{"id":"https://openalex.org/W3127059825","doi":"https://doi.org/10.1002/ehf2.13225","title":"Acute Pulmonary Pressure Change After Transition to Sacubitril/Valsartan in Patients with Heart Failure Reduced Ejection Fraction","display_name":"Acute Pulmonary Pressure Change After Transition to Sacubitril/Valsartan in Patients with Heart Failure Reduced Ejection Fraction","publication_year":2021,"publication_date":"2021-01-31","ids":{"openalex":"https://openalex.org/W3127059825","doi":"https://doi.org/10.1002/ehf2.13225","mag":"3127059825","pmid":"https://pubmed.ncbi.nlm.nih.gov/33522140","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/8006690"},"language":"en","primary_location":{"id":"doi:10.1002/ehf2.13225","doi":"https://doi.org/10.1002/ehf2.13225","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ehf2.13225","pdf_url":null,"source":{"id":"https://openalex.org/S2764810254","display_name":"ESC Heart Failure","issn_l":"2055-5822","issn":["2055-5822"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ESC Heart Failure","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1002/ehf2.13225","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078280165","display_name":"Jeffrey Show Tran","orcid":"https://orcid.org/0000-0002-5239-959X","observed_orcids":["https://orcid.org/0000-0002-5239-959X"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey S. Tran","raw_affiliation_strings":["Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019758349","display_name":"Ofer Havakuk","orcid":"https://orcid.org/0000-0002-5097-2698","observed_orcids":["https://orcid.org/0000-0002-5097-2698"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]},{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL","US"],"is_corresponding":false,"raw_author_name":"Ofer Havakuk","raw_affiliation_strings":["Department of Cardiology, Tel Aviv Medical Center, Tel Aviv University , Tel Aviv ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Cardiology, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Tel Aviv Medical Center, Tel Aviv University , Tel Aviv ,","institution_ids":["https://openalex.org/I16391192"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Cardiology, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002769253","display_name":"Jennifer M. McLeod","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer M. McLeod","raw_affiliation_strings":["Department of Medicine, Montefiore Einstein Center for Heart and Vascular Care, Albert Einstein College of Medicine , New York, NY ,","Department of Medicine, Montefiore Einstein Center for Heart and Vascular Care, Albert Einstein College of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Montefiore Einstein Center for Heart and Vascular Care, Albert Einstein College of Medicine , New York, NY ,","institution_ids":["https://openalex.org/I129975664"]},{"raw_affiliation_string":"Department of Medicine, Montefiore Einstein Center for Heart and Vascular Care, Albert Einstein College of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I129975664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102508100","display_name":"Jennifer D. Hwang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Hwang","raw_affiliation_strings":["Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046259749","display_name":"Hoi Yan Kwong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hoi Yan Kwong","raw_affiliation_strings":["Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030898839","display_name":"David M. Shavelle","orcid":"https://orcid.org/0000-0002-9209-9807","observed_orcids":["https://orcid.org/0000-0002-9209-9807","https://orcid.org/0000-0001-8137-9064"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Shavelle","raw_affiliation_strings":["Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047833899","display_name":"Michael R. Zile","orcid":"https://orcid.org/0000-0001-7076-221X","observed_orcids":["https://orcid.org/0000-0001-7076-221X"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael R. Zile","raw_affiliation_strings":["Division of Cardiology, RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina , Charleston, SC ,","Division of Cardiology, RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina, Charleston, SC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina , Charleston, SC ,","institution_ids":["https://openalex.org/I153297377"]},{"raw_affiliation_string":"Division of Cardiology, RHJ Department of Veterans Affairs Medical Center, Medical University of South Carolina, Charleston, SC, USA","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039521418","display_name":"Uri Elkayam","orcid":"https://orcid.org/0000-0003-3150-5709","observed_orcids":["https://orcid.org/0000-0003-3150-5709"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Uri Elkayam","raw_affiliation_strings":["Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001271607","display_name":"Michael Fong","orcid":"https://orcid.org/0000-0002-0874-7059","observed_orcids":["https://orcid.org/0000-0002-0874-7059"]},"institutions":[{"id":"https://openalex.org/I1174212","display_name":"University of Southern California","ror":"https://ror.org/03taz7m60","country_code":"US","type":"education","lineage":["https://openalex.org/I1174212"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael W. Fong","raw_affiliation_strings":["Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC) , Los Angeles, CA ,","institution_ids":["https://openalex.org/I1174212"]},{"raw_affiliation_string":"Department of Internal Medicine, Keck School of Medicine of the University of Southern California (USC), Los Angeles, CA, USA","institution_ids":["https://openalex.org/I1174212"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055469202","display_name":"Luanda P. Grazette","orcid":"https://orcid.org/0000-0002-2674-2526","observed_orcids":["https://orcid.org/0000-0002-2674-2526"]},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Luanda P. Grazette","raw_affiliation_strings":["Cardiovascular Division, Miller School of Medicine, University of Miami , Miami, FL ,","Cardiovascular Division, Miller School of Medicine, University of Miami, Miami, FL, USA"],"raw_orcid":"https://orcid.org/0000-0002-2674-2526","affiliations":[{"raw_affiliation_string":"Cardiovascular Division, Miller School of Medicine, University of Miami , Miami, FL ,","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Cardiovascular Division, Miller School of Medicine, University of Miami, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5055469202"],"corresponding_institution_ids":["https://openalex.org/I145608581"],"apc_list":{"value":3366,"currency":"USD","value_usd":3366},"apc_paid":{"value":3366,"currency":"USD","value_usd":3366},"fwci":4.0193,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.95214634,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"8","issue":"2","first_page":"1706","last_page":"1710"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.8755000233650208,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.8755000233650208,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.07419999688863754,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sacubitril-valsartan","display_name":"sacubitril/valsartan","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pulmonary-artery-pressure","display_name":"pulmonary artery pressure","score":0.9589999914169312},{"id":"https://openalex.org/keywords/heart-failure-with-reduced-ejection-fraction","display_name":"heart failure with reduced ejection fraction","score":0.9819999933242798},{"id":"https://openalex.org/keywords/natriuretic-peptides","display_name":"natriuretic peptides","score":0.8939999938011169},{"id":"https://openalex.org/keywords/renin-angiotensin-aldosterone-system-inhibition","display_name":"renin-angiotensin-aldosterone system inhibition","score":0.859000027179718},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.9049999713897705},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":1.0},{"id":"https://openalex.org/keywords/pulmonary-vasculature","display_name":"pulmonary vasculature","score":0.5979999899864197}],"concepts":[{"id":"https://openalex.org/C2775999527","wikidata":"https://www.wikidata.org/wiki/Q17811448","display_name":"Sacubitril, Valsartan","level":4,"score":0.9374591112136841},{"id":"https://openalex.org/C2776754050","wikidata":"https://www.wikidata.org/wiki/Q17811448","display_name":"Sacubitril","level":4,"score":0.9319815635681152},{"id":"https://openalex.org/C2777387769","wikidata":"https://www.wikidata.org/wiki/Q155472","display_name":"Valsartan","level":3,"score":0.8431533575057983},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7509713768959045},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.7068378329277039},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6929218769073486},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.608471155166626},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.5979999899864197},{"id":"https://openalex.org/C2780940725","wikidata":"https://www.wikidata.org/wiki/Q206280","display_name":"Pulmonary artery","level":2,"score":0.46249058842658997},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.4609419107437134},{"id":"https://openalex.org/C104849204","wikidata":"https://www.wikidata.org/wiki/Q24778533","display_name":"Angiotensin receptor","level":4,"score":0.43298378586769104},{"id":"https://openalex.org/C2908929049","wikidata":"https://www.wikidata.org/wiki/Q65963433","display_name":"Angiotensin II","level":3,"score":0.32249873876571655}],"mesh":[{"descriptor_ui":"D000068756","descriptor_name":"Valsartan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000613","descriptor_name":"Aminobutyrates","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000806","descriptor_name":"Angiotensin-Converting Enzyme Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001713","descriptor_name":"Biphenyl Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006333","descriptor_name":"Heart Failure","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013318","descriptor_name":"Stroke Volume","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015260","descriptor_name":"Neprilysin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057911","descriptor_name":"Angiotensin Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1002/ehf2.13225","doi":"https://doi.org/10.1002/ehf2.13225","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ehf2.13225","pdf_url":null,"source":{"id":"https://openalex.org/S2764810254","display_name":"ESC Heart Failure","issn_l":"2055-5822","issn":["2055-5822"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ESC Heart Failure","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8006690","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8006690","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ESC Heart Fail","raw_type":"Text"},{"id":"pmid:33522140","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33522140","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ESC heart failure","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:bc00bbfc03564b8d8c152d2fb902ea29","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bc00bbfc03564b8d8c152d2fb902ea29","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ESC Heart Failure, Vol 8, Iss 2, Pp 1706-1710 (2021)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/ehf2.13225","doi":"https://doi.org/10.1002/ehf2.13225","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ehf2.13225","pdf_url":null,"source":{"id":"https://openalex.org/S2764810254","display_name":"ESC Heart Failure","issn_l":"2055-5822","issn":["2055-5822"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ESC Heart Failure","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1865246179","https://openalex.org/W1984123284","https://openalex.org/W2001314044","https://openalex.org/W2006950308","https://openalex.org/W2055557680","https://openalex.org/W2113698123","https://openalex.org/W2133931932","https://openalex.org/W2224556300","https://openalex.org/W2789864715","https://openalex.org/W2899147715","https://openalex.org/W2912986738","https://openalex.org/W2951561227","https://openalex.org/W2953528096","https://openalex.org/W2982651646","https://openalex.org/W3006653371"],"related_works":["https://openalex.org/W4280563480","https://openalex.org/W2795130454","https://openalex.org/W3202592489","https://openalex.org/W2887940517","https://openalex.org/W4386353670","https://openalex.org/W2969739125","https://openalex.org/W4410638250","https://openalex.org/W3079452946","https://openalex.org/W4317653958","https://openalex.org/W3181023598"],"abstract_inverted_index":{"AIMS:":[0],"Sacubitril/valsartan":[1],"combines":[2],"renin-angiotensin-aldosterone":[3],"system":[4],"inhibition":[5],"with":[6,65,147,218],"amplification":[7],"of":[8,26,46,122,196],"natriuretic":[9,16],"peptides.":[10],"In":[11,206],"addition":[12],"to":[13,61,95,151,214],"well-described":[14],"effects,":[15],"peptides":[17],"exert":[18],"direct":[19],"effects":[20],"on":[21,28,111],"pulmonary":[22,29],"vasculature.":[23],"The":[24,126,153,190],"effect":[25],"sacubitril/valsartan":[27,62,101,215],"artery":[30],"pressure":[31,91],"(PAP)":[32],"has":[33],"not":[34],"been":[35],"fully":[36],"defined.":[37],"METHODS":[38],"AND":[39],"RESULTS:":[40],"This":[41],"was":[42,140,194,216],"a":[43,72,141],"retrospective":[44,208],"case-series":[45],"PAP":[47,103],"changes":[48,104],"following":[49],"transition":[50,148,211],"from":[51,93,149,212],"angiotensin-converting":[52],"enzyme":[53],"inhibitor":[54],"(ACEI)":[55],"or":[56],"angiotensin":[57],"receptor":[58],"blocker":[59],"(ARB)":[60],"in":[63,144,161,192,224],"patients":[64,109],"heart":[66],"failure":[67],"reduced":[68],"ejection":[69],"fraction":[70],"and":[71,78,99,158,164,182,221],"previously":[73],"implanted":[74],"CardioMEMS\u2122":[75,123],"sensor.":[76],"Pre-sacubitril/valsartan":[77],"post-sacubitril/valsartan":[79],"PAPs":[80,145,166,193],"were":[81,105,167],"compared":[82,107],"for":[83],"each":[84],"patient":[85],"by":[86],"examining":[87],"averaged":[88],"consecutive":[89],"daily":[90],"readings":[92],"1":[94],"5":[96],"days":[97],"before":[98],"after":[100],"exposure.":[102],"also":[106],"between":[108],"based":[110],"elevated":[112],"trans-pulmonary":[113,197],"gradients":[114],"(trans-pulmonary":[115],"gradient":[116,198],"\u2265":[117],"12":[118],"mmHg)":[119],"at":[120],"time":[121],"sensor":[124],"implantation.":[125],"cohort":[127],"included":[128],"18":[129],"patients,":[130],"72%":[131],"male,":[132],"mean":[133],"age":[134],"60.1":[135],"\u00b1":[136],"13.6":[137],"years.":[138],"There":[139],"significant":[142,222],"decrease":[143,191,223],"associated":[146,217],"ACEI/ARB":[150,213],"sacubitril/valsartan.":[152],"median":[154],"(interquartile":[155],"range)":[156],"pre-treatment":[157],"post-treatment":[159],"change":[160],"mean,":[162],"systolic":[163],"diastolic":[165],"-3.6":[168],"(-9.8,":[169],"-0.7)":[170,185],"mmHg":[171,178],"(P":[172,179,186],"<":[173],"0.001),":[174,181,188],"-6.5":[175],"(-15.0,":[176],"-2.0)":[177],"=":[180,187,200,203],"-2.5":[183],"(-5.7,":[184],"respectively.":[189],"independent":[195],"(F(1,16)":[199],"0.49,":[201],"P":[202],"0.49).":[204],"CONCLUSIONS:":[205],"this":[207],"case":[209],"series,":[210],"an":[219],"early":[220],"PAPs.":[225]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2021-02-15T00:00:00"}
