W2262915357","https://openalex.org/W2272762748","https://openalex.org/W2319156699","https://openalex.org/W2373958043","https://openalex.org/W2414892650","https://openalex.org/W2416037803","https://openalex.org/W2471786809","https://openalex.org/W2484140440","https://openalex.org/W2518520946","https://openalex.org/W2558115760","https://openalex.org/W2560322684","https://openalex.org/W2590390825","https://openalex.org/W2608386102","https://openalex.org/W2624733560","https://openalex.org/W2737053924","https://openalex.org/W2740653964","https://openalex.org/W2746455523","https://openalex.org/W2758901376","https://openalex.org/W2765483150","https://openalex.org/W2768711535","https://openalex.org/W2768923525","https://openalex.org/W2770810616","https://openalex.org/W2772996285","https://openalex.org/W2775638497","https://openalex.org/W2783122422","https://openalex.org/W2791017844","https://openalex.org/W2795248085","https://openalex.org/W2802371551","https://openalex.org/W2804265459","https://openalex.org/W2805627081","https://openalex.org/W2805755268","https://openalex.org/W2806859060","https://openalex.org/W2807088563","https://openalex.org/W2883584659","https://openalex.org/W2890158083","https://openalex.org/W2890360170","https://openalex.org/W2898024988","https://openalex.org/W2898386214","https://openalex.org/W2899358783","https://openalex.org/W2901391118","https://openalex.org/W2909317697","https://openalex.org/W2909528400","https://openalex.org/W2909729333","https://openalex.org/W2911819518","https://openalex.org/W2913836031","https://openalex.org/W2919118480","https://openalex.org/W2920686366","https://openalex.org/W2943595607","https://openalex.org/W2944310018","https://openalex.org/W2944434139","https://openalex.org/W2950277848","https://openalex.org/W2952591625","https://openalex.org/W2953663647","https://openalex.org/W2967345928","https://openalex.org/W2970097127","https://openalex.org/W2974601160","https://openalex.org/W2984284890","https://openalex.org/W2985641540","https://openalex.org/W2991564522","https://openalex.org/W2993993303","https://openalex.org/W3001200992","https://openalex.org/W3002455262","https://openalex.org/W3003341929","https://openalex.org/W3004857352","https://openalex.org/W3006093334","https://openalex.org/W3008247200","https://openalex.org/W3008636104","https://openalex.org/W3010019840","https://openalex.org/W3012570087","https://openalex.org/W3016071795","https://openalex.org/W3016181576","https://openalex.org/W3023998523","https://openalex.org/W3026717936","https://openalex.org/W3028096043","https://openalex.org/W3029024305","https://openalex.org/W3035635204","https://openalex.org/W3036068841","https://openalex.org/W3037120385","https://openalex.org/W3041351854","https://openalex.org/W3081146678","https://openalex.org/W3082407875","https://openalex.org/W3087102249","https://openalex.org/W3089526215","https://openalex.org/W3092854160","https://openalex.org/W4232177511","https://openalex.org/W4240395330","https://openalex.org/W4251343507","https://openalex.org/W4255696946"],"related_works":["https://openalex.org/W2784763866","https://openalex.org/W2511487690","https://openalex.org/W4306923032","https://openalex.org/W3016071795","https://openalex.org/W3141757693","https://openalex.org/W3203469850","https://openalex.org/W3083620108","https://openalex.org/W4390755248","https://openalex.org/W2030945442","https://openalex.org/W7131322554"],"abstract_inverted_index":{"Pancreatic":[0],"cancer,":[1,87],"the":[2,15,32,52,64],"fourth":[3],"most":[4],"common":[5],"cancer":[6],"worldwide,":[7],"shows":[8],"a":[9],"highly":[10],"unsuccessful":[11],"therapeutic":[12,24],"response.":[13],"In":[14,73],"last":[16],"10":[17],"years,":[18],"neither":[19],"important":[20],"advancements":[21],"nor":[22],"new":[23,36],"strategies":[25],"have":[26],"significantly":[27],"impacted":[28],"patient":[29],"survival,":[30],"highlighting":[31],"need":[33],"to":[34,92],"pursue":[35],"avenues":[37],"for":[38,81],"drug":[39,83],"development":[40],"discovery":[41,84],"and":[42],"design.":[43],"Advanced":[44],"cellular":[45],"models,":[46],"resembling":[47],"as":[48,50],"much":[49],"possible":[51],"original":[53],"in":[54,62,70,85],"vivo":[55],"tumor":[56],"environment,":[57],"may":[58],"be":[59],"more":[60],"successful":[61],"predicting":[63],"efficacy":[65],"of":[66],"future":[67],"anti-cancer":[68],"candidates":[69],"clinical":[71],"trials.":[72],"this":[74],"review,":[75],"we":[76],"discuss":[77],"novel":[78],"bioengineered":[79],"platforms":[80],"anticancer":[82],"pancreatic":[86],"from":[88],"traditional":[89],"two-dimensional":[90],"models":[91],"innovative":[93],"three-dimensional":[94],"ones.":[95]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":6}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2021-03-01T00:00:00"}