{"id":"https://openalex.org/W3131340693","doi":"https://doi.org/10.1007/s00580-021-03220-5","title":"Attenuation of diabetic nephropathy in alloxan-induced diabetic rats by Solanum macrocarpon Linn aqueous leaves extract","display_name":"Attenuation of diabetic nephropathy in alloxan-induced diabetic rats by Solanum macrocarpon Linn aqueous leaves extract","publication_year":2021,"publication_date":"2021-02-17","ids":{"openalex":"https://openalex.org/W3131340693","doi":"https://doi.org/10.1007/s00580-021-03220-5","mag":"3131340693"},"language":"en","primary_location":{"id":"doi:10.1007/s00580-021-03220-5","doi":"https://doi.org/10.1007/s00580-021-03220-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00580-021-03220-5","pdf_url":null,"source":{"id":"https://openalex.org/S4210222653","display_name":"Comparative Clinical Pathology","issn_l":"0938-7714","issn":["0938-7714","1433-2973","1618-5641","1618-565X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comparative Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065551591","display_name":"Lisa Ilobekemen Ekakitie","orcid":"https://orcid.org/0000-0002-3799-0103","observed_orcids":["https://orcid.org/0000-0002-3799-0103"]},"institutions":[{"id":"https://openalex.org/I29787537","display_name":"Afe Babalola University","ror":"https://ror.org/03rsm0k65","country_code":"NG","type":"education","lineage":["https://openalex.org/I29787537"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"L. Ekakitie","raw_affiliation_strings":["Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria","institution_ids":["https://openalex.org/I29787537"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014705912","display_name":"Basiru Olaitan Ajiboye","orcid":"https://orcid.org/0000-0001-5982-2322","observed_orcids":["https://orcid.org/0000-0001-5982-2322"]},"institutions":[{"id":"https://openalex.org/I29787537","display_name":"Afe Babalola University","ror":"https://ror.org/03rsm0k65","country_code":"NG","type":"education","lineage":["https://openalex.org/I29787537"]}],"countries":["NG"],"is_corresponding":true,"raw_author_name":"B. O. Ajiboye","raw_affiliation_strings":["Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria"],"raw_orcid":"https://orcid.org/0000-0001-5982-2322","affiliations":[{"raw_affiliation_string":"Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria","institution_ids":["https://openalex.org/I29787537"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029887767","display_name":"Babatunji Emmanuel Oyinloye","orcid":"https://orcid.org/0000-0003-2165-7936","observed_orcids":["https://orcid.org/0000-0003-2165-7936"]},"institutions":[{"id":"https://openalex.org/I12553626","display_name":"University of Zululand","ror":"https://ror.org/03v8ter60","country_code":"ZA","type":"education","lineage":["https://openalex.org/I12553626"]},{"id":"https://openalex.org/I29787537","display_name":"Afe Babalola University","ror":"https://ror.org/03rsm0k65","country_code":"NG","type":"education","lineage":["https://openalex.org/I29787537"]}],"countries":["NG","ZA"],"is_corresponding":false,"raw_author_name":"B. E. Oyinloye","raw_affiliation_strings":["Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, 3886, South Africa","Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotechnology and Structural Biology (BSB) Group, Department of Biochemistry and Microbiology, University of Zululand, KwaDlangezwa, 3886, South Africa","institution_ids":["https://openalex.org/I12553626"]},{"raw_affiliation_string":"Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria","institution_ids":["https://openalex.org/I29787537"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065113356","display_name":"O. S. Owero-ozeze","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29787537","display_name":"Afe Babalola University","ror":"https://ror.org/03rsm0k65","country_code":"NG","type":"education","lineage":["https://openalex.org/I29787537"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O. S. Owero-ozeze","raw_affiliation_strings":["Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria","institution_ids":["https://openalex.org/I29787537"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024364229","display_name":"Sunday Amos Onikanni","orcid":"https://orcid.org/0000-0003-0491-3301","observed_orcids":["https://orcid.org/0000-0003-0491-3301","https://orcid.org/0000-0003-4866-8467"]},"institutions":[{"id":"https://openalex.org/I29787537","display_name":"Afe Babalola University","ror":"https://ror.org/03rsm0k65","country_code":"NG","type":"education","lineage":["https://openalex.org/I29787537"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"S. A. Onikanni","raw_affiliation_strings":["Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria","institution_ids":["https://openalex.org/I29787537"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089070522","display_name":"Oluwafemi Adeleke Ojo","orcid":"https://orcid.org/0000-0001-9331-396X","observed_orcids":["https://orcid.org/0000-0001-9331-396X"]},"institutions":[{"id":"https://openalex.org/I29787537","display_name":"Afe Babalola University","ror":"https://ror.org/03rsm0k65","country_code":"NG","type":"education","lineage":["https://openalex.org/I29787537"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O. A. Ojo","raw_affiliation_strings":["Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Phytomedicine, Biochemical Toxicology and Biotechnology Research Laboratory, Department of Biochemistry, College of Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria","institution_ids":["https://openalex.org/I29787537"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5014705912"],"corresponding_institution_ids":["https://openalex.org/I29787537"],"apc_list":{"value":3280,"currency":"USD","value_usd":3280},"apc_paid":null,"fwci":1.0272,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.73028747,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"30","issue":"2","first_page":"173","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.005900000222027302,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.9789999723434448},{"id":"https://openalex.org/keywords/solanum-macrocarpon","display_name":"Solanum macrocarpon","score":0.9929999709129333},{"id":"https://openalex.org/keywords/alloxan-induced-diabetes","display_name":"alloxan-induced diabetes","score":0.8799999952316284},{"id":"https://openalex.org/keywords/aqueous-leaf-extract","display_name":"aqueous leaf extract","score":0.8569999933242798},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.8080000281333923},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9610000252723694},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.6209999918937683},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5379999876022339},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.5350000262260437},{"id":"https://openalex.org/keywords/uric-acid","display_name":"uric acid","score":0.5389999747276306},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.4090000092983246}],"concepts":[{"id":"https://openalex.org/C2779922275","wikidata":"https://www.wikidata.org/wiki/Q1129105","display_name":"Diabetic nephropathy","level":3,"score":0.7554634809494019},{"id":"https://openalex.org/C2781005915","wikidata":"https://www.wikidata.org/wiki/Q417701","display_name":"Alloxan","level":3,"score":0.7065415382385254},{"id":"https://openalex.org/C2993907526","wikidata":"https://www.wikidata.org/wiki/Q1259977","display_name":"Aqueous extract","level":2,"score":0.5948886871337891},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5095920562744141},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.450560063123703},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.428054541349411},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1765020191669464}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s00580-021-03220-5","doi":"https://doi.org/10.1007/s00580-021-03220-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00580-021-03220-5","pdf_url":null,"source":{"id":"https://openalex.org/S4210222653","display_name":"Comparative Clinical Pathology","issn_l":"0938-7714","issn":["0938-7714","1433-2973","1618-5641","1618-565X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comparative Clinical Pathology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W2052201806","https://openalex.org/W2069132215","https://openalex.org/W2082047957","https://openalex.org/W2142907428","https://openalex.org/W2146911942","https://openalex.org/W2187293969","https://openalex.org/W2335364913","https://openalex.org/W2464489801","https://openalex.org/W2466901520","https://openalex.org/W2467118942","https://openalex.org/W2790505242","https://openalex.org/W2889779307","https://openalex.org/W2894274252","https://openalex.org/W2973029183","https://openalex.org/W3023773984","https://openalex.org/W3103580899","https://openalex.org/W3105399587","https://openalex.org/W3194791804","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W3038385683","https://openalex.org/W7212366183","https://openalex.org/W4396669899","https://openalex.org/W2909848347","https://openalex.org/W2557867498","https://openalex.org/W2883490817","https://openalex.org/W7169956496","https://openalex.org/W2146979664","https://openalex.org/W12800831","https://openalex.org/W2294169501"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2021-03-01T00:00:00"}