{"id":"https://openalex.org/W3130073786","doi":"https://doi.org/10.1016/j.gene.2021.145487","title":"Lipopolysaccharide-induced TNF\u03b1 factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio","display_name":"Lipopolysaccharide-induced TNF\u03b1 factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio","publication_year":2021,"publication_date":"2021-02-15","ids":{"openalex":"https://openalex.org/W3130073786","doi":"https://doi.org/10.1016/j.gene.2021.145487","mag":"3130073786","pmid":"https://pubmed.ncbi.nlm.nih.gov/33588039"},"language":"en","primary_location":{"id":"doi:10.1016/j.gene.2021.145487","doi":"https://doi.org/10.1016/j.gene.2021.145487","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2021.145487","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058602112","display_name":"Kangyong Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kangyong Chen","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060674834","display_name":"Jiayin Tian","orcid":"https://orcid.org/0000-0001-9887-7211","observed_orcids":["https://orcid.org/0000-0001-9887-7211"]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiayin Tian","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101758494","display_name":"Junya Wang","orcid":"https://orcid.org/0000-0003-4440-9409","observed_orcids":["https://orcid.org/0000-0003-4440-9409"]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junya Wang","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101704563","display_name":"Zhao Jia","orcid":"https://orcid.org/0000-0001-6972-8209","observed_orcids":["https://orcid.org/0000-0001-6972-8209"]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao Jia","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100418240","display_name":"Qin Zhang","orcid":"https://orcid.org/0009-0009-5451-4051","observed_orcids":["https://orcid.org/0009-0009-5451-4051"]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin Zhang","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100569000","display_name":"Wenji Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenji Huang","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030254419","display_name":"Xin Zhao","orcid":"https://orcid.org/0000-0001-9798-7865","observed_orcids":["https://orcid.org/0000-0001-9798-7865"]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Zhao","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101848978","display_name":"Zhipeng Gao","orcid":"https://orcid.org/0000-0001-7787-285X","observed_orcids":["https://orcid.org/0000-0001-7787-285X"]},"institutions":[{"id":"https://openalex.org/I52180223","display_name":"Hunan Agricultural University","ror":"https://ror.org/01dzed356","country_code":"CN","type":"education","lineage":["https://openalex.org/I52180223"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhipeng Gao","raw_affiliation_strings":["Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China","institution_ids":["https://openalex.org/I52180223"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053984606","display_name":"Qian Gao","orcid":"https://orcid.org/0000-0003-1784-8991","observed_orcids":["https://orcid.org/0000-0003-1784-8991"]},"institutions":[{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Gao","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052813352","display_name":"Jun Zou","orcid":"https://orcid.org/0000-0003-1440-9029","observed_orcids":["https://orcid.org/0000-0003-1440-9029"]},"institutions":[{"id":"https://openalex.org/I4210113896","display_name":"Qingdao National Laboratory for Marine Science and Technology","ror":"https://ror.org/026sv7t11","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210113896"]},{"id":"https://openalex.org/I44675526","display_name":"Shanghai Ocean University","ror":"https://ror.org/04n40zv07","country_code":"CN","type":"education","lineage":["https://openalex.org/I44675526"]},{"id":"https://openalex.org/I52180223","display_name":"Hunan Agricultural University","ror":"https://ror.org/01dzed356","country_code":"CN","type":"education","lineage":["https://openalex.org/I52180223"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jun Zou","raw_affiliation_strings":["Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China; Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Electronic address: jzou@shou.edu.cn","Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China","International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China; Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China. Electronic address: jzou@shou.edu.cn","institution_ids":["https://openalex.org/I4210113896","https://openalex.org/I44675526","https://openalex.org/I52180223"]},{"raw_affiliation_string":"Hunan Engineering Technology Research Center of Featured Aquatic Resources Utilization, College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China","institution_ids":["https://openalex.org/I52180223"]},{"raw_affiliation_string":"International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China","institution_ids":["https://openalex.org/I44675526"]},{"raw_affiliation_string":"Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China","institution_ids":["https://openalex.org/I4210113896"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5052813352"],"corresponding_institution_ids":["https://openalex.org/I4210113896","https://openalex.org/I44675526","https://openalex.org/I52180223"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":1.1176,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.73868073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"780","issue":null,"first_page":"145487","last_page":"145487"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.9657999873161316,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.9657999873161316,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.028200000524520874,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/litaf","display_name":"LITAF","score":0.8970000147819519},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.9570000171661377},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.6629999876022339},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/caspase-3","display_name":"caspase-3","score":0.9269999861717224},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.9039999842643738},{"id":"https://openalex.org/keywords/poly-i-c","display_name":"poly(I:C)","score":0.7879999876022339},{"id":"https://openalex.org/keywords/edwardsiella-tarda","display_name":"Edwardsiella tarda","score":0.9860000014305115},{"id":"https://openalex.org/keywords/aeromonas-hydrophila","display_name":"Aeromonas hydrophila","score":0.9879999756813049},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.48500001430511475},{"id":"https://openalex.org/keywords/nuclear-translocation","display_name":"nuclear translocation","score":0.6830000281333923},{"id":"https://openalex.org/keywords/endoplasmic-reticulum","display_name":"endoplasmic reticulum","score":0.9039999842643738},{"id":"https://openalex.org/keywords/immune-defense","display_name":"immune defense","score":0.4480000138282776}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9068709015846252},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.7690961360931396},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6207484602928162},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5920469164848328},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.5760904550552368},{"id":"https://openalex.org/C2780384893","wikidata":"https://www.wikidata.org/wiki/Q901804","display_name":"Danio","level":4,"score":0.5553315877914429},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.4907935559749603},{"id":"https://openalex.org/C2776832872","wikidata":"https://www.wikidata.org/wiki/Q3048738","display_name":"Edwardsiella tarda","level":3,"score":0.4376524090766907},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.43309032917022705},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3805184066295624},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3127087354660034},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.24477547407150269},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14649567008018494}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004268","descriptor_name":"DNA-Binding Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D004756","descriptor_name":"Enterobacteriaceae Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005393","descriptor_name":"Fish Diseases","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D005393","descriptor_name":"Fish Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005393","descriptor_name":"Fish Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016905","descriptor_name":"Gram-Negative Bacterial Infections","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016980","descriptor_name":"Aeromonas hydrophila","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D020609","descriptor_name":"Edwardsiella tarda","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D029961","descriptor_name":"Zebrafish Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.gene.2021.145487","doi":"https://doi.org/10.1016/j.gene.2021.145487","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.gene.2021.145487","pdf_url":null,"source":{"id":"https://openalex.org/S75702506","display_name":"Gene","issn_l":"0378-1119","issn":["0378-1119","1879-0038"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"journal-article"},{"id":"pmid:33588039","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33588039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gene","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1868478050","https://openalex.org/W1966634911","https://openalex.org/W1974062075","https://openalex.org/W1978118583","https://openalex.org/W1978693569","https://openalex.org/W1981306774","https://openalex.org/W1983848135","https://openalex.org/W1987541218","https://openalex.org/W2000326511","https://openalex.org/W2008682741","https://openalex.org/W2024639668","https://openalex.org/W2030857394","https://openalex.org/W2038015216","https://openalex.org/W2043789714","https://openalex.org/W2046776183","https://openalex.org/W2058908193","https://openalex.org/W2061294496","https://openalex.org/W2071201507","https://openalex.org/W2078950285","https://openalex.org/W2089074181","https://openalex.org/W2096932850","https://openalex.org/W2100088019","https://openalex.org/W2105783569","https://openalex.org/W2119459816","https://openalex.org/W2124840287","https://openalex.org/W2129443010","https://openalex.org/W2137145041","https://openalex.org/W2400245958","https://openalex.org/W2587416506","https://openalex.org/W2909944994","https://openalex.org/W2947449924","https://openalex.org/W2973859922","https://openalex.org/W2996314280","https://openalex.org/W3007192233"],"related_works":["https://openalex.org/W2996314280","https://openalex.org/W2058908193","https://openalex.org/W1992428440","https://openalex.org/W1987541218","https://openalex.org/W7046200325","https://openalex.org/W574784850","https://openalex.org/W2588016366","https://openalex.org/W1963577601","https://openalex.org/W1983848135","https://openalex.org/W2006086060"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-03-01T00:00:00"}