{"id":"https://openalex.org/W3131556655","doi":"https://doi.org/10.2139/ssrn.3746791","title":"Proangiogenic Collagen Binding Glycan Therapeutic Promotes Endothelial Cell Health: Potential Application for the Treatment of Ischemic Wounds","display_name":"Proangiogenic Collagen Binding Glycan Therapeutic Promotes Endothelial Cell Health: Potential Application for the Treatment of Ischemic Wounds","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3131556655","doi":"https://doi.org/10.2139/ssrn.3746791","mag":"3131556655"},"language":"en","primary_location":{"id":"doi:10.2139/ssrn.3746791","doi":"https://doi.org/10.2139/ssrn.3746791","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3746791","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.3746791","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087870138","display_name":"Tanaya Walimbe","orcid":"https://orcid.org/0000-0002-7561-4379","observed_orcids":["https://orcid.org/0000-0002-7561-4379"]},"institutions":[{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tanaya Walimbe","raw_affiliation_strings":["Department of Biomedical Engineering, University of California","Department of Biomedical Engineering, University of California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of California","institution_ids":["https://openalex.org/I2803209242"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of California, United States","institution_ids":["https://openalex.org/I2803209242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054772078","display_name":"Tima Dehghani","orcid":"https://orcid.org/0000-0001-7563-2668","observed_orcids":["https://orcid.org/0000-0001-7563-2668"]},"institutions":[{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tima Dehghani","raw_affiliation_strings":["Department of Biomedical Engineering, University of California","Department of Biomedical Engineering, University of California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of California","institution_ids":["https://openalex.org/I2803209242"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of California, United States","institution_ids":["https://openalex.org/I2803209242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029794580","display_name":"Alena Casella","orcid":"https://orcid.org/0000-0001-7520-9966","observed_orcids":["https://orcid.org/0000-0001-7520-9966"]},"institutions":[{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alena Casella","raw_affiliation_strings":["Department of Biomedical Engineering, University of California","Department of Biomedical Engineering, University of California, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of California","institution_ids":["https://openalex.org/I2803209242"]},{"raw_affiliation_string":"Department of Biomedical Engineering, University of California, United States","institution_ids":["https://openalex.org/I2803209242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103981239","display_name":"Jenny B. Lin","orcid":"https://orcid.org/0009-0008-3718-2908","observed_orcids":["https://orcid.org/0009-0008-3718-2908"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jenny Lin","raw_affiliation_strings":["Department of Surgery, Indiana University School of Medicine","Department of Surgery, Indiana University School of Medicine, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, Indiana University School of Medicine","institution_ids":["https://openalex.org/I4394709130"]},{"raw_affiliation_string":"Department of Surgery, Indiana University School of Medicine, United States","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100675356","display_name":"Aijun Wang","orcid":"https://orcid.org/0000-0002-2985-3627","observed_orcids":["https://orcid.org/0000-0002-2985-3627"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aijun Wang","raw_affiliation_strings":["University of California Davis, Surgical Bioengineering Laboratory, Department of Surgery,","University of California Davis, Surgical Bioengineering Laboratory, Department of Surgery, Davis, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Davis, Surgical Bioengineering Laboratory, Department of Surgery,","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"University of California Davis, Surgical Bioengineering Laboratory, Department of Surgery, Davis, CA, United States","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085637012","display_name":"Alyssa Panitch","orcid":"https://orcid.org/0000-0002-0360-1480","observed_orcids":["https://orcid.org/0000-0002-0360-1480"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alyssa Panitch","raw_affiliation_strings":["University of California, Davis - Department of Biomedical Engineering","University of California, Davis - Department of Biomedical Engineering, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, Davis - Department of Biomedical Engineering","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"University of California, Davis - Department of Biomedical Engineering, United States","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5085637012"],"corresponding_institution_ids":["https://openalex.org/I84218800"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.011099999770522118,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integrin-alphavbeta3","display_name":"integrin \u03b1v\u03b23","score":0.9480000138282776},{"id":"https://openalex.org/keywords/vegf-signaling","display_name":"VEGF signaling","score":0.9470000267028809},{"id":"https://openalex.org/keywords/vegfr2-phosphorylation","display_name":"VEGFR2 phosphorylation","score":0.9769999980926514},{"id":"https://openalex.org/keywords/diabetic-wound-healing","display_name":"diabetic wound healing","score":0.7319999933242798},{"id":"https://openalex.org/keywords/ischemic-wounds","display_name":"ischemic wounds","score":0.972000002861023},{"id":"https://openalex.org/keywords/peripheral-arterial-disease","display_name":"peripheral arterial disease","score":0.9359999895095825},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation-and-migration","display_name":"endothelial cell proliferation and migration","score":0.8339999914169312},{"id":"https://openalex.org/keywords/collagen-hydrogel","display_name":"collagen gel","score":0.8949999809265137},{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.7900000214576721},{"id":"https://openalex.org/keywords/chick-chorioallantoic-membrane-assay","display_name":"chick chorioallantoic membrane assay","score":0.8190000057220459}],"concepts":[{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.7263039350509644},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4686915874481201},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.43433570861816406},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42279481887817383},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3988373875617981},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35902655124664307},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.21725857257843018},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20286127924919128},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.0},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2139/ssrn.3746791","doi":"https://doi.org/10.2139/ssrn.3746791","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3746791","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2139/ssrn.3746791","doi":"https://doi.org/10.2139/ssrn.3746791","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.3746791","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SSRN Electronic Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1153606301","https://openalex.org/W1967348819","https://openalex.org/W1969442477","https://openalex.org/W1973668238","https://openalex.org/W1986302298","https://openalex.org/W1994471498","https://openalex.org/W1996332681","https://openalex.org/W1996910230","https://openalex.org/W2000453685","https://openalex.org/W2007824685","https://openalex.org/W2014077602","https://openalex.org/W2017444991","https://openalex.org/W2024211867","https://openalex.org/W2024623214","https://openalex.org/W2025667311","https://openalex.org/W2026186036","https://openalex.org/W2030615367","https://openalex.org/W2036395308","https://openalex.org/W2037618281","https://openalex.org/W2037863500","https://openalex.org/W2039284766","https://openalex.org/W2042261220","https://openalex.org/W2050463140","https://openalex.org/W2056064788","https://openalex.org/W2061783448","https://openalex.org/W2067691626","https://openalex.org/W2070013317","https://openalex.org/W2072755205","https://openalex.org/W2082941476","https://openalex.org/W2098767125","https://openalex.org/W2105524188","https://openalex.org/W2117137845","https://openalex.org/W2122208924","https://openalex.org/W2126946832","https://openalex.org/W2139556098","https://openalex.org/W2140247836","https://openalex.org/W2142041241","https://openalex.org/W2153401510","https://openalex.org/W2158968180","https://openalex.org/W2172778470","https://openalex.org/W2588001782","https://openalex.org/W2729854624","https://openalex.org/W2793801139","https://openalex.org/W2803326208","https://openalex.org/W3045682385","https://openalex.org/W4211225433","https://openalex.org/W4246009465","https://openalex.org/W4252043467","https://openalex.org/W7073951773"],"related_works":["https://openalex.org/W3174000967","https://openalex.org/W3200700101","https://openalex.org/W4322620454","https://openalex.org/W6964078046","https://openalex.org/W7119662431","https://openalex.org/W2007357135","https://openalex.org/W3134029611","https://openalex.org/W4407482094","https://openalex.org/W7163661097","https://openalex.org/W1845549666"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2021-03-01T00:00:00"}
