{"id":"https://openalex.org/W3131740728","doi":"https://doi.org/10.1080/10643389.2021.1886556","title":"Prenatal and postnatal transfer of perfluoroalkyl substances from mothers to their offspring","display_name":"Prenatal and postnatal transfer of perfluoroalkyl substances from mothers to their offspring","publication_year":2021,"publication_date":"2021-02-20","ids":{"openalex":"https://openalex.org/W3131740728","doi":"https://doi.org/10.1080/10643389.2021.1886556","mag":"3131740728"},"language":"en","primary_location":{"id":"doi:10.1080/10643389.2021.1886556","doi":"https://doi.org/10.1080/10643389.2021.1886556","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10643389.2021.1886556","pdf_url":null,"source":{"id":"https://openalex.org/S207935976","display_name":"Critical Reviews in Environmental Science and Technology","issn_l":"1064-3389","issn":["1064-3389","1547-6537"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Reviews in Environmental Science and Technology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073884147","display_name":"Yingxue Liu","orcid":"https://orcid.org/0009-0003-2738-0234","observed_orcids":["https://orcid.org/0009-0003-2738-0234"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingxue Liu","raw_affiliation_strings":["MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102884729","display_name":"An Li","orcid":"https://orcid.org/0000-0002-8476-8783","observed_orcids":["https://orcid.org/0000-0002-8476-8783"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"An Li","raw_affiliation_strings":["School of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA"],"raw_orcid":"https://orcid.org/0000-0002-8476-8783","affiliations":[{"raw_affiliation_string":"School of Public Health, University of Illinois at Chicago, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qi An","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi An","raw_affiliation_strings":["MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100739233","display_name":"Kai Liu","orcid":"https://orcid.org/0000-0002-5152-0706","observed_orcids":["https://orcid.org/0000-0002-5152-0706"]},"institutions":[{"id":"https://openalex.org/I3133055985","display_name":"Westlake University","ror":"https://ror.org/05hfa4n20","country_code":"CN","type":"education","lineage":["https://openalex.org/I3133055985"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Liu","raw_affiliation_strings":["Division of Environmental and Resource, College of Engineering, Westlake University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Environmental and Resource, College of Engineering, Westlake University, Hangzhou, China","institution_ids":["https://openalex.org/I3133055985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113582628","display_name":"Ping Zheng","orcid":"https://orcid.org/0000-0001-8101-2713","observed_orcids":["https://orcid.org/0000-0001-8101-2713"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Zheng","raw_affiliation_strings":["MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022251840","display_name":"Shanshan Yin","orcid":"https://orcid.org/0000-0001-8859-9852","observed_orcids":["https://orcid.org/0000-0001-8859-9852"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanshan Yin","raw_affiliation_strings":["MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100358868","display_name":"Weiping Liu","orcid":"https://orcid.org/0000-0002-1173-892X","observed_orcids":["https://orcid.org/0000-0002-1173-892X"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weiping Liu","raw_affiliation_strings":["MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-1173-892X","affiliations":[{"raw_affiliation_string":"MOE Key Laboratory of Environmental Remediation and Ecosystem Health, Institute of Environmental Health, Zhejiang University, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100358868"],"corresponding_institution_ids":["https://openalex.org/I76130692"],"apc_list":null,"apc_paid":null,"fwci":2.7359,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.90588815,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"52","issue":"14","first_page":"2510","last_page":"2537"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11869","display_name":"Per- and polyfluoroalkyl substances research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11869","display_name":"Per- and polyfluoroalkyl substances research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10947","display_name":"Fluorine in Organic Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/per-and-polyfluoroalkyl-substances","display_name":"per- and polyfluoroalkyl substances","score":0.9660000205039978},{"id":"https://openalex.org/keywords/pfas","display_name":"PFAS","score":0.7329999804496765},{"id":"https://openalex.org/keywords/transplacental-transfer","display_name":"transplacental transfer","score":0.9380000233650208},{"id":"https://openalex.org/keywords/breastfeeding","display_name":"breastfeeding","score":0.9390000104904175},{"id":"https://openalex.org/keywords/prenatal-exposure","display_name":"prenatal exposure","score":0.6179999709129333},{"id":"https://openalex.org/keywords/infant-exposure","display_name":"infant exposure","score":0.9480000138282776},{"id":"https://openalex.org/keywords/reference-dose","display_name":"reference dose","score":0.5479999780654907},{"id":"https://openalex.org/keywords/enantioselectivity","display_name":"enantioselectivity","score":0.8889999985694885},{"id":"https://openalex.org/keywords/alkyl-chain-length","display_name":"alkyl chain length","score":0.6769999861717224}],"concepts":[{"id":"https://openalex.org/C2779906218","wikidata":"https://www.wikidata.org/wiki/Q7834818","display_name":"Transplacental","level":5,"score":0.8955515623092651},{"id":"https://openalex.org/C2776283161","wikidata":"https://www.wikidata.org/wiki/Q174876","display_name":"Breastfeeding","level":2,"score":0.7069172859191895},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.7061876654624939},{"id":"https://openalex.org/C2775871700","wikidata":"https://www.wikidata.org/wiki/Q22728","display_name":"Breast milk","level":2,"score":0.5928685069084167},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.507072925567627},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.49653321504592896},{"id":"https://openalex.org/C3020294031","wikidata":"https://www.wikidata.org/wiki/Q174876","display_name":"Breast feeding","level":2,"score":0.47839224338531494},{"id":"https://openalex.org/C184151982","wikidata":"https://www.wikidata.org/wiki/Q7834236","display_name":"Transgenerational epigenetics","level":4,"score":0.4737333059310913},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.4645998179912567},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.46014153957366943},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.43213149905204773},{"id":"https://openalex.org/C2776659692","wikidata":"https://www.wikidata.org/wiki/Q719426","display_name":"Lactation","level":3,"score":0.4194115400314331},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.34887585043907166},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.33473557233810425},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.31368765234947205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2251107394695282},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09734421968460083},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1080/10643389.2021.1886556","doi":"https://doi.org/10.1080/10643389.2021.1886556","is_oa":false,"landing_page_url":"https://doi.org/10.1080/10643389.2021.1886556","pdf_url":null,"source":{"id":"https://openalex.org/S207935976","display_name":"Critical Reviews in Environmental Science and Technology","issn_l":"1064-3389","issn":["1064-3389","1547-6537"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Reviews in Environmental Science and Technology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1285365094","display_name":null,"funder_award_id":"2 162100 5","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8965758679","display_name":null,"funder_award_id":"21976157","funder_id":"https://openalex.org/F4320322271","funder_display_name":"Science Fund for Creative Research Groups"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322271","display_name":"Science Fund for Creative Research Groups","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":93,"referenced_works":["https://openalex.org/W110484823","https://openalex.org/W1007495478","https://openalex.org/W1841600388","https://openalex.org/W1964921030","https://openalex.org/W1969107063","https://openalex.org/W1970016764","https://openalex.org/W1970940769","https://openalex.org/W1971463803","https://openalex.org/W1973514297","https://openalex.org/W1977883339","https://openalex.org/W1987488902","https://openalex.org/W1990618515","https://openalex.org/W1990857412","https://openalex.org/W1992990880","https://openalex.org/W1994718842","https://openalex.org/W2000006754","https://openalex.org/W2001246172","https://openalex.org/W2002115481","https://openalex.org/W2003400440","https://openalex.org/W2004898895","https://openalex.org/W2010442005","https://openalex.org/W2011281283","https://openalex.org/W2018431021","https://openalex.org/W2019656832","https://openalex.org/W2019929308","https://openalex.org/W2028144245","https://openalex.org/W2030495254","https://openalex.org/W2033438697","https://openalex.org/W2036453518","https://openalex.org/W2041303310","https://openalex.org/W2042524106","https://openalex.org/W2043672781","https://openalex.org/W2049917295","https://openalex.org/W2056238190","https://openalex.org/W2059663974","https://openalex.org/W2062760602","https://openalex.org/W2069244169","https://openalex.org/W2070530203","https://openalex.org/W2070678994","https://openalex.org/W2078284700","https://openalex.org/W2078929235","https://openalex.org/W2083618717","https://openalex.org/W2090278017","https://openalex.org/W2090305068","https://openalex.org/W2096141473","https://openalex.org/W2101801424","https://openalex.org/W2104103595","https://openalex.org/W2105576979","https://openalex.org/W2111464473","https://openalex.org/W2121208009","https://openalex.org/W2133554081","https://openalex.org/W2134199842","https://openalex.org/W2136016660","https://openalex.org/W2138813414","https://openalex.org/W2142420140","https://openalex.org/W2147604426","https://openalex.org/W2163238434","https://openalex.org/W2232390271","https://openalex.org/W2264098572","https://openalex.org/W2274939513","https://openalex.org/W2319646874","https://openalex.org/W2332969818","https://openalex.org/W2340679729","https://openalex.org/W2412905839","https://openalex.org/W2515907736","https://openalex.org/W2518822088","https://openalex.org/W2529531664","https://openalex.org/W2560702716","https://openalex.org/W2606422217","https://openalex.org/W2609362960","https://openalex.org/W2751759157","https://openalex.org/W2754830336","https://openalex.org/W2795174479","https://openalex.org/W2809520587","https://openalex.org/W2899224497","https://openalex.org/W2902746561","https://openalex.org/W2903123935","https://openalex.org/W2913899896","https://openalex.org/W2922876981","https://openalex.org/W2932245060","https://openalex.org/W2944857720","https://openalex.org/W2952305169","https://openalex.org/W2990647528","https://openalex.org/W2991233495","https://openalex.org/W3004593383","https://openalex.org/W3004827378","https://openalex.org/W3013462309","https://openalex.org/W3014353851","https://openalex.org/W3023285337","https://openalex.org/W3025021559","https://openalex.org/W3048009008","https://openalex.org/W4243002209","https://openalex.org/W4254284586"],"related_works":["https://openalex.org/W4200227512","https://openalex.org/W4396743217","https://openalex.org/W2902746561","https://openalex.org/W4394952659","https://openalex.org/W4285183935","https://openalex.org/W4408177065","https://openalex.org/W7161122544","https://openalex.org/W4372341445","https://openalex.org/W3004827378","https://openalex.org/W7166677902"],"abstract_inverted_index":{"Perfluoroalkyl":[0],"and":[1,14,31,39,64,90,97,166,175,193],"polyfluoroalkyl":[2],"substances":[3,7],"(PFASs)":[4],"are":[5,33],"anthropogenic":[6],"of":[8,67,119,170,183,189],"increasing":[9],"concerns.":[10],"Their":[11],"widespread":[12],"uses":[13],"strong":[15],"persistence":[16],"in":[17,29,94,123,191],"the":[18,83,87,91,95,124,138,144,160,164,184],"environment":[19],"have":[20],"led":[21],"to":[22,35,55,71,108,129],"inevitable":[23],"exposure":[24,118],"for":[25,100],"humans.":[26],"They":[27],"accumulate":[28],"mothers":[30,70],"then":[32],"transferred":[34],"infants":[36,120,149],"through":[37,121,134],"placenta":[38],"breastfeeding,":[40],"causing":[41],"diverse":[42],"potential":[43,152],"health":[44,153,187],"risks.":[45,154],"Based":[46,142],"on":[47,62,82,143,163],"more":[48],"than":[49,114,132],"100":[50],"articles":[51],"published":[52],"from":[53,69,106],"2000":[54],"date,":[56],"this":[57,158],"review":[58,162],"summarizes":[59],"current":[60],"knowledge":[61],"prenatal":[63,165],"postnatal":[65,167],"transfer":[66,74,136,169],"PFASs":[68,171,190],"fetuses/infants.":[72],"Transplacental":[73],"efficiencies":[75],"(RCM)":[76],"differ":[77],"among":[78],"individual":[79],"PFASs,":[80],"depending":[81],"alkyl":[84],"chain":[85],"length,":[86],"function":[88],"groups,":[89],"branching":[92],"position":[93],"molecule,":[96],"showing":[98],"enantioselectivity":[99],"chiral":[101],"1":[102],"m-PFOS.":[103],"Transfer":[104],"efficiency":[105],"serum":[107],"breast":[109],"milk":[110],"(TEBS/MS)":[111],"is":[112,159],"lower":[113],"RCM,":[115],"but":[116],"PFAS":[117],"breastfeeding":[122],"first":[125,161],"month":[126],"was":[127],"assessed":[128],"be":[130],"greater":[131,197],"that":[133],"transplacental":[135],"during":[137],"entire":[139],"gestation":[140],"period.":[141],"latest":[145],"promulgated":[146],"reference":[147],"doses,":[148],"would":[150],"face":[151],"To":[155],"our":[156],"knowledge,":[157],"mother-to-offspring":[168],"at":[172],"congeneric,":[173],"isomeric,":[174],"enantiomeric":[176],"levels.":[177],"It":[178],"provides":[179],"a":[180],"better":[181],"understanding":[182],"critical":[185],"environmental":[186],"issue":[188],"fetuses":[192],"infants,":[194],"which":[195],"deserves":[196],"attention":[198],"throughout":[199],"society.":[200]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2021-03-01T00:00:00"}