{"id":"https://openalex.org/W3131507412","doi":"https://doi.org/10.1002/9781119671336.ch15","title":"Gamma\u2013Delta T\u2010cell Lymphomas","display_name":"Gamma\u2013Delta T\u2010cell Lymphomas","publication_year":2021,"publication_date":"2021-02-19","ids":{"openalex":"https://openalex.org/W3131507412","doi":"https://doi.org/10.1002/9781119671336.ch15","mag":"3131507412"},"language":"en","primary_location":{"id":"doi:10.1002/9781119671336.ch15","doi":"https://doi.org/10.1002/9781119671336.ch15","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781119671336.ch15","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Peripheral T\u2010Cell Lymphomas","raw_type":"other"},"volume":{"id":"https://openalex.org/W4233982834","display_name":"The Peripheral T\u2010Cell Lymphomas"},"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048583088","display_name":"Francine M. Foss","orcid":"https://orcid.org/0000-0001-7843-3162","observed_orcids":["https://orcid.org/0000-0001-7843-3162"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Francine Foss","raw_affiliation_strings":["Department of Hematology, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087573973","display_name":"Aadil Ahmed","orcid":"https://orcid.org/0000-0001-8934-4800","observed_orcids":["https://orcid.org/0000-0001-8934-4800"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aadil Ahmed","raw_affiliation_strings":["Department of Hematology, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071505679","display_name":"Mina L. Xu","orcid":"https://orcid.org/0000-0001-9513-245X","observed_orcids":["https://orcid.org/0000-0001-9513-245X"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mina Xu","raw_affiliation_strings":["Department Pathology, Yale University School of Medicine, New Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Pathology, Yale University School of Medicine, New Haven, CT, USA","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"203","last_page":"210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11811","display_name":"Cutaneous lymphoproliferative disorders research","score":0.9589999914169312,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11811","display_name":"Cutaneous lymphoproliferative disorders research","score":0.9589999914169312,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.038600001484155655,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gamma-delta-t-cell-lymphoma","display_name":"gamma delta T-cell lymphoma","score":0.9869999885559082},{"id":"https://openalex.org/keywords/primary-cutaneous-gamma-delta-t-cell-lymphoma","display_name":"primary cutaneous gamma-delta T-cell lymphoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hepatosplenic-t-cell-lymphoma","display_name":"hepatosplenic T-cell lymphoma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/who-lymphoma-classification","display_name":"WHO classification of lymphoid neoplasms","score":0.843999981880188},{"id":"https://openalex.org/keywords/chronic-antigen-stimulation","display_name":"chronic antigenic stimulation","score":0.949999988079071},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9779999852180481},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.8259999752044678},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/skin-ulcers","display_name":"skin ulcers","score":0.7900000214576721},{"id":"https://openalex.org/keywords/hemophagocytic-lymphohistiocytosis","display_name":"hemophagocytic lymphohistiocytosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/cns-prophylaxis","display_name":"CNS prophylaxis","score":0.8949999809265137},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9900000095367432},{"id":"https://openalex.org/keywords/stem-cell-transplantation","display_name":"stem cell transplantation","score":0.8970000147819519}],"concepts":[{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.6078647971153259},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.5751233696937561},{"id":"https://openalex.org/C2778993397","wikidata":"https://www.wikidata.org/wiki/Q3077796","display_name":"Gamma delta T cell","level":5,"score":0.5596404671669006},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5442739129066467},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.5116358399391174},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49697068333625793},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.42281997203826904},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.41988372802734375},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2754678428173065},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.19115155935287476}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781119671336.ch15","doi":"https://doi.org/10.1002/9781119671336.ch15","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781119671336.ch15","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Peripheral T\u2010Cell Lymphomas","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1495392944","https://openalex.org/W1517807534","https://openalex.org/W1570507786","https://openalex.org/W1964187235","https://openalex.org/W1966734506","https://openalex.org/W1966991261","https://openalex.org/W1977198374","https://openalex.org/W1980761607","https://openalex.org/W2064224575","https://openalex.org/W2069702840","https://openalex.org/W2070709534","https://openalex.org/W2096850086","https://openalex.org/W2152048536","https://openalex.org/W2166380116","https://openalex.org/W2267761252","https://openalex.org/W2310716991","https://openalex.org/W2416844197","https://openalex.org/W2523404549","https://openalex.org/W2549372514","https://openalex.org/W2807802402","https://openalex.org/W2894766473"],"related_works":["https://openalex.org/W2536052894","https://openalex.org/W931627876","https://openalex.org/W4400164181","https://openalex.org/W1998646967","https://openalex.org/W4283274469","https://openalex.org/W3192795337","https://openalex.org/W799517441","https://openalex.org/W7154953802","https://openalex.org/W2935316909","https://openalex.org/W2809433573"],"abstract_inverted_index":{"The":[0,21],"gamma\u2013delta":[1,13,36,42,71],"T-cell":[2,8,33,43,49,72],"lymphomas":[3,9,28,34,44,50],"are":[4,67,139],"rare":[5],"and":[6,46,57,65,97],"aggressive":[7],"which":[10],"arise":[11],"from":[12],"T":[14],"cells":[15],"in":[16,136],"the":[17,39,47,55,82],"innate":[18],"immune":[19],"system.":[20],"World":[22],"Health":[23],"Organization":[24],"(WHO)":[25],"classification":[26],"for":[27,70,87],"recognizes":[29],"distinct":[30],"subtypes":[31],"of":[32,35,60,75,95,102,117],"subtype,":[37],"including":[38],"primary":[40],"cutaneous":[41],"(PCGTDL)":[45],"hepatosplenic":[48],"(HSTL).":[51],"This":[52],"chapter":[53],"reviews":[54],"biological":[56],"clinical":[58],"features":[59],"PCGDTL.":[61],"Chronic":[62],"antigenic":[63],"stimulation":[64],"immunosuppression":[66],"risk":[68],"factors":[69],"lymphomas.":[73],"Because":[74],"its":[76],"resistance":[77],"to":[78,106,128],"most":[79,120],"chemotherapeutic":[80],"agents,":[81],"overall":[83,100],"prognosis":[84],"is":[85],"poor":[86],"patients":[88,121,137],"with":[89,91,109,122,133],"PCGDTL,":[90,123],"a":[92,98],"median":[93],"survival":[94,101],"15months":[96],"five-year":[99],"10%.":[103],"Patients":[104],"succumb":[105],"morbidity":[107],"associated":[108],"extensive":[110],"skin":[111],"ulcerations":[112],"as":[113,115],"well":[114],"complications":[116],"HLH.":[118],"In":[119],"consideration":[124],"should":[125],"be":[126],"given":[127],"central":[129],"nervous":[130],"system":[131],"prophylaxis":[132],"systemic":[134],"methotrexate":[135],"who":[138],"undergoing":[140],"potentially":[141],"curative":[142],"stem-cell":[143],"transplantation.":[144]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2021-03-01T00:00:00"}